Silence Therapeutics Share Discussion Threads

[ukeagle2aus] 05/6/2014 12:18

Hey Bare good to hear from you, hope all is well in your world? The pool is still waiting for a SR Pharma reunion once we all strike gold! I'll do the click and find thing as you suggested and say hi to Saw for me and look after yourself. Eag x

[barefoot1] 04/6/2014 23:16

Hi Eagle...if you find an old post from him and click on his name you should find him. Last time you asked I found him and he was still posting on other threads....think hes maybe just moved on...:-) x

[buywell2] 03/6/2014 08:03

Richard the Lionheart Esq






.................... GOOD THINGS COMING FOR XENETIC .....................



Whilst Xenetic BioSciences was my 3rd choice in my Biotech stock picks , and I have referred to it as a 'Wild Card' choice before, albeit with the potential of being a 10 BAGGER PLUS from it's AIM Listing days.

I have now taken it OFF the 'Wild Card' List and placed it in my TOP Picks.

The BOD have done a GREAT Job of de-risking drug development and the USA move has added value already to existing shareholders with MUCH MORE set to come.





To anyone following my Source BioScience Group (SBS) or Cyprotex Group (CRX) threads which are BOTH Small Cap Pharma Biotech stocks , BOTH recently acquired USA companies or companies with existing USA operations and BOTH have attracted MAJOR INSTITUTIONAL BUYING over the last 12 to 18 months .

BOTH use the same NOMAD as Xenetic BioSciences

Cyprotex also operates in Watertown, Massachusetts which is 6 MILES AWAY FROM THE NEW XENETIC BIOSCIENCE LABS IN LEXINGTON , after acquiring Apredica USA


Cyprotex now also have a GLP LAB in Kalamazoo Michigan 386 miles away

after acquiring CeeTox USA



Source BioScience are looking to expand their footprint into other parts of the USA, already in California and Atlanta(two labs) .... I expect Massachusetts will be next as it is the BIGGEST PHARMA BIOTECH HUB in the whole of the USA.

Coincidence ?

Time will tell , but CRX and SBS BOTH offer testing and services to Pharma companies to get drug compounds through Pre-Clinical trials and identify any problems together with suggested solutions that sometimes occur with a new drug molecule , it is my hope to see the 3 Brit companies co-operate/collaborate via the NOMAD to help each other achieve BIGGER things.





.................... NOW COMES THE CUNNING PLANS .....................








ErepoXen® Phase 2 FDA compliant clinical trial results out of Australia/New Zealand by the end OF THIS MONTH.

My take is that

THIS RESULT IS GOING TO BE EXCELLENT AS XENETICS FUTURE IS RIDING UPON IT







THEY HAVE ALREADY SHOWN TO BE CIRCA 300% BETTER THAN EXISTING CHRONIC ANEMIA TREATMENTS IN A PREVIOUS NON FDA COMPLIANT PHASE 2 TRIAL

THIS IS NOT A NEW DRUG IT IS A REFORMULATED DRUG USING XENETIC TECHNOLOGY TO MAKE IT LONGER LASTING AND WITH BETTER EFFICACY






The Xenetic strategy for the rest of 2014 is either Plan A or Plan B







Plan A

Xenetic are in talks now with a NUMBER of BIG Pharmas regarding ErepoXen®

Their intention is to OUT-LICENCE ErepoXen® to one of these BIG Pharma companies, great phase 2 results will be KEY.

A licence will involve an upfront initial payment in my opinion of circa $50m plus % payments based upon sales and the BIG Pharma taking ErepoXen® through Phase 3 trials and approval at their expense.

