Share Name Share Symbol Market Type Share ISIN Share Description
Angle Plc LSE:AGL London Ordinary Share GB0034330679 ORD 10P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -0.50p -1.09% 45.50p 45.00p 46.00p 46.00p 45.50p 46.00p 89,900 09:00:14
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Support Services 0.6 -8.9 -10.1 - 64.83

Angle Share Discussion Threads

Showing 47751 to 47774 of 47775 messages
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DateSubjectAuthorDiscuss
18/9/2018
22:16
I see my prediction coming true as always . The share price will continue to slide as agl burn through the cash and fail to deliver any meaningful news or sales . Unfortunately this has been the pattern for far too long and even with supposed partners selling the product nothing ever seems to come of it . Meanwhile the sosts are increasing and cash running low very soon before the inevitable cash call to shareholders yet again just to pay management's bloated wages at mug punters expense . It really is time some of you on here woke up and smelt the coffee instead of living in cuckoo land . How many years has it been like this 6-8 years . Hell even the FDA approval is going on for 3 years now and still no sign of it cóming again as I predicted . Unfortunately some folks will only learn when it costs them all their money but you can't say you weren't warned
bones698
18/9/2018
21:27
Agree. However we don't know the reason for the fall and whether it will turn out to be positive. Disappointing if long term shareholders sell some as a result of this downward movement and a good rise follows. Only back in July finnCap had a 110p target.
4legs
18/9/2018
21:17
An exCeptionally disappointing share price performance by any yardstick.
escapetohome
18/9/2018
21:15
Two 20,000 trades and one 10,000 trade, marked as sells on advfn, showing as buys on a couple of other sites.
4legs
17/9/2018
07:55
Auphilman - not being myopic, the NHS is not the most influential organisation in the world. It’s an easy target, but needs reform. Listening to that BBC programme, it would suggest that there is an opportunity for the private sector to make the running: if you could get an immediate test for a few hundred quid, self-funded, you probably would. I wouldn’t have invested here if I didn’t have full confidence in Parsortix.
semper vigilans
16/9/2018
21:41
It seems like the USA is the major target anyway.
jelenko
16/9/2018
20:22
Agree MW, better and faster diagnoses perhaps, but then will the NHS be able to cope with actually treating people? I doubt it as rationing is the way of doing things.
semper vigilans
16/9/2018
20:01
listened on iplayer; seems the wonderful RCPath has got the numbers required wrong again- though granted it's always difficult to estimate years ahead how many will be needed and to take into account imports and exports to the middle east, india, europe and republic of ireland; don't expect parsortix to make any difference in the short term; initiatives that might make a difference- digital pathology, fewer mdt meetings to attend to, having skilled technical staff interpret some of the simpler cases, cysts and keratoses etc, changing the pension rules that might encourage staff to work on rather than having to retire because their pension pot is full, greater promotion of pathology as a worthwhile career in medical school and to junior medical staff, tighter restrictions on employing agency staff, mostly overseas graduates who enjoy pay rates of £100-130 per hour, less form filling eqa, bureaucracy, health and safety, fire lectures, revalidation. In short, the system is as presently set up destined to fail, being a centrally directed soviet style massive nhs with no flexibility.
mw8156
16/9/2018
12:00
Has anyone else just listened to Adrian Goldberg on 5 Live investigating pathology services are. cancer biopsy analysis and the NHS system being in a mess in many places. There is a shortage of qualified scientists and the usual NHS inefficiencies. Parsortix would surely help the situation.
semper vigilans
15/9/2018
09:10
Good to see we are partnering with the leading player hTtp://prsync.com/marketsandmarkets/qiagen-nv-and-roche-diagnostics-are-the-the-leading-player-in-the-liquid-biopsy-market--2660276
waterloo01
14/9/2018
10:04
I’m on your level too Out! Thanks for the tech. info Clause. I see Angle are hiring: hopefully new posts rather than replacements.
semper vigilans
14/9/2018
09:55
If HIV, and other 'blood borne' diseases can pass to the recipient through contaminated blood, and by-pass the immune systems of that recipient, why couldn't cancer through CTCs ? ( In these things I'm ignorant, so asking what might be a stupid question )
outsizeclothes.com
14/9/2018
09:31
There is a significant delay between harvesting and transplanting organs. During that time the tumour cells were static in the blood vessels, perhaps the tumour cells bound to the vessel walls or passed between the endothelial cells to leave the vessel. In that case the tumour in the recipient would originate from the donated organ, and other tumours in the recipient would be secondary from that. The main point is that the patients were then immunosuppressed, so the CTCs could grow unhindered. CTCs in donated blood should be mopped up by the recipients' immune system. However, there must be a very small possibility of an immunosuppressed recipient of donated blood getting cancer. Previous studies have not found transmission of cancer in blood transfusion, but there is no doubt free cells can pass cancer, it is well known that cells left on surgical instruments can transmit cancer, and instruments that are difficult to clean are now often disposable.
clausentum
14/9/2018
06:54
That is a scary thought outsize, though it shouldn't be too much of a problem, simple blood test using Parsortix would suffice
willfy
13/9/2018
23:46
Having now read the extract from the American Journal of Transplantation hTTps://onlinelibrary.wiley.com/doi/abs/10.1111/ajt.14766 I can't help pondering another question:- If a donor organ recipient can develop cancer from an organ of a person with undiagnosed cancer, what about the recipient of a blood donation from a similar undiagnosed donor who is shedding CTCs ?
outsizeclothes.com
13/9/2018
19:38
Very true. That’s why I’m keen to know from the AGM the sales expectations once FDA approves. Last year the CFO talked about being close to the inversion point of a hockey stick style growth for sales. Realistically hardly any growth this year worth talking about so what’s the plans to make it happen? And how quickly?
ih_575893
13/9/2018
18:50
My daughter has been for a 100000 genome test today which requires a blood sample.I spoke to the nurse who fronted the programme and she had never heard of Parsortix, kinda not on the NHS radar yet. But can't help think why they waste so much money and effort doing these basic researches when the technology is out there.
smoothride
13/9/2018
14:05
American Journal of Transplantation This link may get you to it: hxxps://onlinelibrary.wiley.com/doi/abs/10.1111/ajt.14766
clausentum
13/9/2018
13:29
hTTps://www.independent.co.uk/news/health/organ-transplant-breast-cancer-donor-sepsis-a8535861.html. Several newspapers have it, but I can't find a link to the original report
outsizeclothes.com
13/9/2018
13:20
Clausentum - any chance of a link to the report, please ?
outsizeclothes.com
13/9/2018
07:39
Thanks Clausentum - especially pertinent regarding contaminated blood transfusions in the past.
semper vigilans
12/9/2018
21:46
Clausentum, it is indeed a very interesting read. Thanks for sharing. As you say another possible use for Parsortix.
maxie23
12/9/2018
21:37
Interesting. Was listening to R4 programme today about AI in medicine. Says huge numbers of women carry a cancer but that in vast majority their immune system counteracts it. Presumably the recipients immune system here was not able to do so.
ayl30
12/9/2018
20:15
I have just read an interesting report. A woman died from a stroke, 5 of her organs were donated, and 4 of the recipients developed breast cancer. They did not detect that the woman had breast cancer at the time of the donation. So she must have had Ca breast viable CTCs in the blood in the donated organs, and that combined with the immunosuppressive drugs post-transplantation enabled the tumour to spread and grow in the recipients. So we now have another use for Parsortix, checking potential donors for previously undiagnosed cancers.
clausentum
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