Immupharma Share Discussion Threads

[divinessence] 18/5/2018 09:57

If you are sincere and ethical then you would want the trial and further data analysis to continue if it could help the Lupus sufferers particularly as there are no side effects, no negative impact on the immune system and chance of a cure and possibly remission. Yes, statistically the drug did not pass the endpoints but doesn't mean it doesn't work or cannot be enhanced, especially as there is nothing else on the market with comparable safety record. To boot it out of the 'cupboard' without a recourse is touch unethical and insincere particularly coming from those who have other agenda. This much is obvious from negative repetitive posts from one or two here. We know who they are,.

Here's to hope for all and let the trial and full data analysis to continue. Still in and still positive.

[wigwammer] 18/5/2018 09:39

Hmmm. A finger pointing shouty person with nothing to say about the company or its assets. Where have I heard that before? :)

[bmcb5] 18/5/2018 09:36

You were suggesting a price of £30/share. That turned out to be incorrect too, didn't it?

[wigwammer] 18/5/2018 09:34

Bmcb. Thanks for conceding that the bear made an incorrect point. No one is shouting at the bear so please leave the rhetoric and morality in the cupboard (though there wouldn't be much of a post left). Go enjoy the sunshine, I am :)

[obiterdicta] 18/5/2018 09:29

The premise of NG's argument is that as Lupozor failed to reach statistical significance there should not be an OLE as that gives sufferers false hope and is unethical as the drug does not work.

The counter-argument is that whilst statistical significance was not achieved in the trial the OLE may be clinically useful if the data shows efficacy, in particular remission and reduction of symptoms. I am not sure patients would find it unethical to take Lupuzor in the OLE and then either go into remission or have a reduction in symptoms. Given there are no harmful side effects, if all parties want to continue where is the harm?

OD

[wigwammer] 18/5/2018 09:29

Nobby - they haven't seen the full data. It may be that those who have a fuller understanding of the data want the trial to continue, whether there is a mechanism to stop it or not.

[nobbygnome] 18/5/2018 09:25

What I don’t understand is why che sets so much store by what Tim says. He had proved to be spectacularly inept so far and failed to deliver a positive result due to naivety. What is the saying about making the same mistake twice and madnes....

[bmcb5] 18/5/2018 09:24

You all shout at the bear, as though he's the dangerous one.

Rampant bulls are the real danger in this game. The ones who make you feel like you've just found the next surefire bet. The ones who get you excited to buy more, before it rockets to the stars. They're the ones to be very wary of.

imo

[wigwammer] 18/5/2018 09:23

Bmcb. He made a claim which turned out to be wrong. Fact. I am not suggesting banning nobby. Fact. Regarding profit here, depends what your entry and exit price has been. Fact. Apart from that - great post :)

[nobbygnome] 18/5/2018 09:20

>> wiggy

The people I asked all had nothing to do with Lupuzor. I just gave them the scenario and asked what they thought. All of them said it was unethical to continue the OLE. I think that is very clear and irrefutable but as I say because of an apparent flaw in the system unless IMM decide to take the honourable course in Europe at least, the trial will continue.

Nobby

[bmcb5] 18/5/2018 09:19

He offered a suggestion, which didn't turn out to be accurate?

Wow. Ban him from these boards!

What about all the suggestions that this trial would be successful? They're the ones which have actually cost people money - and made by people with their own motive

Anybody who panicked and got out of this will now have more capital than they would by staying in. Fact.

[wigwammer] 18/5/2018 09:11

David - it is possible, though I've been on these chat boards a long time and most people 100% talk their own position/motive. Whether nobby was talking out of the goodness of his heart or otherwise, when he suggested after the trial result that the extension trial would be stopped, he wasn't offering accurate information. He was also making the claim, I'm sure out of the goodness of his heart, when he knew people would be easily panicked.

[njb67] 18/5/2018 09:08

david

Indeed. I would pay much more attention to NG than anything that Tim says.

IMM will slowly but surely run out of cash. Even if Lupuzor can be resurrected, that is a big if btw, they will not be able to fund the necessary trials without a partner nor a massive fund raise. They would need to raise more than their current market cap.

Given the trial results to date - various failed studies - and how they were conducted, any pharma interest here would be at the seriously speculative end of the spectrum.

From an investment perspective, the best we can hope for is a fire sale of assets. The more likely scenario though is that this will go the same way as many fledgling pharma companies, bust.

[che7win] 18/5/2018 09:06

david,
Can I suggest you ask the company what is going on - that might help you see both sides.

[wigwammer] 18/5/2018 09:04

Thanks nobby - so when you suggested early after the trial result that the extension trial would be stopped, that was based on an incorrect premise. You state you have "spoken to a number of people in the industry". Can I suggest anyone acting on that advice may also be working on an incorrect premise (that these people have anything to do with the future of lupuzor).

[davidh2133] 18/5/2018 08:49

Has it occurred to anyone else on here that Nobby is in fact 100% genuine and sincere, with good knowledge of the science, trial design and how the industry and regulator works and he's just trying to warn us all so we don't lose more money than we already have?

[nobbygnome] 18/5/2018 08:43

Don't worry, I am still here😜.

To reply to Wiggy about the OLE. The MHRA got back to me and said they would only consider the ethics if they submit a new trial application and it seems there isn't a mechanism for examining ongoing trials. I have spoken to a number of people in the industry in the last few weeks and to a man and woman they all agreed it was unethical to continue. So it seems there is a fundamental flaw in the system which is allowing it to continue.

And the FDA are still considering the matter.....

Nobby

[rnsday] 18/5/2018 08:25

Don't be daft nobby gone he will be here soon if there is a rise .... it's a dud dead in the water

[crapcrap] 18/5/2018 08:23

can i sense a wind of change? aviva gone Nobbygnome gone?

[rathean] 17/5/2018 22:08

Got a buy in trigger at sub-23, no point trading on a 3p and narrowing channel. Awaiting anything from the bod.

[escapetohome] 17/5/2018 20:10

Almost back down to 2015 low, i would try and snag some at that price, around 22p.

[coldspring] 17/5/2018 17:42

I am waiting for news on the data review and who, if anyone, is interested. Until then it's just noise. GLA