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OPTI Optibiotix Health Plc

15.25
-0.75 (-4.69%)
Last Updated: 09:00:24
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Optibiotix Health Plc LSE:OPTI London Ordinary Share GB00BP0RTP38 ORD 2P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -0.75 -4.69% 15.25 15.00 15.50 16.25 15.25 16.25 151,961 09:00:24
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
Noncomml Resh Organizations 457k 2.59M 0.0284 5.37 13.91M
Optibiotix Health Plc is listed in the Noncomml Resh Organizations sector of the London Stock Exchange with ticker OPTI. The last closing price for Optibiotix Health was 16p. Over the last year, Optibiotix Health shares have traded in a share price range of 7.35p to 43.50p.

Optibiotix Health currently has 91,190,661 shares in issue. The market capitalisation of Optibiotix Health is £13.91 million. Optibiotix Health has a price to earnings ratio (PE ratio) of 5.37.

Optibiotix Health Share Discussion Threads

Showing 30101 to 30125 of 147875 messages
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DateSubjectAuthorDiscuss
21/10/2017
14:05
chrisg11 the point is that as in your post below you say "the incorrect assumption" and also " previous levels which is not true."

How can you know it is an incorrect assumption and is not true,have you got the evidence to back that up?This is not a get at you post,but you expect other posters to take your posts as being true but give no evidence to back up why others are incorrect but your posts are correct.


chrisg1120 Oct '17 - 18:02 - 28177 of 28204 0 0
Ferdinand..that is a very reasonable comment but makes the incorrect assumption that the cholesterol would quickly go up to previous levels which is not true..It would go up and is indeed going up even on LP LDL.

edit
As i said in a previous post my lvls went back up to near enough pre statin lvl within 3 months,also someone else posted a piece from NHS site "In most cases, treatment with statins continues for life, as stopping the medication causes your cholesterol to return to a high level within a few weeks".

scotty1
21/10/2017
14:00
be interesting to see the results of LP-LDL coupled with reduced dose of statins, with the goal of previously compare able performance but reduced side effects.
belgrano2
21/10/2017
13:10
chrisg11 - Perhaps you would like to quit now, while you think you're ahead!
asterix96
21/10/2017
12:57
Chrisg11 - What was your expectation? Did you expect that LP-LDL would reduce cholesterol on the same level as Statins? You make comments about lack of 'scientific accuracy' and 'convincing results' - I don't think anyone here has begun 'party celebrations' as you put it. Adnan was taking Statins which were reducing his cholesterol, he stopped taking them and begun taking LP-LDL. My expectation would have been that his cholesterol would be reduced, but not to the level of Statins, which is what his results show. It's not rocket science and I don't think anyone here is making out that we've some miracle cure. I do notice in all of your posts that you in some shape or form try insinuate that the product is unproven or not showing enough evidence of working. It's been tested, it's been taken to market. It works.
loungeact
21/10/2017
12:33
Scotty..I don't dispute your results for one minute,only the interpretation of Adnan's results.

The easiest thing is that if someone suggests that all cholesterols will return to their original highs within 3 months of stopping statin then maybe they will link the evidential study to back up the statement.

The next few months will show us more if Adnan's kindly posts his results and I sincerely hope his cholesterol stays down although as an aside he needs to do something about his level of 6 which is far too high and of course further medication would again confuse the results.

Anyway friendly discussion is the way to go and I hope I have not upset anyone.

I am invested here and I guess the share price will fly when the evidence becomes clearer.

Elrico..

No I'm not trying to compare statins with LPLDL simply trying to interpret very limited result information

chrisg11
21/10/2017
12:20
Hi Sienna

I don't think it contradicts my statement at all as Adnan's cholesterol has moved to a high level even on LPLDL.

The NHS website is correct and the cholesterol will return to a high level in an unspecified time of 'weeks.

It is not saying all cholesterols will return to their original high within 12 weeks which they won't.

My best educated guess looking at Adnan's results is that his cholesterol will have risen again in 3 months hopefully not up to 7.5

We will need about a year of the good doctor's results before we can make a reasonable judgement re what's going on here.

