Scancell Share Discussion Threads

[chelsea35] 28/3/2018 04:20

Excellent post goosed, well worth a listen, and as an aside Richard Goodfellow attended that conference, not sure if accompanied though..................

"In the near term, we are going to see a significant, incremental progress in combining T-cell and antigen-based therapies with checkpoint inhibitors. But ultimately we need to be able to target multiple antigens in a meaningful time frame. In this T-cell space, the industry is going to face a number of challenges, starting with manufacturing issues to get to a deliverable therapeutic in a time frame that actually matters to the patient, and then with a product that is immunologically and therapeutically on target for an antigen that is exquisitely specific to the tumor," said Carter.""

"""IO is here to stay, it is not a bubble or a passing fad," said Khatereh Ahmadi, who is the Executive Director for Business Development and Licensing at MSD. "IO is so broad, spanning epigenetics to metabolism to microbiome, so there is yet a lot to explore for a while longer. We have taken a very empirical approach to this with more than 400 combinations and 700 trials."

Debi Watson, VP for Johnson & Johnson's Janssen Business Development Oncology agreed, saying, "We are so early in this space with our knowledge of what IO can bring to patients. We are at the very tip of the iceberg as to where this is going to go. If there is a bubble it concerns certain specific target areas where the upfront deals were incredible. As we move to the combination trials with companies generating data, we are still very much in the heat of that now. We have not even touched the potential in cold tumors or where vaccines can go. So IO is here to stay for a very long time. There is not one answer, not one patient population. There are a lot of variables to finding success and it will take time to figure it out."""

Making sure your posts find their way to the Scancell BB, interesting and relevant as ever. There are many who enjoy your posts over there. Hope you are good, ATB...........C7

[gooosed] 27/3/2018 22:37

&

"Asiya Giniatullina recently joined the investment firm Forbion coming from one of its portfolio companies, bluebird bio, where she worked for many years as senior research analyst. Her view is that gene editing on top of CAR-T and TCR approaches are taking the cell-based gene therapy field to the next level.

It is a big moment in the field with a better understanding of mechanisms and a critical mass of expertise. The opportunities in cell-based therapies are becoming interesting in the autoimmune space for an expansion beyond oncology, first to autoimmune-driven diseases that have a lot in common with the oncology mechanisms, and then beyond this into other indications where the immune system plays a role and can affect the outcomes," she said.



What did RG mean re "left field" ?

[gooosed] 27/3/2018 08:34

"However, new techniques built around engaging the immune response, such as CAR T cell therapies and cancer vaccines, are still being evolved and refined."



Lindy has, seemingly, spent a considerable amount of time refining Modi-1 (in dialing down on the ISA adjuvant etc.) - so Scancell should be announcing Modi-1 manufacture imminently . . . . ?!

[drdobson1] 26/3/2018 11:43

Had a short break after winning a Herbalife all ex’s paid trip to Torquay.
Don’t wish to start war of words but any comment against the logic of what Tosh and Loz have stated over ahT has happened here over the last few years.

[tosh 123] 26/3/2018 10:59

Indeed Loz... in fact, if you had hidden your £10k under your Grans bed 5 years ago, you would be at least 50% better off than you are right now had you of listened to certain idiots.

[gooosed] 23/3/2018 15:47

The typical British understated reserve perhaps needs an overhaul - time for the Scancell PR machine to receive an upgrade.

[the real lozan] 21/3/2018 13:21

Why - kids should not be allowed to play with guns....
Most 'intelligent folks' would KNOW the thoughts behind this 'thinking'
BUT
In the same vein -
Why - 'punters' should not 'play with trHYPE'
Most 'intelligent folks' would KNOW... NOT to follow the example of inane'n'co.. who HAS LOST 30% in just over a week - since HE bought at 19p = 12th March
AND
Several ill-timed 'punts' since
Only 2 days ago, HE was BUY,BUY,BUYing @ 15.2p
BUT
Twice as many THEN, as HE Bought today @ 14. 75p
.
Not ALL kids 'repeatedly', shoot themselves in the foot.... HE does

[the real lozan] 19/3/2018 11:44

Nob -
How's the CON creting going ???
The 'weather' YOU promised for us here in S W France has yet to arrive
Sunny, but not as warm as usual, for SPRING
.
Only a Nob that thinks HE CAN dictate to the markets, would "Go ALL in" with an 'ill-thought-out' plan to lay CON crete in the middle of winter.
Maybe, along with DICTATING to forums, markets - YOU thought YOU could DICTATE.. how the weather MUST behave too.
.
The REALISTS here, were thinking to BUY,BUY,BUY...YOU - a birthday present, But,*WE ALL* hit a 'stumbling block'----
What do you get, for a man 'who has .......
.... NOTHING' ???

