Share Name Share Symbol Market Type Share ISIN Share Description
AstraZeneca LSE:AZN London Ordinary Share GB0009895292 ORD SHS $0.25
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -50.00p -0.92% 5,398.00p 5,403.00p 5,405.00p 5,455.00p 5,395.00p 5,419.00p 3,589,445 16:35:29
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Pharmaceuticals & Biotechnology 16,632.7 1,648.8 175.5 30.2 68,371.80

AstraZeneca Share Discussion Threads

Showing 7451 to 7471 of 7475 messages
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Study findings show statistically significant overall survival with clinically meaningful improvements in non-small cell lung cancer patients receiving AstraZeneca’s IMFINZI compared to placebo
The US listing looks like it's going to end up flat on the day
well those results didn't do the comparison chart much good, more catching up to do now! but I like the growth in China and pipeline here vs GSK
AstraZeneca PLC18 May 2018 07:00Q1 2018 ResultsEncouraging launches and the performance of newer medicines underpin reiterated guidanceAs expected, the Product Sales performance benefitted from strong launches and the continued growth of newer medicines and China, offset by the erosion of Crestor sales. Progress was made on overall cost discipline, while the level of Externalisation Revenue, divestment timing and investment in launches impacted the overall results. Patients continued to benefit from the progress of the pipeline and AstraZeneca's plans remain on track, with the Company continuing to anticipate Product Sales growth this year, weighted to the second half.
from the Q1 results: A China sales increase of 31% (22% at CER) to $1,025m. For the first time, quarterly sales of more than $1bn were achieved, underpinned by the launch of Tagrisso.
Results tomorrow
still needs to catch up a bit with GSK since I showed an interest! (and no-one mention dividends!) AZN has the most promising pipeline however imho
I would look into HEMO (aim listed) flying as i write this!!!! Nai.dyor.imho etc
Price is very volatile,but seems to keep wanting to push higher.
Broker upgrade maybe?
Weak pound perhaps?
Anyone know why the big increase today?
Department for Environment, Food and Rural AffairsAnimal & Plant Health Agency Veterinary & Science Policy Advice Team - International Disease Monitoring Situation Assessment ........ Update on Chronic Wasting Disease in Europe .......... 25 April 2018 Disease report In March 2016, the cervid Transmissible Spongiform Encephalopathy (TSE), or Chronic Wasting Disease (CWD) was reported in reindeer in Europe for the first time with a case in Norway. The source of infection and time and route of incursion is not known. This is an update on the surveillance results in Norway and also includes an assessment of the first case of an atypical TSE/CWD case reported in Finland. There have been no detections of CWD in Europe outside Norway and Finland to date and no cases of cervid TSEs in the UK. This report is to inform readers of the ongoing likelihood of more CWD cases in Europe and also the risks to the UK. Attention is also drawn to a forthcoming paper documenting detection of prion disease in camels in Algeria. This demonstrates the need for ongoing awareness of TSEs in other livestock species in different parts of the world. buywell3 says As I have said before .... the Whale in the room continues to pass through , unseen by 99% of all those in it hTTps:// In the USA 25 states now report CWD in deer moose and elk ... it is spreading OUT of control
No, no cure exists for Prion Disease ... and there are several types affecting several different animals , fatal in all cases. Thus far only cattle have been linked to human transmission via BSE and CJD and vCJD again fatal in all cases. However since that outbreak , in the USA deer, elk and moose have developed CWD which is a TSE like BSE , this has the potential to affect humans no tests done but Canada and the USA are testing shot deer and in 25 USA states tests are coming in positive for CWD ... it is spreading. Voles and squirrels are also affected by prion diseases. CWD is a prion disease , also present in Canada , Norway , South Korea and last month in Finland. Now another animal species is affected a new development .... A neurodegenerative disease discovered on camels in Ouargla 15 April 2018 A scientific study carried out by the Italian Higher Institute of Health (Istituto Superiore di Sanità, ISS) in collaboration with the universities of Tlemcen and Ouargla has led to the discovery of a new prion disease on camels of the region of Ouargla, reports the Outbreak News Today website. Prion diseases (pathogenic protein) are life-threatening neurodegenerative diseases that can affect animals and humans, such as Creutzfeldt-Jakob disease or Bovine Spongiform Encephalopathy (BSE), the common name of which is disease of the liver. Mad Cow). The neurological symptoms seen in dromedaries precisely recalled those of mad cow disease, leaving Algerian researchers suspect that it would be a prion disease. Suspicions were confirmed by laboratory tests carried out by researchers at the Italian Health Institute. Symptoms suggestive of prion disease appeared in 3.1% of dromedaries brought to the slaughterhouse of Ouargla during the 2015-2016 period. The new disease has been dubbed "Camel Prion Disease", which can be translated into "camel prion disease". The relatively high frequency of the disease and the involvement of the lympho-reticular system suggest that it is a communicable disease within the species and widespread in the region, says the study. "The discovery of a new prion disease in an animal species with economic and food value in large areas of the planet raises important issues of public health and food security," said Gabriele Vaccari, head of ISS. "Camel rearing is widespread throughout North and Central Africa, as well as in the Middle East, Asia and Australia, and is an important element in the economy of many populations. In many areas, camels are used for the production of milk and meat for human consumption, "said the researcher. The results of the investigation so far suggest that the prion disease affecting the camel is different from BSE, with the cow being the only animal to have so far shown that its disease could be transmitted to humans with more than 200 deaths in different parts of the world, says the study. Nevertheless, the risk to humans is currently unknown, and a thorough investigation is needed to clarify its zoonotic potential, say the researchers.
