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OXB Oxford Biomedica Plc

419.50
-7.00 (-1.64%)
Last Updated: 12:56:57
Delayed by 15 minutes
Share Name Share Symbol Market Stock Type
Oxford Biomedica Plc OXB London Ordinary Share
  Price Change Price Change % Share Price Last Trade
-7.00 -1.64% 419.50 12:56:57
Open Price Low Price High Price Close Price Previous Close
423.00 419.00 427.00 426.50
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Industry Sector
PHARMACEUTICALS & BIOTECHNOLOGY

Oxford Biomedica OXB Dividends History

No dividends issued between 23 Dec 2014 and 23 Dec 2024

Top Dividend Posts

Top Posts
Posted at 16/12/2024 20:39 by harry s truman
Xoptimist,

I think it depends on how you value the company, which I appreciate is stating the obvious.

We do know that the "average" CDMO should trade on more than 5x sales and an average CDMO isn't one which owns the patents on the LentiVector which is key to one approved treatment and a whole bunch in late trials.

What do we currently trade on with our market cap today of c£450m? A little over 3x. What if Novo simply accept that OXB is worth a lot more than its market cap and realise that there are enough shares in very few hands to stop a cheap bid - which has never happened during much worse times?

Today Samsung Bio (a very specialised CDMO) trades on 16.29x sales and nobody complains.

In a couple of weeks we go into a year where Frank said the sales would be better than +35% on this year. That basically means £180m but it might be better.

What if our major shareholders say that they want a bid premium on top of a fair valuation which the market price doesn't reflect?

I'd agree wholeheartedly that we would be in the hands of others, but I seem to remember that 13 holders have 70% of OXB. Admittedly one of those is Novo with 12% but most of the others against and it's still no - which is (I suspect) what kept the p/e wolves from our door when things were much worse.

5.5x 2025 sales is probably £10 per share and what if our major shareholders say they aren't prepared to sell for sector average and want compensating with a better valuation and bid premium?

I of course don't know and don't pretend to.

I agree with Dom's point in that Novo are in the happy position of being able to bid billions without visiting a bank for a loan or visiting a city firm for a placing / fundraising, so where would the leak come from?

Mentioned here before that I have no evidence other than circumstantial, but:-

The Novo Holdings boss has said they will buy specially selected bio service companies (like OXB which they already thought worth buying 12% of).

OXB has been extremely quiet and for the first time I can remember not a single insider has bought a share in the year (since Novo bid for Catalent).

Yes Catalent shareholders overwhelming accepted a low bid premium from Novo but they also knew that they were on a sticky wicket without Novo's money - which does sort of beg the question of how Novo plan to make a business success of that other than by simply throwing more money at it?

There are two sides to this, but let's forget about Catalent for a minute and say that Novo harboured desires of entering the Cell and Gene Therapy sector via OXB, then how do they make that work for them better than it has worked / is working for OXB? Surely the answer is simply scale, and on a scale which OXB wouldn't be able to afford alone anytime soon?

Flip back to Catalent and (if you believe the official version) then Novo only wanted Catalent for the 3 pen injectable sites which solve a supply shortage for their mega-selling weight loss drug.

Why didn't Novo just bid this notional $11bn for the 3 factories they wanted in a simple transaction / trade sale which happens a lot in the pharma industry and save themselves a lot of trouble?

I think there are two possible answers to that, with one being that Catalent said a firm no to them cherry picking, making it all or northing, or...

Novo thought, 2 birds with one stone - we buy the lot, sell the pen injectables to Nordisk then merge OXB with the Catalent C&GT / C&GT capable plants. Maybe the rest they will keep to run as a big CDMO or plan to slowly sell off the individual sites as and when that makes good business sense.

So yes I am guessing, but there is some supporting evidence behind it - even though it is circumstantial.

If Novo Holdings are keen to diversify into CDMO and are sold on those future forecasts for C&GT CDMO market size, then there is some logic in the business case here.
Posted at 07/12/2024 16:38 by harry s truman
Aside from the obvious you mean?

IM merged ABL Europe into OXB to get a part of future business which they couldn't compete for alone via a shareholding in OXB which they took as full payment.

Amazing deal for OXB but driven by what OXB had and what ABL didn't have. As Seb explained, they would never have been able to catch up with the vector tech on their own and when the analyst asked "so it was a case of if you can't beat them join them?" he replied yes.

Would they have imagined OXB then being bought out? Well it must have been considered as a risk.

If it's enough money to compensate them for selling those expected future OXB profits now then I would imagine they would be ok with it. If not then what are they going to do? It's a risk we all take.

If there is no bid coming then I would expect them to be very pleased with c£180m in sales next year and a profit (as will I).

Something is going on and your guess is as good as mine. OXB went quiet 6 months before the ABL deal was announced and no insiders bought shares between the full year results and that deal announcement (following which a lot of them immediately bought shares).

Nobody could have guessed that deal was on from what was in the public domain before it happened. Investment detectives might have spotted that Seb was an adviser to IM, but how would you guess more beforehand?

Today is a bit different as there seem to be a lot of clues out there indicating that Novo could make good use of OXB's skillset in their newly acquired C&GT arm of Catalent.

Is it true or is it just coincidence?

As I wrote the other day, if there is something in this then following FTC approval there is no point in Novo waiting. They have just spent 16.5bn on something which they will want to see come good.

Next step is waiting to see what the FTC say.
Posted at 06/12/2024 20:35 by harry s truman
Jez,

I think the grand unifying answer to that one is the oft used "it is what it is".

I've noted more than a few times that my ideal scenario is for OXB to to remain single and become a dominant player in C&GT CDMO. I would very much like it to become a British success story, even though Frank has dropped the Oxford link in the company name already.

How many people sold at the top and bought at the bottom? I would have thought it's not most of us. I certainly bought every time I thought it was the bottom from £7 down to under £2, but I'm not sure that counts as timing it right.

If my guess here is correct - and remember it is just a guess based upon a large bag of clues which individually might not be that compelling - then for Frank to grow OXB to another 5 locations internationally is an amount of time and money which is probably not within his realistic remaining time at OXB given his age.

Conversely, for Novo to give Catalent a bag of cash to develop the world's best / equal best LentiVector, all the supporting tech and process improvements + a similar but more recent AAV, well that literally could take 20 years.

To me there's an obvious threesome where OXB's knowledge marries Catalent's capacity and Novo's money, giving "the" C&GT CDMO in a timescale which none could achieve without the other two.

If I'm correct then the FTC will soon say yes because Catalent was in a bit of a pickle going forwards without Novo's money. Novo (in this scenario) would want OXB quickly and without resistance from the big holders (we don't really count).

