Scancell Share Discussion Threads

[the real lozan] 08/4/2019 14:48

INCREDULOUS ...It HAS come to this -
The day = TODAY... When th M F F F sees inane'n'co 'brand' someone ELSE as - ILLITERATE ???
GUFFAW

[torquayfan] 08/4/2019 14:40

Terror - miaow !! But a good spot.
Tommy F is on a thought provoking trip it seems.
TF is in seventh heaven !



BTW - Terror is a cause of trouble too . . . .
And monikered much the same as a criminal offence !

ATB

[terror] 08/4/2019 13:18

TommyFlowers poking the Hornets nest.

The TF's seem to always cause trouble.

[torquayfan] 08/4/2019 11:17

Gazza - ah yes of course. A blue day - lovely . . .

[panama7] 08/4/2019 10:20

Scancell doing a Proactive presentation on the 25th, won't look very good if the IND isn't approved and that is the first question to come from the floor.

[gazza] 08/4/2019 10:13

TF,

You've been around long enough to understand BB speak:

"Shares still being dumped" = "I'd like the price lower so I can buy more"

[torquayfan] 08/4/2019 09:54

Terror - ''Shares still being dumped'' - not sure why you say that ?
Last time I looked the share price was up the merest ?

Lotsa transfers into 2019/20 ISA allowances going on too.

[the real lozan] 08/4/2019 09:25

inane'n'co v Credibility -What colour do *WE ALL* see ???
6 Apr '19 - 09:11 -
"Morning O N W et al -
Might one suggest / ask, Would *WE ALL* be 'surprised', if this saw 'A little blue' in the next week ???
I wouldn't."
.
YOU see, in order to be 'classed' as a RELIABLE poster, one needs to show the ability to be ABLE to get things RIGHT

[terror] 08/4/2019 08:36

Shares still being dumped and looks like some being transferred too.

[torquayfan] 08/4/2019 07:39

. . . and maybe, lessons in Japanese too . . .

[ivyspivey] 07/4/2019 12:09

Let us hope he has been having Mandarin Lessons

[bermudashorts] 07/4/2019 10:58

Think Biotrinity is primarily an investment conference so assume Cliff Holloway will be the one attending. Let's hope his diary is packed full with one to ones!

[bermudashorts] 07/4/2019 10:50

Ivy,

Yes, will be interesting to find out. Rather than personalised vax perhaps more likely is the session on Cancer vaccines & oncolytic viral therapies, day 2, stream 1, Discovery of Immuno-Oncology Therapies.

[ivyspivey] 07/4/2019 10:47

Another from Crumbs which SCLP are attending.

Pages 3 and 5 seem most relevant panel discussions

[ivyspivey] 07/4/2019 10:39

Thanks Boom,
Interesting to see what area of Oxford Meeting Londy covers.
Presume personalised Vax but see there are a couple of other sessions involving Vax and some big hitters there including Bion Tech

[bermudashorts] 07/4/2019 10:34

Ivy,

Yep Crumbs is an excellent poster and good to see publication of these abstracts. Should point out though that this isn't new research or new material. These abstracts were presented at the CRI-CIMT-EATI-AACR conference in New York back in September 2018.

There were about 5 or 6 abstracts involving Scancell and that's when we first found out about homocitrullination and Modi2. You may remember that there was a huge amount of discussion and speculation around these abstracts and a bit of a spike in the share price It was also the first time we had any detail around glycans.

As is standard practice, all abstracts from this conference are published at a later date in print in the form of an AACR supplement and that happened last month.

The posters for these abstracts which are related to the work directly carried out by Scancell are on their website. Link below.

Great to remind ourselves of what Scancell have though.

[ivyspivey] 07/4/2019 10:03

Morning TF.
Yes excellent posts by Crumbs.I know that you are one of the few who post on both boards and have had the odd criticism for posting stuff from the other board.
To me if it is an excellent find then it is definitely worth copying over.

[torquayfan] 07/4/2019 09:55

Hi Ivy - you beat me to it . . .

Van Geest's prostate vaccine research in the AACR Journal - wow !

[ivyspivey] 07/4/2019 09:35

And more.Big thanks to Crumbs.


Opinion: No Opinion
Price: 5.10
RememberToday 07:45The Prostrate cancer vaccine research done by Van Geest using ImmunoBody?
published Feb 2019


Shame scancell don't much publicise how much is going on and how broad our pipeline really is in it's multi product from 3 platforms abilities to target multiple cancer targets at different disease stages in combinations with other treatments or in indeed in mono setting..... hopefully these 2 new ImmunoBodies will attract further funding to get them into the clinic.

[ivyspivey] 07/4/2019 09:33

More from Crumbs

36Remember the headcase charity funded research for a vaccine well it produced fruit... published Feb 2019

' As a result of the highly promising preclinical results shown, the ImmunoBody® vaccination is currently being studied in a phase I/II clinical trial for melanoma. As a result the ImmunoBody® DNA vaccine has been selected as our method of vaccination. Syngeneic C57BL/6 mice and humanized C57BL/6 HHDII/DR1 mice were used to assess the TRP-2 and WT-1 directed ImmunoBody® vaccines. Mice were vaccinated biolistically with the ImmmunoBody® plasmid coated onto gold particles using a gene gun. An initial priming dose was given on day 0 followed by a boost on days 7 and 14. Mice were vaccinated with either a TRP-2-ImmunoBody®;, a WT-1-ImmunoBody® or a combination of the two. The immune response generated was determined by ex vivo IFN-? ELISpot using splenocytes derived from the spleen of immunized animals. Results from these dual vaccination experiments reveal that it is possible to use both of these vaccines in tandem without losing the specificity towards each vaccine-containing peptide. High level of peptide-specific IFN-?-releasing cells were detected directly ex vivo and the ability of these IFN-?-releasing cells to recognize targeT-cells that naturally express the WT-1 and TRP-2 antigens is being investigated. The efficacy of TRP-2-ImmunoBody®; with or without PD-1 at treating syngeneic orthotopic GL-261Luc2 tumors implanted in C57BL/6 mice is also currently being assessed. The combination of the two vaccines will also be assessed in the humanized HHDII/DR1 mice using a humanized B16 cell line that has had murine Beta-2m knocked out and HHDII and HLA-DR1 knocked in. Anti-PD-1 checkpoint blockade will also be incorporated into this vaccination regime with the aim of boosting the antitumor immune response.'

[ivyspivey] 07/4/2019 09:31

Original Crumbs link.Thanks to him for these .A very good poster.

56moditope presentations:
Katherine Cook 25th

Lindy Durrant 20th- 21st

[ivyspivey] 07/4/2019 09:29

Morning,

Couple of good links posted by Crumbs on other site which I thought worth copying across.

Here is slightly more detailed agenda from Oxford Meeting.

[ivyspivey] 06/4/2019 12:58

Yes trading action does suggest the MMs know they have a guaranteed supply of cheap shares and obviously one or two PIs will cash in wondering what is going on.Any distressed seller with no news and few willing to top up only leads to one thing and most will just wait and see.
Especially against a background of current Brexit uncertainty

[torquayfan] 06/4/2019 10:22

ONW FWIW ? - quite a lot, most helpful - thanks

[oldnotwise] 06/4/2019 09:31

Loz
Maybe.... :-)

Berm,
thanks for that, it's so similar to the first lot, and the timing's pretty realistic too, not to mention the trading pattern.
Well, we'll find out in the fullness of time.
Great weekend all!
AIMO
ATB