Scancell Share Discussion Threads

[inanaco] 08/1/2022 08:48

Fragma

Scov1 and Scov2

Both Target the "N" protein and both carry the Fc to Fc Avidmab against the "n" protein generating T cell and Antibodies against the "N" which is conserved across all coronavirus variants

the only difference is the Spike protein has bias towards different variants ...

with Scov1 targeting the original strain like current approved vaccines

and Scov2 targeting the Beta strain which can evade the immunity generated by the original strain

so SCOV2 is used to broaden the immune response of those already vaccinated I dont use the word Boost because it does not "boost" the original vaccines as no Viral particles are released to stimulate a further response to the original vaccination instead it broadens with a wider variety of antibodies and t cells generated by the vaccine

and Scov1 is used for those not vaccinated at all which is then boosted with SCOV2 to broaden the antibody response to the beta variant, and deepen the "n" protein targets

[torquayfan] 07/1/2022 23:43

AND in a similar vein :-

"Fourth Covid vaccines are not currently needed, government scientific advisers have said, amid increasing evidence that the omicron strain is much milder than previous variants. On Friday night, the Joint Committee on Vaccination and Immunisation (JCVI) announced that booster jabs continue to provide high levels of protection against severe disease from omicron in older adults, including the most vulnerable. The committee's analysis found that, three months after receiving a third jab, protection against hospitalisation among those aged 65 and over remains at around 90 per cent.

Ministers have been exploring the possibility of a fourth jab for several weeks after Israel, considered a global pioneer in Covid vaccination, launched such a programme last month. But Prof Wei Shen Lim, the JCVI's chairman of Covid immunisation, said: "The current data show the booster dose is continuing to provide high levels of protection against severe disease, even for the most vulnerable older age groups.
For this reason, the committee has concluded there is no immediate need to introduce a second booster dose, though this will continue to be reviewed." "

[panama7] 07/1/2022 23:34

Roddy, this is Moderna who have never brought a product to market before but can come up with a safe effective v a x in months when no one previously has been able to come up with a CV vax before. On a brighter note Supreme Court Judge rules Pfizer have to release trial data within 8 months not the 75 years previously sought by Pfizer and FDA.

[roddymccorley] 07/1/2022 22:43

https://www.irishtimes.com/business/health-pharma/moderna-says-another-round-of-covid-boosters-may-be-needed-in-autumn-1.4771242

[fragma] 07/1/2022 20:00

Hi inanaco, you seem to know your stuff on the the technical side of things, I was wondering if you could explain in layman's terms the difference between scov1 and scov2 and the reasoning of why the company is trialing them both ?

[emptyend] 07/1/2022 16:56

Interestingly, President Biden just answered an unplanned question re Covid at the end of his press conference re the jobs report, by indicating he wants the future to be variant-proof and they are "working on it".We'll be hearing a lot more about better vaccines quite soon, I think....

[panama7] 07/1/2022 15:19

Inane, as an avid Tory, you should be interested in extracts of a letter sent to Sir Graham Brady and the 1922 Committee recently.........

This was the time when Neil Ferguson et al, of Imperial College London, recommended suppression of 'the virus' (aka
lockdown) "until a vaccine becomes available", in their infamous Report 9. Ferguson et al's report influenced
lockdowns around the world, including Australia, where it was cited in the Doherty Institute modelling that put
Australia into lockdowns and restrictions from March 2020. Ferguson et al admitted it was uncertain their suppression
strategy would succeed long term, acknowledging that "no public health intervention with such disruptive effects on
society has been previously attempted for such a long duration of time. How populations and societies will respond
remains unclear". Did the Johnson Government seek alternative modelling to evaluate the impact of the "disruptive
effects on society"? It seems not...
It wasn't disclosed in Ferguson et al's report that Neil Ferguson was funded by the Bill & Melinda Gates Foundation,
an organisation which has dominated international vaccination policy for the past 20 years, including via the WHO,
Gavi and CEPI etc. This is a significant conflict of interest.
It was Bill Gates who led 'the race for a coronavirus vaccine' last year, see his GatesNotes: What you need to know
about the COVID-19 vaccine, 30 April 2020.
It was Bill Gates who had Boris Johnson at his beck and call for the Covid-19 vaccine rollout, also planning to
"prevent future pandemics", see: UK Prime Minister Boris Johnson meets Bill Gates to discuss COVID-19 vaccine,
WION, 12 November 2020.
It was always about 'the vaccine'...the now defective 'leaky vaccines' that don't prevent infection nor transmissio

