Btg Share Discussion Threads

[fhmktg] 09/3/2016 20:01

Great news- new lease of life for CroFab?

[bookish] 09/3/2016 18:04

New Data from Largest Prospective Study on CroFab for Treatment of Copperhead Snake Envenomation BTG.L - PRN

09-MAR-2016 17:00:03


Results Demonstrate Reduced Disability for Patients Treated with CroFab®

LONDON, March 9, 2016 /PRNewswire/ -- BTG plc (LSE: BTG) announced today the
presentation of new data from the largest prospective study ever conducted in
the treatment of copperhead snake envenomation. This study builds on the
extensive body of evidence supporting the safety and efficacy of CroFab
Crotalidae Polyvalent Immune Fab (Ovine) in treating copperhead snake
envenomation. The data were shared in a keynote presentation at the Venom Week V
International Scientific Symposium (March 9-12) in Greenville, NC.
A randomized, double-blind, placebo-controlled study compared CroFab versus placebo for the treatment of copperhead snake envenomation in 74 patients (45, CroFab; 29, placebo).1 The primary study outcome was met, which was a comparison of scores on the Patient Specific Functional Scale (PSFS) - a measure of a patient's ability to do activities he or she enjoys 14 days after treatment. Patients treated early with CroFab were more fully recovered (day 14 least squares mean PSFS score difference +1.176, p=0.036). Other study measures, including limb-specific outcome tools, grip strength, physical function-related quality of life, and pain medication use, broadly supported the primary study outcome.

Principal investigator, Eric Lavonas, MD, FACEP, FACMT, of the Rocky Mountain Poison and Drug Center - Denver Health and the University of Colorado, commented: "Although highly purified antivenom has been available for 16 years, this is the first clinical trial to look at whether giving antivenom to patients whose snakebites were not life-threatening helps them recover more quickly. The results are clear. The patients who received antivenom got back to doing the activities they enjoy more quickly."

The study also sought to determine if early administration of CroFab reduced the likelihood or severity of long-term limb dysfunction in patients following envenomation.2 The results demonstrated that patients treated with CroFab following copperhead envenomation tended to have better function in their limbs and increased ability to do activities they enjoy than patients treated with placebo.3

The most common adverse events experienced by >5% of patients overall or within treatment group included headache (11.1% in the CroFab group vs 6.9% in the placebo group), pruritus (11.1% vs 3.4%), urticaria (11.1% vs 0%), nausea (8.9% vs 6.9%), dizziness (8.9% vs 3.4%), pyrexia (8.9% vs 0%), paraesthesia (6.7% vs 0%), rash (6.7% vs 0%), and pain in extremity (6.7% vs 0%).1

CroFab is the only U.S. Food and Drug Administration (FDA) approved treatment indicated for the management of patients with North American crotalid envenomation.1 Crotalids, also known as pit viper snakes, include rattlesnakes, copperheads, and cottonmouths/water moccasins.

[bargainbob] 08/3/2016 18:23

Posted by D Gaser on iii

hxxp://www.wsj.com/articles/can-varicose-veins-be-sealed-without-heat-1456164700

[bargainbob] 06/3/2016 15:56

Monday looks interesting as there was no stopping the trend on
Friday . Someone still hoovering up,the loose shares.

[fhmktg] 29/2/2016 12:08

Bring it on!

[a1ord53] 29/2/2016 11:18

Cantor Fitzgerald initiates Buy target price 800p

[bargainbob] 24/2/2016 19:45

should get 12 per cent stake by Novo by tomorrow.

[toffeeman4] 24/2/2016 18:26

Sterling weakness should have positive impact on profits.

[fhmktg] 24/2/2016 01:17

First week in April- closed period update.

[amaretto1] 23/2/2016 17:39

When is next news due ?

SP ..Weak.

[fhmktg] 23/2/2016 17:29

Just found this from a Dec '15 update to physicians in the US
Seems positive unless you are on Medicare.

Any other news items for 2016?

hxxp://apfsbilling.com/2015/12/year-end-update-on-new-technologies/

[fhmktg] 22/2/2016 16:04

By what?Crazy trading pattern with no news!

[amaretto1] 22/2/2016 15:27

its been held back.

[toffeeman4] 18/2/2016 17:40

Only see the Novo involvement as a positive. On their website they state that they work with companies as they grow. Like to think they can sort Varathena out !

[fhmktg] 18/2/2016 16:51

That sorts that then. Good to have Novo on board- at least they should understand the nature of BTG's businesses.

[a1ord53] 18/2/2016 16:42

GSC, Standard Life did from 20,090,371 to 18,595,357
and Aviva did from 19,462,890 down to 9,880,359 on 28 January (rns on Feb 01 )

[gregsc] 18/2/2016 16:31

Looks like Novo's shares came from Standard Life Investments who lowered their holding to 18M from 23M.

[fhmktg] 18/2/2016 13:57

Good whilst it lasted!Patience again until news flow takes this onwards and upwards!

[semper vigilans] 18/2/2016 12:36

The Airmiles offer expired?

[bargainbob] 18/2/2016 12:35

Novo stopped buying at 12 % or have limited price to £6 .

Who knows.

[toffeeman4] 17/2/2016 18:57

Either Novo will take BTG out, or request seat on the board !

[bargainbob] 17/2/2016 18:12

Oh btg will need to make a statement now.

[fhmktg] 17/2/2016 18:10

Another 900k in the NT or UT trading today

[a1ord53] 17/2/2016 17:41

NOVO increased yesterday holding to 11,12 %