Lloyds Banking Share Discussion Threads

[xxxxxy] 18/8/2020 12:29

Boycott goods and products of the EUSSR. Particularly Boycott goods and products of France.No DealWTO

[xxxxxy] 18/8/2020 12:28

It's time to declare the EU in default of their own Withdrawal Agreement (WA)Above is an example of €3bn of EU money being borrowed and disbursed, with the UK taxpayer likely to be liable, and without Boris Johnson even being allowed to be present at the EU Council meeting of 25 May 2020 where this was decided.

[minerve 2] 18/8/2020 12:28

Alphorn, thought you might like the video (Biden plus nice car)

[buywell3] 18/8/2020 09:20

wobble wobble

US CEOs are selling stock. That could be a bad sign for the epic market rally
Aug 17 4:35pm:

[xxxxxy] 18/8/2020 09:16

Time...The UK and the EU need to complete a deal by the end of October to ensure both parliaments to have enough time to approve a deal and give businesses some much needed clarity... Daily Express... No Deal. Happy Times. WTO

[geckotheglorious] 18/8/2020 09:12

Maxk,
Post 312651

Do none of these idiots have any sodding common sense?

It's all taking offence / seeing waycism drivel

Common sense has left the building and we will all be worse for it.

[geckotheglorious] 18/8/2020 09:10

Within 28 days of being Positive makes sense...but omitting deaths at care homes/residential homes does not.

[geckotheglorious] 18/8/2020 09:08

England and Germany neck-and-neck in race to produce first vaccine
Both products have completed successful phase one and two trials, with data suggesting they produced a 'robust' immune response- antibodies and T-cells-in volunteers after two doses.

Experts say the result is too close to call but will be decided by evidence and data, not penalties
The race to produce the first fully licenced vaccine to protect against the new coronavirus may come down to a playoff between teams in England and Germany.

Kate Bingham, chair of the UK Vaccine Taskforce, the body in charge of the UK’s vaccine strategy, said on Monday that two groups-one in Oxford and one in Mainz, Germany-were running head to head and may yet see their immunisations approved before the end of December.

“I think we have a shot of getting a vaccine this year,” Ms Bingham told Sky News. “There's two potential candidates, one would be the Oxford candidate and the other one is the German vaccine from BioNTech.”

These candidates are among six the UK has already ordered (with a total of 340 million doses) as a means of hedging its bets against candidates returning poor data in phase three trials.

Ms Bingham said she was “very optimistic” about all six vaccines, which use four different technologies to fight Sars-Cov-2. She said early results from three were encouraging but singled out the Oxford and German teams as the most advanced.

“Those are the two that, if everything works, could potentially be both registered and delivered this year,” she said, with the caveat that “it is most likely to be next year, though.”

While the Oxford vaccine has received huge media coverage, the candidate being trialled by the German biotech company BioNTech has attracted fewer headlines.

Unlike the Oxford candidate, which requires a conventional manufacturing process, the German vaccine is an mRNA-based product. If proven to work, it can be synthesised in a laboratory at greater speed-a major advantage when almost eight billion people across the globe may need a jab.

It’s a platform Thomas Strüngmann, BioNTech’s biggest shareholder, has claimed could make it “the Amazon of vaccines”.

Both products have completed successful phase one and two trials, with data suggesting they produced a “robust” immune response- antibodies and T-cells-in volunteers after two doses.

The teams are now conducting phase three trials in which tens of thousands of people in multiple locations around the world receive the jabs to demonstrate their safety at scale and their ability-not just to provoke an immune response-but to protect against the virus.

Dr Nick Jackson, head of programmes and technology at the Coalition for Epidemic Preparedness Innovations (Cepi), said one of the “distinct advantages” that both teams had was partnerships with big pharmaceutical businesses-something that had enabled them to scale up fast.

While the UK team is backed by the pharmaceutical giant AstraZeneca, the German team is supported by Pfizer. Governments across the globe have already signed contracts with both companies for billions of doses.

