Abraxis Bioscience (MM) (NASDAQ:ABBI)
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From Mar 2020 to Mar 2025

Abraxis BioScience, Inc. (NASDAQ:ABBI), an integrated, global
biopharmaceutical company, today announced an agreement with the
University of Southern California (USC) that provides Abraxis with the
exclusive worldwide development and commercialization rights for an
intellectual property portfolio of diagnostic protein biomarkers for
therapy response, therapy toxicity and disease recurrence in colorectal
cancers (CRCs). Financial terms were not disclosed.
The intellectual property licensed is based on USC research by Associate
Professor of Medicine Heinz-Joseph Lenz and colleagues. USC Stevens
Institute for Innovation facilitated the licensing transaction. While
surgery currently is the treatment of choice in earlier stages of
colorectal disease, the research team, led by Dr. Lenz of the Norris
Cancer Center in the USC Keck School of Medicine, discovered a broad
range of molecular biomarkers and diagnostic tools that may better
predict therapy response rate, the overall outcome and survival rate for
patients with CRC.
The goal of this continued research is to combine prognostic markers
with specific therapeutic agents, which would enable clinicians to
tailor therapy to the molecular profile of the patient while minimizing
life-threatening toxicities.
�The era of predictive, personalized
evidence-based medicine has arrived. This type of research is only the
beginning as we embark upon the future of personalized medicine and
empower physicians to provide customized therapy for each patient they
treat,� said Patrick Soon-Shiong, M.D.,
chairman and chief executive officer of Abraxis BioScience. �We
look forward to continuing the work of Dr. Lenz and value the commitment
of USC to bring these discoveries to widespread clinical application
both as therapeutic tools and diagnostic discovery.�
In recent years, research studies on a global scale have attempted to
define subsets of biochemical markers that may be useful predictors of
response to treatment (evaluated through clinical response, toxicity and
time to disease progression) and prognostic markers which are equally as
important in determining the aggressiveness of CRC as well as other
diseases.
�Many CRC patients succumb to their disease
and a significant proportion will experience severe treatment-associated
toxicities while deriving little or no benefit. The licensing agreement
with Abraxis, and the furthering of this research, could help to
overcome this significant concern and enable physicians to select the
most effective and least toxic therapy for patients with colorectal
cancer,� said Professor Lenz.
�USC is committed to innovation -- the process
of translating new ideas into tangible societal impact,�
said Krisztina Holly, USC Vice Provost and Executive Director for the
USC Stevens Institute for Innovation. �The
relationship with Abraxis Bioscience is a perfect example of how the
right partnership can transfer research from lab to market, with the
goal of making a difference in people�s lives.�
Added Toni Gray, Senior Licensing Associate for USC Stevens, �By
licensing these important innovations in CRC prognostics, Abraxis has
demonstrated an innovative approach as well as a commitment to meeting
the needs of critically ill patients, now and in the future.�
Colorectal cancer is the third most commonly diagnosed cancer in both
men and women in the United States with a predicted 149,000 new cases
this year and remains the second leading cause of cancer-related deaths
in the Western world with an estimated 55,000 deaths in the United
States in 2006.
About Abraxis BioScience, Inc.
Abraxis BioScience, Inc. is an integrated global biopharmaceutical
company dedicated to meeting the needs of critically ill patients. The
company develops, manufactures and markets one of the broadest
portfolios of injectable products and leverages revolutionary technology
such as its nab� platform to discover
and deliver breakthrough therapeutics that transform the treatment of
cancer and other life-threatening diseases. The first FDA approved
product to use this nab platform, ABRAXANE�,
was launched in 2005 for the treatment of metastatic breast cancer.
Abraxis trades on the Nasdaq Global Market under the symbol ABBI. For
more information about the company and its products, please visit www.abraxisbio.com.
About the USC Stevens Institute for Innovation
The USC Stevens Institute for Innovation (http://stevens.usc.edu)
is a university-wide resource in the Office of the Provost at the
University of Southern California designed to harness and advance the
creative thinking and breakthrough research at USC for societal impact.
USC Stevens identifies, nurtures, protects, and transfers the most
exciting innovations from USC to the market, and in turn, provides a
central connection for industry seeking cutting-edge innovations in
which to invest. Furthermore, USC Stevens develops the innovator as well
as innovations, through educational programs, community-building events,
and showcase opportunities. From the biosciences and technology to music
and cinematic arts, USC Stevens connects faculty, students, and the
business community to create an environment for stimulating and
inspiring the process of innovation across all disciplines.
FORWARD-LOOKING STATEMENT
The statements contained in this press release that are not purely
historical are forward-looking statements within the meaning of Section
21E of the Securities Exchange Act of 1934, as amended. Forward-looking
statements in this press release include statements regarding our
expectations, beliefs, hopes, goals, intentions, initiatives or
strategies, including statements regarding the development of the
licensed intellectual property portfolio. Because these forward-looking
statements involve risks and uncertainties, there are important factors
that could cause actual results to differ materially from those in the
forward-looking statements. The development of the licensed intellectual
property portfolio could be affected by a number of factors, including
unexpected safety, efficacy or manufacturing issues, additional time
requirements for data analyses and decision making, the impact of
pharmaceutical industry regulation, the impact of competitive products
and pricing and the impact of patents and other proprietary rights held
by competitors and other third parties. Additional relevant information
concerning risks can be found in Abraxis BioScience's Form 10-K for the
year ended December 31, 2006 and other documents it has filed with the
Securities and Exchange Commission.
The information contained in this press release is as of the date of
this release. Abraxis assumes no obligations to update any
forward-looking statements contained in this press release as the result
of new information or future events or developments.