Synairgen Share Discussion Threads

[wetdream] 31/5/2020 08:00

I’m sure that Synairgen’s primary focus will be on a licensing deal for SNG001.
If correct, I can’t see that their share price will have any influence.

[pdt] 31/5/2020 07:50

Interesting new research;

Efficacy and safety of interferon beta-1a in treatment of severe COVID-19: A randomized clinical trial



Results: As primary outcome, time to the clinical response was not significantly different between the IFN and the control groups (9.7 +/- 5.8 vs. 8.3 +/- 4.9 days respectively, P=0.95). On day 14, 66.7% vs. 43.6% of patients in the IFN group and the control group were discharged, respectively (OR= 2.5; 95% CI: 1.05- 6.37). The 28-day overall mortality was significantly lower in the IFN then the control group (19% vs. 43.6% respectively, p= 0.015). Early administration significantly reduced mortality (OR=13.5; 95% CI: 1.5-118). Conclusion: Although did not change time to reach the clinical response, adding to the standard of care significantly increased discharge rate on day 14 and decreased 28-day mortality.

My Comment - These are severe patients at a later disease stage than SNG trial. IFN was by injection. Trial still showed benefit with earlier discharge and decreased mortality. Encouraging.

[nojjer41] 31/5/2020 07:49

Well I guess we all invest based on what we think at the time. Decisions after the outcome then either look like the works of complete genius or acts of utter folly :-)and I suspect Synairgen is going to be one of those polarising cases. I have invested here further than I originally intended, and like all losses, if that were to happen it would sting a bit, but fortunately it will not break the bank here. However,I believe it is looking relatively positive at the moment. We are likely going to get a clear nudge of direction in this, one way or another, with the COPD results in the next few weeks. The research I have followed suggests to me this product will work in all 3 current trials, and lead to partnership with a larger company. That makes complete sense to me. Nothing is guaranteed with this, of course, there are sizeable risks and it will still have a long way to go even after positive results, but on balance I believe there is an opportunity here. So GLA, let’s hope we are smiling after the first results come in.

[wetdream] 31/5/2020 07:40

I’m aware that placebo can sometimes be a surprisingly strong competitor(!), but it would be a major disappointment if SNG’s current trial couldn’t replicate the earlier Wuhan conclusions:

‘...the findings presented here are the first to suggest therapeutic efficacy in COVID-19 disease of IFN-α2b, an available antiviral intervention. Furthermore, beyond clinical benefit to the individual patient, treatment with IFN-α2b may also benefit public health measures aimed at slowing the tide of this pandemic, in that duration of viral shedding appears shortened.‘

[nobbygnome] 31/5/2020 06:44

Yes it is nowhere near my biggest holding. The relative risk means a proportionate investment is merited here IMHO. Hopefully all investors here know the risk they are taking as I have said all the way through.

[crookie3634] 30/5/2020 23:28

I’m playing I am not in that deep:) it’s my highest holding but got others so have spread my risk. I can afford not to touch it but I am hoping it does well enough to turn out well in the next couple of years. There will be bread on the table without it.

[itshenderz] 30/5/2020 22:55

Agreed, life savings on any stock is a huge gamble. Especially in this climate, hope it pays off for you but be prepared to lose a fair chunk if results aren't successful.

[brokenbuckles] 30/5/2020 22:32

Crookie... watch yourself. Going hard with your life savings in a stock that could drop 80pc if they have a bad trial result is well ballsy. Dont care what anyone ln this board says, no one really knows the outcome. Drug results, oil and gas exploration... everyone's always bullish (especially the ceos) right up until disaster (not saying that will happen here).

[scrabster1] 30/5/2020 22:28

Hi Nobby - seems to be a lot of them on here. Can you do us a favour and give us a list to filter please ? Cheers. Dereky.

[spartan attack] 30/5/2020 22:03

1marc1r

I wish you were man enough to go by your own name too

But for all I know your just a little girl. ..

[1marcr] 30/5/2020 21:53

You really are a prat. Someone needs to give you a slap.Joseph Sheedy Serial Prat

[spartan attack] 30/5/2020 21:41

I bet peachie said something nice.

[peachie 74] 30/5/2020 21:38

I bet the response was genius !

[spartan attack] 30/5/2020 21:33

Her come the OPTI losers again. The only ones complaining

hahaha

[peachie 74] 30/5/2020 21:23

Christ. I’ve filtered , but can see it’s posting frequency. I’m intrigued to picture what this loose canon looks like and is !!!! The mind boggles :))))

[nobbygnome] 30/5/2020 21:18

And the rest of you will be realising his incessant posting is not normal behaviour. Essentially he is deranged and should probably deserve our sympathy if he wasn't such a thoroughly unpleasant character.

[nobbygnome] 30/5/2020 21:15

The rest of you are beginning to see what a destructive character he is. He is only happy if he is ruining threads for everyone else. Please just filter him and don't respond!

[spartan attack] 30/5/2020 21:00

Probably on 99% of those here to be fair

the survivors of the bear pit, shall reap the morphing to bull

[crookie3634] 30/5/2020 20:55

So any buy recs are wasted on me

[crookie3634] 30/5/2020 20:54

I don’t have any spare money have put my life savings into this one! And more.

[spartan attack] 30/5/2020 20:54

Well to be honest, most find that filtering me is the best solution

haha

[crookie3634] 30/5/2020 20:53

If that is the only way then so be it

[spartan attack] 30/5/2020 20:53

It does. Well it should.

But in all fairness, shouldnt filter me

If i ever make a buy call here, its the only one worth pondering

[crookie3634] 30/5/2020 20:52

Have you made 3000 posts in the last 24 days?

[coxypete] 30/5/2020 20:52

Just filter it's the best way