I think in a bid scenario the minimum price has to be what Serum paid for their 3% else they immediately alienate one large holder.

The other issue is IM (who of course own 10%) and it's pretty much impossible to work out what IM actually paid for their shares as they gave us a very good business for next to nothing and let us pay with shares which were an artificially high price. They didn't do that in a fit of altruism, they did to be part of the the future number 1 C&GT CDMO. If Novo bid low then not only have they had that future plan rug pulled from under them, but they have also been robbed in the process. QED IM will want a lot of money to compensate them. Happily Novo have a lot of money.

I suppose the bottom line here is how important this future part of their CDMO empire (the C&GT part) is in Novo's plan. We have seen other companies in our sector bought for 10x and 16x sales when they weren't even profitable - they simply had something the bidder wanted.

We are 3 working weeks away from OXB starting their return to profit.

-----------

jezmundo 6 Dec '24 - 13:10 - 9342 of 9348

H. Your theory on an impending takeover is compelling but to me personally very undesirable. Having like most of us, sold most of my stock during the covid fiasco, re entering when the price had tanked, a takeover of lets say 10 - 15 pound would be at best disappointing
Posted at 05/12/2024 10:23 by harry s truman
Super,

I'm sure you must have picked up on it by now, but I've 99% convinced myself that OXB's effective closed period since our major shareholder bid for Catalent (who have a business division which fits nicely with OXB's business) isn't a coincidence.

It of course could turn out to be just that, but I don't think it is. I've thought about this for a long time now and tried to work out what else it might be (malaria and such) but I think that by far the best fit (on information we have) is Novo and I'm expecting something to happen following the EU/FTC decisions on the Catalent bid (the EU decision due by tomorrow night).

Novo seem to want to diversify away from the diabetes business which has made them their billions and CDMO ("selling expertise to others") seems eminently sensible to me. They have to do it on a huge scale else it's pointless for them (what use is a £40m profit to a company with £150bn in assets?).

If they want the world's biggest or equal biggest CDMO then buying the previously struggling Catalent for $16.5bn is a good start.

Assuming the regulators say yes then my best guess is that Novo will make a very friendly offer to OXB which Frank will recommend to us. That will go very quickly as Novo have no need to visit banks or the markets and after we all accept then Frank will be asked to roll out OXB into the 4 Catalent C&GT sites + the empty VMIC site at Oxford.

From then on OXB Catalent "a Novo Holdings company" will not only have all the "firsts" but will also be the biggest in C&GT CDMO. Frank will be back in charge of a private company and with the support Novo will offer I expect them to do very well.

As I've said a lot, just the way I see it at the moment, but it all seems to fit very nicely and if we are all still OXB shareholders this time next year then I won't be disappointed but I will be surprised.
Posted at 04/12/2024 10:17 by harry s truman
2 days to the deadline for the EU anti-trust decision on Novo Catalent.

Meanwhile Novo on a charm offensive with Catalent's existing US customers, offering them contract extensions by way of reassurance.

The US FTC decision is supposed to be before the end of the year.

Catalent seem very happy to be taken over and have their recent wobbles rendered irrelevant by Novo's very deep pockets.

Catalent's shareholders 99% in favour rather than the other option of Catalent staying single.

Novo is reassuring Catalent's customers.

US stock market seems to think that the deal will go through at the offered price, which to me is a reminder of the bookies all knowing Trump would win whilst the world's press were busy thinking up reasons of why he wouldn't.

Personally (usual wealth warnings here / amateur forecasting alert) I think the deal will pass both regulators without issue.

Shortly after that Novo Holdings will sell 3 factories to Novo Nordisk and become owner managers of the rest (a very large global CDMO which needs a boost).

If that happens then we soon (relative term) will find out if there is a connection between Novo Holdings owning 12% of OXB and not a single OXB insider buying shares since Novo Holdings bid for Catalent.

As mentioned previously many times, there's perhaps a healthy dose here of me connecting random events which look connected but are just circumstantial.

However, it does make sense to me that if Novo Holdings are looking to make Catalent a core asset (and they are) then they can't just leave it as is. There must be a plan (which is always easier to come up with when sat on a cash mountain).

The Novo Holdings non-exec director on our board will know much better than us what OXB can do. But he will also know that for OXB to grow (even at better than 35%) will take years because that's how long it takes to fund and kit out new facilities.

Money isn't an issue for NH (unless having too much of it is a problem) but in weeks they are likely to own 4 cell & gene therapy factories and a blank canvas of the brand new and empty former UK government Vaccine Manufacturing & Innovation Centre (VMIC) in Oxford, on OXB's doorstep.

I couldn't give you the odds here of this coming true, but if following Catalent approval Novo Holdings bid for the 88% of OXB which they don't own, then something which would have taken OXB 20 years or longer, can be done very quickly.

Novo could roll out OXB's tech / knowhow and experience into the existing 4 Catalent C&GT factories, whilst OXB get a 6th site at Oxford to expand into.

OXB shareholders get paid off on acceptable terms which Frank will recommend. In exchange for that money Novo Holdings quickly own the biggest / best C&GT CDMO.

Stranger things have happened at Christmas.
Posted at 24/11/2024 21:04 by harry s truman
takeiteasy,

I'm guessing and it's nothing more than a theory which seems to me to fit quite well.

Remember the only real news OXB have given us this year has been the upward revision of the guidance for FY25 and then news that we will be making a multiple myeloma CAR-T vector for somebody soon. Odds are that the next OXB news will be more detail on that.

However, in the background here we have OXB's silent running and the possible simple coincidence that no OXB insiders have bought shares since Novo Holdings (the major OXB shareholder) bid for Catalent (huge CDMO which has a 4 / 5 plant C&GT division).

My guess here is that Novo (who officially are only buying 50 location Catalent to get 3 sites to sell to Nordisk for their weight loss drugs) have a little side plan here to combine OXB with the Catalent C&GT division. It would roll out OXB's industry leading tech (I realise I'm biased as a holder but it is) into a capacity / capability which would be unaffordable for us near term, but for Novo could potentially give them a lion's share of a market forecast for C&GT which is huge.

So what are the possibilities?

1) it's a complete coincidence and means nothing.

2) it's related to the Novo Holdings boss saying that they intend to use their windfall from the weight loss drugs to buy up speciality service companies.

3) it's something else.

What are the answers? (aka my guesses)

1) nothing will happen with Novo and we will move into our return to profit in 2025 with a great year for shareholders.

