Scancell Share Discussion Threads

[marcusl2] 19/11/2024 08:48

Last patient no.43 will be recruited next week.25 weeks, we will know about iScib+.

Scancell thinks it should be as good if not better so looking forward to those results.

For Scib-1, 80% progression-free survival (PFS) rate at six months, significantly higher than the 65% achieved with standard treatments.

Complete remission has been observed in 20% of patients, with 84% showing disease control.

Chief scientific officer Professor Lindy Durrant emphasised the importance of the PFS data, explaining that it predicts the long-term benefit for patients and will serve as the primary endpoint for the upcoming registration study.

Modi-1 some nice stable disease in some very advanced cancer patients in H&N and Renal.

7 patients now in the RCC study with Ipi/Nivo. 44 patient cohort.

Head and Neck single CPI, 3 responders in that cohort at week 9. Lindy "Modi is looking good"

[2tyke] 19/11/2024 08:48

Yep, exactly as Elliott wave expects.
Scientific progress ? That's for companies...not stocks.

[phoenixs] 19/11/2024 08:48

The problem has been, in the first instance, that two funds have been selling down throughout the year. One has been the Wood family and the other has been Calculus(redemptions etc). So good news has resulted in the selling by these two funds
There should have been a concerted effort on behalf of the company to approach the two concerns and to take out their shareholdings and place them with other interested parties.
The second problem has been the rate at which the cohorts for trials have been recruited. This could have been down to not enough suitable patients.
I do not think that funding will be the issue that some are making out. The cash runway takes the company through the third quarter 2025 and there are most probably milestone payments coming in the near future.
Finally, I think that some PIs look into the numbers and try to be the gurus of when and how good or bad the trials are going.

[nigelpm] 19/11/2024 08:36

Back to single figures then - funding clearly in the minds of folk.

[ivyspivey] 19/11/2024 07:28

Morning Ruck hope your down under visit is going well.
Nana if I had bought at 10p I would have doubled my profit.
As I said Maths is not one of your best suits in fact only surpassed by your total lack of understanding of the Science and how the industry work.
Hope the burning logs are keeping you warm and cosy Loz

[ruckrover] 18/11/2024 22:48

So what was your point about 2 year data?

[inanaco] 18/11/2024 22:30

you predicted 33p ...now be quite and wait

[ruckrover] 18/11/2024 22:28

And your point is?

[inanaco] 18/11/2024 22:22

silly boy .......

you will have two year ISCIb1 and SCIB1 data .... before you get the results from the registrational trial


this will give you DCR ORR PFS and two year OS

[ruckrover] 18/11/2024 22:21

"again i am staying out of the dilution debate"Lol

[ruckrover] 18/11/2024 22:20

Perhaps no dilution by Xmas but sometime soon. If it does come before Xmas my prediction for share price would be 11p

[inanaco] 18/11/2024 22:20

again i am staying out of the dilution debate .... its pointless and stupid so early in the cycle when you have only had a partial glimpse of the trial

even thou its great data

[ruckrover] 18/11/2024 22:18

"progression free survival ... is self explanatory"Yes, but apparently the fact you can't predict 2 year survival until you have 2 years worth of data needs to be spelled out to some.

[inanaco] 18/11/2024 22:13

its the xmas cracker this year

33p dec 31 ..... gazza

no dilution

😎

[inanaco] 18/11/2024 22:11

marcusl2 - 15 Nov 2024 - 14:46:29 - 14153 of 14465 Scancell - Pot of Gold or POS? - SCLP
23p M
30p Inan
27p Phoenixs
33p Gazza
32p miavoce
13p Loz
21p Connello
16p pharmaboy3
28p Flugelhorn
15p Nigel
29p Roger
34p Xylos
22p Plasybryn
18p MarkingTime
34p CW
10p dominoman (aka Private Frazer)
55p Moljen
30p keymosaby
45p Chilltime
48p Dom

[ruckrover] 18/11/2024 22:10

Yes, 33p WITH 100% dilution. You think only 27p without dilution.Something doesn't add up!

[inanaco] 18/11/2024 22:10

progression free survival ... is self explanatory

[ruckrover] 18/11/2024 22:09

"but some ask the question ... why would a scientist in this sector ask Chat GpT about PFS ..... ??"Even if you know the answer to something, it is sometimes useful to get different perspectives on a topic. AI can do this and merely to get an answer rephrased can be helpful.In this case, Burble wasn't asking what PFS is (he obviously knows) but was asking chatGtp to assess particular comments and Conclusions regarding PFS.

[inanaco] 18/11/2024 22:04

well i have your prediction to fall back on Gazza ... it was higher than mine

🤣 33p from memory

[ruckrover] 18/11/2024 22:01

"what you folks have missed .....we have added a Gold Standard Endpoint .."What we haven't missed is the Gold Standard pl..ker

[inanaco] 18/11/2024 21:58

Ivy you have not made £500 ... if you had of bought at 10p that would be 7 months ago

so one trade in 7 months ? so that is £500 profit

but lets try again to replace the shares you need to buy again ! and the difference is the profit

nothing has changed I own part of Scancell its not money

until i sell ...

[ruckrover] 18/11/2024 21:56

"we have all discussed how finance can be arranged but sadly its not our JOB"We have also discussed trials, patents, the science, market size, potential returns etc etc. None of which are "our job" but nonetheless important considerations for serious investors.

[ruckrover] 18/11/2024 21:50

I'm on the train to Sydney. I thought I saw a kangaroo but it was just the share price bouncing up and down!

[ivyspivey] 18/11/2024 21:49

Better to make £500 than lose £25k but then Maths was not one of your strengths.
Mind you I can’t think of any.