Angle Share Discussion Threads

[5oletrader] 10/7/2024 19:35

HmmmHttps://www.illumina.com/company/news-center/press-releases/press-release-details.html?newsid=af5ab34c-75ca-4d05-9129-168a9e6fc928

[kryptonsnake] 10/7/2024 19:15

bones698

You can always return here in September to see if you can actually buy cheaper than now

Something tells me you'll be paying a lot more



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[united snakes of advfn] 10/7/2024 18:05

Pile this of kaka is not even worth 2p per shares.


This is heading DDDD's way.

Kaput.


Regards

US of A/

[bones698] 10/7/2024 16:27

Look like the press article caused a slight bump but there are still some placing shares to churn here and heading back to 14p unless some news comes. Personally I'm hoping/thinking it isn't quite ready yet and suspect sept for next decent news here. Hopefully I can time it right again.

Interesting to see what feedback comes from the agm too

[5oletrader] 10/7/2024 16:07

ILLUMINA - Liquid Biopsy CGP• Https://youtu.be/mMSeK6GdANU?feature=sharedReviewing some FACTS:• ANGLE is developing research assays using NGS. This includes a pan-cancer NGS panel that targets hundreds of loci across 61 genes using ILLUMINA's NextSeq 2000, which is NOW installed in ANGLE'sR&D laboratory.• This will allow ANGLE to BENEFIT from the EXISTING installed BASE of Next Generation Sequencing (NGS) instruments and for Parsortix-based assays to be EASILY INCORPORATED into EXISTING workflows and clinical practice.• The ROLE of liquid biopsy in IMPROVING healthcare - The targets of the Good Health and Wellbeing SDG goals are reflected in the UK's NHS Long-Term Plan which sets out ambitions for cancer care. One of which is:• GENOMIC TESTING WILL BE OFFERED TO 'ALL' CANCER PATIENTS -Ball parking a 'THESIS' - so bare with me + feel free to shoot it down or contribute?• ANGLE is collaborating with leaders in the molecular field to develop downstream molecular solutions. ANGLE plans to offer a molecular solution for 'RESEARCH' use in 2024.• There are approx 2.3MILLION women with 'BREAST' cancer globally.I'll take 3 countries:• USA - 274,375 • UK - 58,756• GERMANY- 74,016Total - 407,147 cases• 10% of this 'total'- equates to 40,714 patients.-Gets 'Interesting' when I consider this:• Sequencing an entire genome can COST as little as around $5,000 (taken from CRUK)HTTPS://www.cancerresearchuk.org/funding-for-researchers/how-we-deliver-research/our-research-partnerships/international-cancer-genome-consortium-'Hypothetical' research use only business case for AGL:• FACT - The use of CTC biomarkers in clinical trials is a RAPIDLY GROWING field enabling longitudinal monitoring of genomic, transcriptomic and proteomic changes. ANGLE believes that there is CONSIDERABLE POTENTIAL for further business with all its existing pharma customers as they have a pipeline of drugs in development where CTC ASSAYS could provide additional valuable information. NUMBERS 'hypothesis':• ?USA, UK & GERMANY dedicate 10% of patients to RESEARCH for NGS = 40,147 patients• Cost for sequencing is $5k. Being conservative ANGLE charge for example £2.5k per test• 40,147 patients multiplied (x) by £2.5k per test = £100M+• Time point monitoring three (3) tests per patient = 120,522 tests• 120,522 NGS tests multiplied (x) by £2.5k per test = £300M+-Icing on cake?• We know there are 23,000 Illumina sequencing instruments installed globally across 155 countries.• What if 10% of ILLUMINA's sequencers require a PARSORTIX instrument to pair alongside = 2,300 parsortix instruments? • 2,300 x £10k each (guess) = £23M additional revenue-CONCLUSION:Illumina were happy to PROMOTE Angle recently:• "Targeted sequencing of Circulating Tumor Cells captured by Parsortix® System enables low frequency variant analysis with NuProbe VarMapTM Pan-Cancer NGS Panel" Https://emea.illumina.com/content/dam/illumina-marketing/emea/PDF_Files/Illumina%20EACR%2010-13%20June%202024%20Activity%20Promotion%20A4.pdf'Not' unreasonable to conclude a relationship is forming here?-Some additional NHS (for info only)• Whole Genome Sequencing for suspected cancerHttps://www.england.nhs.uk/wp-content/uploads/2021/07/genome-sequencing-cancer-patient-information.pdf• World-first genomic testing scheme ensures every child gets the best cancer treatment for themHttps://www.gosh.nhs.uk/news/world-first-genomic-testing-scheme-ensures-every-child-gets-the-best-cancer-treatment-for-them/• Whole Genome Sequencing - project Https://centralsouthgenomics.nhs.uk/transformation-projects-patients/whole-genome-sequencing-for-cancer/-"Thinking Aloud" (Possible in the short term?) ATB

