Immupharma Share Discussion Threads

[the stinger] 12/8/2021 08:01

No support!

[the stinger] 12/8/2021 08:00

From starting a 2nd P3 in 2019 , here they are doing a P1 3 years later!!. Total Bull...

[on target] 12/8/2021 07:57

"we anticipate that the PK study will take between 8-12 weeks to complete"

[the stinger] 12/8/2021 07:53

1ultimate, you are deluded... we shall see however I suggest that the share price stays put or goes to 7p.... in the first instance that is.

[best1467] 12/8/2021 07:52

You can almost guarantee 12 months before start of Ph3 was that flagged expected

[nobbygnome] 12/8/2021 07:50

It will be very interesting to see how the market sees this announcement. For me clearly it's a vague negative because you have to guess that the phase III depends on the results from the PK study so is not yet guaranteed to go ahead. As I have said for years the half-life of Lupuzor will be extremely short. You have to remember that previously they couldn't measure it in blood and it's only because of an improvement in assays that they can now.

[1ultimate] 12/8/2021 07:46

Stinga you are really making yourself look like a real tit. I hope you have a few pairs of underwear because you’ll need them haha 😂 😂

[on target] 12/8/2021 07:42

PK studies take the form of a P1 study isn't that the case? Not sure there is anything different here other than semantics.

[the stinger] 12/8/2021 07:39

Told you all it was bull..... 5p today!

[qazwsxedc69] 12/8/2021 07:39

To spell the name of your own product incorrectly in the headline is quite spectacularly amateurish.

[nobbygnome] 12/8/2021 07:35

>> tom

You have to say yes to that question because why else would the FDA ask for it to be done before the phase III starts.

[nobbygnome] 12/8/2021 07:34

But yes with hindsight it does say ' to confirm the..... PK characterisations...prior to commencement of the trial'. So I missed that but I didn't hear anyone else mention a phase I study so I guess so did everybody else.

[tomboyb] 12/8/2021 07:34

Nobby? -

If what you say is correct then the PK has now become necessary - ?

Lets see what Mr Market says -

[tidy 2] 12/8/2021 07:32

Is it Kaboom news

[nobbygnome] 12/8/2021 07:31

>> On Target

'Develop an assay' not 'do a phase I PK study'. I assumed they would just use the assay they developed to monitor the PK in the phase III.

[1ultimate] 12/8/2021 07:29

Where’s stinga haha 🔥🔥

[bittorrent] 12/8/2021 07:29

Would you trust a company that can't even spell the name of their own product correctly?

[on target] 12/8/2021 07:28

Nobbygnome, this is from February - seems clear to me?"In response to the FDA input, Avion, in partnership with ImmuPharma, has plans to develop and validate a bioanalytical assay, to confirm the clinical pharmacology and pharmacokinetic ("PK") characterizations of Lupuzor(TM), prior to commencement of the Phase 3 trial."

[tomboyb] 12/8/2021 07:25

What does that mean? -

Are you saying the pharmacokinetic studies are there to assess the presence of Lupuzor(TM) in the body after administration of a single dose -

FDA does not believe? -

[david gruen] 12/8/2021 07:24

Note to self: Don't ask Nobby

[nobbygnome] 12/8/2021 07:23

I guess really the question is what will the FDA's reaction be when it becomes apparent from the study that the drug is no longer measurable after a number of hours.....

[david gruen] 12/8/2021 07:22

Great RNS, but would appreciate Nobby's view.

[nobbygnome] 12/8/2021 07:21

Yes not what I was expecting and presumably the start of the phase III depends on the results of this PK study. I assumed the FDA just wanted it monitored during the phase III and not to do a separate study. They must have some concerns....

Strange that the company didn't make this clear before.

[best1467] 12/8/2021 07:19

Well surprising RNS looks like the FDA doesn’t believe