2) Novo will make an offer for OXB (likely a friendly offer to placate IM and Serum) and create the No.1 C&GT CDMO in the world. With OXB's expertise, Novo's money and Catalent's waiting capacity then that's definitely on the cards there if they want to do it.

3) Could be something other than an offer for all of OXB but still linking the businesses.

We will see in time, but Novo and Catalent both see this as being cleared before the end of the year and if there is a plan involving OXB subject to that approval then what would be the point in waiting?
Posted at 22/11/2024 10:11 by harry s truman
Slight dose of melancholy this morning for me because, as those with long service badges might remember, first days of 2024 I wrote that my sole 2024 OXB target was for them to get back into the FTSE250.

Today (well close of play today if we are being picky) marks the 4th and final FTSE review of the year and quite obviously we haven't. I can't help but think that there have been a few opportunities during the year where much better IR/PR (or even some visible IR/PR) could have perhaps swung it for us, but unfortunately OXB can't / won't talk about that side of the business these days or doesn't see the point.

Anyway, onward and upward as someone once said, and I'm guessing that 4 weeks today is the end of the 2024 trading year in all but name and after the break we start our long awaited profitable year and finally return from the naughty step.

I'm sure most of you will have worked it out by now, but for the first time holding OXB (and unlike Del Boy) I don't see a "this time next year" for us as OXB shareholders.

I think Novo have eyes now firmly set on that prize of the forecast C&GT CDMO market and see OXB's "tech, knowhow and proven ability to expand" + Catalent's enormous waiting capacity as the route to that very big prize.

Yes it might be wishful thinking based upon a lot of news stories and circumstantial evidence all stuck together to come up with a case, but remember my honest preference would be to hold OXB as it becomes "the" pure C&GT CDMO with that 20%+ EBITDA margin in 2026 forecast looking very nice indeed.

But I think Novo have the same idea now (albeit on steroids). It gets rid of some of their enormous cash pile. Utilises the parts of Catalent which Novo have made no attempt to explain the attraction of. Gets them a premium slice of the gene delivery market + everything else OXB can do. Perhaps most importantly though, it would get Novo another huge income stream which was relatively risk free once mature, as of course it's the partners / customers who are taking the development risk - Novo would simply be charging handsomely for helping them with a service.

EU decide on approving the Novo Catalent purchase by 2 weeks today.
Posted at 08/11/2024 16:32 by xoptimist
Greetings everybody. I am sure many of you will have clocked that Avid Bioservices was bought this week by a couple of large specialist healthcare private equity funds including the UK’s GHO. I am guessing you will have discussed this but I cant see any posts. Perhaps this got lost in the US election results on Wednesday.

I know many of you shot me down last time when I suggested that Avid was one of our better CDMO comparables – albeit operating in a slightly different space in antibodies.

However close you think it is to being a comparable I think it is nevertheless worth noting that Avid was sold for $1.1bn (£851m) – a 22% premium to market - or 6.8 times multiple of their forward guidance for FY2025 sales of $160-164m –17% growth rate over FY2024 (about half compared to our current estimated 3 year CAGR of 35%).

If Avid is a decent industry comparable then OXB on similar multiples would be worth £884m today (or £8,35 a share). (I have used Frank’s 2024 revenue guidance as Avid is already halfway through their FY2025 but of course there would be a case for OXB being valued on its forward revenue estimate of £175m of revenue for 2025).

Avid is in the larger antibody market and therefore carries a lower risk profile than OXB but this market generally has lower margins; more competition and lower barriers to entry. On the other hand, Avid is narrowly profitable, which is obviously a valuation plus.

Whilst many of you will intelligently argue that OXB is unique with much superior competitive advantage and R&D depth and knowledge (creating some kind of a moat) – nevertheless I would happily take 6.8 times sales this year and next (£1,19bn on FY2025 sales of £175m or £11,23 a share).

And if OXB is really so unique and superior and deserves a higher multiple than Avid’s 6.8 then hallelujah to that!

Sadly, we are a long way away from these valuation levels with OXB currently trading with a market cap of about £440m ($568m) or about half the valuation the PE guys have put on Avid. And we are trading at 3.4 times our 2024 estimated revenue and 2.5 times 2025 est.

If Novo does emerge as a potential buyer at least the Avid deal might establish a minimum benchmark – although perhaps there are other PE firms that can see that taking OXB private could unlock much greater value. In any event hopefully soon we will start to close what is a clear valuation gap with increasing benchmarks and comparables.
Posted at 05/11/2024 15:03 by harry s truman
The Eurovision side of this always makes me smile. Anyway, back to OXB.

OXB presented recently in Rome at the European Society of Cell & Gene Therapy 2024 conference.

You'd never guess unless you looked for it, but the relevant poster they presented is hidden on the OXB website here

Crucial part to note here for those of us interested in OXB are the terms SAN & M-SAN.

"Our findings demonstrate that the use of SAN and M-SAN exhibited superior activity under typical LV manufacturing conditions.".

SAN is Salt Active Nucleases and it's the technology of ArcticZymes where our CEO Frank is the new Chairman and I understand from today's internet trawl that OXB are the first to try it.



”M-SAN demonstrated superior performance compared to the Industry Standard Nuclease when integrated into OXB’s LV production process”

"SAN also outperformed the Industry Standard Nuclease when integrated into OXB’s LV production”

“Over 10-fold reduction in residual DNA compared to the Industry Standard Nuclease”
Posted at 24/9/2024 20:49 by mirabeau
If anyone's interested below is OXB's earnings call transcript with the management and analysts asking questions - beware it's a hefty tome :






Oxford Biomedica plc (OXBDF) Q2 2024 Earnings Call Transcript

Sep. 23, 2024 10:14 AM ETOxford Biomedica plc (OXBDF) Stock

SA Transcripts profile picture

Oxford Biomedica plc (OTCPK:OXBDF) Q2 2024 Earnings Conference Call September 23, 2024 8:00 AM ET

Company Participants

Frank Mathias - Chief Executive Officer
Sebastien Ribault - Chief Business Officer
Lucinda Crabtree - Chief Financial Officer
Stuart Henderson - Vice Chair

Conference Call Participants

Natalia Webster - RBC Capital Markets
John Priestner - JPMorgan
Paul Cuddon - Deutsche Numis
James Orsborne - Stifel
Julie Simmonds - Panmure Liberum

Frank Mathias

Good afternoon, everyone, and good morning to those on the other side of the ocean. Thank you for attending today's Analyst Briefing on our Interim Results for the Six Months ended June 30, 2024.

