Holding(s) in Company

RNS Number:9296E
Alexon Group PLC
5 November 2004




                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ALEXON GROUP PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     CAPITAL GROUP

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18



4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

      SEE BELOW

5)   Number of shares/amount of stock acquired.



6)   Percentage of issued Class


7)   Number of shares/amount of stock disposed


8)   Percentage of issued Class


9)   Class of security

     ORD 10P SHARES

10)  Date of transaction



11)  Date company informed

      5/11/04

12)  Total holding following this notification

       3,861,788
               
13)  Total percentage holding of issued class following this notification

       6.466%

14)  Any additional information



15)  Name of contact and telephone number for queries

      R. PIGGOTT
      01582 723131

16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification ....5 NOV 2004....................


Letter to Alexon Group plc

Date: 3 November 2004


                         SECTION 198 NOTIFICATION 
                         Notification of Decrease


This Notice is given by The Capital Group Companies, Inc. on behalf of its
affiliates, including Capital International S.A., Capital International Limited,
Capital international, Inc., and Capital Guardian Trust Company, pursuant to
Section 198 of the Companies Act 1985.

The interest in the relevant share capital indicated below arises by virtue of
holdings attributed to the Companies (see Schedule A). These holdings form part
of funds managed on behalf of investment clients by the Companies.

         Share capital to which this relates;


            Ordinary Shares (59,723,467 shares outstanding) 

         Number of shares in which the Companies have an interest:

            3,861,788 

         Name(s) of registered holders(s):


                See Schedule B

As of 3 November 2004

Alexon Group plc

                                                       Number of      Percent of
                                                         Shares     Outstanding

The Capital Group Companies. Inc. ("CG") holdings       3,861,788       6.466% 

Holdings by CG Management Companies and Funds:


* Capital Guardian Trust Company                        2,795,926     4.681%

* Capital International Limited                           969,874     1.624%

* Capital International S.A.                               21,791     0.036%

* Capital International, Inc.                              74,197     0.124%


                                       Schedule A


                       Schedule of holdings in Alexon Group plc
                              As of 3 November 2004
 
                           Capital Guardian Trust Company

Registered Name                                               Local Shares

State Street Nominees Limited                                    117,537
Chase Nominees Limited                                         2,458,926
Midland Bank plc                                                 219,463

                                                TOTAL          2,795,926


                                    Schedule B



                          Capital International Limited

Registered Name                                               Local Shares

Chase Nominees Limited                                          969,874

                                                TOTAL           969,874


                                    Schedule B



                             Capital International S.A.

Registered Name                                               Local Shares

Citibank London                                                 21,791

                                                 TOTAL          21,791


                                    Schedule B


                              Capital International. Inc.


Registered Name                                               Local Shares

State Street Nominees Limited                                   29,809

Chase Nominees Limited                                          44,388

                                                       TOTAL    74,197

                                   Schedule B


                                 
                      This information is provided by RNS
            The company news service from the London Stock Exchange


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