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Share Name Share Symbol Market Type Share ISIN Share Description
Oxford Biomedica LSE:OXB London Ordinary Share GB00BDFBVT43 ORD 50P
  Price Change % Change Share Price Shares Traded Last Trade
  +15.90p +2.34% 696.00p 61,771 16:35:00
Bid Price Offer Price High Price Low Price Open Price
685.00p 695.00p 699.00p 648.00p 680.00p
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Pharmaceuticals & Biotechnology 37.59 -11.76 -0.29 459.6

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Date Time Title Posts
23/1/201919:41Feck off the_doctor2,902
23/1/201909:09Oxford Biomedica Bulls Only Thread30,913
23/1/201907:31Oxford Biomedica1,000
05/11/201817:18Oxford Biomedica - the_doctor free thread341
05/11/201817:17The hypocrites thread75

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Oxford Biomedica (OXB) Most Recent Trades

Trade Time Trade Price Trade Size Trade Value Trade Type
2019-01-23 17:27:45680.148655,883.21O
2019-01-23 17:15:00670.004,99633,473.20O
2019-01-23 17:15:00654.007,19547,055.30O
2019-01-23 17:15:00654.163,62223,693.68O
2019-01-23 17:13:55694.781,50010,421.64O
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Oxford Biomedica (OXB) Top Chat Posts

DateSubject
23/1/2019
08:20
Oxford Biomedica Daily Update: Oxford Biomedica is listed in the Pharmaceuticals & Biotechnology sector of the London Stock Exchange with ticker OXB. The last closing price for Oxford Biomedica was 680.10p.
Oxford Biomedica has a 4 week average price of 603.70p and a 12 week average price of 603.70p.
The 1 year high share price is 1,062.60p while the 1 year low share price is currently 487.50p.
There are currently 66,039,775 shares in issue and the average daily traded volume is 92,527 shares. The market capitalisation of Oxford Biomedica is £459,636,834.
15/11/2018
22:38
marcusl2: HTTps://youtu.be/PhTbzc-BqKs?t=1292 (OXB share price next year)
05/10/2018
08:58
stocktastic: If OXB values its stake at $4m, then the company valuation will be $500m Will be interesting to see how Orchard prices. I feel OXB likely undervalued and the IPO cap will be $750-1000m That will give OXB a further valuation gain So, reading the RNS today OXB gets a low single digit royalty from Orchard I had assumed 1% below My view was that Orchard is worth about 30p on the current share price. That still seems in line with what we know about the deal and Orchard. That said, if OXB doesn't take part in the IPO, then it will see its stake further diluted. I have always said that posters get over-excited about Orchard and ramp up its possible contribution (actual contribution even lower) to the valuation. I wonder whether the Orchard backers will be offloading any stock in the IPO, or as they suggest, using the proceeds for development I was amazed to see how much Orchard spent last year - clearly they're really driving things forward, which is what they need to do and why they need the IPO to fund it further. --------------- stocktastic - 15 Aug 2018 - 18:29:54 - 30773 of 30805 Oxford Biomedica Bulls Only Thread - OXB From what I can tell, OXB has a 0.8% stake in Orchard and at this recent fundraiser, the company was valued at $750m Allowing for the fundraiser being at a discount, you could perhaps say the company is valued at $1000m OXB's stake would therefore be worth say $8m presently If Orchard performs as hoped with trials (data certainly look good in several cases and it's ex-vivo, reducing safety risk), then OXB's stake would be worth $15m NPV, growing to $30m over time. Clearly that's a way off and carries risk I would estimate OXB to be in line for $50m royalties NPV if all of the trials succeeded, assuming in line with Orchard's planned base scenario. That figure would grow to be worth $100m over the passing of time. At present, I'd say that OXB stands to have a total of $6m present share value and $20m NPV of the royalty stream if 1% royalty is appropriate. Clearly double that if it's 2% etc. = ~30p on the share price for Orchard, presently (ie. risk-adjusted) All IMO
16/7/2018
10:25
stocktastic: Looks like the drop is forcing some on the other thread to wise up 'I am aware (via those links) that there are better mousetraps in development which may (or may not) be eating into OXB's business in 5 years time' Amusing really that said poster was made aware of those 'potentially' better mousetraps by my posts, yet blindly attacked them. What gets me most though, is that this poster refers to the risk in say 5 years' time and how he cannot make a call on things that far out (fine). But, the point missed my many is that the OXB share price has been pricing in a huge amount of success for more like 10 years out!
