Avacta Share Discussion Threads

[pwhite73] 30/4/2024 13:10

fieldhouse - "The share price reaction to a very detailed presentation highlights the short term'ism"

No the share price reaction correctly reflects the scepticism. Throughout the presentation she was constantly saying our data shows this and our data shows that. Once you move into clinical trials its for your peers to say "we confirm your data shows this and your data shows that" not you.

[fieldhouse] 30/4/2024 13:00

The share price reaction to a very detailed presentation highlights the short term'ism of quick buck by so called traders that could not do a proper job.!

No wonder ARM and Darktrace have gone to the US and Shell and others are considering doing so. !

Tui going to Germany in June !

A total disgrace by our financial markets .Run by spivs and sharks like HC.

Don't you just love all the sh.. sprouted !!

Back to the great outdoors and our wonderful countryside .

Great sunshine .KBO

[fieldhouse] 30/4/2024 12:35

Excellent presentation.

Dr Christina the right person to take the company forward.

[tratante] 30/4/2024 09:02

Yes, from what she says that looks like exactly what she is about to do! Christina Coughlin, Chief Executive designate of Avacta Group, added: "Having worked with Avacta now for more than two years, I have a keen appreciation for the broad potential for the pre|CISION™ platform to change the way in which we treat cancer. Avacta is delivering a truly innovative next generation of highly targeted, potent and well-tolerated cancer therapies directly to the tumour microenvironment, supported by our recent proof-of-concept data for AVA6000.

[brummy_git] 30/4/2024 08:45

Commentary wrt today's FY23 results & management reshuffle

[pwhite73] 30/4/2024 07:20

You know when a CEO has been forced out because there is not a word from them in the RNS like - "I was honoured to serve as CEO for X years..."

My interpretation is that they only mentioned AVA6000 and preCISION out of respect for the 20 years of service AS gave to the company.

It is my view they will not waste any of the recent placing money on AVA6000 or preCISION. Dr CC will look to partner a US early or mid-stage drug company with real potential for commerciality.

[fieldhouse] 30/4/2024 07:19

A good move.

A complete focus on oncology.

A huge American influence .

The poor fund raise was a clear indication that the LSE is not working

Go for gold

[goforgold1] 30/4/2024 06:53

What a scam wow .

[pwhite73] 30/4/2024 06:48

RNS 30/04/24 - "As part of this process, it has considered a wide range of candidates as a potential new CEO for the Group, reviewing both external and internal candidates. Dr. Coughlin emerged from these activities as the outstanding candidate for CEO."

It could have only been Dr Coughlin as any other external CEO would have exposed the AVA6000 lie.

RNS 30/04/24 - "We have important work in the near future to deliver on our exciting pipeline including AVA6000, pre|CISION™ and our drug conjugate pipeline."

So they have an exciting pipeline including AVA6000. What other drugs are in the pipeline other than AVA6000 and AVA3969?. My interpretation is that this is her first move to divest AVCT of AVA6000 to drugs that have the potential to work and attract other partners.

RNS 30/04/24 - "The Board also plans a broader evolution in order to meet the increased demands of being a clinical stage oncology company, alongside the need to more clearly communicate with shareholders and other key stakeholders."

My interpretation is that this includes peer reviews and medical publications as any normal oncology company with drugs that have real potential. I'm not sure what they mean by better communication with shareholders as from what I can see the communications has always been excellent and frequent.

[countbasie1] 30/4/2024 06:47

PWYou are sounding desperate now.

[pwhite73] 30/4/2024 06:38

john henry - "The scan images between Jan 2023 and Jan 2024 show clearly shrinkage in the tumours. Please explain how these tumours are shrinking if no DOX is being delivered into the Tumour."

What is not proven is a correlation between the application of AVA6000 and the shrinkage of the tumours. You need to remember these patients are already terminally ill with cancer. Such patients have natural tumour shrinkage anyway for as the body weakens tumours have less healthy cells in which to attack and grow so they themselves shrink. When the patient is dead the cancer cells are also dead.

[patio58] 30/4/2024 06:10

Great news all round! Now let's recover our value!

