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| Share Name | Share Symbol | Market | Type | Share ISIN | Share Description |
|---|---|---|---|---|---|
| Cizzle Biotechnology Holdings Plc | LSE:CIZ | London | Ordinary Share | GB00BNG2VN02 | ORD 0.01P |
| Price Change | % Change | Share Price | Shares Traded | Last Trade
|
|
|---|---|---|---|---|---|
| -0.075 | -4.35% | 1.65 | 638,101 | 09:49:15 |
| Bid Price | Offer Price | High Price | Low Price | Open Price | |
|---|---|---|---|---|---|
| 1.60 | 1.70 | 1.725 | 1.65 | 1.725 | |
| Industry Sector | Turnover | Profit | EPS - Basic | PE Ratio | Market Cap |
|---|---|---|---|---|---|
| Coml Physical, Biologcl Resh | -1.72M | -0.0043 | -3.84 | 6.84M |
| Last Trade Time | Trade Type | Trade Size | Trade Price | Currency |
|---|---|---|---|---|
| 15:53:39 | O | 1,000 | 1.6475 | GBX |
| Date | Time | Source | Headline |
|---|---|---|---|
| 02/1/2025 | 14:29 | ALNC |  IN BRIEF: Cizzle Biotechnology appoints Founder Dawn Coverley as CSO |
| 02/1/2025 | 07:00 | UK RNS | Cizzle Biotechnology Holdings PLC Appointment of Professor Dawn Coverley as.. |
| 16/12/2024 | 07:00 | UK RNS | Cizzle Biotechnology Holdings PLC Update on Strategic Partnership in North.. |
| 21/10/2024 | 06:00 | UK RNS | Cizzle Biotechnology Holdings PLC Execution of Agreement for North America |
| 03/10/2024 | 12:12 | UK RNS | Cizzle Biotechnology Holdings PLC Update on Licensing and Partnership.. |
| 30/9/2024 | 17:37 | ALNC | EARNINGS: Alliance Pharma swings to profit; DG Innovate loss widens |
| 30/9/2024 | 06:00 | UK RNS | Cizzle Biotechnology Holdings PLC Interim Results |
| 16/9/2024 | 06:00 | UK RNS | Cizzle Biotechnology Holdings PLC Holding(s) in Company |
| 09/9/2024 | 21:03 | ALNC | TRADING UPDATES: Light Science Technologies wins two new contracts |
| 09/9/2024 | 06:00 | UK RNS | Cizzle Biotechnology Holdings PLC Collaboration with Moffitt Cancer Center |
Cizzle Biotechnology (CIZ) Share Charts1 Year Cizzle Biotechnology Chart |
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1 Month Cizzle Biotechnology Chart |
Intraday Cizzle Biotechnology Chart |
| Date | Time | Title | Posts |
|---|---|---|---|
| 06/2/2025 | 17:01 | Cizzle Biotechnology 2023 and Beyone | 416 |
| 14/12/2023 | 07:55 | Cizzle Biotechnology Holdings PLC | 2,205 |
| 02/10/2023 | 07:07 | Cizzle Biotech | 498 |
| Trade Time | Trade Price | Trade Size | Trade Value | Trade Type |
|---|---|---|---|---|
| 2025-02-06 15:53:40 | 1.65 | 1,000 | 16.48 | O |
| 2025-02-06 14:27:03 | 1.65 | 14,778 | 243.82 | O |
| 2025-02-06 14:05:42 | 1.65 | 25,000 | 412.25 | O |
| 2025-02-06 13:30:38 | 1.65 | 17,000 | 280.33 | O |
| 2025-02-06 13:25:42 | 1.65 | 24,257 | 400.00 | O |
| Top Posts |
|---|
Posted at 06/2/2025 08:20 by Cizzle Biotechnology Daily Update Cizzle Biotechnology Holdings Plc is listed in the Coml Physical, Biologcl Resh sector of the London Stock Exchange with ticker CIZ. The last closing price for Cizzle Biotechnology was 1.73p.Cizzle Biotechnology currently has 396,390,000 shares in issue. The market capitalisation of Cizzle Biotechnology is £6,540,435. Cizzle Biotechnology has a price to earnings ratio (PE ratio) of -3.84. This morning CIZ shares opened at 1.73p |
Posted at 31/1/2025 14:11 by dannymaz89 Https://www.medrxiv. |
Posted at 19/1/2025 14:33 by dannymaz89 https://www.cizzlebi |
Posted at 14/1/2025 12:35 by dannymaz89 #CIZFirst laboratory contract: BIO has executed its first and confidential agreement with a CAP approved clinical laboratory and intends to register the CIZ1B biomarker as a CLIA accredited test in January 2025 with plans for commercial launch in April 2025.?"The Group already has a further licensing deal in China which is being progressed as the supply of the Company's commercial antibodies increases. The programme will commence after the first laboratory in the US has achieved CLIA accreditation.""Succ |
Posted at 07/1/2025 13:17 by dannymaz89 Bit of background Lung cancer is the biggest killer of the cancers, Why big d?Because you only realise when you cough blood (symptomatic) this is stage 3What's stage 3 big d?10% survival, unfortunately p10Ciz1b can be detected at stage 1, a grain of rice cancer simple operation But what about scans big d?Ultrasound, mri, ct scan ... £10k... and still don't know until swabbed. CIZ test £50-100 lateral flow 10 minutes |
