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During the recent investor discussions regarding AstraZeneca (AZN), sentiment was notably mixed, centered around the company's strategic decisions in light of ongoing political and economic challenges in the UK. One of the key developments is the company’s decision to halt its planned investment at the Speke facility, a move influenced by discussions with the current government and perceived inadequacies in the investment terms offered compared to previous proposals. This withdrawal has triggered concern among investors, reflecting a broader frustration with the government’s handling of business relations and economic policy.
Financially, the mood among investors is strained, with several participants expressing doubt about the UK's ability to adequately support industries, including pharmaceuticals. As one investor commented, “The UK has no facilities to prepare and bottle vaccines... this is madness,” highlighting frustrations about logistical capabilities that have repercussions for companies like AstraZeneca. Overall, while some investors find positives in adjusting strategies amid the political climate, the prevailing sentiment is one of concern, with discussions often veering into critiques of governmental incompetence and possible impacts on future investments and operations.
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AstraZeneca PLC has recently made significant movements in both regulatory approvals and corporate decisions. As of January 31, 2025, the company announced a total of 1,550,581,134 voting rights based on its issued share capital. Notably, AstraZeneca's Imfinzi received a positive recommendation from the European Medicines Agency for use as the first immunotherapy for limited-stage small cell lung cancer. This endorsement is based on promising Phase III trial results showcasing a 27% reduction in death risk compared to placebo, potentially expanding treatment options in a critical cancer care area.
In addition to the regulatory developments, AstraZeneca secured approval for Enhertu in the US, which is a HER2-directed therapy for patients with HER2-low or HER2-ultralow metastatic breast cancer. This approval is based on favorable outcomes from the DESTINY-Breast06 trial, marking a significant milestone in expanding treatment avenues for breast cancer patients. Conversely, the company also faced setbacks, including the cancellation of a planned £450 million investment in a vaccine manufacturing facility in the UK due to disputes over government support. These developments collectively highlight AstraZeneca's robust growth trajectory amid its ongoing challenges and strategic decisions within the biopharmaceutical sector.
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Yes, not a good appointment for big pharma. |
Closed short at just under 10000pRinse and repeat |
Maybe AZN will be reviewing their planned investment in the US following the nomination of a village idiot as the health secretary? |
'Donald Trump picks Robert Kennedy Jr to run US health department' |
This is uninvestible due to the pekinese situation.Was lucky to have placed a short at 10240 yest |
Look at BRBY this morning in comparison to AZN no wonder the UK market is uninvestable AZM beat expectations and upgraded the share price fell on result day. |
#POLX Polarean Imaging 1.6p about to break out above 2p soon. Mcap only $20mil. I see it as a steal for the FDA approved Xenon MRI. No company debt, masssive growth potential in the worlds biggest health market the United States where it's already in 21 clinical settings, best in class next generation MRI. Revenues rising up 3000% to $3mil for 2024 and doubling again next to $6mil in 2025. 1.6p and gap to fill to 3.2p, so 100% rise just to fill the technical gap. ATH 100p. My target is recovery to 25p. |
AstraZeneca backs US and China - but new UK vaccine factory hangs in the balance |
AstraZeneca’s £450m UK investment under review in state aid stand-off |
double post |
Reading the results problems in China seems very low key as below from results looks unlikely that it will cause any lasting problems to AZN, and if it does its only 5% of company profits from which it may lose a few percent not all I would suggest. |
Agree Monty that China is the big hurdle for any positive share price movement regardless of the results and progress they make. |
These are still looking very weak, I suppose investors hate uncertainty, with China. |
AstraZeneca PLC AstraZeneca invests $3.5 billion in US |
They have changed the plans for a cancer drug to target fewer patients which is something the analysts pay a lot of attention to.But I believe it's bigger opportunities are ahead.I have seen in the past that the shares can often be directionless until the US wakes up |
Keep the Faith like Bishop Welby !! |
Its a disappointingly muted response to excellent figures but as Ijat suggests, its probably as much to do with a general disenchantment with UK equities (and a Labour government that seems confused as to how to promote economic growth)as concern re the China situation.Long term buy but there's a lot more immediate excitement and opportunity on Wall Street PS....i presume that Starmer and Reeves must be disappointed that billions is earmarked for expansion in the USA. |
Shorters were probably prepared to sink it deeper but the results disappointed them. |
While I think the China issues will turn out to be manageable, there is some doublespeak going on…..how many China CEOs are detained without the Company being under investigation… |
Probably just the UK market at a guess an unbelievable reaction to excellent results. |
Could it be the currency effect that cancelled the positives ? |
Looking very good would never have bought at £130 but at £98 I had to, it seemed far to low for a problem affecting less than 5% of profit. |
Upgrade to full year guidance on the back of some great numbers.Great figures across the board will hopefully ease the China situation and we should have a great day with the share price.Fingers crossed. |
Shore Capital has maintained its ‘buy’ rating on the stock, seeing it as undervalued despite the growing uncertainty. “Q3 results next week could help to allay some of these concerns,” analysts said. |
AstraZeneca has explaining to do after £50 billion value wipe out |
Type | Ordinary Share |
Share ISIN | GB0009895292 |
Sector | Pharmaceutical Preparations |
Bid Price | 11,314.00 |
Offer Price | 11,320.00 |
Open | |
Shares Traded | 0.00 |
Last Trade | 00:00:00 |
Low - High | - |
Turnover | 45.81B |
Profit | 5.96B |
EPS - Basic | 3.8406 |
PE Ratio | 29.47 |
Market Cap | 174.84B |
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