10/7/2018
21:14
beanol: This is a bit about Oxb from a current Vulpes pitch document just out to potential new investors into its Vulpes Life Sciences Fund. Apologies the slides have come out so poorly:Oxford BioMedica (OXB)Company OverviewThe company has 3 exciting gene therapeutic areas: • Parkinson's• Cancer• OcularAchievements• Exclusive Licence agreement for OXB-102 to treat Parkinson's Disease with Axovant Sciences • FDA approval for CAR-T manufacturing• Lentivector platform technology is a proven success• Third party manufacturing for Novartis proves it is a leader in CAR–TBoard Representation OwnershipDate of Investment• Third party manufacturing deal with Sanofi in haemophilia Martin Diggle - Board member since 2012One of the world's most experienced gene therapy companies.The company has unrivalled gene therapy drug, technology and manufacturing capabilities.17.7 % - LSE Main Board CompanyThe Diggle family have been invested since 2001Vulpes Investment Management Private Limited CONFIDENTIAL13 Vulpes Value Creation: OXB Vulpes joined the board in 2012. The share price has increased around 500% since this time*  Provided debt-financing to help fund the company's transition in 2013/14Pushed for and achieved senior executive upgrades in critical areasHelped the company attract new equity investorsProtected existing equity investors from onerous dilutionHelped guide the company to focus on reduction of burn and on cash generativemanufacturing processes* As of 30h June 2018Vulpes Investment Management Private Limited CONFIDENTIALOXB Deals: AxovantOXB has granted an exclusive global licence to US biotech company Axovant Sciences to develop and commercialise OXB's proprietary gene therapy drug for Parkinson's DiseaseThe deal is worth up to $842.5 million. OXB will receive a $30 million up front fee and $55 million in development milestones over the coming three yearsOXB stands to receive between 7-10% tiered royalties for the renamed drug AXO-LENTI-PD in a market that is potentially worth several billion dollars a yearAxovant has over $200 million on balance sheet, backed by parent, Roivant, with new management. Axovant has recapitalised after previous turbulence due to an Alzheimer drug trial failureThe deal proves OXB's business model, to extract tangible value from the synergies between its lentivector platform and proprietary product divisionsThe AXO-LENTI-PD deal with Axovant crystallises the value in the product business of OXB and simultaneously opens further platform opportunities such as product supply of AXO-LENTI- PD to Axovant if the drug is approvedVulpes Investment Management Private Limited CONFIDENTIAL15OXB Deals: Treating Parkinson's DiseaseParkinson's Disease is one of the most common neurological disorders. The global prevalence is projected to grow to 2.89 million cases by 2020, up 30% from todayParkinson's affects mainly the elderly. Today 8.5% of the global population are over 65 and this will rise to 17% by 2050The direct and indirect costs of Parkinson's in the US are estimated at $25 billion annuallyThe disease is highly debilitating and affects predominately dopamine-producing neurons in a specific area of the brain called substantia nigra leading to cognitive impairment, tremors and balance problems. Currently, all therapies only improve symptoms without slowing or halting disease progressionAdministration of L-DOPA to boost the loss of the dopamine helps but dosing is a major problem with peaks and troughs. As the disease progresses and neurons continue to be lost, these medications become less effective while at the same time they produce a complication marked by involuntary movementsOXB has recently made a dramatic breakthrough by engineering a virus to carry genes responsible for synthesising dopamine which can be injected into the substantia nigra and produce a stable supply of dopamine. This involves a single operation and patients show dramatic improvements which have currently lasted for five years with no signs of decreased effectiveness This is a game changer and will drastically improve the quality of life for Parkinson's patients and greatly reduce the personal, social and medical costsVulpes Investment Management Private Limited CONFIDENTIAL
13/4/2018
20:58
beanol: It really is getting boring Pram. For example the idea that Oxb Directors buying shares in the way they have been doing recently is going to help boost the Oxb share price in the short term is almost certainly for the birds. The last time they did this was to help support the share price when (in retrospect) no good news was in prospect. And the share price fell significantly over a long period of time. Much better i suggest to consider the Doc as a contributor whose posts are sometimes much needed if unwelcome but that some go over the top and need correcting. For example Doc's attacks on Marcus and Harry are often just out of order and some of us call them out. But for f's sake just leave some of your bad ill tempered irrelevant postings out. That is not to say that we and I in particular don't value most of your posts. They are largely flipping great. And your connectivity to the senior management of Oxb often gives us insights that would otherwise be denied us.
