Quantabio Continues to Set Standard in PCR Performance, Stability and Sustainability with New Line of Eco-friendly Lyophilized Products
25 June 2024 - 1:04PM
Business Wire
New eQo 1-Step ToughMix kit features a
warm-start reverse transcriptase in a single-tube master mix format
that is conveniently shipped, stored and set up at room
temperature
Quantabio, a leading provider of robust DNA and RNA
amplification reagents for the most demanding molecular testing and
life science research applications, today announced the launch of
the eQo 1-Step ToughMix kit, the first product from its
third-generation line of advanced reagents for highly sensitive and
reproducible PCR and qPCR applications. The new eQo (pronounced
“eco”) product line comes in a lyophilized, bead-based, and
eco-friendly format that is conveniently shipped, stored and set up
at ambient temperature. This eliminates the need for dry ice,
significantly reducing the shipping footprint and its harmful
impact on the environment.
“The new eQo product line is the culmination of years of
research and development and ongoing commitment to delivering
innovative, high-performing products that reduce our carbon
footprint and improve sustainability,” said David Schuster, Head of
R&D at Quantabio. “The new kit includes the latest ToughMix
chemistry that further enhances assay sensitivity and performance,
all in a more convenient and environmentally friendly package. Our
customers can now break the cold chain and eliminate all of the
costs and logistical challenges associated with dry ice.”
Featuring the company’s latest advances in ToughMix chemistry,
enzyme engineering and formulation optimization, the eQo 1-Step
ToughMix was designed to deliver superior assay performance for a
wide range of challenging starting materials with common PCR
inhibitors. Compared to currently available products, the new kit
is capable of supporting five-plex assays and has consistently
demonstrated improved yields with higher amplification rates and
lower quantification cycle values for a variety of RNA assays. When
used with a multiplexed COVID/flu assay, eQo 1-Step ToughMix was
able to detect down to two copies of virus, evidenced by a strong
amplification signal, resulting in up to a 10-fold increase
compared to other premium 1-Step kits. The ability to reliably make
a positive call at such low copy numbers is a key differentiator of
the new kit’s technology and chemistry combination.
The eQo 1-Step ToughMix kit was designed to improve the user
experience with a simple workflow that accelerates project
turnaround times. New enzymes and chemistry enable specific and
efficient conversion of even highly structured RNAs at temperatures
between 55 degrees and 60 degrees Celsius. The highly processive
and novel warm-start reverse transcriptase allows scientists to run
qPCR and PCR experiments without ice either right on the bench or
out in the field. Once the lyophilized eQo beads are rehydrated,
the 4x concentrated master mix is stable for one year at -20
degrees Celsius. The kit was created to withstand multiple freeze
and thaw cycles, and the single-tube format facilitates easy
reaction setup and prevents potential cross-contamination. The
compact and recyclable package can be shipped and stored for up to
one year at room temperature.
“The sensitivity, scalability and sustainability of the new eQo
1-Step ToughMix makes it ideal for broad use, both in research and
applied markets, and in the laboratory or in the field,” said
Heather Meehan, PhD, General Manager of Quantabio. “With our eQo
product line, Quantabio offers our customers the flexibility to use
our beads as a bulk master mix or as a customized formulation
dispensed in a single bead configuration.”
Quantabio offers the eQo 1-Step ToughMix reagents in two
packaging configurations of 100 and 1,000 reactions. In the future,
the company will add additional eQo products that can be customized
for customers looking to create their own assays. For more
information on the eQo technology, please visit
https://www.quantabio.com/eqo-technology. For more information on
the new eQo 1-Step ToughMix, please visit
https://www.quantabio.com/product/eqo-1-step-toughmix/.
Live Webinar Quantabio is hosting a webinar to share
application data and provide additional details about how the eQo
1-Step ToughMix can help laboratories enhance their RNA
workflows.
Merging high performance with sustainable design: Introducing
eQo 1-Step ToughMix, a lyophilized solution for demanding RNA
quantification applications
Date and time: Tuesday, June 25th at
11 am – 12 pm ET Registration: please click here.
About Quantabio Quantabio is a leading provider of
advanced DNA and RNA amplification reagents for the most demanding
molecular testing applications in applied, translational and life
science research. For the past 20 years, the Quantabio team has
been developing pioneering amplification technologies to deliver
cutting-edge products to researchers focused on critical PCR, qPCR
and next-generation sequencing (NGS) based applications. Based in
Beverly, Mass., Quantabio offers a growing portfolio of products
through its international sales operations, as well as a global
network of distributors and commercial service providers. For more
information, please visit www.quantabio.com.
Quantabio products are intended for molecular biology
applications. This product is not intended for the diagnosis,
prevention or treatment of a disease.
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