Synairgen Share Discussion Threads

[wetdream] 13/5/2020 19:23

I assume the late reporting is a function of the multiple of NMS
10k - no delay
20k - 1 hr
30k - 2 hrs
And son on.
So the 50k, 70k, 100ks qualify for next day(?)

Judging by today’s trades, there’ll be c.650K late reported tomorrow. Imho

[waterloo01] 13/5/2020 19:00

I did say finished recruiting, not finished trial. Not long to go.

[nobbygnome] 13/5/2020 18:57

There is no way the hospital study trial could have finished yet. All the patients will probably have been recruited by now but don't forget the patients are dosed for 2 weeks. The study won't finish until all patients have completed treatment so I guess towards the end of next week at the earliest will be last patient last visit as it's called!

[macmuck] 13/5/2020 18:51

Lansdowne are acting in consideration of their clients interests. Hopefully we can take advantage of that. As said all this means is that a shareholders can top up in the 50s: On what I think is a super product!

[macmuck] 13/5/2020 18:38

"Vitec far better to prescribe it before the need for ICU to help avoid the disease escalation."
And that's the reason I bought in Chinadog!
this share is ranging and I'm sure a lot of people are trading that!?
Anyway it's a good reason to buy some more shares tomorrow!
hopefully a nice comfortable base!?

[itshenderz] 13/5/2020 18:29

Market holding them back as 'delayed publication'. Don't agree with the lack of transparency myself but what can you do. Provides a good buying opportunity for those wanting a cheap entry so take the chance whilst its there.... if you trust the team of course ;-)DyorAll imvho.

[torreskid] 13/5/2020 18:26

southampton now recruiting patients to another study that has interferon as one of the arms...i am trying to get more details re-disease severity, and inhaled or iv method of administration

[cambradjones] 13/5/2020 18:22

Bad enough getting trades delayed until after hrs but why do we get so many from previous day's trading ?

[eeza] 13/5/2020 18:21

If the share price has gone down - they're sells.

Simples.

[best1467] 13/5/2020 18:21

I don’t believe the Hospital trail as finished as it would surely of been RNSd but I am surprised it can only be down to been extremely selective with Patient intake which hopefully will be rewarded.
From all the information I’ve researched and been posted here it does seem very likely for positive outcome the only slight negative is the trial size as seen numerous times the placebo effect in small number trials can be misleading

[itshenderz] 13/5/2020 18:13

All but one have been concluded as a 'buy' for those interested. Source 'London South East'

[paradise city] 13/5/2020 18:09

Yes my mistake I should of said buys or sells !

[itshenderz] 13/5/2020 18:08

I believe the '650k' was a total result, rather than a single trade.

[dealer55] 13/5/2020 18:01

Who cares. It’ll be a sell won’t it.

[paradise city] 13/5/2020 17:54

Buy or sell ?

[wetdream] 13/5/2020 17:49

650k delayed from yesterday.

[waterloo01] 13/5/2020 17:23

I'm really not bothered by Lansdowne, if they weren't selling, you wouldn't be able to buy in the 50s. They have their own strategy, which is clearly to bank profits pre results. They have done it numerous times and it's not an indication of the outcome, but if a trial fails, sure seems sensible post event!

[aquilla] 13/5/2020 17:18

Another interesting article:

Interferon emerges as potential treatment for COVID-19

"...A second study, published last week in The Lancet, tested another type of interferon, called beta-1b, in a trial with 127 patients in a Hong Kong hospital. In that case, only some patients received interferon as part of a triple-drug-combined therapy with two anti-virals, lopinavir and ritonavir. The study offered the therapy as soon as possible to those in early stages of infection – an approach that was possible in Hong Kong because everyone who tested positive for the virus there was admitted to hospital regardless of case severity.Even though we were just able to treat patients with mild or moderate disease, we believe we are able to prevent a lot of patients from developing complications in the second week, perhaps that would have required intensive care,” said Ivan Hung, a physician and professor at the University of Hong Kong who led the study....
The results showed that the patients who received the therapy that included interferon cleared the virus and were able to leave hospital, on average, four to five days sooner than those who received the other two drugs alone....
Dr. Fish said she is collaborating on another trial, planned in Australia, to evaluate whether interferon can prevent COVID-19 infection in uninfected individuals."

Now that would be an interesting development!


://www.theglobeandmail.com/canada/article-interferon-emerges-as-potential-treatment-for-covid-19/

[talk2dubya] 13/5/2020 17:16

There they are - those delayed trades. Has to be better way of doing this.

[waterloo01] 13/5/2020 16:51

That would be a huge result if it was repeated under double blind conditions.

[westmoreland lad] 13/5/2020 16:46

Nice one Aquilla

'' In a separate trial at Union hospital in Wuhan, China, COVID-19 patients who inhaled interferon in an aerosol formulation had faster improvement in respiratory symptoms and clearance of the virus from their blood than patients who did not receive interferon, according to another informal report by Chinese, Australian and Canadian researchers ''

[aquilla] 13/5/2020 15:47

Looks like interferon is being tried out in unexpected places:

[waterloo01] 13/5/2020 15:42

They must be fully recruited into the hospital trial by now. They only had a further 25 to go two weeks ago. Exciting times in any trial in getting to a read out, and they get a 2nd bite of the cherry with the 'home' trial.

I was reading around why Astra dropped out of the Asthma trial. Rather ironic really.

"However, an interim analysis found a “very low number of reported severe exacerbations,” according to AstraZeneca. As the primary endpoint looks at the proportion of subjects to suffer severe asthma exacerbations during their 14 days of treatment, AstraZeneca concluded the low rate of such events “could make primary endpoint conclusions difficult.” The Big Pharma has responded by stopping the study."

[nobbygnome] 13/5/2020 15:34

Yes pretty sure care homes are included.

[waterloo01] 13/5/2020 15:33

By definition anywhere that's not a hospital will almost certainly qualify.