It's always my pleasure to speak to you today for my fourth set of OXB results. It's also a great pleasure to see so many known faces, familiar faces here in the room. Thank you for joining us.

With me today, and I'm proud to say, our newly appointed Chief Financial Officer, Luci Crabtree, who many of you already know probably from the past and who joined us just three weeks ago, exactly three weeks ago, Luci. We are very excited to have you on board, Luci, and as we embark on a very new or next chapter itself of our journey. And I will let Luci introduce herself when we start her part in the presentation shortly.

I'm also delighted to have our Chief Business Officer, Dr. Sebastien Ribault with us, whom you already know from the past, you will hear from both of them in due course throughout this presentation. Also with us in the room is Stuart Paynter, our former CFO for the Q&A section eventually. And he has recently, as you know, handed over the reins to you, Luci.

The disclaimer. Here's the agenda, in terms of the agenda for our briefing today, we'll begin by providing an overview of the key achievements across the business since the start of the year, before handing over to Sebastien to provide an update on the business development pipeline and the strong momentum we are seeing currently on the commercial side. Luci will then provide an update on our financial performance and then I will hand back to me -- she will hand back to me to wrap up before we start the Q&A session.

So in line with the three pillar plan outlined three years -- last year, we are seeing a strong momentum in all areas of OXB. Indeed, the first-half of 2024 has been a period focused on continuing to deliver on our pure place CDMO Growth Strategy, which was put in place shortly after I joined OXB in March 2023. We have indeed made significant progress in further integrating our global operations to better serve our clients and realize synergies. Under the one OXB strategy, we have now moved to a multi-vector, multi-site model to improve operational efficiency, while offering our clients greater flexibility and accelerated project timelines to help them to bring their life-changing therapies to the market as quickly as possible.

As part of the program of 21 OXB work streams, I'm very pleased to confirm that we have now successfully transferred our lentiviral vector capabilities to our Bedford site near Boston in the U.S. and we are also beginning to transfer our lenti vector platform technology to France. Since the beginning of the year I have been delighted with the commercial momentum we have seen. We have continued to experience very strong demand for our CDMO services and seen a significant increase in the number of commercial opportunities. This is reflected in the quality of the programs we are working on and the number of late-stage programs in our portfolio. We have onboarded new clients across all major viral vector types, including, important to mention here, seven early stage AAV programs in the U.S. and we are very pleased to now be supporting also late stage activities for four clients preparing for commercial launch of their products.

So compared to last year, we have many more later stage programs in our pipeline, and we have started to make selective investment in new talent to support the delivery of these programs in 2025 and beyond. So our pipeline has clearly become more mature, as Sebastien will share in a few minutes. This isn't just good for us. It's also a sign that the whole cell and gene therapy sector is maturing, and we are seeing real progress in bringing these therapies to the market.

There have already been four FDA approvals for cell and gene therapies this year, with three more expected before the end of the year. This commercial momentum is really encouraging and has helped us to develop a more balanced and mature pipeline. In the first-half of the year, we achieved organic growth of 38%, compared to the same period last year, providing clear evidence that the strategy that we have put in place is working. This strong revenue growth has been achieved on a reduced cost base allowing to reiterate the mid-term guidance we set first out last time at the same time last year. Luci will elaborate on this later in her presentation, but I will now hand over to you Sebastien to provide us with a commercial update.

Sebastien Ribault

Thank you, Frank. Good afternoon, good morning everyone.

Let me start with the market situation. We all know that the macroeconomic environment is not very positive these days. But even in a difficult situation, we see that the number of programs in the various clinical phases that you see here on the left is still growing. 5% more than in Q3 2023, with an overall number of clinical molecules that has progressed nicely into the latest phase, meaning Phase 3 and commercial, confirmed by the number of FDA approvals that Frank just mentioned.

Last year, we had seen seven approval, two more than in 2022. This year, again, although the environment is difficult, we expect the same number of approvals. This maturation of the markets and the increasing number of approved program is very important for us, because it's a source of recurrent commercial manufacturing revenue, which we see in our pipeline. And I will elaborate a bit more on that in the next slides.

But starting overall with the pipeline compared to when I joined the company at the end of 2022, where we had a pipeline that was shy of $300 million, where today above $560 million, corresponding to a 94% growth of the pipeline of opportunities across all phases. You see here that the growth was quite similar comparing ‘22 to ‘23 and ‘23 to today, meaning that we expect at the end of the year to be above the number you see here.

More important than just the growth of the pipeline, if you look at the right side of the slide here, you will see that about 57% of our opportunities are covering feasibility studies preclinical Phase 1 and Phase 2 versus 43% in Phase 3 and commercial manufacturing. That's the reason why I was talking about recurrent manufacturing revenue. Because the recurrent manufacturing starts in Phase 2, at the very end of Phase 2, and becomes routine and can be predicted through long-term forecasts when we reach the Phase 3 and the commercial steps.

It's actually what we see in terms of maturity through here on the left side of the slide, risk adjusted pipeline value. So you've seen the pipeline before $565 million. You see here the pipeline adjusted with the probability of success of the ongoing negotiation, including the probability of success through the various clinical phases as well. And when the pipeline grew by 94%, you see that the risk-adjusted pipeline grew even more at 99%, compared to the end of 2022. The pipeline is healthy, well-balanced between the various types of clients, always using the same terminology here with the emerging biotechs, the established biotech and the big pharma.

About a year ago I mentioned that one of my objectives was to make sure that not only we would have the right split between the different types of clients, but also the right split between the existing clients and the new opportunities, which you see here in the middle of the slide. And you see that roughly 50-50 today is the split of the pipeline between existing clients and new opportunities coming from new accounts.

One of the key objective which led to the acquisition of the legacy ABL sites in Lyon and Strasbourg, one of the key objective was also to diversify the pipeline in terms of geographical reach. We had a pipeline that was very heavy on the U.S. side and very poor in Europe. We've moved the pipeline to slightly above 10% in Europe at the end of 2022 to above 30% today. That's the change that we were expecting. It's coming obviously from the ABL acquisition, where a number of opportunities had been identified by the ABL team, but also from the fact that now clients have identified that OXB is a real global player operating from U.S. from U.K. and from continental Europe with the site in Lyon and Strasbourg.

Talking about the split between the phases you see here looking at the line September 2024 that we've increased very significantly the number of projects in the two late phases, Phase 3 and commercial agreement, moving from two projects in September 2022 to six projects in September 2024. That's the reason why we're extremely confident on the revenue generated through the second-half of the year, but also for the revenues of 2025, since all these contracts are linked to projections going through 2025, but also visibility on 2026 and 2027.