As I keep repeating I am a believer in the microbiome theories but scientific accuracy must be maintained.

chrisg11
21/10/2017
12:13
Wow Parob, there's a lot of info in there.
For instance I didn't realise that the microbiota reside in the Colon as well as the stomach.
So maybe that could open pathways to helping with Crohn's disease and Irritable Bowel Syndrome etc.
Blimey, where is this fantastic journey leading us?
So exciting.
John

2350220
21/10/2017
12:09
Agree with your post rodders and I'm sorry some seem to have taken some sort of offence that I question the interpretation of the results.

It's not in my financial interest to question positive promotion of results but if science is not authentic then it is nothing.

I am sure we will see more convincing results than we have had so far and then I will join the party celebrations!

chrisg11
21/10/2017
11:43
Chris .. I sort of mentioned caution on adnans resuts conclusion in my post 28145 of 28198.

I guess the main thing is to wait 6-9 months before we can confidently talk about effects.

One thing to note is I'm sure someone mentioned about and improved prebiotic and probiotic combination strain in the pipeline which improves upon LPLDL reducing cholesterol x 3.

That would answer all the doubters .. right ?

onedayrodders
21/10/2017
10:49
A Macro Look at the Microbiome

20-10-17

parob
21/10/2017
08:47
This German Healthcare price comparison website now lists 27 sites selling the Lactobact LDL-Control product (up from 11 in July and 24 in August):
parob
21/10/2017
08:45
...Click on the little icon to the right of a user's name. Then click on "Send Message".
someuwin
21/10/2017
08:09
Hi Elric not sure how to PM. What do I use in the box "to" just the user handle??I am away on holiday for a couple of weeks so will be in touch on returnThanksAdnan
adnanwolf
20/10/2017
23:53
Chrisg11,Your comment from post 28177 really got me thinking. I've just copied and pasted the below info from the NHS website which seems to contradict your statement but i'm happy to keep an open mind if you could point me to where your info is from."Taking statins:Statins come as tablets that are taken once a day. The tablets should normally be taken at the same time each day – most people take them just before going to bed.In most cases, treatment with statins continues for life, as stopping the medication causes your cholesterol to return to a high level within a few weeks.If you ever forget to take your dose, don't take an extra one to make up for it. Just take your next dose as usual the following day.If you accidentally take too many statin tablets (more than your usual daily dose), contact your doctor or pharmacist for advice, or call NHS 111."CheersSienna
siennadelekat21
20/10/2017
21:55
Amazing how such great results can bring on slightly negative comments instead of celebrating the success. No wonder the brexit negotiations are swamped with doom mongers! I’m wishing Opti nothing but the best with their products!
moormoney
20/10/2017
21:52
I don't want to get involved with medical matters I know nothing about, especially as I don't suffer from high LDL, thus never taken medication for it. Chris makes a valid observation in the Adnan's cholesterol level increased by .5. However, what Chris seems to be missing the fact LP-LDL is in OTC supplement form produced by HLHBiopharma and I dare say there will be variables to OTC supplement manufactured to pharmaceutical specs in other territories and I would imagine have differing results, but within a range. Chris appears to comparing statin, as pharm medicine with LP-LDL an OTC supplement - You simply cannot compare them. OPTI have never made the claim LP-LDL can replace statins, but they have suggested it can be used in conjunction with. I take this to mean statin dose (in some cases) could be reduced if LP-LDL was being used. What is clear, the higher the LDL the better the results with LP-LDL.

Another point SOH made: "We also know from other studies that cholesterol can vary 5-10% throughout a day within an individual depending on the food they eat and the timing of testing and so a result based on a single subject can be subject to other factors which can mask an effect." We don't know what time Adnan's was tested, but we know he ate some lovely sweet treats the evening before, which I would imagine impacted on the negative side, so it is entirely possible the result could have been better than had he not buckled to his sweet tooth. ;)

elrico
20/10/2017
21:23
Adnan - SOH is asking me for your contact details. Please PM me so I can pass on your details to SOH. I can assure you I will NOT share with anyone else.

"As with Nick if you have his contact details it would be good to be able to get my PR company to speak with him as we are putting together an article covering the problem with pharma drugs in this area and our study data and it would be good to finish off with a few case studies of Nick and Dr Adnan."

elrico
20/10/2017
19:41
chrisg you posted

"Ferdinand..that is a very reasonable comment but makes the incorrect assumption that the cholesterol would quickly go up to previous levels which is not true..It would go up and is indeed going up even on LP LDL."

the above post of mine was to say that in my case it DID go back more or less to my previous lvs infact it could have been quicker than 3 months it's just that it was not tested until 3 months after stopping taking them.

