Scancell Share Discussion Threads

[marcusl2] 29/5/2023 11:40

no real side-effects,Modi-1, created by Scancell ,tumour has shrunk 55%. Head and neck,renal ,breast,ovarian cancers




(looking forward to the next ModiFy update)

[panama7] 28/5/2023 08:50

I wonder if the suppression of Cancer treatments will be mentioned at the Historic Disclosure Conference in Washington from June 10-12.

[golcheja] 27/5/2023 17:44

Re covid, complete waste of time.
As big mama says covid walks.

[marcusl2] 26/5/2023 22:29

JohnnyB1



RE: Covidity paper from Markus … covid up in ChinaToday 21:17
To be honest I skimmed through this paper as it is over my head. I was expecting it to be an in depth write up of the Covidity trial. Instead I was reading about experiments in mice and rats, I genuinely thought that I had lost the plot.

I eventually worked out that it is an updated version of the following paper on Scancell’s website dated 22 June 21:-



The extremely interesting thing about the updated document is that the affiliations now include the Disease Intervention & Prevention Program, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.

The Texas Biomedical Research Institute worked on the first Pfizer-BioNTech COVID-19 vaccine. I can recommend looking at their website and the short video in this link:-



Hopefully not a dead parrot after all : - )

[plasybryn] 26/5/2023 22:18

The three year chart perhaps suggest the share price has bottomed. With news imminent (surely) that would tie in.

[golcheja] 26/5/2023 20:48

Week before the ASCO, Share price will continue to slide if no update before. Puzzling and wonder how long it can remain floating above double digit. Driving on fumes and hope rather on concrete updates.

[golcheja] 26/5/2023 19:16

Again drumming the covid help line. As if scan had a proved vaccine in the cupboard.
I think folks are so squeezed they are loosing the plot. The big question does modi does what we all led to believe it will. To some extent we know it did, his significant it is a whether some big pharma is likely to put a pile of cash for it, remains to be seen. Meanwhile some offload today chucks of 25K each. I hope they flush after they git the cash. I for a change decided to invest another £500.
As big mama says spectacular RNS talks and covid vaccine BS walks.

[the real lozan] 26/5/2023 16:09

"Delighted to share" -
Someone seems to be 'trying TOO hard'
Some might be 'MORE DELIGHTED' if instead of repeated 'meaningless also available in several colours' sales trHYPE... WE ALL were given explanations as to why these shares are being traded at 14.5 P ???

Trying to CONvince the market
or
Trying to CONvince themselves
???

[marcusl2] 26/5/2023 14:48

Delighted to share our recent publication showing Scancell’s novel COVIDITY #vaccine elicits strong pro-inflammatory T-cell and neutralising antibody responses against variant #Covid19 strains.



Scancell
@scancellpharma
·
28m

[marcusl2] 26/5/2023 14:47

Scancell
@scancellpharma
·
28m
Delighted to share our recent publication showing Scancell’s novel COVIDITY #vaccine elicits strong pro-inflammatory T-cell and neutralising antibody responses against variant #Covid19 strains.

[panama7] 26/5/2023 13:20

Marcus, why bother with the MHRA and other regulatory bodies which are funded by the very organizations they are supposed to regulate. Let's just take their word for it and not bother to read the Clinical Trial papers. Oh hold on a minute we did that for the Covid vaccines, how has that worked out. As Billy Goats gotta get those needles in the arms of everyone on the planet to make us all safe. Good to see some MP's waking up to threat of the WHO pandemic treaty and changes to the IHR regulations.

[golcheja] 26/5/2023 11:24

AZ trial update today on Sky.
Is the biggest announcement of all is in waiting ?
4X
40X
Any X
As big mama says any X is a hero and the rest is zero.

[marcusl2] 26/5/2023 10:11

EE



“ In addition, from 2024, the MHRA will introduce a new approval process for the most "impactful" innovative medicines and devices, examples being cancer vaccines and artificial intelligence therapeutics for mental health. This is hoped to accelerate patient access to treatments and build on the success associated with the UK's rapid approval of Covid-19 vaccinations.”

[marcusl2] 25/5/2023 22:59

Results:
As of February 2023, the monotherapy dose-finding has completed. 3 patients received Mod1-1v (vimentin only) 80 µg/peptide and 3 patients received Modi-1 at 400 µg/peptide (vimentin + enolase peptides) as part of the monotherapy dose escalation. No DLTs were observed, triggering enrolment into the monotherapy expansion cohorts. 20 evaluable pts have received Modi-1v (3 pts Modi-1v 80 µg/peptide, 17 Modi-1 400 µg/peptide): 16 had HGSOC, 2 TNBC, 2 SCCHN with 53 doses received; 2 patients have been treated beyond 24 weeks. All patients had skin reactions consistent with a delayed-type hypersensitivity reaction at injection sites. Vaccinations have been well tolerated with 71 adverse reactions in 15 patients reported. All were Grade 1 or 2 except for four Grade 3 reactions in 3 patients (anemia, fatigue, and injection site reactions). There have been no SAEs. Elevation in anti-CCP antibodies has not been seen. In 13 response-evaluable patients, best overall response by RECIST v1.1 included 1 PR (SCCHN), 6 SD and 6 PD. The study is currently enrolling into the combination with checkpoint inhibition dose escalation cohorts and the monotherapy expansion cohorts.
Conclusions:

Modi-1 is well tolerated, and the early monotherapy efficacy data are encouraging. Safety and early efficacy data are supportive of further development of combination with CPI. Clinical trial information: NCT05329532.