Posted at 18/11/2024 10:11 by m_night10 POLX Polarean Imaging 1.6p I fancy to fill the gap to 3.2p and head to 10p+. Mcap is peanuts and cash position is much longer to Q2 2026 and revenue are higher and growing even more quickly than this.. I see it as a steal for the FDA approved Xenon MRI. No company debt, masssive growth potential in the worlds biggest health market the United States where it's already in 21 clinical settings, best in class next generation MRI. Revenues rising up 3000% to $3mil for 2024 and doubling again next to $6mil in 2025 Cash runway to minimum of Q2 2026, looks set to be extended given revenues ahead of expectations.Putting this UK recovery play potential on radars as used to trade at 100p and has made significant commercial progress since FDA approval. Massive takeover target and will be sold for 20p+ share price. 1. September 18th 2024: Interventional radiology vendor Merit Medical to acquire device portfolio for $210M. APPROX 13P SHARE PRICE EQUIVALENT FOR POLX 2. September 25th 2024: Private equity firm acquiring diagnostic imaging provider for $658M APPROX 48P SHARE PRICE EQUIVALENT FOR POLX 3. October 14th 2024: Hologic to Acquire Gynesonics The women’s health company will be purchased for approximately $350 million. APPROX 22P SHARE PRICE EQUIVALENT FOR POLX 4. Bracco current major TR1 Holder of Polarean splashed out $450MILLION for a diagnostic buyout POLX easy buyout target more massive premiums as per the above imv. DYOR, not advice. |
Posted at 08/12/2023 21:40 by oapknob1 Owed them ? Previously posted So CIZ paid out £255,000 cash for economic interest in AZD1656. Then get paid £200,000 by SGSC so £55,000 paid out and the 5% interest was settled with issuing shares in CIZ to a value of £1,880,000. They executed the put and received £3,250,000 worth NASDAQ shares in CDT at $10 a share. Whats terrible ? (Other than current CDT share price)20 September 2021"SGSC to grant Cizzle Biotechnology potential future royalty payments from the commercialisation of St George Street's therapeutic asset AZD1656 of up to GBP5 million, plus potentially further payments from the use of a companion diagnostic.""Under the full commercial contract entered into, in consideration of the potential future royalty stream from the commercialisation of AZD1656 , Cizzle Biotechnology is to pay GBP135,000 to SGSC."22 October 2021"Research and Development agreement worth up to GBP1 million signed for potential autoimmune disease testing and possible additional companion diagnostics.""SGSC will pay Cizzle Biotechnology GBP200,000 upfront on commencement of the project and then further milestone payments totalling up to GBP1 million. "14 February 2022Agreement with Conduit and SGSC to acquire a 5% economic interest for a total consideration of GBP1.88 million, to be settled in new Cizzle ordinary shares at a price of 4.0p per share, a 56.9% premium to the closing mid-market price on 11 February 2022"The Agreement is in addition to the Company's existing interest in AZD 1656 as announced on 20 September 2021"29 September 2022has settled the remaining consideration of GBP880,000 due under the Agreement through the issue of 22,000,000 new ordinary shares of 0.01 pence each ("Ordinary Shares") in the Company at 4.0p per share (the "Agreement Shares") to Conduit.19 December 2022"Put Option for Sale of Economic Interest and Royalty Sharing Agreement in AZD1656""Cizzle has agreed to pay Conduit GBP120,000 in cash as the premium for the Option" |
Posted at 02/12/2023 17:04 by oapknob1 So CIZ paid out £255,000 cash for economic interest in AZD1656. Then get paid £200,000 by SGSC so £55,000 paid out and the 5% interest was settled with issuing shares in CIZ to a value of £1,880,000. They executed the put and received £3,250,000 worth NASDAQ shares in CDT at $10 a share. Whats terrible ? (Other than current CDT share price)20 September 2021"SGSC to grant Cizzle Biotechnology potential future royalty payments from the commercialisation of St George Street's therapeutic asset AZD1656 of up to GBP5 million, plus potentially further payments from the use of a companion diagnostic.""Under the full commercial contract entered into, in consideration of the potential future royalty stream from the commercialisation of AZD1656 , Cizzle Biotechnology is to pay GBP135,000 to SGSC."22 October 2021"Research and Development agreement worth up to GBP1 million signed for potential autoimmune disease testing and possible additional companion diagnostics.""SGSC will pay Cizzle Biotechnology GBP200,000 upfront on commencement of the project and then further milestone payments totalling up to GBP1 