Synairgen Share Discussion Threads

[tidy 2] 25/3/2020 21:29

Watch this for the number of viruses SNG001 has been effective on so far. They have been waiting for a bout of virus effected patients to push on. hTTps://youtu.be/5DWOHyw-nAw

[bountyhunter] 25/3/2020 21:25

Agreed Dinga, well done Nobby, news proved to be fake and then repeatedly posted does more harm than good and is completely unnecessary. Synairgen are at the leading edge anyway.

Another one for the bin above?

[andymunchkin] 25/3/2020 21:23

hazl isAnother sheMale worstRamper on thepLanet

[andymunchkin] 25/3/2020 21:21

watchOoT inThe morning

[andymunchkin] 25/3/2020 21:21

sng wasRamped onMultiple threads & now theDump is goingTo be ugly

[andymunchkin] 25/3/2020 21:20

thoRot hasSet in tidy2Timing scmbag & co have sold bythe looksOfIt

[andymunchkin] 25/3/2020 21:19

inChina almostFinished

[andymunchkin] 25/3/2020 21:18

coronaVirus cycle aboutTo finish inUK

[andymunchkin] 25/3/2020 21:18

mostLikely

[andymunchkin] 25/3/2020 21:17

willTis sink back to 10p

[andymunchkin] 25/3/2020 21:17

rock subPenny now

[andymunchkin] 25/3/2020 21:17

tlou energy anotherBiting the dust

[andymunchkin] 25/3/2020 21:16

past pumpsBy tidy2 ukog now@ .35p down frm £11

[andymunchkin] 25/3/2020 21:15

tisWas pmpd by tidy pump&dumpCo ltd

[andymunchkin] 25/3/2020 21:14

tis was pmpd bylying cnt tidy2timer

[andymunchkin] 25/3/2020 21:11

placing@ pitiful 35p why???

[d1nga] 25/3/2020 20:05

Well done Nobby but the Tosspot will be back under a new account, so get ready for more nonsense

[belgrano2] 25/3/2020 20:02

For my six eggs, i expect word went around the brokers yesterday that they wanted a fast fund raising at an attractive price. stock price was buoyant and still rising swiftly.
Saw some insider trading at the end of yesterday and into today, when those that knew sold out knowig they could get twice as much stock for the same price..throw in some profit taking, and it dropped to 39p. Then realisation that those who wanted out have left and buying pressure lifted the stock into the close.

[nobbygnome] 25/3/2020 19:35

Sorry likya but I gave you a final warning yesterday. Various new rubbish today so you are gone....

[makendon] 25/3/2020 19:32

And this one posted this afternoon ....



Dr Cassandra Calabrese, a rheumatologist at the renowned Cleveland Clinic, said there is a ‘growing body of reports showing the benefit’ of the drug in COVID-19 patients.

The drug is still in development and goes by the name of SNG001.

Interferon beta-1b (IFN-beta) is a naturally occurring protein that orchestrates the body’s anti-viral responses.

SNG001 is a formulation of IFN-beta developed by Synairgen to prevent severe lower respiratory tract illness caused by cold and flu infections.

A different formulation using the protein is used to treat patients with multiple sclerosis (MS).

The drug called Extavia is self-injected every two days and works by slowing down the damage to the nervous system and by reducing the number of relapses.



Synairgen is a UK-based company, and it appears their formulation hasn’t crossed overseas yet.

But it does say has been approached by, and is in discussion with, a number of scientific and governmental bodies in the US and internationally since the COVID-19 outbreak began.



Laboratory studies have shown IFN-beta can protect cells from infection by a range of respiratory viruses.

These include the MERS and SARS coronavirus strains, leaving scientists expecting IFN-beta to also protect against the COVID-19 strain.

It has already been shown to improve the recovery of asthma and COPD (chronic obstructive pulmonary disease) patients who have other lung infections, such as flu.

Richard Marsden, CEO of Synairgen, said: ‘SNG001 has been well tolerated in clinical trials in over 200 respiratory patients to date and has accelerated lung function recovery in two Phase II asthma trials in patients with a cold or flu infection.’



SNG001 is inhaled with a nebuliser, which helps deliver drugs to the lungs.

Scientists believe it will prevent the coronavirus from taking over lung cells to replicate. This would prevent patients deteriorating until the point they need ventilation to survive.

Viruses, including coronaviruses, can evolve the ability to suppresses IFN-beta production in the body, thereby helping the virus evade.



Southampton researchers are conducting a Phase II SNG001 trial on COVID-19 patients to see if it could prevent worsening symptoms in those most at risk.

The trial, led by Professor Tom Wilkinson at University Hospital Southampton, will involve 100 patients at Southampton and up to ten other NHS hospitals.

Those patients will receive the best current COVID19 care, whilst inhaling either a placebo or SNG001 for 14 days.

[yet another final] 25/3/2020 19:32

The ROI is potentially astronomic cos the savings are in the 1000sIf it prevents a very ill person from needing ICU admission and subsequent ventilation......the saving is from not using those services, and the "icing on the cake" is that length of stay is reduced so frees up a bed for another patientIf the drug works, then it's use (indication) can be extended to mildly symptomatic patients, if it prevents deterioration and subsequent need for hospital admission...so more potential patients and more savings for nhs Btw if the drug works, the numbers add up and cost will not hold up regulatory approval (to complex to explain in terms of quality of life metrics etc, just accept it adds up)

[d1nga] 25/3/2020 19:24

If they gave me the chance of some at 35p I'd load up to the gunwhales too.