Sdi Share Discussion Threads

[ronwilkes123] 26/3/2019 12:40

Why hit so much today

[ronwilkes123] 26/3/2019 11:27

Where's the key point on the chart buywell 43p ? If it goes under this is it a chart failure ?

[ronwilkes123] 25/3/2019 13:01

Apologies Hastings I meant finals

[ronwilkes123] 25/3/2019 11:27

Interims only four weeks away

[buywell3] 25/3/2019 11:23

Depends if our Institutional sellers Octopus and Miton are still sellers

Why they would be sellers beats me with this chart set up

The 50ma has gone through the 100ma and is now just pushing through the 200ma

Can't get any better really when put together with recent news flow on good acquisitions made

But who knows they might have made the decision to exit completely ?

Remembering they both did most of their selling at 34.5p to 35.5p area last time

[ronwilkes123] 25/3/2019 11:15

I'm not sure buywell - the twitterati announcing sales late last week may mean we drop back in the short term

[buywell3] 25/3/2019 11:00

Of course he is still holding

SDI could get bought out at any time

We don't know who has bought around 20% of their stock in the last 3 months

This is one of those companies that you have to be in it to win it

News could come any day

[ronwilkes123] 22/3/2019 20:26

Still holding buywell ? You've gone quiet

[ronwilkes123] 21/3/2019 08:59

I expect maybe 5-10% higher than today

[tomv33] 21/3/2019 08:52

What do you expect the price to go up to by the end of this year?

[ronwilkes123] 21/3/2019 08:44

How big do you think sdi can get ?£1.00 within 3 years ?

[buywell2] 21/3/2019 08:35

Before this coming Xmas IMO


Now here is a very interesting chart to look at , AGM update came out today and it is very good IMO


Another thing you need to learn about with Charts is Cycles ie repeating chart shapes in similar time frames , they are here as in SDI chart I have posted previously

[ronwilkes123] 20/3/2019 20:01

60p buywell In what timeframe

[buywell2] 20/3/2019 18:51

New Product Upgrade/Development


... Ames software for ProtoCOL 3 now features Mutagenicity Ratio Functionality ...

March 7th, 2019

Cambridge, UK: Synbiosis, a long-established, expert manufacturer of automated microbiological systems, today introduced its next generation Ames software module featuring a time-saving Ames mutagenicity ratio calculation function.

The new software designed for integrated use with the ProtoCOL 3 colony counter, facilitates rapid production of accurate, consistent, count and ratio data from Ames test plates and is ideal for use in regulated toxicology testing laboratories.

The new Ames software enables ProtoCOL 3 to quickly count Salmonella typhimurium or E.coli colonies cultured on, for example, Vogel Bonner medium before and after exposure to potentially toxic or non-toxic control compounds.

The software can then automatically compare the different colony counts to generate an Ames mutagenicity ratio, providing a quick guide to the mutagenic potential of a test chemical.
This saves microbiologists time and effort with transferring count data to statistical software or manually calculating the ratio. It means ratio results are objective as they are not dependent on the scientist performing the tasks.

As well as numerical data, the software also produces full colour images of Ames test plates which can be stored in a secure SQL database for reference and another count, if required.
Count and ratio data can be automatically downloaded to a spreadsheet (Excel/ OpenOffice) or LIMS, thus eliminating data transfer errors, to generate reproducible, traceable results, which are consistent from one microbiologist to another.

Featuring user access levels and a full audit trail with user login and logout records, the new Ames software is GLP compliant and can be used in a 21 CFR Part 11 environment. The archived results are suitable for generating high-quality reports for audit by regulatory authorities, making the new Ames software appropriate for use in pharmaceutical toxicology testing and other regulated microbiology laboratories.

For more information about the innovative new Ames software for the ProtoCOL 3, please click the link: hxxps://www.synbiosis.com/product/ames-software/

Users with Ames software licences for ProtoCOL 3 can download the upgrade free of charge from this link: hxxps://www.synbiosis.com/support/software-downloads/

“Manually calculating the Ames mutagenicity ratio by comparing different sets of colony counts is a common approach for determining if a compound is mutagenic, but it is time consuming and can be prone to human error,” says Kate George, Sales and Technical Director at Synbiosis.

“Our new module with its ratio calculation function is a time-saving solution to this problem and makes the ProtoCOL 3 and integrated Ames software an intelligent choice for any toxicology testing laboratory.”


buywell says:

The Ames test is a widely used and recognized test for Mutagenicity


This is a very clever use of technology by Synbiosis that opens IMO wider applications to pre-clinical testing of new drug compounds in the Pharma Industry.
Genotoxicity forms part of the very important and growth area within ADMET the T being Toxicology ... the main reason why new drug compounds don't make it to clinical trials and the main reason why approved FDA drugs get withdrawn ... costing $Billions.

Genotoxicity

Genotoxic chemicals exert their adverse effect through interaction with genetic material (DNA) of cells.
Genotoxicity tests are designed to detect drugs which can induce genetic damage directly or indirectly by various mechanisms of action. Compounds identified as genotoxic in these tests have the potential to be human carcinogens and/or mutagens, and ultimately may induce cancer and/or heritable defects.

Genotoxicity testing of new chemical entities is an integral part of the drug development process and it is a regulatory requirement prior to the approval of new drugs by the FDA and other authorities.