[marcusl2] 25/5/2023 22:50

Bermudashorts


ASCO abstracts have been published today and below is link to Scancell's Modi1 abstract. Really good to see no evidence at all of raised levels of anti-CCP antibodies which are associated with RA and other autoimmune diseases. Looking forward to seeing extra detail on the poster when it appears on Scancell's website.



Results:
As of February 2023, the monotherapy dose-finding has completed. 3 patients received Mod1-1v (vimentin only) 80 µg/peptide and 3 patients received Modi-1 at 400 µg/peptide (vimentin + enolase peptides) as part of the monotherapy dose escalation. No DLTs were observed, triggering enrolment into the monotherapy expansion cohorts. 20 evaluable pts have received Modi-1v (3 pts Modi-1v 80 µg/peptide, 17 Modi-1 400 µg/peptide): 16 had HGSOC, 2 TNBC, 2 SCCHN with 53 doses received; 2 patients have been treated beyond 24 weeks. All patients had skin reactions consistent with a delayed-type hypersensitivity reaction at injection sites. Vaccinations have been well tolerated with 71 adverse reactions in 15 patients reported. All were Grade 1 or 2 except for four Grade 3 reactions in 3 patients (anemia, fatigue, and injection site reactions). There have been no SAEs. Elevation in anti-CCP antibodies has not been seen. In 13 response-evaluable patients, best overall response by RECIST v1.1 included 1 PR (SCCHN), 6 SD and 6 PD. The study is currently enrolling into the combination with checkpoint inhibition dose escalation cohorts and the monotherapy expansion cohorts.
Conclusions:

Modi-1 is well tolerated, and the early monotherapy efficacy data are encouraging. Safety and early efficacy data are supportive of further development of combination with CPI. Clinical trial information: NCT05329532.

[golcheja] 25/5/2023 21:09

Say goodbye to the conservatives for at least 10 years take cover as it will be painful.

[inanaco] 25/5/2023 20:48

one in the eye ............ for Rishi and others




Indeed, the only impact of those tax rises has been to deter investment, as we have seen from AstraZeneca and others both within the UK and overseas.

Once again, Truss’s view has been vindicated. The OBR and IMF were wrong, Truss was right.

Now the long bond has risen to the same level as it did during the mini-crisis. To the extent that an initial small jump in yields at the beginning of the process had anything at all to do with the mini-budget, it is now accepted by all that yields would not have shot up further without an entirely different cause: the rolling collateral calls, involving massive sales into the market of the long bond, from disgracefully over-leveraged, poorly regulated liability driven investments (LDIs) in pension funds.

And even as regards the initial small spook in the bond market, it commenced the day before the mini-budget with the astonishing announcement by the Bank of England that they were going to sell £80bn of gilts into the market as part of the new “quantitative tightening“.

For those who, with such assured certainty, blamed the rise in yields at that time on the mini budget, to what do they now ascribe the same high yields, six months on?

Do these commentators and actors now regret shutting down that one single attempt to reverse the long, now continuing, decline in the U.K.’s economy? I do.

telegraph

sadly what i posted at the time ........has proved correct ...

they have now modeled Starmers tax plan ... treasury £350m worse off ,,,

but they will have spent what was expected to be collected ! another huge black hole in the making

decline continues

Migrants in ....

Wealth out

[marcusl2] 25/5/2023 09:04

and while we are waiting for news, look what happened to this company after successful ADC phase I data appeared ;



it went from below 40 cents to over $13.5, which is a nearly 40x spike. Last year, the company was cutting workforce and finding it tough to gain compliance on NYSE. This year, it had this rally.

[inanaco] 25/5/2023 08:28

out of interest this is the system of statistics that apply to scancell modi 1 trial



short video

[golcheja] 23/5/2023 13:19

Triple zero,
Zero volume
Zero update
Zero interest
As big mama says, hero talks and zero walks.

[torquayfan] 22/5/2023 13:49

Ha ha ! And 57190 is a fine example for you to follow yourself Old Chap !

[the real lozan] 22/5/2023 13:27

57190 -
I totally agree
I would go as far as to say, that is one of Tarquin Eetup's better posts for many a year.