Obviously, when you're a biotech today, investing to launch a product, meaning in Phase 3, you want to make sure that there is capacity for your future project and product in the OXB suites and that's why we have a lot of visibility on what's going to happen through next year and the next two years as well.

What's the benefit for our clients? I mean the benefit from our track record and that's the reason why we've been able to acquire more clients on the late stage. It's not only the maturation of the existing pipeline. It's also clients coming to us asking for a tech transfer post-Phase 2 to make sure that we're going to bring them successfully to the commercial stage and taking their project at Phase 3 is maximizing their chances of success.

We have established technology, it's obviously one of the drivers why people come to us and we keep saying that we're a quality and innovation led CDMO. I think that's one of the reasons why we keep winning programs including program at late stage.

I'm going to stop here and hand over to Luci.

Lucinda Crabtree

Thank you, Sebastian. So firstly it's great to see so many familiar faces in the room. I'm delighted to be here and to be presenting this update on OXB results. I've known the OXB business for a long time and with this new clear-cut strategy and focus as a pure play CDMO alongside an incredibly experienced management team. This was an obvious opportunity for me to grasp. I believe this business has great potential and a very exciting growth trajectory, not least because of the ultimate benefit to patients from the therapeutic modalities our viral vector technology platform serves.

Just a few words on me. As you may know, my last role was as CFO of MorphoSys, which was recently acquired by Novartis. Prior to that, I was CFO at Autolus Therapeutics, a NASDAQ listed CAR-T business. And I have a background in both sell side and buy side roles where I will know many of you from. I'm obviously only three weeks in, so it's very early days for me, but I can tell you I have been incredibly impressed with the high energy of the team and my fantastic colleagues on the senior leadership team.

So next slide, please. So as you all know, I joined the business just three weeks ago. Whilst these results relate to the period before I joined, I'm happy to report that there was strong growth in top line, positive results seen from the cost streamlining exercise, which the team executed last year, as well as positive indicators for the future.

Let's start with revenue. We saw an 18% increase in our first-half 2024 revenues to GBP50.8 million compared with GBP43.1 million in the same period last year. Importantly, when you look at organic revenue growth, which excludes the impact of the acquisition of OXB France and the loss of revenues from Homology, our revenues grew 38%. And I think this is an important metric to measure the company's revenue performance by.

Looking towards the future, our KPIs continue to give us confidence. Our revenue backlog figure at the 31 August 2024 stood at approximately a GBP120 million. This metric measures the amount of future revenue yet to be earned and therefore, recognized on our existing orders, sort of like our open order book. As contracted orders are signed, this figure correspondingly increases and as revenues are ultimately recognized, it decreases.

On orders, our contracted value of orders from clients currently stands at approximately a GBP115 million. This has seen an increase since the GBP94 million of orders that we signed -- that we had signed at the end of August 2024. These KPIs and the commercial momentum we are seeing, which you will have heard from Sebastian, are strong indicators of our ability to continue a favorable revenue growth trajectory.

In terms of cash, we had GBP81.4 million in the bank at the 30 June. This compared with a GBP103.7 million at the 31 December 2023. Net cash stood at GBP41.7 million at the end of June, which obviously takes into account the GBP39.7 million of loans which are primarily related to the loan facility we have with Oaktree.

Lastly, with respect to our cost base, we are seeing the benefits of the 2023 reorganization. We reported an operating EBITDA loss of GBP20.3 million, compared with GBP33.7 million in the first-half of last year and an operating loss of GBP32.2 million, compared with GBP50.7 million in the first-half of 2023.

Next, I will discuss our financial guidance. In a nutshell, our guidance remains consistent with the trading update communicated a few weeks ago. We have reiterated both our existing near-term and medium term financial guidance communicated to the market. To recap, we expect full-year 2024 total revenues to be between GBP126 million and GBP134 million with a three-year revenue CAGR of more than 35% for the years 2023 to 2026. This is based on the approximately GBP90 million of revenue we had for the full-year 2023.

On the near-term, we expect a low-double-digit operating EBITDA loss in 2024, which includes the impact of the acquisition of OXB France and investment in talent to support an increased level of late stage client activity in 2025.

On EBITDA, we expect to be profitable on an EBITDA level in 2025. In 2026, we expect to achieve operating EBITDA margins in excess of 20%. Supporting our guidance, we see positive indicators on OXBs growth objectives. As Sebastien has mentioned earlier, our total potential revenue pipeline stands at $565 million, up 29% from $438 million at the start of the year.

This as well as the risk adjusted pipeline, which Sebastian also presented to you, certainly underpins the momentum we continue to expect in new revenue opportunity. And as I previously mentioned, year-to-date, our contracted value of orders stands at around GBP115 million, which also supports this momentum.

Another important indicator we look at is the maturity of our client portfolio, and it has been encouraging to see a high level of more advanced late stage programs. These are potentially higher value programs, and it is promising to see the development of these programs and clients entrusting OXB with their late stage assets, which I think speaks to the credibility of the team in the viral vector CDMO space.

On the cost side, we will continue to exercise prudence in terms of our cost base as we work to build a sustainable and profitable business. All in all, I feel very encouraged by the positioning of OXB in this growth market and incredibly excited to be part of the team.

So with that, thank you. I very much look forward to working with you all. And I'll now pass to Frank.

Frank Mathias

Thank you so much, Luci. Let's come to the end of the presentation. But before I conclude today's presentation, I would like to show you this slide, which is, in my view, at least a powerful reminder of why OXB exists and how our recently launched new corporate values align well with our vision, mission and strategy.

Ingrained in our OXB DNA is our vision to transform life through cell and gene therapy. We want to help to treat seriously ill patients, that's why we feel responsible for our mission. Responsible is our first value. To enable our clients to provide cell and gene therapy to patients in need, we must be responsive. We must be agile and fast in responding to the needs of our clients. That's why responsive is our second value for the company. And because we know that our role is not always as simple as that, we need to be resilient as an organization. We must adapt to change, we must always find solution and persevere. That's why resilient is our third value.

And finally, and this is non-negotiable, we must always show respect. We must build trust with each other and with our clients by being open and honest and respect, at the same time, the environment. So as you can imagine, the three of us, we are, with the rest of the team, very proud to do something life changing together.

So I would like to end the presentation now with a few take home messages summarizing the reason why I have full confidence in our ability to continue to deliver on our pure play CDMO growth strategy. Firstly, we have, and it was mentioned by both, a highly experienced and energetic new management team that is fully committed to achieving our goals. This should also be evident from the results we have presented to you today.