Such an upfront licence fee will FUND the development of Xenetic ORPHAN drugs

XENETIC INTEND TO FUND AND DEVELOP THEIR ORPHAN DRUG PIPELINES THEMSELVES

Xenetic has enough cash to fund it's program for the next year


Xenetic plans to list on NASDAQ in either the 3rd Quarter or 4th Quarter of 2014



Again an upfront licence fee will PAY FOR THE NASDAQ LISTING





Plan B


If BIG Pharma plays games re ErepoXen® then the NASDAQ Listing goes ahead anyway but with a share issue based upon trial results coming out of Russia/India and the Dana Faber Institute


The most exiting of these which will attract USA investors BIGTIME is Xenetics AML candidate which has already been granted USA Orphan status




Xenetics ONCHOHIST candidate for acute myeloid leukemia(AML)

Initial results from Dana Faber show this new drug candidate HAS NEARLY DOUBLE the efficacy of the BEST CURRENT AML DRUG ON THE MARKET ( 55% V 30% )

But there's more


During other tests at the Dana Faber Institute the Onchohist candidate has also shown it could be effective against

1. A NUMBER OF OTHER CANCERS
2. A NUMBER OF OTHER LEUKEMIAS
3. A NUMBER OF OTHER LYMPHOMAS


The Dana Faber Institute scientist involved has said that OCHOHIST is the BEST thing he has seen in TWENTY YEARS

Re Leukemia Onchohist is the ONLY treatment that attacks the leukemia cells themselves and does NOT kill other healthy cells ie it is PURELY SELECTIVE in its target

VERY VERY EXCITING

And why Xenetic just might become another SHIRE

[pwilk47490] 31/5/2014 08:56

Hi All, Back into an upward trend now?

Anyway, new presentation on SLN's website:

hxxp://silence-therapeutics.com/2014/05/30/may-2014-investor-presentation-now-available/

[ukeagle2aus] 22/5/2014 22:19

Been away overseas for a few weeks. Anyone I know still looking in on this board? I fear for my old friend Geoff, it's not like home to disappear for so long? Any other old LT SPP comrades still around? Good to know if you are all Ok? Eag

[buywell2] 19/5/2014 08:34

Richard Griffiths also has a decent sized stake in Source BioScience Group (SBS)

80% of SBS shares are now owned by Instutional investors and the SBS Management

RNS out today tells why this has happened , turnover up 55% in 1st quarter

[bad robot] 09/5/2014 14:04

moved up 3.5% on one trade

[laylap] 07/5/2014 15:15

Placing sorted. I can see another run upwards now. ..... ahead of news within few months. Gla

[steffyloveshares] 01/5/2014 15:22

video interview
Silence Therapeutics morphing into commercial drug company

Ali Mortazavi, chief executive of Silence Therapeutics (LON:SLN) tells Proactive Investors that it is transforming into a product company as it tailors its development technologies into commercial drugs.

[ukeagle2aus] 16/4/2014 03:50

What a weird market at the moment, very easily spooked by anything and not sure the sell offs are justified with underlying global conditions continuing to be stable enough? Hopefully the mild panic eases off and some sense prevails soon. Eagle

[ukeagle2aus] 01/4/2014 09:18

Are we going to get an April Fools day spike? Only joking on its way to 250p so I was told somewhere anyway.

[ukeagle2aus] 31/3/2014 14:18

Tree shake, or earth quake, been here before.

LOL

Eag

[snoppity] 28/3/2014 02:39

But today's action suggests it's not heading for 250. Pushing up again?

[aquilla] 25/3/2014 11:09

My guess would be that a price has been fixed for the fund raising at around 250p. Supposed to be Chinese walls but these things have a way of getting out. :-)

[philjh] 25/3/2014 11:06

care to expand on that Stuart?

[stuart14] 25/3/2014 10:38

Leaky Leaky.

[rg710] 20/3/2014 18:35

As stated previously, smoke and mirrors. We've had a few years of incompetent and mistimed announcements BUT now with the stable of products at our disposal I'm hoping for a timely, private investor- beneficial proposal and outcome.

[waterloo01] 20/3/2014 07:16

LoL. Tree shake? More like all the fruit has just dropped off the tree in high winds! One potential positive...maybe they will announce some major progress alongside the fund raise, maybe not...

[ukeagle2aus] 20/3/2014 07:11

Tree shake!

[stuart14] 19/3/2014 17:22

Agree. Fishy for sure.

[rg710] 19/3/2014 17:14

Not a straight forward strategy for sure. Smoke and mirrors methinks.

[stuart14] 19/3/2014 16:56

I'm staying in. This announcement is fishy. Telling the market you are considering raising funds is a sure-fire 100% guaranteed way to generate stock selling and a lower share-price. Why do they need the shares though?