New Services use Phage Display
Immunoprecipitation Sequencing (PhIP-Seq) to Provide Groundbreaking
High-throughput, Proteome-wide Seromic Analysis
TORONTO, July 9, 2024
/PRNewswire/ -- CDI Labs Canada Inc., a leading provider of
services for proteome wide antibody profiling and target
identification, today announced the launch of its
VirScan®, HuScan®, and
MouseScan™ services. These services utilize phage display
immunoprecipitation sequencing (PhIP-Seq), a powerful method of
multiplexed analysis that combines next-generation proteomics with
high-throughput DNA sequencing, to provide researchers with
unparalleled insights into the intricate connection between
antibodies and diseases. With these new services researchers can
now unravel the unique history of an individual's viral exposures,
conduct proteome-wide autoantibody profiling, and discover
potential biomarkers all in a single-well assay with quantitative
sequencing readouts.
"The importance of high-throughput serology is being recognized
more than ever, and proteome scale tools and services allow
scientists to cast the widest possible net for their studies," said
Barney Saunders, PhD, CEO of CDI
Labs, Inc. "Our customers believe that antibodies hold vital
information that can lead to a better understanding of human
diseases and conditions, and we believe that these new libraries
will help them find critical answers faster."
VirScan allows researchers to determine the specific antibodies
created in response to a person's lifetime of viral exposures. The
VirScan PhIP-Seq library is designed to identify antibodies versus
>68,000 annotated viral protein sequences from most known
proteins from human, mammalian, other vertebrate, mosquito-borne,
tick-borne, and other viral genomes. VirScan contains a library
consisting of >480,000 unique peptide sequences.
HuScan and MouseScan services allow for the analysis of samples
(serum, plasma, CSF, etc.) for the presence of autoantibodies
against a full RefSeq human or mouse proteome in a single-well
assay with quantitative sequencing readouts. The HuScan PhIP-Seq
library contains >730,000 unique peptide sequences that
represent a full human proteome of >48,000 proteins and protein
isoforms. The MouseScan PhIP-Seq library contains >480,000
unique peptide sequences that represent a full murine proteome of
~50,000 proteins and protein isoforms.
VirScan, HuScan and MouseScan PhIP-seq service services are
offered exclusively through CDI Labs Canada which is based in
Toronto, Ontario.
About CDI Laboratories, Inc.
CDI Laboratories, a
proteome-technologies company, is a pioneer in the field of
Seromics, empowering researchers to decipher the causative link of
autoantibodies to disease and enabling them to create breakthrough
treatments and diagnostics. CDI provides transformational tools and
services for proteome-wide, autoantibody profiling and target
identification, including the HuProt™ Human Proteome Array,
the world's largest collection of full-length proteins, and a
portfolio of PhIP-Seq services consisting of VirScan, HuScan and
MouseScan. CDI Laboratories also manufactures individual monoclonal
antibodies, and synthesizes proteins at scale for high throughput
screening and other applications. To learn more about the latest
services and technologies offered by CDI Laboratories, please visit
our website at cdilabs.com.
VirScan and HuScan are registered trademarks of CDI
Laboratories, Inc. All other trademarks are the property of their
respective owners. All products described herein are intended FOR
RESEARCH USE ONLY and NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Media Contact
Chris
Grimley
415-425-8864
chris.grimley@cdilabs.com
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content:https://www.prnewswire.com/news-releases/cdi-labs-launches-new-virscan-huscan-and-mousescan-services-for-massively-multiplexed-analysis-of-serum-antibodies-302191341.html
SOURCE CDI Labs Canada Inc.