Amryt Pharma Share Discussion Threads

[greendragon777] 24/1/2018 12:55

I am more bullish for the reasons he mentioned rather than bearish!

Placings - Placing more like it, there was only one and I see it as a good thing keeping the company well funded for the foreseeable future in case the markets suddenly dry up due to a crash etc

Director Options - Perfectly normal, would you rather the directors weren't incentivized?

Muted response to today's news - It's kinda bread and butter news in a sense, it doesn't actually make a positive outcome of the AP101 trials any more or less likely by appointing her.


All that said, we'll be more bearish than anyone here with a negative trial reading.......but for now we're still bulls! :-)

[papillon] 24/1/2018 12:34

Saw this bearish post just now on the lse bb. Whether he's a genuine bear, or not, I don't know. Make up your own mind.

TrekMadone
Posts: 245
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Price: 20.25
RE: Fastnet oil and gas bare trust Today 09:11 Done some more research here. After some of the placings, director options and muted response to today£s news, Not comfortable. Good luck to holders here. Trek.

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I don't agree with these bearish sentiments. I'm still VERY BULLISH. Only time will tell who's right.

[greendragon777] 24/1/2018 11:17

I agree Pottermagic....there's no mention of 'if' the results are successful,it's more like 'when' 😁

Jeez, these interims just can't come out soon enough! 🙈

[pottermagic2310] 24/1/2018 10:40

"[... we plan for completion of our ongoing AP101 Phase III trial in EB, followed by submission to the regulatory agencies.]"

Plan for completion
Submission to...

I like the +ve intent to these statements.

[greendragon777] 24/1/2018 10:28

All sells again today Paps but price holding firm.

Thanks for posting Digadee. It's a sign of confidence of a positive outcome for AP101 trial results if they are hiring her. Doesn't mean it is going to be successful obviously. They are gearing up though!

[digadee] 24/1/2018 08:44

AIM: AMYTESM: AYP Amryt Pharma plc("Amryt" or the "Company") Senior Management Team Appointment Amryt, a biopharmaceutical company focused on rare and orphan diseases, is pleased to announce the appointment of Derval O'Carroll as Head of Regulatory Affairs. Derval has over 25 years' experience in pharmaceutical industry regulatory affairs. Prior to joining Amryt, Derval was Senior Director of Regulatory Affairs for the NASDAQ-listed rare diseases company Retrophin Inc., where she provided regulatory, strategic and operational input to product teams managing Retrophin's development-stage and commercial products. Before that, Derval worked for 11 years as a Managing Consultant at Real Regulatory Ltd, a consultancy specialising in European regulatory affairs, quality management systems and supply chain operations compliance. As Amryt continues its pivotal Phase III trial, EASE, to assess the efficacy of AP101 in Epidermolysis bullosa ("EB"), the rare genetic skin disorder, Derval will assume responsibility for engagement with regulatory agencies. In addition, she will examine opportunities to pursue new orphan indications for AP101 and AP102. Derval has an MBA, as well as an M.Sc. in Biochemistry from University College Dublin. Dr. Joe Wiley, Chief Executive Officer of Amryt Pharma, said: "We are delighted to further strengthen our senior management team with the appointment of Derval O'Carroll as Head of Regulatory Affairs. The quality of our interactions with regulatory agencies globally is a key driver of our success as we move our products through their lifecycle, and we are therefore very pleased to have someone of Derval's experience joining the team. "Derval's expertise will be particularly valuable as we plan for completion of our ongoing AP101 Phase III trial in EB, followed by submission to the regulatory agencies. As part of the overall strategy to add value to our development projects, Derval will also explore opportunities to pursue new orphan indications for our AP101 and AP102 products."  

[papillon] 22/1/2018 13:32

Saw this on the lse bb today:

Gassy
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Price: 20.40
Fastnet oil and gas bare trust Today 08:09 As part of my legacy holding in Amryt, I also hold Fastnet trust units. Does anyone know how does relate to Sound Energy£s activities - does the trust hold any Tendrara option or royalty rights?

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The short answer is, NO. The trust fund set up only holds the rights to 3-D seismic in the Celtic Sea, offshore Ireland. I very much doubt if it will prove to have any value to a third party before the trust fund is wound up.

[papillon] 22/1/2018 12:12

Many thanks for your post, greendragon, but cryptocurrencies are not for me. I wish you ATB with them.

[ny boy] 22/1/2018 10:07

Tks a lot Paps..I have these on my watchlist

[greendragon777] 21/1/2018 23:28

Thanks for the link Paps. Nothing really new in there but he is obviously an ETH fanboy which is fair enough. I totally agree that it's 10 times better than Bitcoin technology wise. There's been talk among the IOTA community about the 'flippening' for several months but I think it could potentially take a couple of years for it to happen. But when we talk about the 'flippening' we are referring to Bitcoin flippening to IOTA (yes we're a little bit biased! haha)

Bitcoin is still heading towards adopting the lightening network which will speed up the transaction times considerably but it's gonna be a messy process to get there (miners vested interest etc). I pretty much have only bought Bitcoin as a means of FIAT to Crypto conversion and that's been for a maximum of a day or two while transferring to various exchanges etc.

