Immupharma Share Discussion Threads

[w1ndjammer] 20/2/2018 13:27

its greed that will kill you spread betting in 12 years i have only had 1 margin call
and that was in the crash, but made a killing on the way back up.

If you cannot control your emotions DO NOT spread bet

i only play with 10% of my total money tied up in the markets so 90% i own
real stocks outright.

all newbies will lose money weather on the spreads or buying stock outright,

WJ.

[dontshoutatonce] 20/2/2018 13:20

Quiche, I am talking about a few years ago. That certainly wasn't the case then.

[hamhamham1] 20/2/2018 13:12

I am not giving any advice. SB is not for me. Was jist saying you never know how far a share price is going to fall, so if doing a SB then be prepared to lose your deposit or to keep totting up the deposit to lower the cut off point. (That is if you manage to do it before you caught out)
I like sensible amounts of real shares and sleep.

[gisjob2] 20/2/2018 13:08

Lodgeview,

Obviously your trading strategy is up to you but allowing for the spread, just be aware that 15% can easily be stopped out if there's a wobble, like we've just seen.

It's a judgement between what you can afford to lose if your stop kicks in and weighing that against trying to make sure your stop isn't triggered.

It's tricky which is why people don't rush to spread betting

[davew28] 20/2/2018 13:01

mcdermov
19 Feb '18 - 17:10 - 14577 of 14753
0 1 1
How on earth do you know Zimmer remortgaged his house??

Courtesy of Bermuda #2576, #2577

around 3 minutes 40 seconds

[lodgeview] 20/2/2018 12:58

I know about margin calls and the like and have been severely burnt playing the indices as some of you know. ham, From what you are saying I agree with the breakdown but taking a 15% loss is surely having an exit strategy? Or are you saying buy at 181 and hold regardless?

[ashehzi] 20/2/2018 12:55

from 30min, Alan Green of Brand Comms talking about IMM.

ps. some good points there to listen to...

[costax1654x] 20/2/2018 12:55

If p140 successful with lupuzos as well 10£ ?per share!!!

[stealth wealth] 20/2/2018 12:51

Interested parties will now be looking at not just Lupuzor for lupus, but the wider P140 platform of which Lupuzor is a part.

[stealth wealth] 20/2/2018 12:48

tt thanks. I like this bit (highlighted):

Lupuzor / P140 Platform, Sylvianne Muller, Jun 2016:
4 min 40 sec:


SM: "We started with lupus but we think we can open the indications(s) in which the peptide will be effective...like asthma"

Interviewer: "...That would obviously lead to a considerable expansion of your target market, going from lupus to many other autoimmune diseases."

SM: "Oh yes, oh yes...we think we can correct the defect in other indications so now we are trying the peptide in other autoimmune and non-autoimmune diseases...[for other indications]...we know the molecule is safe...so we can directly engage Phase 2b or Phase 3 clinical...of course its a plus, because we will shorten the duration of clinical trials and by definition the costs..."

[wigwammer] 20/2/2018 12:48

Thanks TT. The 2016 presentation is highly informative. Key point for me relates to mechanism of action - 25mins-27mins. Lupuzor concentrates in the spleen - bringing it into close contact with high concentrations of the T and B cells implicated in Lupus. This concentration explains not only safety - only a low dose of a small molecule is required - but also the efficacy - targeted interaction of the active drug with the relevant cells. GLA :)

[ashehzi] 20/2/2018 12:41

Spread betting and margin calls. If somehow these margin call investment companies get hold of your phone number and know you've plenty to spend, they keep coming back to you. Why? They know they will get that money sooner or later because of blown up positions.

[gisjob2] 20/2/2018 12:33

I agree with most of what has been said about spread betting, it sounds much easier than it is and can easily be a disaster. Enter it with your eyes wide open.

IMM is the only spread bet I have at the moment and I don't envisage it replacing my normal shareholding methods. It just suited in this one instant at this time.

However my main IMM holding is still a conventional one !

It's a mugs game to think that you can replace conventional share holding with spread betting

[top tips] 20/2/2018 12:31

We have several possible blockbusters here.

