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OPTI Optibiotix Health Plc

15.25
0.00 (0.00%)
03 Jul 2024 - Closed
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Optibiotix Health Plc LSE:OPTI London Ordinary Share GB00BP0RTP38 ORD 2P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  0.00 0.00% 15.25 15.00 15.50 15.25 15.25 15.25 103,982 07:49:38
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
Noncomml Resh Organizations 457k 2.59M 0.0284 5.37 13.91M
Optibiotix Health Plc is listed in the Noncomml Resh Organizations sector of the London Stock Exchange with ticker OPTI. The last closing price for Optibiotix Health was 15.25p. Over the last year, Optibiotix Health shares have traded in a share price range of 7.35p to 43.50p.

Optibiotix Health currently has 91,190,661 shares in issue. The market capitalisation of Optibiotix Health is £13.91 million. Optibiotix Health has a price to earnings ratio (PE ratio) of 5.37.

Optibiotix Health Share Discussion Threads

Showing 30076 to 30100 of 147875 messages
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DateSubjectAuthorDiscuss
20/10/2017
21:55
Amazing how such great results can bring on slightly negative comments instead of celebrating the success. No wonder the brexit negotiations are swamped with doom mongers! I’m wishing Opti nothing but the best with their products!
moormoney
20/10/2017
21:52
I don't want to get involved with medical matters I know nothing about, especially as I don't suffer from high LDL, thus never taken medication for it. Chris makes a valid observation in the Adnan's cholesterol level increased by .5. However, what Chris seems to be missing the fact LP-LDL is in OTC supplement form produced by HLHBiopharma and I dare say there will be variables to OTC supplement manufactured to pharmaceutical specs in other territories and I would imagine have differing results, but within a range. Chris appears to comparing statin, as pharm medicine with LP-LDL an OTC supplement - You simply cannot compare them. OPTI have never made the claim LP-LDL can replace statins, but they have suggested it can be used in conjunction with. I take this to mean statin dose (in some cases) could be reduced if LP-LDL was being used. What is clear, the higher the LDL the better the results with LP-LDL.

Another point SOH made: "We also know from other studies that cholesterol can vary 5-10% throughout a day within an individual depending on the food they eat and the timing of testing and so a result based on a single subject can be subject to other factors which can mask an effect." We don't know what time Adnan's was tested, but we know he ate some lovely sweet treats the evening before, which I would imagine impacted on the negative side, so it is entirely possible the result could have been better than had he not buckled to his sweet tooth. ;)

elrico
20/10/2017
21:23
Adnan - SOH is asking me for your contact details. Please PM me so I can pass on your details to SOH. I can assure you I will NOT share with anyone else.

"As with Nick if you have his contact details it would be good to be able to get my PR company to speak with him as we are putting together an article covering the problem with pharma drugs in this area and our study data and it would be good to finish off with a few case studies of Nick and Dr Adnan."

elrico
20/10/2017
19:41
chrisg you posted

"Ferdinand..that is a very reasonable comment but makes the incorrect assumption that the cholesterol would quickly go up to previous levels which is not true..It would go up and is indeed going up even on LP LDL."

the above post of mine was to say that in my case it DID go back more or less to my previous lvs infact it could have been quicker than 3 months it's just that it was not tested until 3 months after stopping taking them.

How can you say ferdinands comment is incorrect and how can you say it is not true ?which in my case it was,what experience or knowledge have you in that field to make such comments

scotty1
20/10/2017
19:25
Scotty..next time I post scotty I will post outlandish interpretations of an increasing cholesterol and for you and risky when I report the conclusions of a scientific study I will deliberately miss out the word potential from the study conclusions and then everyone will no doubt be happy.
chrisg11
20/10/2017
19:14
chrisg i have been on statins for many a year after being able to control my cholesterol with diet only for years before taking statins since being on statins i have suffered bad muscle cramps.4 months ago i told my GP i wanted off statins again and wanted another go at controlling it by diet only.So thats what i did for 3 months a ridged diet i managed to loose 1.5 stone and felt sure my overall lvls would be down after a fasting test.Top and bottom is the lvls had gone back almost to pre statin days which i couldn,t understand as i really had no saturates and almost stuck to a fruit,fish,veggie diet,but as my GP said when you get into your 60s your body produces cholesterol no matter what you eat.The point i am making is that within 3 months of coming of statins my lvls had gone back up to within 0.3 of my pre statin days.I believe the idea is to use LPLDL in conjunction with satins ie if you are on 40mg drop it to 10mg (thus minimizing the side affects)and use LPLDL along side it.
Other than that m8 i see you have only posted 11 time all on OPTI and all with a negative tone.