But buying a prospective vaccine is one thing, buying one that works is quite another. Although there is rising excitement about the race and scientific optimism a protective vaccine will eventually be found, many experts are still advising caution-historically as many as 35 per cent prove unsuccessful in phase three trials.

Some may not work at all and while some may protect against the most severe coronavirus symptoms of Covid-19, they may not prevent transmission of the virus, warned Dr Jackson.

It is also unclear how long any protective effect will last and early trials have focused on healthy individuals between the ages of 18-55, meaning it is still unclear if vaccines will trigger an immune response in older, more vulnerable groups.

Beate Kampmann, director of the Vaccine Centre at the London School of Hygiene and Tropical Medicine, is dubious about whether the Oxford or German vaccines will be available by the end of the year.

“They might have their phase three results [but] that’s all that can be said. I think, to use the word 'ready', is actually misleading,” she told The Telegraph, pointing to the considerable logistical hurdles around manufacturing and distribution.

Prof Kampmann added that the “assays they use are not directly comparable”, making side-by-side comparisons of the Oxford and German candidates less clear-cut.

“The trials we need is head-to-head comparisons and analysis with the same methodology in the labs, but no one wants to do this at the moment,” she said.

Of course these two vaccines are not alone in the race. There are four others in the UK portfolio, including two American candidates from Moderna and Novavax.

Meanwhile in China several vaccines are deep into human clinical trials-including the CanSino jab, which has already been given to the Chinese army and many travelling executives as part of phase three trials.

More controversial is Russia's “Sputnik V” vaccine. According to the Russian government, mass-vaccination will begin come October-yet the jab is yet to enter phase three trials.

“No regulator in the West would approve a vaccine that's only been trialled on 38 people,” Ms Bingham said when asked about the jab. “That doesn't prove whether it's safe or effective. It may be both, but on the back of 38 people you can't tell.”

Dr Jackson welcomed the race between Oxford and BioNtech but said he hoped for several victors. “It is a race in the sense that we need to go fast, but it's a race that needs multiple winners.

“It's only [with] several successful vaccines licenced in the UK [and] around the world that we're going to be able to deal with this pandemic. We need very large volumes and vaccines of different profiles for use around the world.”

Asked how close the Oxford versus BioNtech game might be, Dr Jackson said: “Will it go to penalties? No, I’m pleased to say it will be decided on evidence and data.”

[suehannah1] 18/8/2020 08:54

Originally anyone who died and has had Covid was registered as a Covid death - even if you got hit by a bus 3 months after you had the virus. They now only register the death as Covid caused if it occurs within 28 days of the positive test or definite link between the death and Covid. More sensible, no conspiracy.

[utrickytrees] 18/8/2020 08:39

Smashed..... fornicated with in the rough manner.

[geckotheglorious] 18/8/2020 08:29

Cheshire,
Yep,live outside of the City. Detest London these days. Not the same as it used to be when I lived there in the 80's/90's

[joe say] 18/8/2020 08:20

Nimby mentality - that's why we're in this mess

[optomistic] 18/8/2020 08:12

mitchy, apparently they now only record certain deaths, I think the care home and hospital deaths are omitted. Would like this to be confirmed by someone but it's in my mind I saw that reported a few days ago.
If it is so then it's another one of those dishonest moves from the government.

[cheshire pete] 18/8/2020 08:10

Couldn't agree more Gecko....sadly I don't think it will happen. I try and ignore these things otherwise it could be depressing. Just glad that we live out in the sticks and don't see too much of the fall out...except on TV that is.

[geckotheglorious] 18/8/2020 07:50

maxk
Post 312625
"Why are the Conservatives determined to drive their natural supporters to revolt?



Because they are not proper Conservatives.
For a start they are weak on social values. Ditto immigration.

Illegals need to be deported, not brought to UK shores but returned to France.
Illegals, some 1million+ already residing here need to be returned to country of ethnic origin.
Criminals need to be flattened, law & order returned to London for example.