Synairgen Share Discussion Threads

[dave444] 21/3/2020 15:17

A big plus for this share is only 44.2% of shares are deemed to be in public hands!22m trades in last 2 days average 11m bought and 11m sold out of 48m available in public hands!This indicates to me that we could have a severe upward squeeze if there is any positive announcement on Monday

[no1larafan] 21/3/2020 14:35

It's in the polish news as well! :-)https://pharmatrends.pl/nowy-lek-sng001-na-covid-19-w-brytyjskich-szpitalach/

[yet another final] 21/3/2020 14:09

My thoughts... Re share price movements, and all things being equal, anticipate a early morning spike of 20 to 30% followed by a 'usual' walk down to about low 50s then a gradual rising price closing around 60+/-5All bets off if new positive news available re SNG001

[lukead] 21/3/2020 14:07

Thanks again to you, all the best and yes I am another sport lover, football and cricket, tennis, so life is rotten with nothing to look forward to, even playing tennis is coming to an end for the present

[yet another final] 21/3/2020 14:03

Treatment is different from Cure

[yet another final] 21/3/2020 14:00

One is for diagnosis and the other is for treatmentNCYT is a diagnostic test, and is only as valuable as the government's strategy in dealing with crisis. I believe NCYT was going to be massive, had the government gone ahead and did mass testing to identify those with the virus (regardless of symptoms) and isolate them (put them in leper colonies) then we would not have had the rising numbers..... Anyway the opted to let the virus spread and hope people get immunity.... But that means people getting infected!!! So scope of diagnosis may have been curtailed (millions instead of 100s of millions) Treatment for Covid will require multiple agents depending on severity and symptoms. I believe that SNG001, with proven benefit in reducing viral load (see their website) will, once researched and approved, will be One of the important weapons in the treatment of the millions infected (as expected worldwide)..... Not the only one. A repeat of the images in Italian hospitals must be avoided, otherwise Healthcare will succumb in the developed world The anticipated benefit of SNG001, has forced the company to issue the following statement on their website.... "we have received a number of requests for SNG001 supplies to treat individuals outside the trial. As SNG001 is an experimental drug, untested as to safety and efficacy in this patient group, we regret that we are unable to fulfil any such request at this time."Such requests are not based on whimsical requests of random individuals, but based on the collective demand from leading clinicians. Given the perceived benefit of this inhaled drug, I anticipate that the company, whilst awaiting good clinical data from well designed studies, will actually make this drug available for "off-label" use on a named patient basis (this is frequently how some patients get the treatment before it is formally licensed) Apologies for the length of the comment, but I hope it is of use, and I am on lock down and bored with no live sport... I'm at risk of having a conversation with my wife!!!!!!

[nobbygnome] 21/3/2020 13:46

I would suggest just above 50p. I certainly hope it's not above 58p because I won't have enough to get my extra 1000 shares. I like round numbers so would really struggle to buy 950....

[bmnsa] 21/3/2020 13:45

What price will it cost me to top up on Monday morning.?BTW whatever it is l will still be buying,but will obviously get far less if it booms.

[nobbygnome] 21/3/2020 13:43

SNG have the right product at the right time and will make a fortune........if it works!

[lukead] 21/3/2020 13:42

Thanks for the prompt replies
So we have a)treatment, b) testing kit and c) vaccine ( a long way off)
Seems incredible that a treatment cure is a possibility

[likya123] 21/3/2020 13:36

Nyct has very good testing kits for covid-19 and supplying them globally.

SNG have a treatment for asthmatic (lung conditions) already past stringent tests which is currently also being trialled and fast tracked for covid-19 patients. If successful this will multi bag many many times from here.

Interestingly, ncyt just recieved FDA approval which will see it massively gap up on Monday morning and lots of fresh cash coming into here chasing a very very tight free float.

I believe we will see a three digit percentage rise both here and at ncyt on Monday.