Buywell does AstraZeneca have a cure for this malady?
Sterling going back to pre brexit level against the dollar probably hasn't helped either
Astras recent weakness likely as a result of Woodford going from 9% to 1 to help meet redemptions and of course invest inUk focused stocks , assuming you believe the latter. Redemptions more significant I suspect .
Surprisingly quiet board
buywell3 We have ALREADY had prion issues in this country! LOL What do you thing Mad Cow Disease was? You probably already have the prions in your brain. We all probably do. The illness was derived from sheep, which have carried this illness since time began. So, can you please stop posting on the AZN thread and create your own. Thanks.
Many BIG Pharmas have spent $ Billions trying to find a cure for Alzheimer's Prion disease is the whale passing through the room But it is soon to get recognised for what it is and the threats that it presents Deadly ... no cure UCLA researchers determine atomic structure of defective prions January 29, 2018 UCLA researchers have determined the atomic structure of part of a protein that causes certain neurodegenerative diseases. In a study published earlier in January, researchers in the lab of Jose Rodriguez, assistant professor of chemistry and biochemistry, determined the structure of a segment of prion, a protein that causes diseases such as mad cow disease, when it is defective. Visualizing the prion allows other researchers to understand the basis behind prion diseases and develop therapies toward preventing and treating them. Prions, which are found mainly in the brain, may randomly become defective and convert normal prions into additional defective prions, spreading the disease throughout the brain and resulting in death, according to the Centers for Disease Control. Individuals who come into contact with the flesh or fluids of animals with defective prions can contract them, spreading the disease. Prion diseases are particularly dangerous because defective prions aggregate into stable clumps of protein that the body cannot easily break down, Rodriguez said. “You can boil (a prion aggregate), dip it in acid, treat it (with harsh chemicals), and it still won’t lose its shape or break apart,” he said. Rodriguez said his lab decided to determine the structure of the defective prion in order to understand its extreme stability. Calina Glynn, a graduate student in Rodriguez’ lab, said they studied a segment of the prion of a small rodent called the bank vole. This segment behaved like a defective prion, so it served as a good model for studying prion diseases, Rodriguez said. While most animals usually do not contract prions from other species, the bank vole easily contracts defective prions from other animals, Glynn said. Marcus Gallagher-Jones, a postdoctoral researcher in Rodriguez’s lab, said studying the bank vole prion may explain why bank voles are so susceptible to prion diseases and inform further research on how defective prions spread. The researchers used a technique called MicroED to determine the protein’s structure, Glynn said. MicroED allowed the researchers to see fine details in the protein structure that would otherwise be invisible with traditional techniques like X-ray crystallography, she said. Gallagher-Jones said that using MicroED, the researchers could see the position of hydrogen atoms in the protein, a feat not normally possible with X-ray crystallography. Seeing the hydrogen atoms helped the researchers realize the hydrogen atoms form a network that helps glue prions together into an aggregate. “We’re very interested in seeing how the network of hydrogen bonding plays a role in the prion’s stability,” he said. Rodriguez said his lab’s work highlighted the advantages of MicroED and that a high resolution structure of the aggregated prion can help other researchers develop approaches to treating prion diseases. “MicroED (allowed us to determine) structures of proteins that have been challenging by traditional methods,” he said. “We’re now starting to get high-resolution structures of prions in their aggregated state. It’s a goal that was out of reach for a while.”
Good news here this morning
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