Tom Barnaby is no longer 'with us'. |
I am a SCLP holder, have been for a long time. I did create this thread because you dominated the previous thread and yet you followed..... what does that 'say'. |
oh come on Dom you have your Own "Extreme Right Wing sites" .. to express your views ... nobody posts on them and you don't post anyway ...
what are you getting away from ?
Clicking this thread and viewing .... ???
but the reality, its NOT your thread and your Mate, clearly was not your mate !
so i would not bragg to much ... considering |
 French Military ....
It was supposed to be the showpiece of Nato’s support for the war in Ukraine – the first of 14 almost entirely Western-trained and equipped brigades that would push back the advancing Russian army.
In reality, the 155th Separate Mechanised Brigade was, in the words of one Ukrainian war correspondent, “from its first days, complete organisational chaos”.
Announced during D-Day commemorations in Normandy last June by Emmanuel Macron, the brigade was given the finest French military instructors and weaponry at a cost of more than €900 million.
But before the 155th ever fired a shot in anger, it was dogged with scandals and claims of rampant mismanagement. At least 1,700 troops had gone AWOL, including dozens in France, its commander had been fired, and it was fast becoming a major headache for both Volodymyr Zelensky and Macron.
Now, the 155th – also known as the “Anne of Kyiv” brigade after the 11th century Kyiv princess who became a French queen – has disintegrated, with its few combat-ready troops sent to reinforce other units.
The shambolic formation of the 155th was enough for Mr Zelensky to pull the plug on any future Western-sponsored brigades.
Telegraph
France
I feel the weather forecast is coming .. |
Oh well...can't fault your devotion to the cause.... . Sci....you do seem a bit on the aggressive side...lol |
I can smell the BO from here. Jeez. |
No ... i have another £1000 ready ..🤣🤣🤣🤣129315; |
"Search me..."
Get a room already. And Nana, you are the most PATHETIC person that ever existed on this planet,.Start a thread of your own and then see who follows you, instead of hijacking multiple public threads and pretending everyone worships you. Start a new thread and talk to your followers there (which according to you is almost everyone) if your wrinkly moldy @@s have it in them. |
what is "only intellect" |
One thing you defo can't do is talk like tykey ! You haven't the only intellect, honesty or capacity. . Yes, there are parallels between trump and this resident idiot. . The risk in this stock is 'massive' And ...the stock market is ALWAYS GAMBLING |
Lindy we have Great t cells Moditope
same game is now play ............
ATB |
looks like 2015 copyright
still in play
🤣🤣129315;🤣9315;🤣 |
AI Overview Learn more Cellular-level interactions that lead to the cytokine storm ... A cytokine storm is a condition where the body produces too many inflammatory signaling molecules, called cytokines. This can lead to serious symptoms, including organ failure and death. Symptoms confusion, shortness of breath, and lethargy. Causes A cytokine storm is a pathological reaction that occurs when the innate immune system releases too many cytokines. Treatment Cytokine storms can cause serious symptoms, including organ failure and death. Other names Cytokine storm is also known as hypercytokinemia. |
which is why when you treat with
Pd-1 ctl-4 system
you are taking the brakes off .........................
its systemic and toxic |
and if the immune system did not have "calm me down boys"
your dead in 10 hrs
Sepsis is a life-threatening condition that occurs when the body's immune system overreacts to an infection. It can damage organs and tissues, and can lead to septic shock, organ failure, and death. |
it then moves on again ....
because a powerful t cell response is also bad for you the Cytokines
so the immune system then adds another layer "t regs" Mr Calm me down boys
Pd-1 ctl-4 system is designed to calm this system down as well
and MDSC's
problem Cancer Hijacks all of it ................
the escape Phase |
now to stop the reactive t cells going active you still have HLA and a two signal activation
but we still get auto immune issue ..
so a bacteria or any foreign antigen can look like self and trick that reactive t cell
into going live ...
this is why Powerful T cells can be very dangerous if the vaccine is poorly targeted |
mutant t cell that has escaped the thymus .... runs the risk of Auto Immune disease
the thymus is trying to protect self by deleting High Avidity they are very reactive
cancer has escaped the immune system so you need a boosted t cell
the thymus has deleted all your Reactive t cells ...
which is way cancer vaccines became so complicated
you need those reactive potent t cells to go after cancer |
you see Ruck its not Black and White ... |
 your cancer is there .............
your immune system is there
How many natural High Avidity t cells do you have circulating against the cancer ?
very few and they are mutants ...
Results: CT83 reactive T cells from young healthy donors (YHDs) were generated by repeated stimulation with DCs and peptides. The single-cell TCR sequencing results of reactive T cells indicated that a single TCR clonotype dominated the paired TCRs. T cells engineered with this dominant TCR led to HLA-A*11:01-restricted recognition of the CT8314-22 epitope, with higher avidity. Functional assays showed powerful cytotoxicity in vitro against the targets of several CT83-positive solid cancer cell lines. Furthermore, TCR-Ts showed therapeutic efficacy in three xenograft solid tumor models. The meta-analysis of gene expression of 92 CTAs indicated that most CTAs did not or at low levels in the thymus, which suggested that those CTAs may experience incomplete thymic central tolerance.
"""incomplete thymic central tolerance."""" |
now also the data you presented to show avidity was against a Virus
you will have memory of previous infections of Coronavirus
how many of those T cells came from "previous infections" ?
reinvigorated by the vaccine
answers on a postcard will suffice Mr Data Scientist |
yes i did Ruck .... as i have explained the thymus limits avidity close to the limit, t cells still get through at the limit
i have also explained culturing changes avidity ...
I have also explained Low avidity prevents massive clonal expansion by high avidity and competes for the target
scancell induces High Avidity ... a huge difference
what your head is unable to do is accept that ...
not my problem !!!!!!!!!!!!!!!!!!! |