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ORPH Open Orphan Plc

10.00
0.00 (0.00%)
03 Jul 2024 - Closed
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Open Orphan Plc LSE:ORPH London Ordinary Share GB00B9275X97 ORD 0.1P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  0.00 0.00% 10.00 9.50 10.50 - 0.00 01:00:00
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
0 0 N/A 0

Open Orphan Share Discussion Threads

Showing 12801 to 12825 of 30350 messages
Chat Pages: Latest  518  517  516  515  514  513  512  511  510  509  508  507  Older
DateSubjectAuthorDiscuss
05/2/2021
17:41
Great technical analysis just double the number and that's where the share price will go - you really couldn't make it up !!BWAHAHAHA
12toes
05/2/2021
17:38
tradeTime currency price volume tradeValue type micCode tradeType
2021-02-05T16:29:11.163 GBX 27.71 40000 11084 Off-Book AIMX LRGS
2021-02-05T09:22:59.653 GBX 27 400000 108000 Off-Book AIMX LRGS
2021-02-05T15:46:38.610 GBX 28.156 30000 8446.8 Off-Book AIMX LRGS
2021-02-05T15:46:38.573 GBX 28.156 38268 10774.73808 Off-Book AIMX LRGS
2021-02-05T15:46:31.637 GBX 28.16 38000 10700.8 Off-Book AIMX LRGS
2021-02-05T15:45:09.613 GBX 28.16 30000 8448 Off-Book AIMX LRGS
2021-02-05T15:42:57.880 GBX 28.39 36984 10499.7576 Off-Book AIMX LRGS
2021-02-05T15:42:13.543 GBX 28.4 35211 9999.924 Off-Book AIMX LRGS
2021-02-05T16:35:35.403 GBX 28.5 75000 21375 Off-Book AIMX
2021-02-05T16:35:25.990 GBX 27.9 50000 13950 UT AIMX
2021-02-05T16:27:56.707 GBX 28.125 3000 843.75 Off-Book AIMX
2021-02-05T16:27:11.947 GBX 27.7 16399 4542.523 Off-Book AIMX

sh0wmethemoney
05/2/2021
17:30
Quite a few decent delayed prints coming through now.
bearnecessities
05/2/2021
17:13
27.9p in the UT, the 28.5p was just delayed reporting wasn't it?

But a great week, all the same.

1gw
05/2/2021
16:39
Nice 75k at 28.5p in Auction to close out a good week
sh0wmethemoney
05/2/2021
16:05
Well this is certainly nice to see, especially after countless positive RNS's failing to make an impact. Long may it continue as we've been plenty patient here.Amazing what a bit of volume does here, with a nice dose of sentiment.Hoping now that this a proper attack on the 30's, and when we get there we hold there at the very least.
bearnecessities
05/2/2021
16:04
Has to be more than coincidence the 6,12,24 thing but Invesco weren't selling back then. Bring on 48 anyway.
discojames
05/2/2021
15:35
Thought there might be buyers later today on the small price drop.

There's no instituional seller here these days, pretty sure of that. Clear road ahead to 48p i reckon, judging by the seller's behaviour ... sell at 6p, pause until 12p then dump a few more, pause until 24p then dump some more ... and now waiting for 48p to dump the rest, which can't be many, if invesco.

No idea if there's anything in that, but it's sure a lot better than many of the theories some of the new posters here dream up.

I think with the w/e press any buyers will have to pay more than today on Monday.

Quite a good week ..... And the sun's out!

pierre oreilly
05/2/2021
15:31
clearly broken out now.
c0lin1
05/2/2021
15:31
That's exactly what he said they would in the presentation !
bobsworth
05/2/2021
15:24
Happy Friday all. This adds some bounce to the weekend :)
greenelf
05/2/2021
14:39
Hi Lhoskins,

Good point I should have mentioned that CF stated on the presentation the new facility is booked until the middle of the year already.

thomas11
05/2/2021
14:36
Couldn't he simply move the non covid trials from hvivos negative pressure clinic to the new facility across the road ?
lhoskins
05/2/2021
14:14
Hi all,

As prev. mentioned, I took part in a zoom focus group meeting last night, hosted by Imperial, as part of feedback for Ethics Committee (we were told) - maybe , per today's news, a decision has already been reached.....

