Sareum Share Discussion Threads

[wolfofwallstreets] 21/7/2024 16:04

Coming from the biggest mong of them all...

You still selling screenshots from here to your local uni...

Utter loon...

[horridhenry] 21/7/2024 10:09

Still mongs only then, bye bye

[wolfofwallstreets] 20/7/2024 23:35

Literally don't have a clue..

Ask your carer to type for you..

[criticalthinker1] 20/7/2024 20:45

Wolf I wonder if you are legal wolf as well..like senator etc.like maj who is pushing gdr...oh my the early rises so the mms take the naive..like prem...
Anyway it builds a nice case for lse disruption
I have all the screen shots.

[criticalthinker1] 20/7/2024 20:41

Are you invested?

Be careful with your response

[wolfofwallstreets] 20/7/2024 20:08

It's "you're"...

Quoting WIP...

Isn't he the loon who vanished when 737 wad handed back?!

Another loon...

You don't even know FOI rules...

1 billion...haha..

Pie in the sky..

Tim is going part time as he does nothing and they're out of cash...

[criticalthinker1] 20/7/2024 19:18

Your against the ropes wolfie ...September 2022

Wip
: News12 Sep 2022 14:05
Hi Celtic - as per my reply to Krone. I have to be vague sometimes. But hopefully you guys can read into my comments. 737 will get a new name. it cant not.

todays news re Tyk2 is additional confirmation. not going to bring us a revenue yet, we all know that. it could be the catalyst for a bidding war behind the scenes though. who knows. wont get an RNS until a formal offer comes in, might not be til this time next year. could be next week.

Every RNS that get's poo-poo'd on here as 'nothing to do with SAR, why bother' actually has everything to do with SAR. Its drug discovery coverage. free advertising. call it what you want. If FDA have just approved a Tyk2, and its a huge market, then why wont every other pharma be chasing that egg?

A 1Bn or 2Bn offer during P1/end of P1 is a much easier cheque to get signed off than a 6Bn+ cheque in 12/18 months time

I know it's happening! I've been in conversations without anything specific being said bit we hold the Holy grail of what is required.

Bleat all you want wolfie....lse can ignore my posts and somehow they become relevant when it suits them...but I know!

[wolfofwallstreets] 20/7/2024 19:11

Boring..

Zzzzzzzzzzzzzzzzzz

More copy and paste lol...

What does emma walmsley think...

[criticalthinker1] 20/7/2024 19:03

Yes I have Wolf. There is a reason. Its part of my persona. I NEVER give up when I know my voice can be heard/read and it is worthy of discussion.
Rather than instant dismissal without any worthwhile reasoning.
So I give to you this...again...

—
BY RUDYARD KIPLING
(‘Brother Square-Toes’—Rewards and Fairies)

If you can keep your head when all about you
Are losing theirs and blaming it on you,
If you can trust yourself when all men doubt you,
But make allowance for their doubting too;
If you can wait and not be tired by waiting,
Or being lied about, don’t deal in lies,
Or being hated, don’t give way to hating,
And yet don’t look too good, nor talk too wise:

If you can dream—and not make dreams your master;
If you can think—and not make thoughts your aim;
If you can meet with Triumph and Disaster
And treat those two impostors just the same;
If you can bear to hear the truth you’ve spoken
Twisted by knaves to make a trap for fools,
Or watch the things you gave your life to, broken,
And stoop and build ’em up with worn-out tools:

If you can make one heap of all your winnings
And risk it on one turn of pitch-and-toss,
And lose, and start again at your beginnings
And never breathe a word about your loss;
If you can force your heart and nerve and sinew
To serve your turn long after they are gone,
And so hold on when there is nothing in you
Except the Will which says to them: ‘Hold on!’

If you can talk with crowds and keep your virtue,
Or walk with Kings—nor lose the common touch,
If neither foes nor loving friends can hurt you,
If all men count with you, but none too much;
If you can fill the unforgiving minute
With sixty seconds’ worth of distance run,
Yours is the Earth and everything that’s in it,
And—which is more—you’;ll be a Man, my son!

[wolfofwallstreets] 20/7/2024 18:57

Criticalstinker..

You've been saying the same thing..

Over and over.

For years....

Give up...

[criticalthinker1] 20/7/2024 18:40

Wolf....

. These findings support urgent exploration in clinical trials of such aggressive HGSOC types, given an improved chance of combination tolerability with SRA737.

These reports are very careful not to ridicule themselves by misinformation...so as to be discredited....the extract above from my previous post hopefully makes it more digestible for you that this is pharma gold!
Hence I'm very well invested here.

[wolfofwallstreets] 20/7/2024 17:56

Criticalstinker..

Great post...

Didn't read it...

Guaranteed nobody else does either...

Too boring..too wordy...

Just do what you usually do...

Thank froth2 and sadoldtart for their wonderful contributions over the years...and talk about emma walmsley...

Nobody cares...