[waterloo01] 10/7/2024 14:17

Since when to NOMADS talk to punters about the prospects and pricing for one of their companies? Pure fantasy.....

[atmysignal] 10/7/2024 14:10

Yes, but at the same period, it dropped to 42p

[countbasie1] 10/7/2024 13:49

Avct has released a lot of good news in the past two months.

[atmysignal] 10/7/2024 13:47

Why did avct do a 50p placing an now at 82p?

[atmysignal] 10/7/2024 10:41

Spoke to the Nomad this morningHe said he wouldn't rule out 80s after the update is revealedDyor

[amelio] 10/7/2024 09:18

Bang on Kryto, this does an AVCT, everyone is seeing it so it will. Easy 40-50% from here. imo.

[sawney] 10/7/2024 07:52

Goosed...
Thanks...I was thinking more along the lines of 50p but...I don't think other Pharma's would let it go cheaply...
Meanwhile...seems a lot of churn to get through since the placing... before this moves appreciably higher... without news..

[kryptonsnake] 09/7/2024 19:52

Avacta recently did a 50p placing and now it's 50% up

It won't be long before Angle is back in the low 20's



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[gooosed] 09/7/2024 17:45

sawney - I would venture that at this stage of development, with the potential of capitalising on the three Pharma deals signed - anything under 80p qualified as low ball.

Were the number of Pharma deals to grow & include all six of the "household names" albeit in early pilot studies, add in the Solaris Healthcare patient base, a successful outcome to the Bioview collaboration & lets not forget the Ovarian update - then a conservative estimate would (imho) be a considerably larger figure.

[kryptonsnake] 09/7/2024 17:00

To keep things in perspective the share price is still over 75% up since the 52 week low in November

If the trolls put as much effort into buying shares as they do trolling, they might actually make some money

I hope their master has closed their shorts



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[barnes4] 09/7/2024 15:52

Clearly a phat leak at angle right

I mean right Angle ??

[bagpuss67] 09/7/2024 15:39

I was going to say 25p too for a low ball offer!

[iomdm] 09/7/2024 15:35

millwallfan, totally agree.

[millwallfan] 09/7/2024 15:28

Given the known potential most holders would probably think £1 as lowball - but 25p is probably more realistic !! The abject failure to commercialise this shortly after FDA is disgraceful- there should have been numerous contracts in place based on FDA approval, - not get it then start thinking about how to get market interest. This is life changing technology for worldwide cancer sufferers and it is beyond incredulous multiple pharmas and the healthcare industry both public and private sector have not adopted it with open arms.

[countbasie1] 09/7/2024 15:22

Here we go.

[sawney] 09/7/2024 12:33

I'll bite...:-)...what would you regard as a low ball offer...?

[gooosed] 09/7/2024 11:43

There's clearly a concerted effort on the PR front . . . . a low ball offer just prior to the AGM might be fanciful but stranger things have happened.

[bsg] 09/7/2024 10:43

Only if they start selling their stuff.