scotty1
20/10/2017
19:07
'To keep it simple and understandable,this means that if LPLDL does indeed turn out to lower cholesterol this does not mean with certainty that it will lower cardiovascular risk significantly'See below.... we know LPLDL reduces cholesterol and Optis study also showed a decrease in blood pressure across the board which seems to have replicated with nick and Adnans recent findings.....The European Society of Cardiology Studies has reported the ability to reduce both cholesterol and blood pressure 'has a multiplicative effect in reducing cardiovascular risk' providing a significant advantage over single action products.
riskybusiness1
20/10/2017
18:59
The official results are exceptionally promising. Opti now have a string of evidence supporting LPLDL from lab studies, replica gut models and now human studies that have all replicated previous findings. Optis study of 50 reinforces previous evidence proving efficacy whilst also showing safety which is clearly key. 50 subjects is usually pretty similar to a pharma phase 2.There will need to be further trials e.g 100 - 200 people. A human study that includes the subjects taking a combination of LPLDL and LPGOS will be extremely interesting and if replicated earlier findings will take Opti to a whole new level of opportunity. The LPGOS fibre increases LPLDLs own efficacy x3 times in gut models whilst also having its own cholesterol reducing property. Optis LPLDL study was also on people with normal to mildly elevated cholesterol levels. The study by university of reading shows that the greater the starting cholesterol levels the greater the reduction. We know SOH has stated the next trials will be with subjects with higher starting cholesterol levels.Opti is very much at the front in terms of science in the birth of a revolutionary new market. I don't think any other company in this space has modulated the microbiome with such precision as has Opti using its patented reverse enzyme technology to extract a specific fibre from a specific organism (LPGOS recent deal with TATA). Very exciting space to be invested in.
riskybusiness1
20/10/2017
18:43
To make things clear..I am not trying to fall out with anyone on here but feel it is healthy to give another view and perspective on things.

A more complex spanner in the works which I now offer with a wry smile and wearing a tin hat is that the cardiovascular protection given by taking a statin is only poorly correlated to the cholesterol level.

To keep it simple and understandable,this means that if LPLDL does indeed turn out to lower cholesterol this does not mean with certainty that it will lower cardiovascular risk significantly but I would agree a bit of mischief with this particular comment.

chrisg11
20/10/2017
18:34
Johnhenry..

I am not sure of your expertise to say I am correct but you cannot make the conclusions you are doing from the results given.

You make an incorrect statement that the cholesterol would return to its 7.5 level within 3 months..It may do,it may not as it may take longer than 3 months.

chrisg11
20/10/2017
18:30
My cholesterol levels are in range 4.5, but my triglycerides are at 4 (max I believe is 2).Not started Statins. I recall this product also having good results on triglyceride levels.May give it a go.
vanduke
20/10/2017
18:28
Another thing to bear in mind as mentioned by Risky is this:- 'When we are talking about a potential Statin replacement when Opti combined LPLDL with LPGOS (the sugar that TATA has just signed to manufacture) there was a threefold increase in the cholesterol reduction compared to LPLDL on its own'. If Adnan had taken the combo, what would the results look like?

JH - we think LDL is keeping his score at 6 but it could move either way from here.

uzbek2
20/10/2017
18:19
Chrisg11 you are incorrect, when you come off statins your cholesterol level will return to its pre statin level.The fact that Ad levels have not returned to 7.5 shows that the LDL is in fact working to keeping his level at 6.
These facts come from my dads use of statins.

john henry
20/10/2017
18:17
Risky..indeed risky that may be correct but we cannot make those conclusions at this stage from Adnan's results although the claims may well turn out to be correct!

