Avacta Share Discussion Threads

[1347] 21/3/2024 14:03

"A number of patients remain on the three-weekly study at this time in several different cohorts."

Fine and hopefully it's helping them, great if so, but how many out of the total and what happened to the others?

As has been said before, we need hard data on efficacy and we just aren't going to get it until the end of Phase 2, which is ages away, especially with Avacta. All we get are a few titbits here and there which can't be quantified and can be interpreted however you like.

[pwhite73] 21/3/2024 11:42

Raj b - "Also, if as you suggest, there is no evidence that AVA6000 is helping then why would these patients still be taking the drug?"

It is common practice in oncology that patients who doctors have diagnosed as terminally ill try out a number of experimental drugs or drugs at very early stages. Even drugs that have failed efficacy tests at various clinical stages can be deployed on terminally ill patients only. They are simply acting as guinea pigs for the medical service. It's no different from people who donate their organs to science after they die.

A wealth of information can be gained from using early stage drugs, experimental drugs and even failed efficacy drugs on terminally ill patients. This is the information Avacta are gathering. That they are on some clinical program to find a cure for cancer is being misconstrued by some private investors.

This is why AVA6000 has been on the longest Phase 1 clinical stage in medical history.

[bonzo] 21/3/2024 11:30

We have known it works for a long time. Sadly this has no impact on the share price.

[rajraj b] 21/3/2024 11:21

Also, if as you suggest, there is no evidence that AVA6000 is helping then why would these patients still be taking the drug? If they honestly thought it was doing nothing and their life has been extended purely because of chance they would not continue. It would not matter a jot if the drug was safe if it also didn't show some efficacy. It's working man.

[rajraj b] 21/3/2024 11:07

Like I said, some will say it's purely down to chance.

[pwhite73] 21/3/2024 11:05

Raj b - "These patients must feel they have been blessed."

There is no evidence the treatment has granted these patients additional years. If there was this RNS would be a BBC1 One O'clock news item.

[amanitaangelicus] 21/3/2024 10:54

News already known to the insiders too obviously. A non event. Truth hurts.

[amanitaangelicus] 21/3/2024 10:37

Mkt just thinks ' nowt new' unfortunately. It.s just jumping through hoops. Convis your problem, hence the mkts lacklustre interest. Reset ...gulp. Could see 30p... Just saying. Mkt cap way too high still..2025 is an awfully long way off. Really hope progress can be made for the 1000.s of C sufferers out there who are desperately seeking treatment. Of course, the rich are queue jumping like crazy. NHS consultants making 1000.s privately. Disgusting state of affairs

[fieldhouse] 21/3/2024 09:33

Of course, a lot on this bb don’t give a damn !!
Such is life !!

[fieldhouse] 21/3/2024 09:31

I think it is remarkable

[rajraj b] 21/3/2024 09:18

"A number of patients remain on the three-weekly study at this time in several different cohorts."These patients must feel they have been blessed. Most would have not expected to be alive at this point. Some will say it's just down to chance but we must not forget, these patients were terminal and not given more than a few months to live.

[fieldhouse] 21/3/2024 09:03

Very encouraging RNS for those bothered to read !!
Interesting comment that the platform forms the basis for targeting cancers with far stronger drugs

[blackhorse23] 21/3/2024 08:49

Money moving to APH [LSE] , excellent profitable healthcare company

[brummy_git] 21/3/2024 08:37

More encouraging drug development news from Avacta today.

Find out all the details here.

[1347] 21/3/2024 08:32

I reckon they can spin this Phase 1 trial out so long it will get in the Guiness Book of Records. Another death spiral loan conversion coming up in a few weeks. 50 p floor looks like it may become the ceiling soon.

How's those 'transformational' Affimers going? They've been working on them for over 10 years now and, apart from the worlds best Covid19 LFT that only lasted on the market a few weeks, I'm not aware of anything else that got past pre-clinical? What's AffyXell doing?

[fieldhouse] 21/3/2024 08:29

From little acorns , great oak trees grow .
Await the Royal Marsden report with much interest .
Not long to wait !

[atmysignal] 21/3/2024 07:56

Remember, many people got shafted by the company with this ridiculous 50p raise.Can't blame them kicking at the tyres on this BB. Fact is, these people will watch this re rate and it will destroy them.

[repins1] 21/3/2024 07:53

When you look through old rns,s it's quite comical , same old same old jibber jabber

[atmysignal] 21/3/2024 07:47

Shorts now down to 1% This will re rate back to 100p this summer.Ignore the trolls.

[countbasie1] 21/3/2024 07:38

Cue Miles.

[tomavery19] 21/3/2024 07:36

Gives placees another chance to sell for somw profits

[tomavery19] 21/3/2024 07:36

Yep same old waffle.

[atmysignal] 21/3/2024 07:34

Report to the offer, now!Buckle up, here comes momentum!!