Snippets :

- Catchpole was in attendance but didn't say anything in the Group session and wasn't part of my 'breakout' group subsequently;

- emphasized that goal was to calibrate MINIMUM dosage of live virus needed to trigger a response;

- some concern that public attitudes may now be less 'pro' because of vaccine rollout, this was reflected in some participants' views, others had changed the other way through family/friend experience (incl fatal) since last group mtg in Oct

- some question of whether able to get appropriate BAME representation (interest/willingness on the one hand vs considerations of possible 'extra risk' predisposition on the other);

- sidenote : there was only 1 x obviously BAME participant in our 30-person group;

- sidenote 2 : most of the Group session was led by an ethnic Chinese hxxps://www.imperial.ac.uk/people/c.chiu

- the 'window' for covid -19 related conventional vaccine testing 'in the wild' is reducing, because of rising 'herd immunity' in the UK (combination of natural exposure and vaccination), placing a premium on small number/quick result under controlled conditions offered by HC;

- suggestion that - if variants cropped up that rendered existing vaccines ineffective - a successful HC outcome using an experimental new vaccine would make it easier to argue [Ed,: and give political cover ]for 'fast-track' approval ie quicker off the mark if there's a resurgence /new pandemic in future;

-acknowledgement that HMG had accelerated approval of AZ and the change in dosing gap on the basis of 'opportunity cost' considerations - partial cover for many , rather than fuller protection for fewer.

All IMO and as I understood things.

HTH

extrader
05/2/2021
14:09
Interesting CF can’t offer Trials in Covid as he has no capacity available, the Royal Free is for the government trials and the QMB clinic is booked all year. The Whitechapel is only for non Covid.

As we now know from the presentation the non Covid trials do not need the negative pressure facility, this is massive news to me and I hadn’t appreciated the significance until now. Many Many posters here assumed we needed a negative air pressure facility for all trials and this was the limiting factor. Hence everyone looking for negative air pressure clinics globally.


This means he can get the additional hotel beds for non Covid and transfer the non Covid trials from QMB to another facility and free up QMB for Covid studies. The studies should be ready from May so an additional facility is required before then.

This will really accelerate the income from Covid trials this year, exciting times ahead.

GLA

thomas11
05/2/2021
13:40
Yeh I think that and CF actions ramping up operations and capacity tells us what we need to know, the train is getting ready to leave the station, all aboard!!!
sh0wmethemoney
05/2/2021
13:10
Cheers Trader 3, yes all positive and looking good for the future.
sh0wmethemoney
05/2/2021
12:42
SMTM - Great confirmatory news & find.

Clearly this section has now been passed by the Ethics Committee & bodes extremely well for the full study approval.

Not sure if the market will pick up on this significant milestone, as it may not be RNS'd due to being run by Imperial College. However, its a great buying opportunity for informed PI's, who know & understand the ORPH story.

GLA LTH's

trader_3
05/2/2021
12:38
Share price right now is a total irrelevance I am tending to agree with m5. The amount of money that is going to come our way in the next 6 months is I believe massive.
The DIM database company I believe CF when he says it could be worth the current market cap of ORPH, if you look at the valuations on medical database companies not making a profit and you look at the database we have that is going to be generating huge amounts of cash from day 1 via rental to FAANG type companies you will need to sit down. This sector was highlighted by CF in Sept 19 as a hot area of investment even then.
The disposals of the other non core should provide another bag simply because one asset, Flu V, has as simple comparator of a similar stage vaccine going for $400 million last year, we only own 49% remember, so that alone is a bag almost.
Now a 2+2 from me. CF highlighted they were looking very closely at another hotel to convert to non CV19 challenge studies add that to the meeting yesterday with 7 Chinese companies and their regulator and I get the need for expansion with another closed hotel of approx. 100 beds capacity that CF was talking about. Therefore we can start thinking about at least a doubling of income compared to our current 61 bed capacity if my arithmetic is right.
I really hope more people sell this I have been selling down a few other company shares this week as I focus more on short term good newsflow companies so have a nice amount of cash looking for a home.

pogue
05/2/2021
12:26
Doing really quite nicely today. Volume is quite high and the price is stable.
lako42
05/2/2021
12:13
arab3, no I'm in for the long haul.
toyin
05/2/2021
11:39
I have absolutely no issue with traders. Its all about making money and there is more than one way to do that.We all have different circumstances and bills to pay etc. It's not a one size fits all business.

However, if you can hold, I am not sure why you would sell right now. As I have said before, I look everyday for a better opportunity, I have no allegiance to this share,I am not emotionally attached, I am not long and strong and all the other BS sayings, its about making your money work and managing risk EOS.

I still can't find anything better out there right now, short, medium or longer term. Please DYOR.

Not any advice, just how I see it. Early finish for me. Sun is shinning, it feels bloody tropical after the last few days, so its walk time. A good week, and a cracking presentation by CF. Forwards and onwards. Have a great weekend all.

m5
05/2/2021
11:33
At least you have given an insight as to the reason for some of your comments.


Buy the dips, obvs.

lako42
05/2/2021
11:07
Do you sell the rises toyin ?
arab3
05/2/2021
10:54
Buy the dips Judi, always buy the dips😉㈇9;🏻👍🏻
toyin
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