Optibiotix Health Share Discussion Threads

[riskybusiness1] 27/1/2019 18:20

With all existing deals, significant deal pipeline (eg sacco/China yoghurt launch), LPLDL going through FDA approval as a biopharmaceutical drug and is already covering its costs etc....you have to say Probiotix has been primed to fly and will be a significant valuable asset for the Optibiotix group.

[riskybusiness1] 27/1/2019 18:12

HLH in Germany originally were using AB life as the active ingredient within their Lactobact LDL control range. AB life is a cholesterol reducing probiotic containing multiple strains and pulls in around £6m+ revenues. HLH immediately dropped ABlife as the active ingredient, replacing it with a cheaper more effective single strain LPLDL. They even ordered LPLDL before Opti officially launched the product to industry.Italy is also the largest, fastest growing market within Europe for probiotics. It's a bit of a hub hence Sacco & Nutrilinea as a manufacturer/producer of the products. Alfa Sigma have signed a ten year contract with Optibiotix for LPLDL. They are one of the largest pharmaceutical operators within Italy and have serious penetration in these markets already with a probiotic called VSL. This probiotic pulls in over €40m. Opti will see revenues from the first orders from these larger deals coming through in 2019 as revenue growth continues to rapidly ramp up.

[parob] 27/1/2019 17:39

Any newbies looking in should have a listen to this CEO interview from Oct 2018. Note since then, Fred Narbel has been appointed, SlimBiome Medical was granted medical device status and given the CE mark and a further 5 deals have been struck! hTTps://tinyurl.com/y8z8d435

[incanus] 27/1/2019 17:05

High levels of cholesterol are commonly treated with statins, which are known to be associated with a host of undesirable side effects. CholBiome®, on the other hand, works by modifying the individual's current microbiome to offer a natural, scientifically-based solution with no known side effects.

RIGOROUS INDEPENDENT studies have shown LPLDL to:
Lower total cholesterol by up to 36.7%
Lower LDL cholesterol by up to 13.9%
Increase HDL cholesterol by up to 4.5%
Lower systolic blood pressure by 5.1%
Be completely safe and well tolerated

CholBiome® combines three targeted ingredients, Monacolin K from red yeast rice, Vitamin B3 (niacin) and Lactobacillus plantarum LPLDL® to deliver tangible health benefits.

[incanus] 27/1/2019 16:55

I wonder where these are based?

[riskybusiness1] 27/1/2019 15:55

Imagine paying £22 a month and using your time ticking people down and commenting on the same B.B. everyday outright lies, even on weekends. Not just a waste of money but a waste of time that could be spent far more wisely. Serious consideration should be put into deleting ADVFN Rayrac and putting that saved cash towards some counselling.See link below which is a BB clear of all agenda driven obsessed trolls and full of well sourced information and educated debate :https://groups.google.com/forum/m/#!forum/lemminginvestors

[rayrac] 27/1/2019 14:01

“Bulgaria has some of the highest mortality rates in Europe caused by cardiovascular disease accounting for up to 64% of all deaths (WHO).”

It’s because they can’t afford a diet that would help them. Why the heck they would go out and buy a tub of rolled oats at the equivalent or £2 ea, is a mind bender!

If it were that good a product, then try selling it to the German population ,who might just be able to afford it.

Oh, and slartyfartfaster, LPLDL doesn’t work effectively enough!

