Verona Pharma Share Discussion Threads

[digger18] 19/8/2022 11:45

Yep, especially with the number COPD sufferers in China.

[mo78000] 19/8/2022 07:21

This is hugehttps://www.globenewswire.com/news-release/2022/08/19/2501348/0/en/Nuance-Pharma-receives-Clearance-to-begin-Pivotal-Clinical-Trials-with-Ensifentrine-for-COPD-in-China.html

[digger18] 15/8/2022 20:51

Massive $150m raise, fully subscribed at $10.5 per ADS. Fully backed and funded!

[mo78000] 14/8/2022 21:47

If VRPs past history is anything to go by this will tank in the next week! Hope I'm wrong. LTH

[haroldthegreat] 14/8/2022 20:33

broker target of $25 when ?

[mo78000] 14/8/2022 18:41

https://pharmaphorum.com/news/verona-cues-up-filings-for-copd-drug-after-it-aces-phase-3-test/

[mo78000] 12/8/2022 20:31

Another positive day....just 50% more and il be even....been in this since 2007.

[digger18] 11/8/2022 20:38

This demonstrates high confidence in Enhance 1 and will fund initial marketing.
Broker target is circa $25, but in market, who knows!

[tradertrev] 11/8/2022 14:54

I expect most have seen this, but here it is anyway...

Issue size up from 10m to 12.4m ADRs at $10.50 raising $130m before fees. Greenshoe option of additional 1.84m ADRs, which given a current price of $12 is probably going to be exercised.
This could be the last Verona share issue!!! (Probably not though :-) )

[haroldthegreat] 10/8/2022 22:01

I have the answer from Wikipedia . It was Glaxo !

RPL554 was part of a family of compounds invented by Sir David Jack, former head of R&D for GlaxoSmithKline, and Alexander Oxford, a medicinal chemist; the patents on their work were assigned to Vernalis plc.[4][5][6]: ;19–

Time for Glaxo to get it back and make a bid ,now we have shown them it works .

[haroldthegreat] 10/8/2022 21:53

Well perhaps we might see our money back if there is a takeover , I believe this came from Glaxo when they lost interest in it but I may be wrong . Perhaps they will want it back ?
Actually i want more than my money back i am after an index linked return from date of purchase .
Timbo where did this come from ? After a reply i will not ask any more questions !

[timbo003] 10/8/2022 21:29

>>>HTG

Looking at the chart it looks as if the all time high occurred during Oct 2009 and was about 17p/old ordinary share or 850p/new ordinary share

[haroldthegreat] 10/8/2022 20:18

Thank you Trev for pointing out my error . I took the 5 from 50 by error instead of 400. ! was rushing out at the time .!
Anyway even with the rise today , amazing what a little viagra dose to a share chart ,the correct calculation still is not enough to cure my depression over the massive loss !
So I will have to get some sertraline ,benzodiazepine and alcohol to get to sleep tonight .
The peak appears to have been $20 29/3/2018 but it might have been higher .

Tim another challenge what was the peak price ?

[boystown] 10/8/2022 19:56

Many thanks again timbo003. I guess the potential market is pretty much limitless if they get a genuine breakthrough - so I'll make that a "hold"! :-)

[timbo003] 10/8/2022 18:59

>>>>Boystown

The results from ENHANCE2 were really very good and exceeded my expectations (and probably the expectations of many others, including KOLs)

The exacerbation data (42% reduction) was particularly impressive and this was an improvement vs Standard of Care (LABAs, LAMAs and Steroids) not just placebo.

Others have found it difficult to show reduction in exacerbations, here's just two examples (there are others)

Novatis had to combine data from three large clinicals to get a statistically significant difference for Indercaterol plus SOC vs SOC


Takeda failed to show a significant difference with roflumilast in another large study (roflumilast plus SOC vs SOC)

[tradertrev] 10/8/2022 18:17

HTG - one ADS = 400 old shares
$11 / 1.2 / 400 = 2.29p ... that's already a 38% increase on your 1.66p!!

[boystown] 10/8/2022 17:12

Many thanks timbo003, but it's all Greek to me. Actually, it's worse as I could Google translate Greek! :-)

But a $588m market cap!? Is the Ensifentrine copd drug treatment potential that big? I mean, I know the market is immense, but is Ensifentrine genuinely groundbreaking?

[haroldthegreat] 10/8/2022 12:26

Ignorance is bliss !

[haroldthegreat] 10/8/2022 12:25

so 1 share = £8.30 = 500 old shares so valuing each old share at 1.66 p . Just as well I haven't done the calculation before , too depressing !
I was going to thank you for the information but would have been emotionally better off not to have picked your brains !!!!!

[timbo003] 10/8/2022 11:18

The last two investor presentations are worth a look to help understand the current state of play with respect to size of the opportunity, current startegy and ongoing clinical trials:

June 2022:

Aug 2022:

[timbo003] 10/8/2022 10:33

HTG

Old ordinary converted to new ordinaries through a 1 for 50 in 2017

1 ADR = 8 new ordinary shares

So 1 ADR = 400 old ordinary shares

[tradertrev] 10/8/2022 07:38

They are out with a 10m ADS issue which will be (maybe already has been?) underwritten. Almost certainly what caused the turn round in the price yesterday.
This should extend the cash runway well into and possibly beyond 2024 when Ensifentrine could be on the market.
There also cash milestones to come from China at some stage.

[haroldthegreat] 09/8/2022 19:53

Thank you Tim for removing the UK charts so fast ! Within the hour ! Now lets see how fast you can come up with the calculation !
Perhaps at 20:00 someone gave a small dose of Cialis I have noted the price has very slightly risen !

[haroldthegreat] 09/8/2022 19:46

How about the value in UK in £ ( or pennies ) on transfer plus details of the consolidation etc . Another task for you Tim I think ! We need an expert to work on this !

[boystown] 09/8/2022 19:30

I'd pretty much given up on these and have no idea how to value them. It's been so long now with so much dilution that I can't remember the potential valuation I put on them. I just remember reading a detailed post and analysis about nine years ago that seemed to make sense!

So ... can anyone who at least vaguely knows what they're on about here pin the tail on the donkey and say what these could / should be worth?

Thanks in advance.