How can you say ferdinands comment is incorrect and how can you say it is not true ?which in my case it was,what experience or knowledge have you in that field to make such comments

scotty1
20/10/2017
19:25
Scotty..next time I post scotty I will post outlandish interpretations of an increasing cholesterol and for you and risky when I report the conclusions of a scientific study I will deliberately miss out the word potential from the study conclusions and then everyone will no doubt be happy.
chrisg11
20/10/2017
19:14
chrisg i have been on statins for many a year after being able to control my cholesterol with diet only for years before taking statins since being on statins i have suffered bad muscle cramps.4 months ago i told my GP i wanted off statins again and wanted another go at controlling it by diet only.So thats what i did for 3 months a ridged diet i managed to loose 1.5 stone and felt sure my overall lvls would be down after a fasting test.Top and bottom is the lvls had gone back almost to pre statin days which i couldn,t understand as i really had no saturates and almost stuck to a fruit,fish,veggie diet,but as my GP said when you get into your 60s your body produces cholesterol no matter what you eat.The point i am making is that within 3 months of coming of statins my lvls had gone back up to within 0.3 of my pre statin days.I believe the idea is to use LPLDL in conjunction with satins ie if you are on 40mg drop it to 10mg (thus minimizing the side affects)and use LPLDL along side it.
Other than that m8 i see you have only posted 11 time all on OPTI and all with a negative tone.

scotty1
20/10/2017
19:07
'To keep it simple and understandable,this means that if LPLDL does indeed turn out to lower cholesterol this does not mean with certainty that it will lower cardiovascular risk significantly'See below.... we know LPLDL reduces cholesterol and Optis study also showed a decrease in blood pressure across the board which seems to have replicated with nick and Adnans recent findings.....The European Society of Cardiology Studies has reported the ability to reduce both cholesterol and blood pressure 'has a multiplicative effect in reducing cardiovascular risk' providing a significant advantage over single action products.
riskybusiness1
20/10/2017
18:59
The official results are exceptionally promising. Opti now have a string of evidence supporting LPLDL from lab studies, replica gut models and now human studies that have all replicated previous findings. Optis study of 50 reinforces previous evidence proving efficacy whilst also showing safety which is clearly key. 50 subjects is usually pretty similar to a pharma phase 2.There will need to be further trials e.g 100 - 200 people. A human study that includes the subjects taking a combination of LPLDL and LPGOS will be extremely interesting and if replicated earlier findings will take Opti to a whole new level of opportunity. The LPGOS fibre increases LPLDLs own efficacy x3 times in gut models whilst also having its own cholesterol reducing property. Optis LPLDL study was also on people with normal to mildly elevated cholesterol levels. The study by university of reading shows that the greater the starting cholesterol levels the greater the reduction. We know SOH has stated the next trials will be with subjects with higher starting cholesterol levels.Opti is very much at the front in terms of science in the birth of a revolutionary new market. I don't think any other company in this space has modulated the microbiome with such precision as has Opti using its patented reverse enzyme technology to extract a specific fibre from a specific organism (LPGOS recent deal with TATA). Very exciting space to be invested in.
riskybusiness1
20/10/2017
18:43
To make things clear..I am not trying to fall out with anyone on here but feel it is healthy to give another view and perspective on things.

A more complex spanner in the works which I now offer with a wry smile and wearing a tin hat is that the cardiovascular protection given by taking a statin is only poorly correlated to the cholesterol level.

To keep it simple and understandable,this means that if LPLDL does indeed turn out to lower cholesterol this does not mean with certainty that it will lower cardiovascular risk significantly but I would agree a bit of mischief with this particular comment.

chrisg11
20/10/2017
18:34
Johnhenry..

I am not sure of your expertise to say I am correct but you cannot make the conclusions you are doing from the results given.

You make an incorrect statement that the cholesterol would return to its 7.5 level within 3 months..It may do,it may not as it may take longer than 3 months.

chrisg11
20/10/2017
18:30
My cholesterol levels are in range 4.5, but my triglycerides are at 4 (max I believe is 2).Not started Statins. I recall this product also having good results on triglyceride levels.May give it a go.
vanduke
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