Secondly, the demand for our services is very strong, and we have continued to grow in the market as evidenced by the 55% year-on-year increase in our client base. This demand is significant and this demand and significant commercial momentum has led to a strong growth in our order book, which, as Luci just alluded to, stood at GBP115 million last week in pounds. All of this makes me very confident about our future as a pure play CDMO, and I'm really looking forward to seeing what else we can achieve together for the remainder of the year.

So we will now move to our Q&A session. We will first take the questions from those here in the room. And Sofia, you have a microphone already. I say already a few hands going up. So, and afterwards, we'll take the questions from our lines -- phone lines. So please.

Question-and-Answer Session

Q - Natalia Webster

Thank you. Natalia Webster from RBC. Thanks for taking my questions. I have two please, so my first question's on visibility. So you've got 80% of your 2024 revenues are covered by binding contracts and client forecasts? What is your visibility on the remaining 20%, and what's the equivalent, percentage visibility figure for 2025?

And then my second question is just on revenues. So you've delivered strong organic growth in H1, up 38%. What's your expectations for the contribution from the France and the U.S. sites sort of into the end of the year in 2025?

Frank Mathias

Two questions for you, Sebastian.

Sebastien Ribault

Thank you, Frank. We have full visibility on what's going to happen through the end of the year in terms of remaining order. And actually, I must say that we had to discuss with a number of clients, who have request that we would probably have to postpone the start of some of their project to next year, because the pipeline not only is full, but the capacity is full as well for the end of the year. So, a number of our existing clients know that, the signatures of the contract that will happen in the next week will trigger execution through Q4. And for others, we've already started to discuss execution in 2025. That's always a good news, in our activity to see that, the GMP suites are full and the labs are running full steam.

We're always extremely proactive in these discussions with our clients. We want to show them that, I mean, the capacity has its limits. So we tell people, we express their intent to start before the end of the year very early, that we need decision by June, July, August, September, and so on. We usually know that whatever is signed in Q4, usually corresponds to a start in Q1, and we're already in that situation today. So we have very good visibility. That's also the reason why I was mentioning that we have good visibility on the 2025 revenues as well, since the Q1 and Q2 and even now, Q3 situations, are quite clear.

And my colleague, Thierry Cournez, our chief operating officer, is already working on the people plan for next year to make sure that not only we can deliver on what's been signed, but also we'll be able to deliver on what's going to be signed in Q4.

On the revenues for H2, I did not calculate the growth. I don't know if you did, Luci, what will be the growth of revenue. But since we know what revenue we achieved in H1 and we just reiterated the guidance for the revenue for the full-year, I think we just have to make the math and we'll know what's the growth for H2, but I did not calculate it.

Lucinda Crabtree

Exactly. Yes, I mean, and I don't think it's appropriate for us to calculate the growth. We've given a guidance range and that's been reiterated.

Natalia Webster

I guess just on the sort of inorganic side, the France and U.S. operations, what you're expecting from them? How they're going to ramp over time?

Lucinda Crabtree

We haven't split out. I mean, I think the first thing is that we're looking at OXB as one OXB. So but as you can imagine, there is a lot of potential in France and U.S. to grow revenues and we'd expect that to happen over time. And we did point to seven new AAV programs signed. I think this gives us that confidence in the future growth trajectory across all platforms.

Natalia Webster

Thank you.

Frank Mathias

Sofia? There's an order. Okay, you have to walk more. That's only…

John Priestner

Hi, John Priestner at JPMorgan. Maybe just two for me, please. So you mentioned the high level of GMP Suite reservations in 2025. Maybe you can just kind of help us understand how high that is relative to this time last year going into ’24? And, historically, what percentage of reservations have translated to revenue? So trying to understand can put clients just push a reservation back for 12 months, or have they fully committed to that capacity?

And the second question just on the 2024 guidance. So beyond the, obviously, increase in revenues in the second-half, how should we think about the cost lines developing in the second-half? I think COGS was slightly high in the first-half. So thank you.

Frank Mathias

So, Sebastian, I want to take the one of the reservation capacity.

Sebastien Ribault

Yes. We have planned for 80% suite utilization in 2025. Why 80%? Just because it's good practice to, keep about 20% for maintenance and your shutdown, but also some programs that are going to move from one quarter to the other. So we want to have flexibility. We don't want to be in a situation where some of our clients would be impacted by their clinical studies, timeline variation, and we have no solution to provide them.

Our -- we're talking in terms of capacity based on the suite and resources, [FTSE] (ph) utilization. We have not manned all the suites, for a very simple reason. In our world, a biotech technician needs about six months for proper onboarding and another six months to be fully autonomous, which means one year. And we do not want to manufacture at the level of quality that would be under the level of quality that we had so far. We want to stay at a very high level of quality. So our, capacity utilization is based on the number of people that we have to manned the difference with. And for next year, 80%.

Very similar this year, so not a big change, except that we had less FTSE this year than we plan to have next year. I will have hard time commenting on what happened before 2023 as I joined in November 2022. And before that, as you certainly know, the company, business model was hybrid, internal projects and CDMO works. I'm not sure we had a CDMO capacity utilization number. I'm looking at Stuart, but I'm not sure that number ever existed before.

Stuart Henderson

But the only thing I'll say before you joined, Sebastian, obviously, we have to…

Frank Mathias

Wait, we cannot hear you. We need to take the microphone.

Stuart Henderson

It's just following on from Sebastian's comment. Before Sebastian joined, we were, of course, the utilization was skewed by the by the COVID vaccine, which was, you know, very, very, very high 24-hour a day running utilization for very obvious reasons. So I think that from the time Sebastien has been in, that's probably ground zero in terms of the new way of doing things.

Frank Mathias

But what it says is we can open new suites and by the way that's what Sebastien, we just came from a meeting last week where we try now to look into 2025 with a high level of visibility, which we get. And we know that we might be obliged to open additional suites, that's why we have started this brings me to the cost of the second part of the year. We have started to recruit additional people, because we anticipate additional trained people. As Sebastien said, it takes up to six months to train the people to the level where they are really able to do a great job in the suite. So we have started now to invest in additional people, very prudently because of our new CFO. The cost.

Lucinda Crabtree

So, yes, your question was on cost base. I mean, as you pointed out, we do expect to see progress on our revenues. That's what sits behind our longer term guidance. And what sits behind that EBITDA 2025 guidance is obviously, we expect to grow revenues more than we expect to grow our cost base as you'd imagine. So you asked about COGS, I think H1 2024, you saw an impact from the acquisition of France, which had an impact on our COGS. So I, and of course, the decline in U.S. revenue. So I think those factors are what sits behind the lower margin, in H1, and that's certainly not an indicator of the future.