[nobbygnome] 21/3/2020 13:34

You are comparing apples and pears. NCYT is making a test and SNG a treatment so completely different products. I know which one I would rather own shares in but each to their own.

[lukead] 21/3/2020 13:29

Forgive my ignorance, but I have just stumbled across this share and NCYT, the PM is talking about a vaccine in about 12 months time or longer.
Can anyone answer

1) Are both SNG and NCYT both testing for an actual cure to the virus, as opposed to a preventative medicine?

2) presumably both companies have merits, what are the main differences?

3) is it a case of buying both or is one better placed than the other?

Thanks

[bmnsa] 21/3/2020 13:01

No you cannot, it is set.

[hazl] 21/3/2020 12:36

well you can add to it...and you have used a question mark....

[hazl] 21/3/2020 12:35

'The biotech will begin a phase 2 trial in COVID-19, after an initial pilot phase

of the study involving 100 patients, which is set to take place across a number of NHS trusts and has also been adopted by the NIHR Respiratory Translational Research Collaboration.

“The UK life science ecosystem is stepping up across the piece on coronavirus. It’s fantastic to see a small UK biotech company, Synairgen starting UK clinical trials immediately on COVID-19,” commented Steve Bates, CEO of the UK BioIndustry Association.

"This shows the speed at which our ecosystem can move; linking SMEs, the established UK clinical trials infrastructure of the NHS and an enabling regulator in the UK’s MHRA.

“The sector is also working flat out on innovative emergent ventilator capacity, novel vaccine scale-up capacity, new ways to support NHS patients at home with digital products and investigating antibody technology for therapeutic use,” he added.'

[nobbygnome] 21/3/2020 10:41

LOL. But we could bin this one....

[yet another final] 21/3/2020 10:19

Noooo, too many threads for my simple brain

[nobbygnome] 21/3/2020 10:13

And afraid I can't change it now. In fact I really should start a different thread as I actually can't moderate on this one. However, I have now found out what sort of thread to set up to be able to do that so I might do that if it becomes necessary.

[nobbygnome] 21/3/2020 10:09

Yes it was a bit of artistic license and if you look back on the thread, I did admit that.

And yes happy to do that if they are persistent!

[yet another final] 21/3/2020 10:08

The title of this thread should not imply this is a CURE. (Nobby, you may be accused of exuberant ramping)
It is a treatment for something that is likely to be around for a while

Also can you ban any idiot that spams this board about NCYT ;)

[nobbygnome] 21/3/2020 10:05

They are running a trial in viral infection exacerbations of COPD at the moment. Since it stimulates the body's viral immunity it should work on just about any virus infection, hence the trial in Covid 19 infected people. There is lots of circumstantial evidence it should work such as they know that it activates the anti viral cells in the lungs.

That is how they got to this stage...

[2nell] 21/3/2020 09:55

Okay thanks for the answer.

Just trying to understand how they got to this stage.

[yet another final] 21/3/2020 09:54

PDT. 21 Mar '20 - 09:10 - 97 of 102

The real question is where SNG001 will sit in the spectrum of available therapies.
I believe it will be beneficial to people with 'significant' symptoms, as that correlates with actual extent of lung involvement. Unfortunately from a commercial point of view, on its own, this group may not be huge- only tip of the iceberg - (and I hope so as no one wants humanity to suffer).

The real potential, is in the rest of those infected (the rest of the iceberg)! If it is true that Covid causes varying degrees of 'silent' damage to the lungs (and as a result, problems in years to come, a la smoke related damage) AND SNG001 can prevent/reduce this, then "bang" this would be immense as all affected, regardless of symptoms would need treatment. Here's hoping.

Given the crisis in Italy, it would be ideal to consider emergency use/trial in the infected population, especially as there mortality is higher than most. Additionally, they are running out of oxygen (as daft as it sounds) so SNG001 could reduce O2 requirements