Creo Medical Share Discussion Threads

[dr biotech] 12/3/2024 13:27

From about 16mins. The whole thing is quite interesting though - he really believes in the tech.

For your video I found the part from around 6mins to be most interesting, he talks about alternative sources of funding.

[innnovate] 12/3/2024 13:25

I filled out a form to register as a stakeholder in the NICE process. As such you receive updates on progress and have access to documents. Let’s see if they accept the application.

[hatfullofsky] 12/3/2024 13:05

This one Dr B ?

On 7min the interviewer asks for next 6 months milestones, Gulliford corrects him and says 6 - 12 months and then DOES NOT mention NICE.

[dr biotech] 12/3/2024 12:55

The CTO said "6 months" in a proactive presentation in Jan. I watched the whole of that one, he didn't seem particularly plugged in to the commercial side and it was a fairly casual comment. Very good from a tech point of view though, for those that want to try and understand what they have.

[hatfullofsky] 12/3/2024 12:45

I'm confident your estimations are wrong .....In a good way ?

[hatfullofsky] 12/3/2024 12:43

Yes I would have expected it to at least have moved to - in development.In this investormeet presentation from 12/09/23 https://www.investormeetcompany.com/meetings/investor-presentation-42113min 30s "NICE Guidance 6 - 12 months in the outside, particularly good for the business"So back in September Gulliford was expecting a March - September 24 timeline

[innnovate] 12/3/2024 12:20

The company will have little influence over NICE timings. All it can do is provide high quality information in a timely manner.
From the broader NICE database (ie including pharmaceuticals) it appears that some applications predating that of Speedboat for lower GI ESD, remain at the starting gate, while others have progressed, suggesting an overstretched NICE may be prioritizing based anticipated benefits to NHS. Within the MTEP category, all 6 technologies selected by NICE for evaluation remain at the ‘awaiting development’ stage. One MTEP application (07MAR2023) pre-dates speedboat (25MAY2023).
It could be a while yet before NICE guidance is generated for Speedboat.

[pacsltd] 12/3/2024 11:16

Is that 1,000,000 shares deal a buy or sell? Anyone know?

[master investor] 12/3/2024 10:26

I'm confident your estimations are wrong

[dr biotech] 12/3/2024 09:45

That is disappointing - assuming the website it accurate (and there is no obvious reason to doubt it). Please let us know what they say. I'd hope the delay is on the NICE side.

[pacsltd] 12/3/2024 08:32

"A Complete failure from the company" !!!
Have you any idea how incompetent the NHS/NICE people really are ?!
How many NICE applications have you managed to attain?

[hatfullofsky] 12/3/2024 08:29

I've had to re-asses my timeline on NICE



CREO is still at - Awaiting Development (since 25/05/23)

According to



I'm estimating we could be up to 30 weeks away which would be incredibly disappointing and a complete failure from the company.

In Development Wk 8
In Consultation Wk 24
Published Wk 38

I'll also contact the company

@Innovate - Can you validate this please

[innnovate] 09/3/2024 11:42

Yes big volumes with price holding up thus far.
From limited access to trade log I see a large 3.5m sell late Friday.
‘08Mar-24 16:54:49 37.00 3,550,000 Sell’

[hatfullofsky] 09/3/2024 01:01

Now what about this current volume ? NICE volume ? ;-)

[hatfullofsky] 09/3/2024 01:01

It was on a video shortly after the announcement, I'll dig it out

[innnovate] 07/3/2024 13:50

@hat: re NICE approached CREO
Do you have a reference for this?
My understanding is that NICE selected Creo tech for an in depth review, but Creo will have first submitted data package describing lower-GI ESD use case for initial high-level assessment at NICE (see release of 01.06.2023). Not every application received by NICE will be reviewed in depth. I’m optimistic NICE will conclude positively, but it might easily ask for more data if the review panel is not fully convinced.

[billthebank] 07/3/2024 11:55

Canaccird selling ? Reason for pruce still being supressed?

[hatfullofsky] 07/3/2024 11:02

NICE approached CREO, that says it all

[bloomberg2] 06/3/2024 20:02

Some big trades this afternoon! Buys or sells ! Or seller finally cleaned out

[innnovate] 06/3/2024 11:52

NICE is a non-trivial process. There are examples of drugs that pass the regulator (HMRA in the UK) but repeatedly fail at the NICE hurdle eg JNJs Spravato. Spravato sells well in the US (where healthcare economics is less of an issue) but cannot be delivered in the UK via the NHS because NICE twice gave the thumbs down. NICE approval is recognised internationally as a high bar, so helpful in other markets too.

[dr biotech] 06/3/2024 10:08

That has to be the ultimate goal - have the treatment at the same time as the diagnostic. I think the penny may have dropped with some after last weeks announcement. Some have said they "loved the tech" but clearly demonstrated that they didn't have a clue what it actually does.

I don't think NICE approval for speedboat is a given. I'm not sure if they have a sufficient volume of evidence yet - although the update from the Oldham hospital last year will help. I think they can show the cost saving is significant - whether the treatment is statically better or at least equivalent may be harder. I guess it will depend on what sort of numbers NICE needs. I'd expect the hurdle to be much lower than than getting FDA/EMEA drug approval (which is an area I am much more familiar with). But the company have sounded confident and thats what I'll go on.

More on MTG decisions can be found here

hxxps://www.nice.org.uk/About/What-we-do/Our-Programmes/NICE-guidance/NICE-medical-technologies-guidance

[innnovate] 06/3/2024 08:55

Re theranostics: in the broader sense of conjoining diagnostics and therapy in a single procedure/service - Creo tech can be a part of a combined diagnostic/therapy solution as shown by Brompton.

[lawson27] 06/3/2024 08:46

Joined you @36 for the recovery here, like the tech, good sector for 2024 imo, GLA

[hatfullofsky] 05/3/2024 22:23

Massive buys reported late, I think the NICE indication is not far away