Scancell Share Discussion Threads

[emptyend] 03/2/2021 08:58

Correct, Chillpill. Bizarre market response to this "news"....

[notknowing] 03/2/2021 08:54

Every ADVFN thread needs an inanaco!

Cheers buddy.

[inanaco] 03/2/2021 08:50

I think folks forget that all the preclinical was funded by CRUK basically we just got back a freebie ...

a fully developed liposome nanoparticle delivery system

scancell will have been involved for sure so the technology developed for immunobody is secure

however to get the chance to upgrade to avidmab before manufacture and indeed to potentially shift to nano protein delivery with all of the benefits that may bring is well worth the further investment

for a start it comes with a brand new patent .... commercially "very high value"

[chillpill] 03/2/2021 08:49

Just looking at research from last year:

As a final point, investors will notice the absence of SCIB2 within our discussion so far, which resides within Cancer Research UK (CRUK). It will have passed few investors by that the funding environment for charities has suffered significantly during the coronavirus pandemic and CRUK has not been alone in this regard. We presently do not expect CRUK to be resourced to advance SCIB2 alone and there are a number of options under consideration which could, potentially, include co-development or the return of the asset to Scancell.

[inanaco] 03/2/2021 08:40

also read fully the 1/2 year RNS get a feel for whats planned this year

Scancell is sitting on a huge cash pile

[volsung] 03/2/2021 08:39

Bought a few more at 12.77p

[inanaco] 03/2/2021 08:38

well done

u got a cheap share hold it for min 12 months and watch

[notknowing] 03/2/2021 08:37

Bought 18k worth.

General Public 5.4% (I bet most of that is us on here).

Staff numbers increasing.

Looks positive. Right solutions at the right time.

[inanaco] 03/2/2021 08:36

Notknowing

every time we see a dip ... Diggles piles in ..he holds about 92 million

you only have to read what is planned this year to understand that Scancell is one of those stocks that contains magic ..

Look at the patents

[chillpill] 03/2/2021 08:32

Goosed- only ever posted on SCLP- bitter ex-employee?

A few cranky people on this thread!:)

[notknowing] 03/2/2021 08:28

I have 18k available (sold BOOM). Worth buying here on the dip?

[gooosed] 03/2/2021 08:27

Yet another appalling RNS from Holloway.....no account of where the development of SCIB2 actually is & where any prospective collaborative partner (don't hold your breath) would be expected to take up from.

This was the last meaningful update as brief as it was :

"We are delighted to announce this important milestone in our partnership with Cancer Research UK, which moves us one step closer to entering the clinic. This new nanoparticle approach to deliver SCIB2 is expected to achieve results that are as effective as, or even better than, electroporation. We believe SCIB2 has the potential to provide a much-needed treatment option for patients suffering from a range of common solid tumours including NSCLC, the most frequent cause of cancer death globally."



My undersatanding is that much of the assessment of alternative delivery method for SCIB2 was done by Scancell prior to handing over to CRUK. In essence Holloway has ducked the issue again & since Dec 2017 there's been no real advance in SCIB2.



Not acceptable from a CEO that moved so swiftly to increase his own salary but provides very little in return. Goy - yes a charisma bypass but I suspect there are other "co-morbid complications".

[emptyend] 03/2/2021 08:17

Fundamentally no surprise here. CRUK are clearly under massive pressure, as all their releases and fundraising comments have indicated.It may be that the agreement over SCIB2 imposed more onerous obligations on them than some others, therefore making it a candidate for termination. For any corporate buyer, the situation is now a little cleaner.

[miavoce] 03/2/2021 08:10

Maybe My Diggle will take the opportunity to grab another 500k or so.

[plasybryn] 03/2/2021 08:09

Human nature. Buying opportunity for those more savvy perhaps

[miavoce] 03/2/2021 08:09

Indeed, hopefully this MM overreaction has created a good buying opportunity that some can take advantage of.

[chillpill] 03/2/2021 08:06

Strange reaction!

[inanaco] 03/2/2021 08:04

Just cannot believe what Burble is posting, he is so distanced from his understanding of Scancell its a bit of a worry, I can understand Tf not being on the ball as he is preoccupied with Boris ..and masks etc ... ref his post ..

I guess Burble never understood the Ichor issue and why Scancell and CRUK went liposomal nanoparticle



Pre-clinical studies have demonstrated that administration of SCIB2 as a liposomal nanoparticle results in
potent immune responses and prolonged survival. The nanoparticle technology utilises known lipid carriers
that are optimised to deliver SCIB2 DNA to immune cells. The liposomal nanoparticles protect the DNA from
degradation and facilitate efficient uptake, expression and T-cell activation against cancer cells. The
nanoparticle delivery system provides an alternative approach to electroporation, which has been used to
deliver other ImmunoBody® agents to patients. Cancer Research UK are now planning a clinical trial to
investigate the safety and efficacy of the SCIB2-nanoparticle complex in patients with solid tumours.

[miavoce] 03/2/2021 08:03

Given that SCIB2 has spent years going nowhere with CRUC this is good news. I expect the price will recover pretty quickly.

[oldnotwise] 03/2/2021 08:01

13ind/13
Great RNS!!!! :-(

[chillpill] 03/2/2021 07:21

It’s been telegraphed by the company since the placing 6 months ago and now they are fully funded for 3 years is a lucky break for them as it means they can accelerate the program.

[inanaco] 03/2/2021 07:11

Excellent news ........... Scib2 back in house and potentially will get the upgrade

with Avidmab, "Covidity" seems now to be the lead product, the resultant immune response will give us a good idea on just how effective Avidmab/immunobody will be ...

[torquayfan] 03/2/2021 00:18

A 'Nature' briefing - it's always good news to hear positive comments about vaccines - even Sputnik V ! Some discussion about this on R4 and the possibility of dosing Sputnik V after a first dose of say Oxford/AZ - there's a long way to go on that discussion I suspect.

"Russian vaccine has 91.6% efficacy

Peer-reviewed data show that the Russian COVID vaccine called Sputnik V is safe and that it works. The randomized, placebo-controlled phase III trials, done at 25 hospitals and clinics in Moscow, Russia, included almost 22,000 people. The vaccine showed 91.6% efficacy. In a move criticized by many scientists as reckless, Russian regulators licensed the vaccine for limited rollout in August, without waiting for safety or efficacy data from a phase III trial. It is already in use in several countries, including the United Arab Emirates and Iran."

I can't seem to link it here - anyone ? Otherwise it's there on LSE . .

[torquayfan] 03/2/2021 00:14

Thanks Chillpill. Can you link that Panmure Gordon comment ? Are they up to date ?

[chillpill] 02/2/2021 23:17

PG are saying they hope to start the SCIB1 Phase 2 late in Q1 which is great news.

...Obviously subject to Covid