Hi Moljen at last your team is doing well much better than nine.
As you say the share price performance here has been shocking and those that highlight other disasters are simply trying to deflect from their own poor investment choice.
HAGW |
Gerald Ratners electric cars are not doing well also ... |
Considering that the Mango Mussolini's coin has lost 85% from its peak and his consort Melon Ears' coin has lost 95% then 'investors' clearly need saving from themselves. |
Give Starmer his due ... We may have escaped Tariffs, got a trade deal, with the left seething ... The beauty of Brexit
well if that does not restore confidence not sure what will
Oh .. Tax Cuts |
Sci the shadow stalker.....we know precisely where the company is at.
Most investors aren't interested in the detail anyways...
If everyone had a 'scientific grounding' the share price would still be where it is...
You don't understand markets.
Peeps sell simply because the stock is dropping...not because of exact trial numbers or timelines.
.
On a lighter note....I see a poster elsewhere intimated that you were a ham shanker ! |
Not to us it won't. That's the problem. |
This meeting will provide updates and information on current treatments, access and support and is primarily geared towards #patients, their families and carers. Supporting patient-centric meetings such as this allows us to better understand the patient perspective. We look forward to learning from and incorporating their guidance as we continue to translate our #innovation and creativity into increased and durable responses in patients without compromising safety, addressing hard-to-treat cancers such as advanced #melanoma. |
members of the Scancell team, will be on the ground in Birmingham, UK to attend the @Melanoma Focus Annual Melanoma Patient Conference, taking place 27-28 February. |
If not successful.....well.... |
Yep...a no brainer....
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If successful....there will be a much better time to buy...with less risk.
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Funding is about to dry up over the next 12 months.
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Definite 'no brainer' |
It only confirms my reasoning of why Buying scancell is a no brainer !! |
inanaco/marcus,
This latest funding round means Eikon will have raised an astonishing total of over $1.1 billion since 2019 and EIK1001 is their lead candidate! |
The probability of success of a cancer drug getting from phase 3 to commercial is around 24%.
.
Probability of success from phase 2... around 5%. |
 interesting that Modi2 is linked to Tr7/8
EIK1001 is a Toll-like receptor (TLR)7/8 agonist that stimulates myeloid and plasmacytoid dendritic cells, activating immune and inflammatory responses. This dual activity provides another pathway, distinct from effects on checkpoint proteins, to enhance antitumor T-cell activity alone or in combination with ICIs
Modi2
We and others have demonstrated in preclinical models the benefit of combining a peptide vaccine with a TLR ligand adjuvant to promote CD8 and CD4 T cell responses18,19,20,21. TLR ligands that stimulate strong Th1 immunity are often hydrophobic in nature and combined with hydrophobic nature of MHC binding peptides can lead to challenges for large scale manufacture and sterile filtration. The SNAPvax technology which enables formulation of hydrophobic MHC binding peptides with TLR 7/8 ligand that self assembles into nanoparticles has demonstrated superior immunogenicity and stimulation of CD8 T cell responses. Antigen delivered in this particulate form not only persisted longer at the dosing site but was also associated with uptake by APCs in draining lymph nodes21,22. In mouse models, no evidence of systemic localisation is noted unless delivered via an intravenous route2 |
well Marcus if they can raise for that i don't think scancell will have any problems
look at the grade 3 TRAE
Results: Fifty-one pts (median age 67 [range 33 to 86]) with multiple, distinct histological tumor types and with a median of 3 prior Rx regimens were enrolled. Overall, a total of 42/51 (82.4%) comb Rx pts experienced a treatment-related adverse event (TRAE). A total of 9/51 (17.7%) experienced a ≥ Grade 3 TRAE, including fatigue, cytokine release syndrome (CRS), hemiparesis, hypertension, joint range of motion reduced, muscular weakness, pancreatitis, rash (maculopapular), skin plaque, and stomatitis. Overall, 5/51 (9.8%) experienced manageable CRS, with only 1 discontinuation due to CRS. There were no deaths due to TRAEs. Of the efficacy-evaluable pts (n = 50), complete response (CR) or partial response (PR) was observed for 7/50 (14.0%), including 3 CR and 4 PR. Disease control (including CR, PR, or stable disease) was observed in 24/50 (48.0%). The median duration of response was 10 months (range = 4 to 32 months). Responses were observed in pts with prior anti-PD-1 exposure as well as in those with low or negative PD-L1 tumor expression. EIK1001 PK was linear and dose-proportional, and combination with pembrolizumab did not affect EIK1001 PK. Conclusions: Overall, EIK1001 was well-tolerated with a manageable safety profile and showed encouraging preliminary efficacy across several tumor types in combination with pembrolizumab. Responses were observed even in heavily pretreated patients not anticipated to respond to pembrolizumab monotherapy. Further development of EIK1001 is underway. Clinical trial information: NCT03486301. |
Looks like the emperor has finally twigged he is naked. |
Eikon Therapeutics raked in $350.7 million in a series D fundraising round announced Wednesday. That is money the biotech will put to good use as its lead candidate EIK1001 enters Phase III trials for advanced melanoma
EIK1001 elicited a 14% complete or partial response rate in patients with advanced solid tumors. Disease control rate was 48%. |
so you are posting from an Asylum ...
thanks for letting us know |
I've told you everything corrects inane ..not rocket science.
All traded assets move on the same patterns whether it's up .....or down.
Bitcoin is completing a small correction prior to flying much higher again.
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I'm not marketing anything...if peeps didn't buy the most lucrative asset humans have EVER known....that's up to them.
I hold seven figure sums in several cryptos inane....not just Bitcoin. |
what offence caused Bitcoin to enter a correction facility ?
or are you posting from an Asylum 2tyke
just wondered why you have stopped your marketing campaign ? considering you helds £millions |
Going North -
Just witnessed a 'skein of Cranes' noisily flying over heading north |
92m !
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Yes it seems pricey ...but it is correcting remember ... |
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