Scancell Share Discussion Threads

[chillpill] 17/4/2021 10:14

Whilst we have the quiet period before the impending commencement of the trials I found it good to recap on the BioNTech collaboration that started 3 years ago. I see they now have a mere €36bn market at the moment which highlights the huge potential upside if SCLP are successful. Redmile came across SCLP via BioNTech. httPS://www.proactiveinvestors.co.uk/companies/news/308611/scancell-research-collaboration-deal-with-european-biopharma-biontech-8611.html

[torquayfan] 17/4/2021 10:12

"Covid-19 Disease Triggers More Ultra-Rare Blood Clots Than Vaccines, Study Finds" "The risk of contracting blood clots is much higher for Covid-19 patients than from vaccines, according to a study released on Thursday. The rare blood clotting known as cerebral venous thrombosis, or CVT, occurred at a rate of 39 per million Covid 19 patients, according to researchers at the University of Oxford, the same university that helped develop the AstraZeneca vaccine." https://finance.yahoo.com/m/33195e37-6ccc-3511-a87a-11bf7435e164/covid-19-disease-triggers.html

[goyathlay] 16/4/2021 18:08

! ""German media say doctors have been guessing people’s age from their first names to contact them for vaccination - Ursula is rare for under 60s, so is Brunhilda - because the country’s data laws prevent centralised records. "" htTps://www.telegraph.co.uk/business/2021/04/16/germany-warns-lasting-economic-damage-covid-cases-spin-control/ Not sure if there is any data on 'Adolf'. Or 'Broomsticks'. Let's have a tune to cheer up our German friends . htTps://www.youtube.com/watch?v=geFJ4hYTt5g

[emptyend] 16/4/2021 16:44

.....half the day's (modest) volume in one purchase at 23p.Not much seems to be happening - but developments are surely afoot, given that vaccine batches are clearly being completed by Cobra.Does anyone know the technical details of how the speed to production of vaccine batches compares with others? Or the scaleability of the process?

[panama7] 16/4/2021 14:14

Wanderer, there will be plenty on here that will question his credentials but strangely enough they don't question Bill Gates's credentials for giving health advice probably because the Fact checkers never question Bill Gates, funny that.

[emptyend] 16/4/2021 14:04

BBC REPORT:The discovery of a new Covid-19 variant in the UK, which was first identified in India, features two mutations that could be a cause for concern, an expert has said.Public Health England has reported that 73 cases of the B.1.617 variant have been confirmed in England, as well as four cases in Scotland.The new variant has been classified as a Variant Under Investigation by PHE.Prof Paul Hunter, a professor in medicine at the University of East Anglia, says the variant features two "escape mutations" - E484Q and L452R - that "are causing people to be concerned".He adds: "There's laboratory evidence that both of these are escape mutations."Basically, applying what we know about other human coronaviruses would suggest that this is going to be even less controlled by vaccine."But we don't know that for certain at the moment."

[wanderer1210_0] 16/4/2021 11:25

Watch the video by Dr Yeadon, no one can knock his credentials and explains everything that everyone can understand.

[geckotheglorious] 16/4/2021 11:15

Wanderer. That would be my concern too. I've already had Covid - lived in a house in close proximity with someone who also had Covid, as evidenced by symptoms and a positive PCR test result. I barely had the sniffles. :)

[wanderer1210_0] 16/4/2021 11:12

I would be horrified if I had to take a vaccine for something I have built immunity to. https://www.youtube.com/watch?v=aek74Lwe72s

[torquayfan] 16/4/2021 10:08

'Variants' - the Movie ! "SARS-CoV-2 variants are complicated: each one is made up of a collection of mutations, all of which have the potential to change the virus in unexpected ways. A Nature video explores what they might mean for the future of the pandemic." hTTps://youtu.be/B8UEZ9cfgz4

[torquayfan] 16/4/2021 09:40

Thanks EE. I found it curiously reassuring to hear a little current noise from our team.

[emptyend] 16/4/2021 09:15

New article in regional press today......https://www.expressandstar.com/news/Features/2021/04/16/west-midlands-at-the-forefront-in-the-fight-against-covid/QUOTE:In one of these schemes, Cobra is working with experts at Nottingham University on a 'universal' injection which could provide protection against all variants within a year.While the existing AstraZeneca and Moderna jabs target Covid's spike proteins, which are prone to mutate as they try to find ways of beating the immunity, the new jab will also target the core of the virus itself, which are less likely to change.Prof Lindy Durrant, of Nottingham University, says: "The chances both will mutate at the same time is unlikely. It doubles the chances you win over the virus."This means that it cannot only fight off all current mutations of the vaccine, it will only require minimal adjustment as new variants appear, giving the vaccine greater longevity.Professor Durrant, who is head of the university's spin-off company Scancell, says the next generation of vaccines needs to be better prepared to tackle the virus as it learns to evade the immune system."We have the advantage of learning from the inadequacies of the first generation of vaccines to make the second generation better," she says.Cobra is already producing batches of the Nottingham vaccine to test production and prepare for the trials.Business development director Alexandra Brownfield says the vaccine is "grown" inside cells in a bio-reactor. An 11-gallon 'soup' of cells and nutrients can produce "a few thousand doses" over four to six weeks.She says producing the first batch of vaccine is a thrill: "It's a really good feeling, but we are always thinking about the next batch."It's a high-pressure environment, so although it's a relief we're then thinking we've still got work to do with the next batch."Dr Cliff Holloway, chief executive of Scancell, says the Cobra team at Staffordshire is crucial to the development of the vaccine."Cobra has the expertise needed to produce clinical-grade plasmid at scale and we look forward to working with them to advance our vaccine and demonstrate its potential effectiveness," he says.

[oldnotwise] 16/4/2021 08:01

22.2/22.7495

[gooosed] 15/4/2021 21:21

Https://twitter.com/EricTopol/status/1382766397646729218?s=20

[inanaco] 15/4/2021 09:01

""The AstraZeneca vaccine had a greater effect – with 31% of people developing T-cells against the spike protein compared with 12% of those who had the Pfizer jab. People who had the AstraZeneca shot also had a stronger cellular response."" I think if Lindy achieved this, she would be horrified ......... Scancells target IMHO would be in the region of 90%

[torquayfan] 15/4/2021 08:37

Is this it Ivy ? https://www.theguardian.com/society/2021/apr/14/single-pfizer-or-astrazeneca-dose-produces-strong-antibody-response-study-shows? https://www.theguardian.com/society/2021/apr/14/single-pfizer-or-astrazeneca-dose-produces-strong-antibody-response-study-shows? When I copied the link, I trimmed it after the first '?' before posting. Showing off now - LOL

[emptyend] 15/4/2021 08:36

It varies with device. Some are perfectly fine. Others (especially in Thailand ;-)) seem trickier....

[oldnotwise] 15/4/2021 08:34

"Sausages" LOL

[miavoce] 15/4/2021 08:28

Hi Ivy, shame 'Thats Life' isn't still going - this would have made an amusing segment for Esther :-)

[ivyspivey] 15/4/2021 08:20

Hi Miavoce, I did try your suggestion but seems to vary depending on which device you post on. I have posted it on LSE and on here( even though it is not the actual link) so anyone better can repost if they want to. ATB

[miavoce] 15/4/2021 07:59

Using the app...(on android phone) hTTps://www.bbc.co.uk

[ivyspivey] 15/4/2021 07:44

I give up.