That said, for now Bitcoin remains the leader in Crypto and is still seen as the 'digital gold' of Cryptos. It could very well take off again in another bull run but it could also come crashing down if 'the flippening' were to really kick in. Most alt coins follow it's moving up or down though and it will probably stay like that for the forseeable future.

I'm defo not in love with Bitcoin but I'm absolutely in love with Cryptos and it's technology and future capability.

For a bit of fun Paps, try downloading the IOTA light wallet from Github (just google 'IOTA light wallet Github' and it will be the top result) and install the relevant version on your desktop (ie- select the .exe if you are using windows).

Once installed you just need to literally make up an 81 character password (using letters and only the number 9 for any numericals). Then simply generate a receive address once you are connected and advise me of what it is and I will send you some IOTAs. You will then hold your first bit of Crypto! :-)

That will save you all the hassle of opening up accounts and converting FIAT etc. Do it for a bit of fun, it won't cost you a dime and it may spark a bit of interest in Cryptos if nothing else! :-)

Sorry for the O/T post folks......we're only doing this while we're waiting for AMYT to go POP! haha


PS- I forgot to mention you will need to attach your receive address to the tangle first before it will generate a receive address for you. It might all sound complicated but once you do it once it will all start to make sense!

[papillon] 21/1/2018 23:00

"We are at an exciting stage with AP101, our treatment for EB, a rare and distressing skin disorder which causes exceptionally fragile skin. Our Phase III clinical trial for AP101 is ongoing, with an interim read out due in H1 2018. In anticipation of its successful outcome and subsequent approval, this new money will contribute to funding the pre-launch costs and the expansion of our manufacturing capacity in readiness for the commercial launch of the treatment."

The above is from the RNS dated 24/9/17. So any time between tomorrow and the 31st May, NY Boy. diamondstar, a knowledgable poster, reckons not later than 31st March.

diamondstar1 13 Jan '18 - 08:34 - 2029 of 2059

Greendragon... With the EASE Ph III trial having a primary completion date ie full recruitment of patients in Sept 2018, it is very unlikely that interim results will come out in May 2018. More likely, this will be in Q1 2018, but we will just have to wait and see!

[ny boy] 21/1/2018 22:34

How long a time frame before FDA news ?

Tks in advance

[papillon] 21/1/2018 21:46

O/T. Thought you might like this link, greendragon:

[papillon] 20/1/2018 16:24

Well it looks like Jacksonpollack is not going to get his chance to buy back into AMYT in the low teens before the EASE interim trial update. What a shame! LOL.

[papillon] 19/1/2018 18:17

There are still large sellers around, greendragon, keeping the share price moving horizontally and hence those Bollinger Bands very tight. There was another 100,000 sell @ 20.10p reported (delayed reporting) just after the market closed tonight

[bazworth] 19/1/2018 18:06

greendragon777

I topped-up quite significantly of late increasing by 50%. I have enough for what I need!! Fingers firmly crossed!!

[greendragon777] 19/1/2018 17:32

Go for it Bazworth, you know you want to....this is the last of the January sales @ 50% off! Haha

[papillon] 19/1/2018 17:15

Seen today on the lse bb:

boomorbust
Posts: 9,448
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Price: 20.25
AMYT Today 16:17 Interview with Joe Wiley in the Pharma Times

[bazworth] 19/1/2018 15:08

Don’t tempt me!!!

[greendragon777] 19/1/2018 14:56

Haha.....I hear ya Paps, I'm getting down to my last coppers at this stage! 😂😂😂

[papillon] 19/1/2018 14:33

"Are you tempted to top up even more?" Yes, greendragon. I'll have to start searching down the back of the sofa to find some spare cash! LOL.

[greendragon777] 19/1/2018 14:24

Nice one Paps, they are decent volumes and the day isn't over yet.....could end up being a good bit higher. The next RNS should be interesting! 😃

Are you tempted to top up even more? 😁

[papillon] 19/1/2018 13:51

Things are hotting up on the volume front. Another 100,000 buy @ full ask of 20.25p just reported (reporting delayed by an hour). I think we must be close to news.

[papillon] 19/1/2018 12:28

4 big trades this morning. 3 buys @ full asking price of 20.50p (123,632, 100,000 & 99,400) and 1 sell at 20.10p (150,000). Interest in AMYT is picking up? News soon?

Those Bollinger Bands are very tight because the share price is going horizontally. Big breakout on news is likely.