million. "14 February 2022Agreement with Conduit and SGSC to acquire a 5% economic interest for a total consideration of GBP1.88 million, to be settled in new Cizzle ordinary shares at a price of 4.0p per share, a 56.9% premium to the closing mid-market price on 11 February 2022"The Agreement is in addition to the Company's existing interest in AZD 1656 as announced on 20 September 2021"29 September 2022has settled the remaining consideration of GBP880,000 due under the Agreement through the issue of 22,000,000 new ordinary shares of 0.01 pence each ("Ordinary Shares") in the Company at 4.0p per share (the "Agreement Shares") to Conduit.19 December 2022"Put Option for Sale of Economic Interest and Royalty Sharing Agreement in AZD1656""Cizzle has agreed to pay Conduit GBP120,000 in cash as the premium for the Option" |
Posted at 21/9/2023 17:12 by smithie6 No one in their right mind would have a short open in this...which is dependent on the price movement tomorrow of a medical company listing/merger on Nasdaq....the price on Nasdaq could do anything At any time tomorrow afternoon in the UK, CIZ could issue an RNS saying that it has exercised it's option in Conduit & sold all its shares & has obtained X million $ which converts to Y million £ & such an RNS could cause the CIZ share price to move to T pence. No one in their right mind would short such a situation. And of course shorting any company with a cap. value of <10 million is usually madness, especially a medical company trying to create product(s) in the cancer sector. If a tiny medical co. announces "success" then the share prices can go nuts in minutes. |
Posted at 22/3/2023 09:22 by oapknob1 Sooner MURF and Conduit conclude the merger and NASDAQ listing the better for underpinning CIZ share price at these levels. |
Posted at 16/3/2023 15:22 by smithie6 there is a 3rd RNS about CIZ & deals with Conduit/SGSA14th Feb. 2022 Cizzle Biotechnology Holdings PLC 14 February 2022 This announcement contains inside information for the purposes of article 7 of EU Regulation 596/2014 which forms part of domestic UK law pursuant to the European Union (Withdrawal) Act 2018 ("UK MAR") . Upon the publication of this announcement this inside information is now considered to be within the public domain. 14 February 2022 Cizzle Biotechnology Holdings Plc ("Cizzle Biotechnology", "Cizzle" or the "Company") Acquisition of Royalty Deal in Inflammatory Pulmonary and Cardiovascular Diseases Cizzle Biotechnology, the UK based diagnostics developer, is pleased to announce that it has entered into a definitive agreement (the "Agreement") with Conduit Pharmaceuticals Limited ("Conduit") and St George Street Capital Limited ("SGSC") to acquire a 5% economic interest in the commercialisation of the AZD 1656 asset or other such assets being developed by Conduit or SGSC to treat inflammatory pulmonary and cardiovascular disease (the "Economic Interest"). Highlights -- Agreement with Conduit and SGSC to acquire a 5% economic interest for a total consideration of GBP1.88 million, to be settled in new Cizzle ordinary shares at a price of 4.0p per share, a 56.9% premium to the closing mid-market price on 11 February 2022 -- The Agreement is in addition to the Company's existing interest in AZD 1656 as announced on 20 September 2021 -- SGSC recently reported the successful completion of the AZD 1656 ARCADIA clinical trial in Covid-19 and SGSC and Conduit are in discussions with multiple pharmaceutical companies about licensing opportunities for AZD 1656 for Covid-19 and potentially for further indications -- The Agreement supports the Company's ambitions to expand its target customer base into the pharmaceutical industry and is in line with its strategy of building a portfolio of early cancer detection tests, companion diagnostics and royalty bearing stakes in significant drug assets Allan Syms, Executive Chairman of Cizzle Biotechnology, said "The agreement announced today represents an important extension to our close relationship with SGSC and Conduit. On 20 September 2021 we announced we had acquired a stake in SGSC's AZD 1656 asset, providing the opportunity for the Company to receive royalty payments of up to GBP5 million and shortly after SGSC contracted the Company to develop an associated companion diagnostic test for which we will receive fees of up to GBP1 million. "We are now pleased to have the opportunity to increase our stake by an additional 5% in AZD 1656, but significantly the Economic Interest