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Share Name Share Symbol Market Type Share ISIN Share Description
Shield Therapeutics Plc LSE:STX London Ordinary Share GB00BYV81293 ORD 1.5P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -1.00 -1.08% 91.50 89.00 94.00 92.50 90.50 91.50 62,913 10:09:39
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Pharmaceuticals & Biotechnology 0.7 -9.1 -8.0 - 107

Shield Therapeutics Share Discussion Threads

Showing 5926 to 5948 of 6350 messages
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DateSubjectAuthorDiscuss
25/5/2020
07:32
>> best Oh dear, you mean you might have to wait a whole one more month.....it is tragic everyone is so short term these days!
nobbygnome
24/5/2020
22:40
FinnCap 22/05/2020 Shield Therapeutics (STX): Corp FY 2019 results Shield reported FY 2019 results that showed sustained momentum from Norgine’s promotional activity of Feraccru in England and Germany, with in-market pack volumes c.70% higher than in 2018. Revenues of £0.7m compared with £11.9m in 2018, which included £11m of milestones. This resulted in an adjusted net loss of £6.3m (vs +£1.1m). Net cash at 30 June was £4.1m, providing a cash runway into Q1 2021, which excludes potential significant up-front payments and milestones for US rights to Accrufer, which are currently being negotiated. Despite minor changes to forecasts, reflecting the later-than-modelled introduction of Feraccru/Accrufer into the broader EU market and US, we reiterate our 350p target price, which reflects the long-term nature of market exclusivity, peak market share (20% assumption) and rolling forward the start year for our DCF calculation, rather than near-term sales. This excludes the potential value of the US milestone, which we have stated in the past could be $50m with $100m+ of commercial milestones.
peachie 74
24/5/2020
21:59
“Our UK manufacturer is currently working on a campaign to manufacture around 12.5 metric tonnes of ferric maltol which should be completed by the end of September 2020. This will provide us with sufficient API to last throughout 2021.” Quote from trading update So what does 12.5 tonnes relate to... 7.4m bottles of 56 caps at 30mg each. A lot. If you guess a 20% royalty on gross revenue and a UK list price of £47.60 in all markets that is £70m from that one order of API. If anyone gets a different number , fire away ..... Not insignificant!
peachie 74
24/5/2020
20:13
>> ewan It is patently clear that we haven't got a US licensing deal yet. It also clear that in the short term the signing of said deal will be the value driver particularly from the current lowly level. Simples!
nobbygnome
24/5/2020
16:54
Fair enough Ewan. Perhaps better you don’t top up then. Good luck.
peachie 74
24/5/2020
15:44
Peachie,I may be showing some lack of knowledge of the pharma processes (in which case I am very happy to be enlightened) but the 'solid results' I was expecting were :US outlicencing. The lack of this is an increasing concern and moving towards a 'red flag' if we don't get something in the revised timescale of H1/2020 (just over a month away). We were in discussions with potential licencees even before FDA approval. Commencement of sales into Europe ex UK and Germany. I thought that Norgine would crack on with that, but it seems they are still some time away from commencing sales. Development of Australia and New Zealand. I have found nothing on this since the announcement. We aren't even mentioned on the norgine.com.au website.Big increase in UK and German sales. 67% increase looks impressive initially but arguably not from a low start and comparing our small, specialised and cash-strapped sales team against the might of Norgine's machine.It would be reassuring if you could counter the above points, because I am increasingly nervous. Thanks!
ewanwhose
24/5/2020
12:48
Haha. Dave you shouldn’t judge a book by its cover ! A finance guy is perhaps what they need atm
peachie 74
24/5/2020
12:44
Yep, fair enough. You've met him and I haven't. Hope it works out for everyone concerned in the not too distant future. Fingers crossed etc.
daveboy1
24/5/2020
12:34
I have spoken to him at length 1:1 on a number of occasions and he is not quite as you describe. He certainly has lots of ideas and came up with various different scenarios when I was talking to him. Admittedly Carl was much more of a showman but maybe that is not what you want when negotiating a complex deal where you have to be a detail person to sort out all the issues the other party has.
nobbygnome
24/5/2020
12:29
My further take on him - Finance guy (different skill set), a bit wooden and uninspiring maybe to the workforce? That bloke that never comes to the pub because he's getting ready for the auditors coming etc. Hasty replacement just suggested to me a plan is already in the pipeline and perhaps he is a figurehead to bridge the gap. As ever, happy to stand corrected if he can pull the rabbit out of his WH Smith leather briefcase, instead of his chicken sandwiches that Mrs Watts made for him !!
daveboy1
24/5/2020
11:53
NG .... fair point.
