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Share Name | Share Symbol | Market | Type | Share ISIN | Share Description |
---|---|---|---|---|---|
Synairgen Plc | LSE:SNG | London | Ordinary Share | GB00B0381Z20 | ORD 1P |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.005 | 0.11% | 4.65 | 4.41 | 4.89 | 4.53 | 4.51 | 4.53 | 241,784 | 16:35:17 |
Industry Sector | Turnover | Profit | EPS - Basic | PE Ratio | Market Cap |
---|---|---|---|---|---|
Pharmaceutical Preparations | 0 | -17.65M | -0.0876 | -0.51 | 9.35M |
Date | Subject | Author | Discuss |
---|---|---|---|
23/7/2020 21:38 | That my dear 1gw is the key question.....which nobody here seems to know or understand. You tell me. I know because I discussed it with Richard Marsden..... | nobbygnome | |
23/7/2020 21:34 | And indeed, what is the Primary endpoint? The headline talks about Day 1 to Day 28 but the detail talks about change during the dosing period. "Primary Outcome Measures: 1. Ordinal Scale for Clinical Improvement [ Time Frame: Day 1 to day 28 ] Change in condition measured using the Ordinal Scale for Clinical Improvement during the dosing period - minimum of 0 (patient is well) to a maximum of 8 (death)" It may all be fine, but like I have said, today I was happy to walk away. | 1gw | |
23/7/2020 21:33 | >> 1gw I really don't think this is th investment for you......you are asking completely the wrong questions! | nobbygnome | |
23/7/2020 21:29 | Not sure if this as been posted just came across it mentioned in this interview https://youtu.be/BjK | fund1 | |
23/7/2020 21:29 | WE ARE ALL STARS. BELIEVE BIG BROTHER. VERY TRUE. ALL PLANETS ARE BORN FROM A DYING STAR. SO YOU CAN GO OUT AND TELL YOUR FRIENDS AND YOUR FAMILY BIG BRUTHA TOLD YOU, [YOU] A MEGA STAR. OUR BABY GOING SUPERNOVA 500P BY WEDNESDAY, ONCE WE ACHIEVE CRITICAL MASS AT 500P STELLAR EXPLOSION RACING WITH SUPERLUMINAL SPEED TO £20. WE ARE BUYING ALL THE WAY TO 500P. YOU HEARD IT FROM YOUR BIG BRUTHA. BB8 IN BB8 WE TRUST. | big brother8 | |
23/7/2020 21:25 | I was more nervous than sceptical, as an investor not knowing much about the company, sitting on a big short-term gain, reading some pretty negative (let's say sceptical) commentary from people who (I think) know a lot more about this than I do. If you look at the setup of the clinical trial (link below), both primary endpoint and all but one secondary endpoints involve comparing results at day 28 with results at the beginning of the study. Yet the press release focused on day 16 results (end of the treatment period). So if the study met its primary end-point, was the result statistically significant? If it was, why would that fact not be in the press release? And if it wasn't statistically significant, but the end-of-treatment results are statistically significant, what does that mean for the prospects of progressing from this Phase 2? | 1gw | |
23/7/2020 21:23 | 1gw "I happily admit to knowing very little about Synairgen" I'm not clinician but common sense says if something is destroyed by a virus and a drug replenishes it then the drug is doing it's job.. The fact it is inhaled means the drug goes direct to the root of the problem. so if you are low on Vit D and take Vit D tabs, they build up your Vit D.. That's my understanding... In terms of trials, there are millions of people in hospital. I don't think it be difficult recruiting patients for Phase III trials...It's better than the current situation of no treatment.. It's also safer than Mr Trump's solution to inject bleach into your body... again I'm no clinician but common sense says injecting bleach is dangerous!!. Crucially governments have already bought millions of doses of vaccines which are in trials, so there is a market... It doesn't guarantee the company will be a success but the results were a major step forward.. The risk is they may need a placing for Phase III and it's Covid dependent... | sikhthetech | |
23/7/2020 21:21 | If we receive conditional approval..do we have sufficient quantities and manufacturing capacity to service the gigantic nature of potential demand? | dovey21 | |
23/7/2020 21:20 | I also agree with Nobby, cannot see a placing to fund a Phase 3 going alone. This is a treatment that potentially SAVES LIVES, not like Remdesivir that just reduced hospital stay, yet got so much attention and FUNDING from US govt. this will be taken forward by a big pharma (licensing deal) or governmental org. It's too important to sit back with, as lives are at stake as we speak. As SNG said themselves: "Synairgen has been approached by, and is in discussion with, a number of other medical, scientific, and Governmental bodies (both in the UK, US and internationally) seeking to investigate novel therapeutics in this area." | spqstrader | |
23/7/2020 21:13 | I have to also add that I'm pretty confident about primary outcome results. Results already reported document a significant improvement by day 28 of treated patients odds of recovery (I assume as a binary endpoint as stated) compared to placebo. Bodes well for 28 day primary outcome measure with ordinal scale of recovery, doesn't it?Other secondary endpoints such as safety, tolerability etc already proven in previous asthma trials, so no surprises there. Small study - yes, but it makes these strongly positive results even more mind-blowing! | spqstrader | |
23/7/2020 21:08 | tidy 221 Jul '20 - 16:09 - 10718 of 11027 0 2 0 SNG001 is all encompassing and a natural protein your body produces naturally to kill viruses basically. Solves all respiratory virus infections etc ====== wot a fknLyngCnt!!!!!!!!!! | andymunchkin | |
23/7/2020 21:08 | 1gw, not sure why you're being skeptical about SNG? Pilot results are better than any other Rx out there, and Remedisivir has was given EUA 2 days after their results which are were really a damp squib.This is what the FDA said after the EUA. "From day one, the FDA has been committed to expediting the development and availability of potential COVID-19 treatments. Today's action is an important step in our efforts to collaborate with innovators and researchers to provide sick patients timely access to new therapies where appropriate, while at the same time supporting research to further evaluate whether they are safe and effective," said FDA Commissioner Stephen M. Hahn, M.D. "why wouldn't they give it to SNG001 when the pilot results are so much better? Watch this space... | spqstrader | |
23/7/2020 21:06 | gbh222 Jul '20 - 17:02 - 2940 of 2944 0 1 0 Leonard Licht,Halved his holding, that's one hell of a profit. | andymunchkin |
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