[john henry] 29/4/2024 19:23

Whitey during the recent presentation images were shown of a guy with Lung cancer thats been on the phase 1a trial for well over a year.
The scan images between Jan 2023 and Jan 2024 show clearly shrinkage in the tumours.

Please explain how these tumours are shrinking if no DOX is being delivered into the Tumour.

In fact if No DOX was being delivered into these Tumours they would have grown in size.

[sandcrab2] 29/4/2024 16:15

PWhite should bestir himself to see how much Dox is in the tumour. as against the plasma, according to the biopses
Detail of this is in the public domain

[amanitaangelicus] 29/4/2024 14:45

Whitey ... what are you burbling on about? MTD ... every drug has side effects ...peeps will react differently too. Remember the covid vacc warnings ...% of various known side effects pointed out. AVA6k will ,eventually, have a similar risk profile, but work needs doing here. Need efficacy dose sorting now. Please stop being childish, we are serious investors here, unlike you. No Green Eyed Monster responses - look at the share price All about set up plays. Told ya countless times. You can do it. Attachild.

[pwhite73] 29/4/2024 12:28

sandcrab2 - "they are delivering 325mg of Dox....without side effects"

If this is the case then AVA6000 works 100%.

I do not believe any DOX is being released into the tumour and at the moment neither does the wider pharmacology industry.

[sandcrab2] 29/4/2024 10:52

A long overdue put down of PWhite there

The essential point is that they are delivering 325mg of Dox to end of life patients who have exhausted other treatment, without side effects

200mg is usually a fatal. lethal dose

Some patients have been on this thing 18 months

[baldrick1] 29/4/2024 10:40

Time to take profits today.

[amanitaangelicus] 29/4/2024 06:24

Whitey you.re an idiot. Any system ie AVA6000 that delivers dox safely to targeted C cells is better than Dox alone ... what is it you dont understand? Whether it leads to life extension or maybe cures is the key point. We re hitting already very ill C victims, most whom have zero chance of survival. So, stop being so dim. Imagine if AVA6k is targeted in earlier C victims ...probs have way more success. So, please stop talking so stupidly at this early point in the proceedings. They.ve done well - so far.You.ve never understood this share. As for the LFT failure, like 99% here, you didn.t understand the significance of the conjugate antibody in the lft strip. TimeLord was gonna make his own, maybe an affimer based one, but wussed out, hence the collapse when the company couldnt respond fast enough to mutational change. Anybody will half an ounce of sense will realise you have just lied perpetually to talk the share price down. You never understood cashburn, let alone how convis work. Get to your bedroom child.

[sandcrab2] 27/4/2024 18:05

Definitely a game changer

Difficult for the board to decide when to strike a deal and for how much

[john henry] 27/4/2024 16:38

AVA6000 is almost certainly an improvement on DOX, simply by the fact that patients have been receiving far more doses of AVA6000witht far higher quantities of Dox than could ever be achieved with standalone DOX
Dox pretty much killed my mum its so toxic, Lethal.

[sandcrab2] 27/4/2024 14:51

Very rare for Big Pharma to come in at this stage

Although there are some examples

2 week testing may be a catalyst

[pwhite73] 27/4/2024 14:22

Down here nobody cares about conviboys, MM games, longs or shorts. This is why the thread is so quiet despite an 8% rise yesterday.

What investors want to see is evidence the drug actually works. People who don't know or think they know what's going on blame the falling share price on the death spiral. I've said it before and I'll say it again AVCT does not have death spiral financing and even if it did it is not the reason why the share price has dropped from 180p in February last year to 48p today.

The problem for AVCT is that the commercial pharmacology industry has seen no evidence to date that suggests AVA6000 is an improvement on Dox on its own. The data presented so far is not independent and there is no peer review in any medical journals to confirm even partial efficacy of AVA6000.

As result of this AVCT cannot source the $billions of dollars normally available for early stage cancer drugs that show promising potential. This is why it had to tap the AIM mug punter market at 50p and not 500p.

I have opined countless times before and will say so again AVA6000 is as bogus as the world beating LFT and it does please me that many of my earlier and later critics are beginning to see that I was right all along.

[amanitaangelicus] 26/4/2024 15:32

Shorts closing ...conviboys and linked mm games. Ride it baby, ride it...