Tiziana Life Sciences Share Discussion Threads

[marcus80] 29/4/2023 09:16

??? what do you mean Jpuff?? you just can't understand logical opinion (facts). Tiziana is a lifestyle company... just like GC's previously company that got delisted.
GC will do a massive fundraise this year end leave you all behind with zero return!
Enjoy your weekend

[jpuff] 27/4/2023 19:04

As an aside I feel the tone of certain posters to be terse and unnecessarily rude, provocative and profane. Ladies frequent these boards too, so can I respectfully ask those concerned to conduct themselves with this in mind. Differences in opinion will always exist but please keep it civil.

[jpuff] 27/4/2023 17:56

Well as Sten said it's all a gamble. You guys go short then and buy me a pint if you win and I'll stay long and reciprocate. It's a market after all with constant buyers and sellers so we have differing opinions obviously ?

[marcus80] 27/4/2023 17:16

delisted end of year imo

[lean5gb] 27/4/2023 16:19

You were told.

[jpuff] 27/4/2023 13:09

Tiziana Life Sciences Announces Findings from Intranasal Anti-CD3 mAb Treatment in Intracerebral Hemorrhage at the Annual American Academy of Neurology ConferenceApril 27, 2023 at 7:00 AM EDTThere are no effective treatments for intracerebral hemorrhage (ICH), which has a 30% to 40% mortality rateIntranasal anti-CD3 mAb treatment showed a reduction in Intracerebral Hemorrhage injury severityIntranasal foralumab could represent a novel therapeutic approach for treating ICH and potentially other types of acute brain injuryNEW YORK, April 27, 2023 (GLOBE NEWSWIRE) -- Tiziana Life Sciences Ltd. (Nasdaq: TLSA) ("Tiziana" or the "Company"), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced broad-based findings on the utility of nasal anti-CD3 mAb in the treatment of intracerebral hemorrhage (ICH). The data using a mouse model of collagenase-induced ICH was presented at the Annual American Academy of Neurology conference. The full presentation can be viewed at https://www.aan.com/MSA/Public/Events/AbstractDetails/52974 until May 14, 2023.Howard L. Weiner, M.D., Chairman of Tiziana's Scientific Advisory Board and Co-Director of the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital, a founding member of Mass General Brigham Healthcare System, stated, "Intracerebral hemorrhages are the deadliest form of acute stroke with early mortality ranging from 30% to 40%. It has been well demonstrated that microglial activation and edema play a critical role in the morbidity and mortality of this devastating event."Saef Izzy, M.D., MBCHB., Neurocritical Care faculty at Brigham and Women's Hospital and Assistant Professor of Neurology at Harvard Medical School and presenter of the study at AAN, commented, "Currently, there are no effective interventions for ICH. Our research studied the effect of an intranasal anti-CD3 antibody in a mouse model of induced ICH. I believe that intranasal anti-CD3 represents a novel therapeutic approach for treating ICH as well as potentially other types of acute brain injury."Specifically, the study demonstrated that intranasal anti-CD3 antibody:1Reduced ICH injury severityImproved motor coordination recoveryImproved memory retention and functional recoveryAccelerated hematoma resolution at 7 days after ICHReduced neuronal cell death at 7 days after ICHReduced BBB leakage at 3 days after ICHReduced microgliosis at 7 days after ICHReduced astrocytosis at 7 days after ICHIncreased CD4+FoxP3+ and FoxP3+ IL10+ dependent Tregs at the site of hematoma at 7 days after ICHIncreased anti-inflammatory and reduced pro-inflammatory cytokines at the site of hematoma at 7 days after ICHUpregulated microglial phagocytic transcriptomic profile at 7 days after ICH Modulated microglial and astrocyte transcriptomic inflammatory profile after ICH"The comprehensive and consistent findings of Dr. Izzy's research strongly supports the promising role of intranasal foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), and its potential for broad applications in neuroinflammation, including the treatment of acute ICH," said Gabriele Cerrone, Executive Chairman, Founder, and interim Chief Executive Officer of Tiziana. "These exciting findings may allow Tiziana to explore additional intranasal foralumab neuroinflammatory indications to help patients with unmet needs and create further shareholder value".

[lean5gb] 26/4/2023 22:52

Your last comment on the bark thread jp?Exactly my sentiments here. Get real, and dont be a hypocrite.

[jpuff] 26/4/2023 22:05

Second thoughts a shorter

[jpuff] 26/4/2023 20:01

Bye then, you won't be missed

[jpuff] 26/4/2023 14:04

I find it incredible how some folk who have no positive interest or position in the company spend so much of their time following it so closely. There's plenty of other stocks out there to choose from that don't carry baggage from the past as they say.

[elias2] 26/4/2023 13:12

anyone know what price this stock was floated at on the nasdac? did the lse closing price transfer directly over to usd share-for-share?

[lean5gb] 25/4/2023 22:30

.... And so it goes that the long covid and diabetes route are also 'can kickers'.

[lean5gb] 25/4/2023 22:25

C'mon on sten. What are the possibilities of the product coming to fruition, concerning alzheimers, when the idea originally stemmed from rgts colostrinin? The bods are just kicking the can, and making a good living from it. Biggest scam out, and that's the history summed up perfectly.

[stenick] 25/4/2023 18:51

I hear what your saying lean, we all have to make our own decisions and the first decision to invest in shares is a personal and precarious thing and one we may regret or applaud, it’s a personal decision and there are plenty out there who will bad mouth it, but hay it’s gambling!

[lean5gb] 25/4/2023 08:05

... Blocked.

[lean5gb] 23/4/2023 18:05

I have let it go Sten. I just like to inform the other peeps to be very diligent with this company and its history. To be honest, the majority of aim company bods are also bent and self indulgent.. . . Nuff said.

[stenick] 23/4/2023 17:35

No beef then lean.
lean5gb13 Apr '23 - 08:19 - 17726 of 17735

[stenick] 23/4/2023 16:47

Lean don’t get all sour and bitter about Percy, after all in around about way he is the reason I am here, and you,
I reckon this a totally different ball game although being in the same game.
My old mum used to tell me if something is bothering me ‘Let it pass through you’
New ball game 🚀🚀🚀💥7965;🏝

[jpuff] 20/4/2023 17:41

April 20, 2023 7:00 AM EDTTiziana Life Sciences to File Alzheimer's IND for Intranasal Foralumab in Q2 2023

[jpuff] 18/4/2023 19:48

April 18, 2023 7:00 AM EDTTiziana Life Sciences Initiates Program to Develop Intranasal Foralumab in Type 1 Diabetes

[jpuff] 17/4/2023 18:07

And that's just from dropping the soap in the shower Sten ;)

[stenick] 15/4/2023 20:24

Lol..😂