will be uncapped. This new Agreement supports the Company's ambitions to expand its target customer base in the pharmaceutical industry and through a strategy of building a portfolio of early cancer detection tests, companion diagnostics and royalty bearing stakes in significant drug assets significantly increase shareholder value." Background SGSC is a UK-based medical-charity led by a group of highly decorated academics and ex-pharma executives formed to deliver much needed treatments to patients. SGSC's strategy is to take clinical-ready assets from pharmaceutical companies and to progress them through Phase II medical trials, before licensing them on for Phase III trials and commercialisation in order to create a return for investors and the charity alike. SGSC recently reported the successful completion of the AZD 1656 ARCADIA clinical trial in Covid-19 and SGSC and Conduit are in discussion with multiple pharmaceutical companies about licensing opportunities for AZD 1656 in both Covid-19 and potentially in further indications. Conduit is the exclusive funding partner to the Charity. The ARCADIA trial data, that treated inflammatory pulmonary and cardiovascular disease caused by Covid-19, showed a strong trend towards reduced mortality in patients receiving AZD 1656. The strong trend to improved mortality for patients on AZD 1656 was observed on top of patients receiving other medication as part of standard of care. AZD 1656 was also shown to be well-tolerated in this patient population with no serious adverse reactions (SARs) occurring. Overall, no safety concerns were identified regarding the use of AZD 1656 in this patient population. Furthermore, SGSC has shown there was a significant increase in the migration of the Regulatory T Cells ("Tregs") from the patients who had taken the drug compared to the Tregs from the patients who had not. Tregs are a specialised subpopulation of T cells that act to suppress immune response and combat damaging cells, potentially reducing serious cardiovascular and lung diseases which are causative in the development of lung cancer, which Cizzle is developing its diagnostic test to identify. Under the Agreement Cizzle Biotechnology will receive 5% of all such sums received by SGS pursuant to any AstraZeneca ("AZ") commercialisation or sub-license commercialisation of the AZ asset in inflammatory pulmonary and cardiovascular diseases, after the deduction of certain sums. Consideration for the Agreement Under the terms of the Agreement, Cizzle will pay consideration of GBP1.88 million to SGS for the Economic Interest. Of the consideration payable, GBP1.0 million (the "Initial Consideration") will be satisfied by the issue of 25,000,000 new ordinary shares in the Company (the "Consideration Shares"), at a price of 4.0 pence per Consideration Share, being a premium of 56.9 per cent. to the Company's closing mid-market price of 2.55 pence on 11 February 2022. The remaining consideration of GBP880,000 will be payable in new ordinary shares in the Company issued at 4.0 pence per share, on the sooner of receiving shareholder approval to issue the shares or the first anniversary of completion. Total Voting Rights On completion of payment of the Initial Consideration, Conduit will hold 25,000,000 ordinary shares in Cizzle representing 8.98 per cent. of the issued share capital of the Company, as enlarged by the issue of the Consideration Shares. The Company has applied for admission of the 25,000,000 Initial Consideration new Ordinary Shares to trading on the Standard Segment of the Official List and the Main Market of the London Stock Exchange ("Admission"). It is expected that Admission will become effective on or around 17 February 2022. The Company's issued ordinary share capital on Admission will consist of 278,447,788 ordinary shares of 0.1 pence each, all with voting rights. The Company holds no ordinary shares in Treasury. This figure may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company under the FCA's Disclosure Guidance and Transparency Rules. Enquiries: Cizzle Biotechnology Holdings Via IFC Advisory plc Allan Syms (Executive Chairman) Allenby Capital Limited +44(0) 20 33285656 John Depasquale Alex Brearley Novum Securities Limited +44(0) 20 7399 9400 Colin Rowbury Jon Bellis IFC Advisory Limited +44(0) 20 3934 6630 Tim Metcalfe cizzle@investor-focu Florence Chandler Notes to Editors: About Cizzle Biotechnology...... END |
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