1spatial Share Discussion Threads

[buzzzzzzzz] 20/4/2007 11:13

That 18% is now over 20% unless you bottled out and sold earlier?

[buzzzzzzzz] 20/4/2007 09:33

I cannot believe people are thinking of banking 18% when the prize is so much more!

EGM coming next week and I would expect to see buying before and after.

Why would anyone sell when SPA are in talks to sell 10% of the company to a major pharma, as the shareholder letter said they are talking to several.

The brokers note has a target of £1.50 and also indicates SPA will not stay independent.

Just to remind everyone again that Sirna was bought by Merck at a price that would value SPA at £6.

[rrb] 20/4/2007 09:26

Its a big 'IF'

[aglenn] 20/4/2007 09:22

sorely tempted to bank an 18% and buy back if dip occurs

[aglenn] 20/4/2007 09:21

Where are we going next week AB .?

[hoistman] 19/4/2007 21:35

They were going to be called "bloody clever chaps at SR Pharma plc" but it did'nt quite sound right so they came up with Silence Therpaeutics instead.
Well thats what I heard!

[rrb] 19/4/2007 13:02

because the technology is able to 'silence' diseased genes presumably

[old hand] 19/4/2007 01:06

Boof! Watch this go in a couple of weeks! EGM will be meaningless, what comes after! upppity! £1.50, at last Collins Stewart, they got something right, unbaleeeevabuuuble!!

[initiate] 18/4/2007 12:35

Yes, I guess you've got a point, I was just surprised to see such a sharp drop followed by a relatively rapid rise back up, recently my stock picks have usually had a sharp drop followed by a long drift downwards !

I see the name is going to be changed to Silence Therpaeutics - is there any particular reason why they have chosen this name ?

[alwaysbanking] 18/4/2007 12:26

Somehow I don't think so, the growth of one penny on the share price gets some folks bailing out - cant blame them - a profit isn't a profit until it is banked BUT just imagine where we would be if those big sales weren't going through. Im not knocking profit taking more of this will happen particularly on Friday - but I wouldn't like to try getting back in Monday cheaper than 88p.

[initiate] 18/4/2007 12:21

There seems to have been quite an intraday reversal here - MMS playing tricks this morning ?

[aglenn] 18/4/2007 10:51

Hopefully you may climb to new heights today...don't forget your oxygen mask

[alwaysbanking] 18/4/2007 10:44

Bit of De ja veu, I feel as though Ive passed that step before.

[alwaysbanking] 18/4/2007 10:08

Them bloody steps again.

[geoffmanana] 18/4/2007 09:14

A steep hill yesterday and rollercoaster today.....

[share_shark] 18/4/2007 02:12

yEHAAAAAAAAAA all.
Good luck everyone.

[geoffmanana] 18/4/2007 00:39

And capitalised at £97.2m mmmmmmmmmmmmmmmm that doesn't seem much...does it?

[alwaysbanking] 17/4/2007 22:59

Remember this article in the Mail in late January 2007, I wonder if any trial results are due.



British scientists are on the verge of producing a drug that could revolutionise cancer treatment.

It shuts down the rogue genes that cause cancer and is due to be tested on humans for the first time in the next few months.

If successful, the drug will be used to stop the disease spreading to other parts of the body, at the same time improving quality of life and life expectancy.

The technique, known as RNA interference therapy, is still in its early stages of development but one day it could be extended to treat other conditions ranging from asthma to Aids.

The drug works by preventing genes from making disease-causing proteins. Similar in structure to DNA, it should halt the disease in its tracks.

A London-based company, SR Pharma, was awarded a patent for a drug which specifically targets the genes involved in pancreatic cancer - one of the most deadly varieties of all.

Animal tests have shown the treatment both stops the tumour from growing and prevents it from spreading elsewhere in the body.

The first human trials are due to start in the next few months and it could be on the market within three years.

SR chairman Iain Ross said: "We are not attacking the tumour itself but attacking the spread. It is not a cure but it will prolong life and improve quality."

Pancreatic cancer accounts for three per cent of all cancers. It is most common in people in middle and old age.

About two thirds of cases are diagnosed in both men and women aged over 70 years. Often the cancer has a poor prognosis as it doesn't show symptoms until the disease is relatively advanced.

Using the same therapy to target other disease-causing genes could one day lead to new treatments for a host of other cancers and illnesses. "If it is proven to work in humans, interfering RNA will dramatically increase the possibility of producing drugs a lot more quickly," said Mr Ross.

Present naturally in the body, interfering RNA is thought to defend against invading viruses.

However, its importance remained unclear until nine years ago when U.S. scientists showed it had the ability to shut down specific genes.

The discovery of the effects of interfering RNA has proved so important that in October last year the U.S. researchers, Dr Andrew Fire and Dr Craig Mello, were awarded the Nobel Prize for Medicine.

Pharmaceutical and biotechnology companies around the world are now trying to produce drugs which harness the phenomenon.

At the forefront of the research, SR Pharma is the closest to testing a cancer treatment on humans.

Experts say the technique has potential - as long as researchers can administer the drug in a way that ensures it is not broken down by the body before it takes effect.

Hazel Nunn, of Cancer Research UK, said: "From laboratory studies it seems that RNA interference techniques could, in principle, hold the potential to treat a range of diseases.

"But we need to see significant advances in methods of delivering RNA into human cells before this technology could be used to treat diseases like pancreatic cancer."

[alwaysbanking] 17/4/2007 22:26

The new money for the 86p range today is very encouraging and all bodes well for an early morning tick up. All the indicators are showing very posititive (I know its getting repetitive but the 89p - 91p imho will be hit tomorrow and like HP said some days ago this share will be 1pound prior to the EGM. The EGM has been set for the specific purposes of getting some of the 10 if not all of the 10 onboard. If only one of them is a major pharma (HP)who comes onside the 1.50 broker target set some time ago may be adjusted significantly. This share is in breakout terroritory and I believe the Telegraph article has fuelled interest. This share has a mountain to climb and I don't want to come down yet. Short term,medium term and long term there is a lot of profit in it. To move on no news like it has following the results must mean that there is a considerable amount of confidence in it. Ian Ross has put his money where his mouth is with a near 75K pounds buy and he hasn't got out - so I'm not either. This will attract some press either tommorrow or at the weekend so hang on, take some rest and get ready for some more steeper steps tommorrow. 1.4m buys today with 937,000 sells - the spread has narrowed signicantly and the on balance volume is pointing upwards

[chicken charlie] 17/4/2007 22:07

I hope so.

[texicon] 17/4/2007 22:03

Could this be the start of a breakout?

[aughton 3] 17/4/2007 15:28

AB i have found your posts like most on here very imformative

[geoffmanana] 17/4/2007 14:29

Spot on again AB.

[digger27] 17/4/2007 14:28

Building up nicely. Wish I could afford 300k shares!!!

[levelhead] 17/4/2007 14:00

A quick calculation

on the 'bid' side (at all prices) you can sell about 300k shares.

On the 'offer' side just 90k.

That alone tells a story.