[top tips] 20/2/2018 12:30

Enjoy the comments from Sylviane Muller about the other Lupuzor - P140 indications:

Sylviane Muller, Lupuzor Symposium, Jun 2016
How Lupuzor works:

15 min 40 sec:

Evidence Lupuzor P140 works for other conditions:

41 min 30 sec:

Efficacy with other conditions verified by other independent researchers who are experts in these diseases e.g. Crohn's disease, Asthma, etc:

45 min 50 sec:

As P140 proven to be safe via the Lupuzor trials, testing of it for other conditions can start at a Phase 2b or Phase 3, meaning approval for other conditions can be less costly and accelerated timewise:

46 min 16 sec:


Lupuzor / P140 Platform, Sylvianne Muller, Jun 2016

4 min 40 sec:


SM: "We started with lupus but we think we can open the indications(s) in which the peptide will be effective...like asthma"

Interviewer: "...That would obviously lead to a considerable expansion of your target market, going from lupus to many other autoimmune diseases."

SM: "Oh yes, oh yes...we think we can correct the defect in other indications so now we are trying the peptide in other autoimmune and non-autoimmune diseases...[for other indications]...we know the molecule is safe...so we can directly engage Phase 2b or Phase 3 clinical...of course its a plus, because we will shorten the duration of clinical trials and by definition the costs..."

P.S.
Sylviane Muller - Treating lupus by targeting T-cells (SHORT) May 2017

"The peptide has now become medication, Lupuzor - due for market launch in 2018"

[top tips] 20/2/2018 12:28

spreadbetting is designed purely to relieve small investors of their money as quickly as possible. Its just gambling. Even worse is those small investors only go into it because they do not have sufficient funds to take normal long positions via conventional shareholdings. Avoid, avoid, avoid and go long IMM and a balance of other investments via normal routes.

[gisjob2] 20/2/2018 12:28

Quiche,

Dead right ! I can't say I'm a fan of spreadbetting because timing is crucial and it's easy to lose money, but in a situation like this it seems the right thing to do and can also be good to hedge a large shareholding.

[hamhamham1] 20/2/2018 12:27

Lodge. And when you deduct the difference between the buy and sell (the spread) those figures can be a lot, lot easier to hit.

[hamhamham1] 20/2/2018 12:25

Lodge. If you would have opened a spread with a 15% safety net at:

180p - lost deposit at 153p
170p - lost deposit at 144p
160p - lost deposit at 136p
140p - lost deposit at 119p
130p - lost deposit at 110p

At all points you would have lost your money, you may have even re-entered several times and lost again.

It's only good if you think the bottom is near or called.

That's why some have the full shares.

(and yes I did ignore the extra 3% bit for guaranteed stop, was just for illustrative purposes only)

[quiche66] 20/2/2018 12:23

Donthouts - that is not correct with IG. From their website: ""Use guaranteed stops for watertight protection against slippage" and that "Attach a guaranteed stop to your position, and it’ll always be closed out at exactly the price you specified." And it defines slippage as "When a market moves a long way in an instant – or ‘gaps’ – any orders you have placed may be filled at a worse level than the one you requested. This is called slippage."

Couldn't be much clearer really - it is guaranteed but you pay a premium for it. A great option to have in a situation like Immupharma.

[dontshoutatonce] 20/2/2018 12:22

I used IG and lost a lot of money. I couldn't win the argument against them. Just stopped using them. Nothing is guarantees as far as I have found. Trading is no piece of cake, whatever the rules are.

[gisjob2] 20/2/2018 12:19

Lodgeview

They are ! lol

It's not as easy as it sounds, people get greedy and set there stops to tight and get taken out. The spread is bigger, especially if you are choosing a longer term position rather than day trades etc. Nothing is perfect, but it's an alternative. A lot of people take an opposite position to their main shareholdings to hedge there positions.

Note, it's well known that over time not many people make money spreadbetting, you need to be selective and it's all about timing.

[cockerspaniel] 20/2/2018 12:19

I stand corrected - apparently it is a term of business and the counterparty guarantees a 15% stop, thereby assuming the rest of the execution risk (which could be 90p a share, if the shares open around 10p).

That's not something they are going to be happy with, so they will have every incentive to get out of that position and use that stop to do so.

[lodgeview] 20/2/2018 12:13

Then surely it's simply a no brainer to open a SB long with a guaranteed stop. Why doesn't everyone do this!?

[gisjob2] 20/2/2018 12:11

Ham, your calc isn't quite right, you will have to have a margin including 3% for the guaranteed stop loss, but the idea is correct. Best to just play with the website, it explains and adds all the costs for you before the transaction. The additional margin varies depending on the share you select