John Priestner

Perfect. Very clear.

Frank Mathias

Thank you.

Paul Cuddon

Paul Cuddon from Deutsche Numis. Just working through the risk adjustment on the pipeline, there seems to be a big increase in your probability of converting the pipeline in 2024 versus kind of where it was in 2023. So just want to understand some of the drivers there? And just more broadly in the cell therapy market, I suppose I'm noticing a lot more in terms of new targets, combination targets, increased complexity of cell engineering. So kind of how does that sort of fit into your capabilities and your kind of existing cost framework as well?

Frank Mathias

So that's not the conversion rate that change in the pipeline. It's the size of the large scale opportunity that are at the stage of negotiation where the probability of OXB acquiring the target is very high. But the conversion rate is pretty much the same than in 2023. We just have more opportunities, bigger opportunities, and as shown on one of the slides, about 50% of the opportunity is coming from new clients, but also since we have discussions with existing clients, who give us additional programs, we have more visibility and faster on these new opportunities.

I can mention, for example, one of our existing client was a late stage program with us who requested development on an early stage program and already asked us if we could take a second program at late stage. So when you have discussions with existing accounts, the master services agreement is in place. So it simplifies very much the negotiation obviously. They know our terms and conditions. So the probability of acquiring that program is obviously much higher than the discussion that we just start with an account that, that we've known for a couple of weeks only. So that's really the maturity of the pipeline more than the conversion rate that has changed.

On the complexity of cell therapy, it's not something that we see, because in our segments, the way our clients are using the AAVs or the lentis or the adenos is the same than last year and the year before and so on. So there are a number of discussions on IPSCs, for example, but that doesn't change the need to have lenti viruses for CAR-T's. And there are still a lot of CAR-T programs. Actually, if you look at cell therapy, CAR-T is still driving the growth, still. So that's the reason why it doesn't add any complexity for us. We're obviously looking on a real-time basis at the evolution of the markets. There are lots of discussions on new cell types, including non-modified cells. But as of now, that's not impacting our activity, and I don't expect an impact even for next year.

Paul Cuddon

Thank you.

Unidentified Analyst

Hi, [Indiscernible] from Peel Hunt. Just a couple on the France site. You say that you're still integrating lenti vector into France. When are you predicting that OXB France will be fully integrated? And are there any associated costs that you're still expecting from this integration? Thanks.

Frank Mathias

Sebastien on…

Sebastien Ribault

I can take the integration timeline. So we're halfway through the integration process now. It's hard to tell you when the integration will be complete. I mean, if we're talking about the full integration program, it includes, for example, the alignment of the quality management systems and a number of systems, including the ERP, for example, and we know that these alignment take years.

If we're talking about the integration by segments, the strategy and commercial activities are fully integrated. If we're looking at execution today, Frank mentioned briefly that we've started the tech transfer of the lenti vector platform. I know from a discussion with our CEO from last week that we'll have all the activities at small scale and pilot scale fully transferred by the end of the year, meaning that we're on track to have GMP activities in France next year, aligned with what we're doing today in Oxford and soon in Bedford.

I think that the delivery activities will be fully integrated sometimes next year, hard to say now when it's going to be, but before the end of the year for sure. So what we expect to see still running in 2026 will be systems integration only.

Frank Mathias

And on the costs?

Lucinda Crabtree

Well, yes, look, I mean, I think, first of all, early days for me, but, you know, as Sebastian has alluded to, in terms of integration activities, you can assume, you know, at this juncture I don't envisage there being any sort of large associated costs related to the remaining integration activities.

James Orsborne

Hi, James Orsborne from Stifel. Just on the investment going into 2025, I just wondered if you could give a bit of color around headcount, where it is today? Where you expect it to be? And I guess, sort of looking at the slide here in terms of geographical split, where you think you might be under-invested and where you think the opportunities are and perhaps a little color on the personnel you're looking at as well to hire?

Lucinda Crabtree

Yes, look it's a very short answer. I mean obviously, you know, we're coming to that point in time where we start our budgetary activities anyway and you know, I think we will look carefully and add sensibly and carefully to our head count as is required, with the backdrop of retaining that kind of prudent outlook on the cost base. So I'm not going to be drawn into specifics in terms of numbers, but we will be good stewards.

James Orsborne

Okay, thank you. And then just on the inAAVate platform obviously you've built a pretty nice reputation in lenti with the full target CAR-T therapies you got in late stage? How's the AAV market looking with that platform now established? I guess how competitive is that versus lenti that you're seeing as, I guess, a new brand or new person in the space?

Sebastien Ribault

We still have a much stronger reputation on the lenti side, I mean, which makes sense. OXB founded in 1995. When you have almost 30-years of existence in the lenti space, it's hard to compete with only 10-years on the AAV side. But the platform is very competitive. I know from the client feedback directly that they're happy with the performance. That is the reason why we signed, Luci mentioned, it's seven new AAV programs during the first-half of the year. We've seen the volume of orders increasing since the beginning of H2. So very positive on the AAV platform. One of the questions for 2025, and I'm going to put my head of strategy hat for a minute, is how do we combine the existing AAV platform that we had in France that came through the acquisition and the existing platform that we're running routinely in the U.S.

I think it can add even more value to our clients. But so far we've decided that we would continue delivering based on the inAAVate platform, but we're obviously always looking at modification that can bring additional value to our clients.

James Orsborne

That's great. Thank you.

Frank Mathias

Thank you.

Julie Simmonds

Thanks. Julie Simmonds, Panmure Liberum. Just a question on how long it's taking to sign on new clients if -- when they're interested and then given the capacity that you have, what sort of the runway looking like now for a new client coming on board?

Frank Mathias

Yes. That's one of my favorite question, one of the most difficult. It depends what you want. If you want to go through a feasibility study and understand better what's going to be the productivity, the yield, and what if you want to get the first data to have a more precise business model for the future, understand the cost per dozen, it's going to be very quick. So if you were signing today, we would probably start the project in two to four weeks from now.

If you come today and say, I would like to have a full program just before Phase 3, process characterization, validation, it's going to take some time. Because we've seen a very, very high demand in this field. We're talking about programs that are 12 to 18 months of activities. That's actually the biggest program in terms of FTSE mobilized on these programs. I mean, you're preparing for Phase 3 and commercials, so there's obviously a lot of activities.

And if you were asking to start a new process characterization program today, your onboarding would probably be in Q1 next year. I usually say there are five types of capacity on which we're working. Clinical manufacturing; commercial manufacturing; process development; analytical development; and the fifth one, which as I said, is the biggest in terms of volume of activity, process characterization, and validation. So it really depends what you want.

