Scancell Share Discussion Threads

[the real lozan] 08/3/2019 13:27

Pshyco -
YOUR 'flush' of ranting posts today,DOES lead one to accept = The 'point being made'
.
.
.
By Tosh and many, many others

[bermudashorts] 08/3/2019 13:17

Inanaco - seriously why does any of this matter? Whatever point you're trying to make is completely lost in your posts - they're impossible to follow.

[inanaco] 08/3/2019 13:17

Tosh ... has had you guys all along purely based on his obsession for me which he fuels again with words like

"despise"


issue is

ONW
Panama7
Terror
Lozan

are you still stupid enough to believe him ?

time will tell

[inanaco] 08/3/2019 13:14

tosh123 - 13 Sep 2016 - 08:27:08 - 6534 of 20425 Using immunology to fight cancer. - SCLP
GF, now telling agema that he " disagrees " with his views ... not sure how he can disagree when agema is already over 50% correct, and he still has about a week to go.
The big investor also questions why some of us " so called " LTH's arent selling... Thats easy to answer GF, its because we dont have an average price of 18.5p or 18.1p or whatever other number you're likely to pick out of the air over the coming days / weeks.


I am very comfortable with my holding and my average and dont want or need, to sell.

[inanaco] 08/3/2019 13:10

you see you keep telling us you are happy with your position AFTER you posted this



"""""""""" I bought a load at 12.7p you moron."""""""""""""""


tosh123 - 06 Apr 2016 - 15:51:56 - 4876 of 20424 Using immunology to fight cancer. - SCLP
This is just too easy !!!! Still you come out with total rubbish and are WRONG again... I bought a load at 12.7p you moron.
Of course Goodfellow hasn't failed ( in your eyes because you get everything wrong ) he has presided over a period of total shareholder value collapse. He has failed to deliver a deal, even though he has stated that that was his aim on numerous occasions. He has had to now go it alone because neither he or DE delivered. He has overseen 2 capital raises that have diluted shareholder value even further. He has been responsible for a 70% + drop in share price. He has changed tack so many times that i doubt he even knows where he's been or where he's going. He has promised a return to shareholders, but has failed. He stood at the presentation last month and said that money was not an issue as they had enough monet to see them through for at least 12 months, and then announced an OO and a placing the next day... So yes, you are right, of course ha hasn't failed... Brilliant.

[inanaco] 08/3/2019 12:58

tosh123 - 14 Apr 2016 - 14:05:43 - 4989 of 20422 Using immunology to fight cancer. - SCLP
GF123... and still his average is WAY above mine..
But way UNDER yours.. Classic... You're like a present that just keeps on giving.

[inanaco] 08/3/2019 12:55

tosh123 - 02 May 2016 - 14:05:41 - 5333 of 20421 Using immunology to fight cancer. - SCLP
Thats nice and easy to sort out... My average is way under the current SP, WHAT IS YOURS ? Is it under the current share price ? nice simple question that will put this one to bed once and for all.
And you seem to have overlooked the part of my post about W's bet, once again... surely you need to take him up on his wager after all your posts, because surely you need to prove that you were right, otherwise you'll just continue to look like a muppet.

share price 15p ....

""" My average is way under the current share price """"


so that is one post that you admit .... now considering you are holding for a deal and the share price has hardly moved up from that figure but moved down, and indeed you Did NOT buy in around the 10p lows ..as you told us you would NOT .

so who is lying here ...

Freebies with an Average

or

Tosh runs on free shares


tosh123 - 28 Apr 2016 - 09:08:56 - 5266 of 20421 Using immunology to fight cancer. - SCLP
for the millionth time... i am comfortable as my average is very low ( way under the current share price ) despite a purchase at circa 23p and another at circa 13p, its really not rocket science !
As for declaring my trades, this will never happen you idiot ! I have nothing to prove to you, and the fact that you keep demanding such a stupid thing , only goes to reinforce your arrogance, and total lack of understanding of how things work.
Only those with huge ego's feel the need to advertise their holdings and trading activities.


Tosh you are just waffle .........

"i am comfortable with my average"

[tosh123] 08/3/2019 12:27

There's that bad smell back again.... It stinks of total bullsh1te .

[inanaco] 08/3/2019 12:08

Tosh ...

reminder

Don't forget your post that you claimed your "average" was lower than GF123

resultant storm generated the "freebies with an average" post

so ....

Freebies with an average ....... Car Crash

Mouse Posts ......... Car crash

CFD Posts ........... Car Crash

Calling futures lower while not selling ..... Car Crash

failing to tell the BB recently of your disaster investing in other shares (it's in your history) .... Car Crash

But called it Right ...

[tosh123] 08/3/2019 11:01

I doubt there's a sale being negotiated, but even if there was, what price now ? 20p maybe 25p tops.
This would be very nice for any shareholders that are currently in the money, and indeed all of the II's, but it would crucify a lot of small investors like our resident village person, and much as i despise the idiot, i wouldn't want to see so many people get hurt.
Hopefully we are in a closed period, and for other reasons.

It does look like a total shambles though.

[panama7] 08/3/2019 09:54

Gazza, I hope you are right, the sooner someone buys this the better.

[oldnotwise] 08/3/2019 09:53

Gaz like the thought... Brightens the morning up whilst waiting for the garage to replace yet another sensor that's made me drive over here at a steady 50mph... Ain't technology great...
:-)
Wonder when the deal'll be rnsd hehe.
ATB

[gazza] 08/3/2019 09:38

Panama, yes another week of downward drift. I was thinking about this, take all the facts:

SP drifting to near all time low
Wall of silence from BOD - no reassurance re SP, nothing on IND or SCIB2.
5m Shares to move on
Funds WILL be needed quite soon.