The BP results are quite interesting although a sample of 2 people both of whom are financial investors would not meet everyone's criteria.

I do agree that the microbiome is extremely interesting and promising hence my investment but getting carried away and making nonsensical claims will be detrimental in the long run.

Even the hype over the 50 people study is overdone but is interesting..

chrisg11
20/10/2017
18:04
Chris You are correct in terms of Adnans results not being of any scientific significance as with any individual private study. It is useful however to know that Adnan has remained at a healthy cholesterol level whilst coming off Statin medication for three months. It is likely that levels would have returned to levels prior to beginning a course of statins without taking LPLDL. This is clearly inconclusive but still useful to know. There are so many variables to consider, that is why Opti conduct double blinded placebo trials independently by experts in this field. It is definitely not a concern that levels have increased as we know from Optis studies those that have higher starting cholesterol levels have the greatest results..whereas Adnan started with very low levels following taking statins which is obviously a medication.The most significant information is that LPLDL is potentially better at reducing blood pressure than statins either way interesting to know peoples cases and should not be passed off as useless.
riskybusiness1
20/10/2017
18:02
Ferdinand..that is a very reasonable comment but makes the incorrect assumption that the cholesterol would quickly go up to previous levels which is not true..It would go up and is indeed going up even on LP LDL.
chrisg11
20/10/2017
17:58
yes Chris - I must be a lot brighter as I can see the other side of your argument - just posted
jimmylufc
20/10/2017
17:56
Kipper, ofcourse I agree with your comments but specifically - whilst statins decreased Adnan's cholesterol levels from 7.5 to 5.5 (and accompanying side effects, etc), now that he is on Opti's LP-LDL, his cholesterol has increased to 6.0, this has increased by 0.5 which is fact - what Chris (from memory) is not listening to is the counter argument which is that this is still a net 1.5 reduction from 7.5 (and hopefully more as he continues to use Opti's LP-LDL)

Anyway, its not like no research/trials have been done on this - all trial/tests have been very positive and as has been pointed out lower cholesterol levels together with lower blood pressure is a game changer which is why I have put my money where my mouth is and will continue to buy where I can

jimmylufc
20/10/2017
17:54
Uzbek2 has got it!
chrisg11
20/10/2017
17:52
Chris, surely the point about Statins is that they need to be continuously taken or your cholesterol levels will go back to the start point! You aren't cured of high cholesterol after taking a few statins! Therefore it makes sense that the initial high cholesterol reading is taken as the measure against OPTI's product! If it was no good then Adnan's level would have quickly gone back up to his pre-statin level!
f3rdinand
20/10/2017
17:51
You are obviously brighter than me jimmy.

So let's keep things simple and for the sake of discussion say that LPLDL reduced cholesterol which is brilliant news.

Can anyone tell me from what level it reduced it.

chrisg11
20/10/2017
17:50
The key in regards to results from LPLDL is to measure the reading 3 months and 6 month after using ONLY LDLPD with no other drugs being used prior to this. If Adnan had reported a fall from 7.5 to 6 without any use of statins, then can we say that LPLDL is a complete success. I am sure the probiotic does its job but we need to judge it in isolation.
uzbek2
20/10/2017
17:40
I agree with Chris to some extent. It is wrong to draw any conclusions from one unscientific test case, especially when the subject has a vested interest (as an OPTI shareholder). However, as SOH says, there have been controlled tests on 50 subjects under more scientific conditions. I haven't being listening in on the twitter discussion, but I hope it is focusing on those trials than Adnan's story (with all due respect to Adnan and thanks to him for his other valuable contributions to this BB).
kipper1960
20/10/2017
17:37
must just be you then Chris - can't see anyone else agreeing with you
jimmylufc
20/10/2017
17:28
I have read the responses and they are totally incorrect so I am pointing that out.

Read my last post which explains the results clearly and accurately.

chrisg11
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