22/2/2018
13:14
luxsuspick: Breaking Down Oxford BioMedica PLC’s (LON:OXB) Ownership Structure Erna Eldridge February 22, 2018 I am going to take a deep dive into Oxford BioMedica PLC’s (LSE:OXB) most recent ownership structure, not a frequent subject of discussion among individual investors. Ownership structure has been found to have an impact on shareholder returns in both short- and long-term. Differences in ownership structure of companies can have a profound effect on how management’s incentives are aligned with shareholder returns, and whether they adhere to corporate governance best practices. Although this is an important factor for long-term investors, many investors can also be impacted by institutional presence and their high-volume trading. Therefore, I will take a look at OXB’s shareholders in more detail. Check out our latest analysis for Oxford BioMedica LSE:OXB Ownership_summary Feb 22nd 18 LSE:OXB Ownership_summary Feb 22nd 18 Institutional Ownership OXB’s 68.26% institutional ownership seems enough to cause large share price movements in the case of significant share sell-off or acquisitions by institutions, particularly when there is a low level of public shares available on the market to trade. These moves, at least in the short-term, are generally observed in an institutional ownership mix comprising of active stock pickers, in particular levered hedge funds, which can cause large price swings. With hedge funds holding a 18.72% stake in the company, its share price can experience heightened volatility. But I also examine other ownership types and their potential impact on OXB’s investment case. Insider Ownership Insiders form another group of important ownership types as they manage the company’s operations and decide the best use of capital. Insider ownership has been linked to better alignment between management and shareholders. Although individuals in OXB hold only a 3.79% stake, it’s a good sign for shareholders as the company’s executives and directors have their incentives directly linked to the company’s performance. In addition to this, it may be interesting to look at insider buying and selling activities. Keep in mind that buying may be sign of upbeat future expectations, but selling doesn’t necessarily mean the opposite as the insiders might just be doing it out of their personal financial needs. LSE:OXB Insider_trading Feb 22nd 18 LSE:OXB Insider_trading Feb 22nd 18 General Public Ownership With 6.23% ownership, the general public are also an important ownership class in OXB. This size of ownership, while considerably large for a public company, may not be enough to change company policy if the decision is not in sync with other large shareholders. Private Company Ownership Another group of owners that a potential investor in OXB should consider are private companies, with a stake of 2.82%. While they invest more often due to strategic interests, an investment can also be driven by capital gains through share price appreciation. However, an ownership of this size may be relatively insignificant, meaning that these shareholders may not have the potential to influence OXB’s business strategy. Thus, investors not need worry too much about the consequences of these holdings. Next Steps: I suggest investors seek some degree of margin of safety due to high institutional ownership in OXB, in particular due to the strong presence of active hedge fund investors. This may enable shareholders to comfortably invest in the company and avoid getting trapped in a sustained sell-off that is often observed in stocks with this level of institutional participation. However, if you are building an investment case for OXB, ownership structure alone should not dictate your decision to buy or sell the stock. Instead, you should be evaluating company-specific factors such as Oxford BioMedica’s past track record and financial health. I highly recommend you to complete your research by taking a look at the following: 1. Future Outlook: What are well-informed industry analysts predicting for OXB’s future growth? Take a look at our free research report of analyst consensus for OXB’s outlook. 2. Past Track Record: Has OXB been consistently performing well irrespective of the ups and downs in the market? Go into more detail in the past performance analysis and take a look at the free visual representations of OXB’s historicals for more clarity. 3. Other High-Performing Stocks: Are there other stocks that provide better prospects with proven track records? Explore our free list of these great stocks here. NB: Figures in this article are calculated using data from the last twelve months, which refer to the 12-month period ending on the last date of the month the financial statement is dated. This may not be consistent with full year annual report figures. Want to know why the market is moving
14/2/2018
15:57
old sage: Gareth Jones Don't know if there's ever a good time , to be a LTH (unless you got into OXB at circa 3 pence and are holding on for 30 pence. However with the future looking promising, anyone with an interest in OXB should, (as HST alluded to, earlier ) hang on in there. The prospects have never been better for the OXB share price, over the last two decades. GLA
05/12/2017
17:49
scrutable: There is such a dog fight over clinical details and egos on this board, that non technical people must have lost sight of the fundamentals which affect the OXB share price. It has exhibited an ever more dampened sideways oscillation and fails to reflect the great furore over the prospects for CAR-T therapy repeated in the global Press, Conferences and video broadcasting, since July. I am irritated by failing to be able to turn up an influential article in the European edition of the NY Times, quoting JD several times and OXB by name that I read a week or so ago. The gist was that authorisation to manufacture the virus vector in cell therapy is excrutiatingly difficult to earn, and that there is a currently irremediable shortage of the product putting OXB in a lead position with more potential drug developer clients than can be supplied for years. Only this can explain the fairly unusual contract they were able to close with Novartis. Would be purchasers are jostling each other for access to the few adequately structured suppliers Most of those who have tried to establish an in-house supply have wasted years and failed. One such company acquired a recipe and IP, but after 18 months had failed to produce anything at all of use due to a very small error controlling the exact acidity of the supply, which was killing the viral vector. There is no short cut to displacing OXB as a main supplier. The technology and process detail, and the control procedures, the staff trained and trusted to apply them, agreement details and signatures required cannot be established in under 2-3 years. So why have investors failed to take the basics of supply and demand into consideration.
13/9/2017
09:33
graham101: Thanks for the replies. I realise that the share price has gone up dramatically in the last year. However, when the Novartis FDA approval came through, I would have expected OXB share price to go even higher, which is why I bought in. It has dropped back quite a bit since then and that is what I can't understand. The other reason I bought is because I think the future use for the treatments is astounding if all goes to plan. Fortunately, I bought some KITE two weeks before the GILD take-over was announced so had a great return in a very short time. Just luck though. I really hope these treatments are successful as it could transform so many lives.
05/9/2017
12:08
prambigear: This news is not helping the Novartis or OXB share prices, it should because it lengthens the time where we have the market, but I guess investors do not know the difference between our CAR-T treatment and an allogeneic CAR-T. the_doctor does. But presumably he is doing something else....
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