[panama7] 07/1/2022 14:13

Great news that novak Djokovic is standing up for people's freedoms everywhere. at the same time Rafa Nadal is promoting the vaccine with photos emerging of him with arms around Bill Gates. Looks like v a x fatigue has well and truly kicked in , how on earth are Scancell going to sell another jab into arms when people are waking up Globally and are losing complete and utter trust in Big Pharma and the reps in Government and the MSM promoting the jabs. Some good news for Scancell though Cancer cases are going through the roof, the problem is with the destruction of Health systems everywhere where will Scancell get the Hospital resources from to run the trials.

[marcusl2] 07/1/2022 11:41

upfront payment of $30 million, phase 1b.

Neurimmune AG announced that it has entered into an exclusive global collaboration and license agreement with Alexion, AstraZeneca Rare Disease group, to develop NI006. This is an investigational human monoclonal antibody specifically targeting misfolded transthyretin.

[gazza] 07/1/2022 10:44

Inan,

Yes, I do understand your point.
I'm happy to use my market figures for the purpose of my investment targets.
You are happy to use the "new market" for your purposes.

That's fine. So between us we have a target of £1-£8. The bottom figure still represents a good return on the current share price

[inanaco] 07/1/2022 09:10

Gazza6 Jan '22 - 20:55 - 47880 of 47884
0 0 0
Inan,
If the "new" market for Modi is greater than Covid then great.
We were talking about the CURRENT market.

Perhaps LD should have had an extra slide showing what "might" be.


Gazza you still don't understand it ............

Moditope creates a new market ..........

so how on earth can you include it in a ""current market"" ...

when approval and Price point reflects Market value x number of potential patients

which goes no where without "Efficacy"

our covid vaccine is the same

because if its approved it creates a New Market ......... the Universal Vaccine market

[pharmaboy3] 07/1/2022 05:11

Vulpes share activity upto end 2021HTTp://www.investorease.com/xcompany.php?disp=major&epic=PRM&holder=Vulpes%20Life%20Sciences%20Fund

[gazza] 06/1/2022 20:55

Inan, If the "new" market for Modi is greater than Covid then great. We were talking about the CURRENT market. Perhaps LD should have had an extra slide showing what "might" be.

[inanaco] 06/1/2022 19:45

simple speak

"universal Vaccine" creates a "NEW Market"

Moditope "Creates a New Market" ............ and it will be far bigger than Covid

[inanaco] 06/1/2022 19:32

you missed the point with moditope it has no market to enter ...

its a "new Market" generated by folks that didn't die

the Covid market is huge you only have to look at BioNtechs balance sheet

however ... again it was not a "market" before because it was not there ... so it became a ""new market size""

point being the market size is dictated by efficacy which is what i have been blabbing on about for years ...

its not about market share .... its about who has the best efficacy so even thou AZN was one of the first and it was cheap ... it still didn't win the race

you always go on about "Market Share" in all your posts .... Gazza

you are looking at it the wrong way ...

1/ is Efficacy which is why i refrain from "inflated values" £8 is achievable

all we are looking for is "n" antigen responders being above 55% coupled with High Avidity ..

its a new market ...... "universal vaccine is in play"

then you will know just how valuable scancell really is ....

[inanaco] 06/1/2022 15:49

Gazza

your figures are not Scancells ....... ?


EE did not say that at all that the numbers matched yours


emptyend6 Jan '22 - 12:31 - 47870 of 47875
0 4 0
See slide 21 in AGM presentation. The market for the 5 categories of cancer vaccines in which Scancell is developing products is expected to roughly double over the next four years to nearly $100bn, but the portion addressed by Modi is only about 5% of that total.

[gazza] 06/1/2022 15:17

Inan,

Well, as pointed out by EE, the figures are from Scancell's own AGM presentation.
Obviously LD has more scruples regarding misleading the market than you do.

[gazza] 06/1/2022 14:34

marcus,

Very happy to discuss Scancell - still awaiting your response to my previous question.

[marcusl2] 06/1/2022 12:42

I don`t know why some of you don`t use the filter button as I do. Concentrate on the people who actually talk about Scancell. It makes for a much more pleasant experience.