[slartybartfaster] 27/1/2019 13:42

Lactobacillus plantarum lpldl Abstract


Coronary heart disease (CHD) is one of the major causes of death and disability in industrialised countries, with elevated blood cholesterol an established risk factor. Total plasma cholesterol reduction in populations suffering from primary hypercholesterolemia may lower CHD incidence. This study investigated the cholesterol reducing capacity of Lactobacillus plantarum ECGC 13110402, a strain selected for its high bile salt hydrolase activity, in 49 normal to mildly hypercholesterolaemic adults. Primary efficacy outcomes included effect on blood lipids (total cholesterol (TC), low density lipoproteins (LDL-C), high density lipoproteins (HDL-C) and triacylgycerides (TAG), inflammatory biomarkers and occurrence/severity of gastrointestinal side effects to establish safety and tolerance of the intervention. Secondary outcomes included blood pressure, immune biomarkers, gut microbiota characterisation and metabonome changes. The study was run in a parallel, double blind, placebo controlled, randomised design in which the active group ingested 2x109 CFU encapsulated Lactobacillus plantarum ECGC 13110402 twice daily. Daily ingestion of the active treatment resulted in a statistically significant reduction in LDL-C in volunteers with baseline TC<5mM during the 0–12 week period (13.9%, P = 0.030), a significant reduction in TC in volunteers with baseline TC≥6mM in the 0–6 week period (37.6%, P = 0.045), a significant decrease in TAG (53.9% P = 0.030) and an increase in HDL-C (14.7%, P = 0.007) in the over 60 years population in the 6–12 week period. A statistically significant reduction in systolic blood pressure was also observed across the active study group in the 6-12-week period (6.6%, P = 0.003). No impact on gastrointestinal function and side effects was observed during the study. Similar to blood and urine metabonomic analyses, faecal metagenomics did not reveal significant changes upon active or placebo intake. The results of this study suggest that Lactobacillus plantarum ECGC 13110402 is a well-tolerated, natural probiotic, that may be used as an alternative or supplement to existing treatments to reduce cardiovascular risk.

It has pictures for stupid people.
hxxps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187964

[parob] 27/1/2019 13:33

This agreement is the first covering the CholBiome(R) range following our recent launch online in the UK and is the first step in our strategy to expand OptiBiotix's sales of CholBiome(R) own label products into the European market. Bulgaria has some of the highest mortality rates in Europe caused by cardiovascular disease accounting for up to 64% of all deaths (WHO).

[rayrac] 27/1/2019 13:08

How the heck can you sell such expensive non effective product, in Bulgaria of all poverty riven places?!

Should be ashamed of themselves at Opti.

[parob] 27/1/2019 08:35

Well AJS is another Columbo then. Some of the info I post on here is a repost of AJS’s amazing detective work in the twitter group.

Here is another Bulgarian Pharma site he’s found selling 'Cholbiome®X3'



Sure it won’t be long until Russian websites selling CholBiome are discovered.

[2350220] 26/1/2019 22:42

After all the detective work he's carried out, I'm convinced that Parob is really Columbo!
John

[judijudi] 26/1/2019 17:15

aster,
:)
:)
Amended

[asterix96] 26/1/2019 16:54

I didn't realise that Elrico was yours Judijudi!

[judijudi] 26/1/2019 16:07

Didn’t take long for the alleged Opti shareholder Dazah to return did it?
After he had his ear clipped by Elrico
:)

[parob] 26/1/2019 16:01

Business opportunities: Everyone wants a slice of the 'awesome' microbiome pie, says market analysthTTps://tinyurl.com/y8dy8emvAcquiring successVenkataraman adds that, in the past couple of years, the industry has witnessed a number of key acquisitions which show how valuable collaboration can be:  Kerry's acquisition of Ganeden, DSM's acquisition of BioCare, Nestlé's acquisition of Atrium Innovations, and ADM's acquisition of Protexin. "It's not easy to come up with consumer facing gut-benefiting products but if they can know who to partner with, such as a start-up doing microbiome-based analysis, they can combine their knowledge to create a great business opportunity."We expect to see more investment activities around the probiotics space by players both upstream and downstream the food value chain in a bid to expand their health and wellness offering."

[rayrac] 26/1/2019 14:23

Any port in a storm eh Parob?

Fine thanks dazah, despite having to plough through the dodgy muesli! Not lost any weight tho. Rather than feeling full, I feel I’ve been conned. :(

[scotty1] 26/1/2019 14:18

dazah26 Jan '19 - 13:12 - 45871 of 45872
0 0 0
You on the whackey baccy again Parob???

I understand doctor has legalised it?

Afternoon Rayrac hope you're well mate.

------------------------------------------------------
That post is about as useless as this one.
Second line does not need a question mark as it is not a question
and as for the third line,well do you know how pathetic you sound ?
Grow up laddy.

[parob] 26/1/2019 13:31

The Wellness Trends You Can Expect to See Everywhere in 2019



You Can Find Probiotics in the Chip Aisle
They're not just in yogurt anymore. It seems like everything is being enriched with creepy crawlers these days. According to a Google Trends analysis, there was a 350-percent increase in searches for "best foods for gut health" between 2012 and 2017, and while the probiotic market was valued at $40.09 billion in 2017, it's expected to generate revenue of around $65.87 billion by end of 2024.

Not surprisingly, food manufacturers are taking notice, pumping the live active bacteria into everything from chips to granola to bars.

[dazah] 26/1/2019 13:12

Looking good today.