[criticalthinker1] 20/7/2024 17:49

Wolf a narcissistic individual/sociopath deflects by justifying their opinion by talking surreptitiously about something that is deflection, which is actual deflection from the actual topic that should be discussed. You fit within that profile. Hence I called you out and engaged to get your responses so that others could see it on here despite others advising differently.
I stand my ground!
Anyhow, good post on lse re SRA737.
I hope that they are paying attention to what I posted about SRA737 back along as a monotherapy.
Please see below from Science Direct 19.7.24. As I advised DO NOT dismiss SRA737 as a monotherapy as it gives an early start on multiple biomarkers....such as amongst the many...ovarian and endometrial....which then other holders of certain drugs (maybe patents coming to an end) think ...oh hang on let's try our drug with this SRA737 that as a monotherapy proves it can bind with other drugs to be more effective....hence their drug becomes 'reborn' .

In summary, we observed impressive single agent SRA737 activity in CCNE1amp PDX models, and the CHK1i/PARPi combination was synergistic in CCNE1amp cell lines, with a trend for a difference with the CHK1i/PARPi combination in vivo, with lack of statistical significance seen, with the same dosing regimen as that which was more successful in HRD models. Validated biomarkers for predicting response to CHK1 inhibition, for example, denoting high replication stress (i.e., CCNE1amp, MYCN), would be highly valuable and the use of SRA737, especially as monotherapy, should be considered early in the disease course. Hence, SRA737 is a potent, highly selective, orally bioavailable CHK1i that demonstrated activity in PARPi-sensitive, acquired PARPi-resistant BRCA1/2MUT and platinum-resistant CCNE1amp preclinical HGSOC cancer models. These findings support urgent exploration in clinical trials of such aggressive HGSOC types, given an improved chance of combination tolerability with SRA737.

When you join the dots as I've mentioned on here despite being ridiculed I made this information of where this drug was going way back...but that's why disruptors are employed...and even significant holders wish to ignore my postings. OK...
Not fussed.
I invested here for a reason, with others.
Let's keep this above the radar so we don't have a Sierra Oncology moment and we can putport that investors were aware of the potential by posts that last for perpetuity so any underhanded shenanigans will have to deal with the them.
All best Steadydanny
Nb. The science guys who developed SRA737 are getting fantastic results from 1801 which dovetails into 1802....
via translational studies.
Certain individuals moved on from SIERRA ONCOLOGY and still we are led to believe it was all about momontelieb....
Never ever in a month of Sundays does that hold water.

[wolfofwallstreets] 19/7/2024 16:31

"Once Peel hunt and RF are out of the way...and we get 1801 data back..we are due a rerate..."

Hahahaha..

Fools...

[wolfofwallstreets] 19/7/2024 15:57

Great post by Bobbler on LSE referencing me today....

I can't wait for sareum to die and the happy clappy rampers to get ruined...

"Our molecules" etc...

Let's share some links...

Let's worship sadoldtart/frothy2

Let's have a plaque made for Tim...

[wolfofwallstreets] 19/7/2024 09:06

Citizen69 over on lse with his boring "Friday forage"..

Let me copy and paste a bunch of irrelevant links..

Share price is falling you utter moron...

[wolfofwallstreets] 18/7/2024 16:29

Look at that share price collapse...

Where have all the happy clappy rampers gone again...

When's the takeover..

When's the yacht party ..

Hahahahahahahahahaha...

[wolfofwallstreets] 18/7/2024 08:18

Great post on lse about the crown prince clown, sadoldtart...

Stop copying and posting SOG and have an original thought of your own. you lead form the front as if you are some sage but you constantly have to re assess what you write. Remember you though an rns would have been delivered within a week of 30th June RNS. you cant help yourself

[wolfofwallstreets] 17/7/2024 23:44

Never in the history of investment has a BB had so many imaginary billion pound takeovers lol..

Utter bunch of clowns...

Probably getting ready with the next cash grab RNS..

[peaceandlove] 17/7/2024 21:22

What's so funny to me, is their ability to twist absolutely everything! Tim is stepping down and this is what's happening: 👇

"IMO do not think the Tim move to COO would have happened unless significant news is imminent. Question is if just 1801 related, 1801 and 2, a full T/O if not a takeover then hopefully 737 news will be out soon as we are now nearing 7 months from the related RNS. Exciting times watching for that next red dot or dots. GLA".

I might invest a few bob in Sareum tomorrow? It's way past time for another vague update from the Sareum board that gets enough people excited to cause a spike in SP?

Hmmm 🤔 maybe not 🤣😂

[wolfofwallstreets] 17/7/2024 15:18

Now some idiot poster is talking about £30 a share....

Hahaha..

What a loon...

Sadoldtart is such a moronic poster...

Don't know how he shows his face on that BB given the utter garbage he talks...

[wolfofwallstreets] 17/7/2024 14:26

Darkpooooooo

Didn't ask..don't care..

Takeover is fair taking its time hahaha..