Julie Simmonds

Thank you. And thinking about that in the context of sort of gross margins and how your capacity goes, clearly the margin was quite low in the first-half in comparison to some of the better years. Where do you expect it to get to once you've got that balanced? And how does the second-half of this year look in comparison to that?

Lucinda Crabtree

Do you want me to take that?

Frank Mathias

Yes.

Lucinda Crabtree

Look, you know, again I'm going to sort of say too early for me to give any kind of granularity, but we have our guidance, right? And we've guided to sort of EBITDA levels. Where do we ultimately want to get to as a competitive CDMO business is industry standard margins, right? But I think it's premature for us to give specific guidance as to as and when we're going to hit that. But that is not the ultimate objective.

Julie Simmonds

Lovely, thanks.

Frank Mathias

So is there another question there?

James Orsborne

Hi, a question regarding from Stifel. Just on, you know, just a bit of a context around what's making you win all this new business. You know, you've reset a new commercial team in the last sort of 18 months or so, I'm assuming these are still pretty competitive contracts that you're going after? So what's resonating here? Is it just a factor of more salespeople out there actually able to win this business? Or is there something distinct?

And then related to that, is there any impact? How much does pricing ultimately come into play here in some of these contract wins?

Frank Mathias

We've not touched on the prices. The prices today compared to the prices a year ago or even when I joined the company are very much the same. The main reason why we have more opportunities in the pipeline today is number one, we're more visible. You've probably seen last week the launch of our new brand OXB that we see on the slides here. I was in a trade show in Asia 10-days ago 100% of the people I met knew Oxford Biomedica. 100% of the people I met didn’t know that we were acting exclusively as a CDMO. It's Asia, it's particular, it's a new market for OXB.

I commented with the same audience about 18-months ago that most of the people we were meeting knew us as a lenti company, not lenti and AAV, although we had both. That they knew us as a hybrid company that was developing its own products and a CDMO. If I look at the change, I must say that when we were at about 10% of the market that knew us as a CDMO, we're somewhere between 40% and 60% today based on the latest survey that we ran. Still not a 100%, but more people know us, more people come to us. So we've increased the size of the BD team, we've professionalized the commercial teams as well. We have a real continuum of activities now from strategies, from marketing, commercial operations and biddies, which wasn't the case two years ago.

The team is stable. I'm very proud to say that in my space, in the CBO perimeter, the turnover is 0%. With a stable team, you have stable relationships, and our clients see that. You're not just one number in the middle of the other. We know their need. We try to anticipate as much as we can what they need for the future. I mentioned in my slides, we have the track record. People know that we can push successfully a program into the commercial space.

I know many CDMOs, actually the vast majority who put on their slide were commercial ready. We're not commercial ready. We're operating at commercial scale. That's very different and there are not that many CDMO doing that. So that's the reason why we win more.

James Orsborne

Thank you. And then just a clarification, I guess, on the ‘26 guidance, the 20% margin, is that for the full-year or is that an exit rate at the end of the year?

Lucinda Crabtree

We haven't been that specific, but I can -- I think you can assume that we're looking to achieve that at some point through 2026?

James Orsborne

Thank you.

Frank Mathias

Any other question here in the room? Seems not to be the case, so we open. No questions on the phone. Everyone is here. Yes, there's another question there.

John Priestner

Hi, John Priestner from JPMorgan. Just a quick follow-up question. So maybe thinking about the revenue backlog and the BD pipeline. So are there any projects in there, in the pipeline particular, that have been in there for 12 months or longer? What's the kind of average stay time in the pipeline before it's converted to the backlog? And maybe a similar question from the backlog, are there any revenues in there where customers haven't been able to get their capacity reservation in the last 12 months? Thank you.

Sebastien Ribault

We’re going to start with the end. No, we don't have any client in the backlog that's been waiting. I mean, all of that's been phased one by one when we started the activities. So we don't have a project in the backlog that would start in H2 next year, for example. We're talking about either ongoing activities or activities where the kickoff is imminent.

I flew in this morning and I was sitting on the flight with one of our program managers, was coming here for a face-to-face meeting and the kickoff of a project that we signed four weeks ago now. So everything in the backlog is either in the work or is going to start very soon. It's hard to say what's the standard timeline between the start of the negotiation and the end. It really depends what kind of project we're negotiating. All of them, I believe, are between three and nine months, depending on the complexity of the program.

As you can imagine, we have lots of discussions when all these programs are complex. So we want to make sure that the package is adapted to the need, that the timelines are also in line with the expectations in terms of clinical studies. It's rarely below three months. It's rarely above nine months as well. Six months is a good number for the standard negotiation.

This being said, very specific to your question, do we have programs that have been sitting here for more than a year? The answer is yes. And the reason why we have that and I have in mind specifically one that we discussed with Frank last week, because it's a very complex project that requires alignment between these company and multiple partners with which they operate. So we're waiting for the alignment to make sure that the pipeline management reflect that situation. It's not a program that you would find in the risk adjusted pipeline with a high probability of success, because we're still waiting for the alignment. So that's a very low value in our pipeline.

Frank Mathias

Perhaps you can say a few words also to make it clear for the backlog what it means for commercial products, because then it's a binding that's important I believe.

Sebastien Ribault

The backlog for commercial products correspond to the binding forecast. The shortest forecast we have in the backlog is 12 months visibility, meaning that we already know what they will need in September 2025 and that's binding. So is that waiting for a start? No, it's not. I mean, every month we're delivering additional batches for this company. And although the binding forecast is 12 months, the forecast, the entire forecast is two years. So we know what they will need through 2026 as well.

Frank Mathias

But the two years figures are not in the backlog?

Sebastien Ribault

They are not in the backlog. They are in our forecast, but since it's not binding, they are not in the backlog.

Frank Mathias

Any other question? If this is not the case, let me take the opportunity before I close the meeting to express my thanks to you Stuart, Stuart Paynter for your contribution as CFO of OXB over the last seven years. Yes, so you have given me invaluable support when I started, so thank you again for that. You have been instrumental in bringing OXB also to where it is today, bringing us through the pandemic. And we have to thank you a lot. So thank you so much from the bottom of my heart.

And thank you to all the rest in the room for your participation and attention today. I know that you will be on the road. Luci and Sophia will be on the road over the next weeks. I will join you, by the way, for some yes, but sorry for that. I will be with you. So thank you for coming today and have a nice afternoon. Bye-bye.

Sebastien Ribault

Thank you.

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