peachie 74
24/5/2020
11:37
>> peachie To be fair and balanced Carl did strongly suggest that a deal would be done before the end of 2019. In private conversations with him after various presentations last year he was very confident they would deliver in that time frame. In fact maybe that is part of the reason why he has gone because he talked a good story and didn't deliver. Famously at one Priactive presentation last Summer before the approval he said he expected a quick deal because 'every day the product is not on the market in the US we are losing revenue'! Here we are almost a year later with no immediate sign of a deal.....and they are indeed losing revenue.
nobbygnome
24/5/2020
10:54
Morning Dave Fair enough. Let’s hope the Americans come in with an offer they can’t refuse ! I suppose from my naive point of view , I struggle to see how people know TW may or may not do a good job. He has no CEO experience, but surely that doesn’t mean he cannot be good at the job and excel. Most people’s judgements are I presume are being made at face value on the back of the brisk videos from Proactive investors etc. Personally I thought Frank Lampard might not be a good manager, but without experience in management he has done well ( bad analogy I know !). Behind the scenes he may be a great man manager , negotiator etc. I think he has just been judged on face value , when none of us know him. He may be useless! But also he may excel I would think the large shareholders might have an opinion ? Ewan post 3236 Lack of solid results ? Results in 2019-20..... FDA broad label approval Swiss approval Uptake by third of UK formularies H2H providing good long term results To be used moving forward Sales in Europe up 70% from 2018 I genuinely not sure what more you might want. The US deal , but that was never going to happen in 2019-2020 ?
peachie 74
24/5/2020
10:34
Morning peachie, Yes, that’s half of it. The other half (which ties in) is that Americans are, for the most part dynamic go getters who can vision what they want to happen immediately, and then plan around that. He’s not that, and a late substitute to boot. I’ve had direct experience of this in a company a relative owned and I had a stake in. Interested parties were just usurped by the Americans who came in with a knockout takeover offer that couldn’t be refused. They also made it blatantly obvious that they didn’t want anyone of the workforce from the top down as they had all their own people experienced and ready. Not saying it will go down like that here, just my direct experience. More than once as well.
daveboy1
24/5/2020
10:20
5. Conclusions Anemia is a frequent complication of patients with chronic IBD. Oral iron, including both the ferrous forms and the new ferric complexes, is effective and is recommended for the treatment of mild anemia. However, in the context of the COVID-19 health emergency, which requires maximum respect for the social-distancing rules and the reduction of nonessential hospital activities, the oral supplementation could be a suitable alternative for anemia therapy. We have learned an important lesson from the current pandemic and have provided an ambitious algorithm for the management of patients with martial-deficiency anemia, highlighting that patients can be managed at home and, only in urgent cases, in the hospital. Head-to-head comparative trials are needed to define which is the best oral iron formulation for the treatment of IBD patients with anemia. Author Contributions: S.D. and L.P.B. conceived of the study. F.D. wrote the first
peachie 74
24/5/2020
10:18
In relation to COVID...someone did ask ,, https://res.mdpi.com/d_attachment/jcm/jcm-09-01536/article_deploy/jcm-09-01536.pdf
peachie 74
24/5/2020
09:25
I was looking to top up on the drop but I'm afraid that video has put me off. So much that should sound positive but somehow highlights the lack of solid results. If it wasn't for that nice up-front from ASK, I'd be comparing this to VRS.
ewanwhose
24/5/2020
09:20
Out of interest , why is he not CEO material Dave. I have a medical , not corporate background , so have no idea Is that just your impression or based on factual knowledge about TW’s drive , ambition, negotiating skills, man management etc ?
peachie 74
24/5/2020
09:10
I’d go along with that summary, NG. My corporate experience of dealing with US ‘partners̵7; was they come along and want the whole thing, and aren’t interested in being second fiddle. I wonder if that’s the bit Carl didn’t like.
daveboy1
24/5/2020
07:40
Don't forget they have a consultancy firm helping them sort out the deal too. I don't disagree that the management is looking a little flaky and perhaps that reflects actually they are close to throwing in the towel and might just get acquired. That would be a little disappointing but I think most investors ultimately would not be unhappy with that scenario. The bottom line is that despite the negatives which we can all see, the company is fundamentally undervalued because of the asset they have which is close to being licensed....or the company getting taken over!
nobbygnome
23/5/2020
23:41
I think grief is just understandable frustration when seeing a good product mis-handled. That guy is just not CEO material, sorry. I hope it doesn't impact the deal. At least Carl is sticking around to protect his 10m shares...
daveboy1
23/5/2020
20:01
If only they could 'claim' something positive related to COVID-19 for Feraccru... the share price would fly!!
ekcs
23/5/2020
19:29
Agreed. I’ve had grief for stating positives when negatives exist. But exactly that , the negatives are the reason it’s around £1. IMO the negatives are all to be expected in business. The positives here are massive IMO as I’ve pointed out previously. Each to there own and GLA
peachie 74
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