Motif Bio Share Discussion Threads

[regandharry5] 06/6/2019 10:34

I was laughed off this board a while back for saying the fund raising would be at 2p. He who laughs last, laughs longest.

[pugugly] 06/6/2019 10:27

log: Very fair comment (imo)

[loglorry1] 06/6/2019 10:19

I'm sorry guys but this looks terminal. As has been pointed out Motif need to raise to fund more trials AND support their own cash burn. This isn't going to be cheap at all. Further who would give them money given the repeated failure to pass trials by this drug? Even if they do raise at say 2p the amount required would result in homeopathic dilution to holders.

I am short here but I'm not covering at current levels as I think the price is pretty much a zero. Anyone buying here is mad - at least buy in the placing which we know is due as they've said they only have cash until June.

Also one does wonder why the hell they sat on this news for so long when it should have been put out in the market. Perhaps to let insiders sell? We saw a spike down yesterday afternoon so news had obviously leaked forcing the disclosure. That doesn't bode well for trustworthy management.

It was a punt on the long side to see if they got approval but that's not happened here as is so often the case with AIM shares.

[apfindley] 06/6/2019 09:52

26th March they raised 2.7million.In the statement they clearly wrote"The net proceeds from the Placing, when taken together with the Company's existing cash resources, are expected to be sufficient to fund the business beyond the expected receipt of the FDA meeting minutes in June."So stop lying letmepass.

[letmepass] 06/6/2019 09:48

Money not for a while they have sufficient funds for a year

[apfindley] 06/6/2019 09:43

Long delays now for another trial to be organised.Will add a year or more.And meanwhile the company have already told you that they require urgent funding.

[letmepass] 06/6/2019 09:37

Positive coming at 1pm..load up

[hoggar] 06/6/2019 09:07

The finger of Morgan strikes again! This new extension with Motifs fortunes should see the end of Morgan and his fat cat ambitions with Amp. Once amps 6% holding in Motif has gone to pay off debts, investors will see a marked recovery in Motif's fortunes.

[buywell3] 06/6/2019 09:05

How many shares do you hold in this POS qaz ?

Waht do you think a Phase 3 clinical trial will cost that will have to be done to FDA very strict requirements now that they have just failed the compound yet again ?

[volsung] 06/6/2019 08:46

Tbh not much point in me panic selling here. Lets see what the company says

[qazwsxedc69] 06/6/2019 08:43

Exactly - It could be small. We don't know. Except the idiot buywell who knows that it will cost $30m because he is an idiot. All is not necessarily lost here.

[pugugly] 06/6/2019 08:42

Over 10 million shares traded so far - That is not PI's - Looks like at least one II has decided enough is enough and is cutting losses - Down 44% - Company valued at less than say 50% of funding required.

[obiterdicta] 06/6/2019 08:40

It could be a very small trial required with a subset of patients or a complete re-run. Might find out more on call.

[nick rubens] 06/6/2019 08:39

So now it's been revealed what the FDA issues were when approval wasn't granted a few months back.

"continued concerns about potential liver toxicity."

Did the company know this back then?

[qazwsxedc69] 06/6/2019 08:36

"Phase 3 trial costs circa $30M"

Astonishing levels of ignorance there, from someone who......always displays astonishing levels of ignorance. Filter.

[volsung] 06/6/2019 08:20

Somebody sees value in these or they would be down 80%+

[buywell2] 06/6/2019 08:17

Have you checked the price of these now ?

Phase 3 trial costs circa $30M now

I put phase 2 for reference as some may be invested in similar stocks

Raising cash if this bombs to 3p will mean that most PI's will get wiped out IMO

but

dyor

ah 4p and as predicted a leading place on the advfn losers board cometh

Bulls

The floor is yours

[bountyhunter] 06/6/2019 08:03

Don't be daft, and it's a single trial to evaluate any liver toxicity not the plural as in your previous posts. As bocase says the antibiotic works and the world is short of new ones. Many currently used antibiotics have some liver effects this just needs to be evaluated to provide the further data requested.

[buywell2] 06/6/2019 08:00

Something is bocase , agreed , but not this compound

It needs re-formatting ie start all over again

And to do that the particular molecule/s within the compound that have caused DILI need to be identified and removed.

[bocase] 06/6/2019 07:56

On the other hand, it is desperately needed to combat bacterial resistance.

[buywell2] 06/6/2019 07:49

In 2016 the average cost of a Phase 2 clinical trial ranged from $7.0 million to $19.6 million, while the average costs of phase 3 clinical trials ranged from $11.5 million to $52.9 million.

Add 15% to the above = too expensive for MTFB IMO at this point


Don't forget this drug compound has failed before for the same reason, twice I believe from memory

It has been talked about on here a few times but wasn't accepted by all the resident bulls

IMO the market won't like this RNS and this share could appear on the advfn loser board, perhaps then the bulls /rampers will admit they were wrong.

Drug Induced Liver Injury is one of the 2 main issues that gets FDA approved drugs withdrawn

Which clearly demonstrates that the pre - clinical trails mandated by the FDA are useless

Toxicology and Acute Toxicology pre clinical in particular using animals .... absolutely stupid

dyor

[nico115] 06/6/2019 07:40

3pAnother trial bad news Costs too much What a shame,thought would just be a labelling issue Sorry for all holders here