[inanaco] 19/3/2018 11:04

Mid year we raised funds ... and RNS confirms future funds will be required

This funding could be provided either by a commercial agreement with a development partner, such as a large pharmaceutical company, or by further equity issuance to existing and/or new shareholders. The Directors believe that delivering the milestones outlined above will enhance the value of the Company and prepare it for further later stage fundraising. The Directors also believe that these milestones will ensure wider recognition of the Company both in the United States and Europe for the quality and value of both the ImmunoBody® and Moditope® platforms.

and here we are waiting the results of a collaboration agreement with BioNtech

and a possible deal with Roche ...

who knows, Lozan ?

lol .

[inanaco] 19/3/2018 10:58

I year ago ... so Loz can read an RNS ... and then claim a "Novel" post .. LOL
incredible performance ... wonder if the market priced that in ? interesting thought



The Board believes that further clinical studies could add significant value to the Company and is continuing to explore with its advisors a number of funding options to ensure that Scancell has the resources to progress these programmes further.



John Chiplin

Chairman (Jan 2017)



The increasing attractiveness of Scancell's products and technologies to pharmaceutical companies has to a large extent occurred as a result of the renewed interest in cancer vaccines as ideal partners for the checkpoint inhibitors, which although a major advance, only work in a minority of patients. Scancell is now in the enviable position of having not one, but two disruptive technologies in immuno-oncology and the Company is currently engaged in active discussions with several companies on both platforms. Closing a significant commercial arrangement with one or more of these companies would go a long way to underpin the value of these assets.

[the real lozan] 19/3/2018 10:48

Same old { few} trHYPERS -
Same old misguided trHYPE
-
Over a year ago, in another place, I posted =
21-02-17
"Since my last post here, the S P sat then at circa 15.63p {mid}.... Despite ALL the "Deals ANY DAY now' and other 'promises by the blind-faithers'.... S P now = ???. FUNDING still haunts this share."
.
Which prompted the silly misleader to infamously CLAIM - " FUNDING is NOT an ISSUE here"
.
First to mention {recently} =
FUNDING
"Deals any day" FAILURE to arrive
The effect of a - LULL in news
This 'set-up' and NEED ...and MENTION of a "PLACING"
.
All, met with derision by the {same old} trHYPE gang then ...
All, met with the REALITY now.
.
They would not listen
They're not listening still
Perhaps they never will

[chelsea35] 18/3/2018 05:31

Farmentally,

Amazes me, of all the posters on this BB who received bans from LSE years ago, I would say you deserved to go more than anybody else, the beauty of your history on LSE though is members there are revolted by you.

"""Chelsea,

Still a gutless fool - twisting words - 6 years later - FFS"""

Gutless eh!! Do you think that bothers me? You wouldn"t know the meaning of the word, believe me. Your selective use of this BB is gutless to the extreme.

As long as boom, goosed and a few others post here it is always worth catching up on though, and worth reposting to the LSE BB. So C7 still gets blamed for the bans handed out, only ADMIN can do that as you know, and the same old cries ""of the club" still dominates the rhetoric here, despite knowing full well one never existed as much as a buy buy scam ever existed, apart from a few long gone early posters. I suppose Calculas were part of the club too, along with Genentech, CRUK and others, not that you would have heard of any of them.

And yes, what are your views of the ""swimmers chart"", again not that you would derive any joy for the patients it represents.

I feel very sorry for newbies and those that drop into these pages to gauge more information behind our very welcome rise and science. It is my hope they find us on LSE to gain that information, rather than be subjected to the nonsense that goes on here. I was pleased to see Dr Dobsons post the other day, supporting a truce between us all. Unfortunately that will never happen, i think reading Lozans post the other day explained that very clearly.

There are boundaries that exist in all walks of life, they truly don"t reach as far as here. Your post to me is just further proof of that. ADVFN beats LSE hands down from level 2 to service to members, let down badly only by no monitoring of BBs, something which even LSE are now following, membership as per share chats continues to fall. The costs of trying to invoke rules must be too high to warrent it. It is more of a shame that grown men need monitoring, and behind the veils of anonymity behave as they do.

Many here would be very surprised at how many posters from LSE who rarely post are fighting cancer, just about the only ones i keep in touch with these days are them, as i struggle to keep in touch with even many in my own circles. Your post again last night on LSE, disgusted me and others as much as your post on here the other day.

Does it really give you the pleasure you seem to get, to see me and others suffer as we do?? Rubal and the late Melanoma Kid also felt a need to discuss it from time to time, it somehow explains where are posts are coming from. Timelines for me seem to be running shorter, you obviously read what awaits me tomorrow, it is not the money that drives me at all, i think we will steadily rise into the long term, with volatility increasing for traders to enjoy as well. I know who will benefit from my shares, and that pleases me as much as the progress Scancell are making ever does.

I would very politely ask you to refrain from the posts you are making to me, been no angel myself in the early years,, i just cannot understand any human being making them, and never will.

[farmertally] 18/3/2018 01:19

Chelsea,

Still a gutless fool - twisting words - 6 years later - FFS

[gooosed] 17/3/2018 09:35

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[inanaco] 16/3/2018 14:06

wrong ..

I was just hoping you would turn the leaf ...

ATB

sadly not ..