Given all the above, why would the BOD be completely silent?
Why would the BOD apparently be unconcerned about the SP?

Perhaps - a sale is being negotiated.

Just a thought AIMO

[panama7] 08/3/2019 08:55

Another week passes still no IND resolution but according to Holloway the trial is on track to commence H1. No corresponding trade for the 5m shares sold on Monday doesn't augur very well for any when upcoming fundraise when no II has picked up the 5m for 6p. Maybe they think any fundraise will be considerably cheaper.

[tosh123] 07/3/2019 11:39

Thank you gentlemen, a very comprehensive response which is much appreciated.

[10acious] 07/3/2019 11:39

So that would appear to mean that Ichor will be a permanent partner for any and all products delivered via their device... ie you can't just buy the device after approval and go it alone!

[oldnotwise] 07/3/2019 11:37

Berm, Please, no worries, mine may be slightly shorter but yours has more meat!!!
Yes we are saying the same thing.
Thanks again for the expansion...
ATB

[bermudashorts] 07/3/2019 11:26

ONW - lol, sorry, was interrupted by phone call so took me ages to type above and your far more succinct 20408 wasn't there when I started. Think we're saying the same thing though:)

[bermudashorts] 07/3/2019 11:24

Tosh,

This is my understanding.

Ichor submit a master file to the FDA (from memory CDRH) division. The master file isn't an application for approval for the device in any way. That's done via a PMA 510k application and I assume the aim will be for Ichor to eventually submit a 510k application with supporting data from Scancell's and other clinical trials. The master file in this context is just a submission to the FDA which will provide them with the information and data needed to support IND applications from Ichor's customers. Ichor lodged their Master File back in Feb 2018. I don't think the file is reviewed at all by the FDA at this stage, it's simply held on record (could be wrong on this).

When an IND application is received by the FDA for a new drug trial that intends to use the Ichor device, it will include an authority for the FDA to access Ichor's master file. The FDA will then review the relevant sections of the master file but only for use for that particular IND. If, the FDA discovers that the master file doesn't contain sufficient info/data to support its use for that trial, it will request that the applicant (Scancell)rectify any deficiencies. Scancell then have to go back to Ichor who will make an amendment to the master file with the supplementary information.

It may be that Scancell's IND is the first the FDA have received for the new Ichor device, in which case any deficiencies in the master file might well also have applied to other IND's and so Scancell's IND might make for an easier journey for any future INDs.

Sorry this is so long winded and I must stress that this is just my own understanding and may well have got it slightly wrong but I think it's important to understand at least a bit about the process as it helps to explain why we are where we are!!

[oldnotwise] 07/3/2019 10:56

Tosh, I hope Bermuda doesn't mind if I join in. The trigrid V2 will ONLY ever be approved for use with a SPECIFIC BIOLOGIC.
Although the delivery system's being used in other trials it is authorised specifically as a delivery system for each trial.
It's not a generically authorised system which will automatically be approved in the future.
CH hasn't said anything different, as far as I can see.
AIMO
ATB

[panama7] 07/3/2019 10:28

Lozan, yes the Markets get it very well. The current share price is very much a reflection of the BOD's performance over a period of 6 years but is not reflected in their rewards.

[tosh123] 07/3/2019 10:28

Berm,
agreed.. but is it not by definition, giving the thumbs up to the delivery device as well as the SCIB 1 combination under the same approval ?
I thought that the approval of the device was just as important as the combo trial sanction ?
If im wrong i will stand corrected, i was just under the impression that both elements were being " approved " at the same time.
Would appreciate your guidance if i have got that wrong.

[the real lozan] 07/3/2019 10:19

Misguided Mantras -
" The S P doesn't matter"
" The market doesn't *GET IT* "
The REALITY is =
The 'market' is not a bunch of 'amateurs' with 'a dwindling financial, over-exposed position' looking for excuses
The 'market' is set / run by experienced Professionals,who KNOW what they are about
.
In Oct 2018 the S P was in the 10p s....some thought that was bad enough
Now the S P has sat in MID/LOW 6p s ...for almost a 'month' { having spent most of the time since Oct 2018 in MID/LOW er 8p s
.
NOT without 'reason'
The S P DOES matter
The 'market' DOES *GET what the 'market' Sees
The 'market' understands RISK / FUNDING / Time scales ETC.
.
Even if those with a 'less-than impartial interest' don't want to/want others to -
SEE what the 'experienced, Professionals' see
The S P is where it is for a REASON... Which is NOT 'cos folks 'Don't GET IT"

[bermudashorts] 07/3/2019 10:17

Tosh,

Just for clarity re. the IND, the FDA aren't looking at approval of the Trigrid device itself - it's only approval for use in the SCIB1 combination trial.

The very reason that Scancell are using the Trigrid device is the very reason why the FDA are going to make sure they are completely satisfied before allowing its use on humans and as you say they're not going to just take someone's word for it or nod it through because an old version of the device had no issues.

You have:-

A checkpoint inhibitor, which can in itself lead to hyperactive immune responses being combined with SCIB1 which generates a potent immune response and is delivered by a device which amplifies that immune response by 100 fold. It's powerful stuff and of course as the original SCIB1 trial wasn't run in the US it's the first time the FDA have looked at it.

Having said all that, wish they'd hurry up.