Hence by identifying genotoxicity at as early a stage as possible in a drug discovery program rather than during regulatory assessment, the likelihood of late stage failures is reduced and hence time and costs avoided.


Synbiosis could add other Genotoxicity test protocols if this proves a success

I can't see how it can't do any other

This is IMO a very important development as it levers the Synbiosis ProtoCOL 3 colony counter into bigger areas of sales V competitors who offer other Genotoxicity tests such as:

In vitro Comet test
pH3 and pH2AX genotoxicity assay
micronucleus test (Flow Cytometry using TK6 cells)
γH2AX double strand DNA damage

[buywell2] 20/3/2019 18:20

New Product upgrade/development

...... New eco-friendly, EPI UV HI-LED lights for Syngene G:BOX imagers .....

March 5th, 2019

Syngene, a world-leading manufacturer of image analysis solutions, today introduced a new Epi UV HI-LED lighting option for its popular G:BOX Chemi and G:BOX mini multi-application gel and blot imaging systems.

These environmentally friendly lights allow faster workflow and more accurate results when imaging a diverse range of fluorescently labelled proteins on gels and blots.

With an excitation wavelength of 365nm, the Epi UV HI-LED lights transform G:BOX Chemi and G:BOX mini systems into higher-performance imagers capable of detecting SYPRO® Ruby labelled proteins, colonies and proteins labelled with wtGFP, as well as fluorescent proteins on TLC plates.

Since the new lighting is around 200 times more intense than standard LEDs, exposure times are shorter, which means G:BOX systems are excellent for rapidly imaging complex multiplex fluorescence blots, 1D and 2D gel applications.

Featuring up to 100,000 hours’ service life, the eco-friendly, Epi UV HI-LED lighting is automatically controlled by GeneSys software via an intuitive, icon-driven set up. This powerful lighting and G:BOX combo, with its real-optical imaging, provides unrivalled resolution and sensitivity, allowing scientists to accurately visualise close bands; precisely detect DNA and proteins down to the femtogram level, and enjoy great publication-quality images every time.

Please click the link now, to find out where to get the new Epi UV HI-LED lighting:

“Many scientists want to use sensitive dyes like SYPRO® Ruby to detect low-expression proteins but often do not have access to systems that provide Epi UV illumination” states Dr Martin Biggs, Sales Manager at Syngene.

“Fitting our new Epi UV HI-LED lighting to a G:BOX Chemi or mini enables these systems to become imaging powerhouses and offers an ideal solution for budget-conscious labs that need to quickly and accurately quantify proteins on gels, blots and even TLC plates.”

[buywell2] 20/3/2019 14:25

Well I am going to do a big favor and send you to the Chart School where I learnt

It will take you several weeks to go through this learning process about charts and TA

But it will make you a better investor




Let's say for now that after the next set of record results come in , which I expect , that IMO SDI should be 60p


This says that if you go to school and learn to read charts

[ronwilkes123] 20/3/2019 11:36

Genuine interest - I've sold my hur yesterday and moved on I'm here at 47p - I'm after your charting nous

[buywell2] 20/3/2019 10:25

I see 90% of your posts are about HUR ron

Is it a genuine interest in SDI you have or my charting nous you wish to test ?

[ronwilkes123] 20/3/2019 09:13

What's your year target share price here buywell ?

[buywell2] 20/3/2019 05:11

.......... ATC to Exhibit at ArabLab 2019 with Meslo ..........

25 February 2019


ATC is exhibiting alongside Meslo, our representatives in the Middle East and Africa, at the popular ArabLab show in Dubai, March 2019.

After the success of our first year of exhibiting at ArabLab in 2018, we are pleased to return to this year’s specialist event.

ATC will be amongst over 1,000 companies meeting with over 10,000 international visitors who are hoping to find new suppliers, experience the most up to date technological innovation and networking with contacts from all over 100 countries around the world. ArabLab is a must see show for anyone who works within the laboratory, scientific or the analytical field.

New for the show is the Mini chiller.

We are delighted to demonstrate our latest chiller development and innovation in the form of the Mini, designed for environments where space is at a premium and ideal for benchtop laboratory applications.

With 500W of power, the compact unit is the smallest and most energy efficient chiller ATC have produced, particularly useful in biomedical laboratories. Combining a sophisticated touchscreen controller and variable speed compressor with a universal power supply.

The Mini provides quiet and effective cooling performance, up to 500W.

Working in conjunction with Meslo helps ATC to broaden our offering to more markets and ArabLab is in great proximity to some of the fastest growing in the world. We are very excited to meet new contacts and to develop business relationships in the region, we anticipate this will lead to growth for both Meslo and ATC.

The show is open 12th – 14th March 2019, come and visit us alongside Meslo on stand 130-136.


buywell says: note new mini chiller gets a mention , the whole new product range will be on show which is now BIG ... see the products link on the Applied Thermal website in my previous post.

[buywell2] 20/3/2019 00:16

We need a new thread ... this one is too out of date ... lots of acquisitions since 2014 ... the company is now totally different/transformed from where it was

What we need is for somebody to take on the job

[ronwilkes123] 19/3/2019 20:43

Buywell happy for a new thread - if someone wants to do one

[pugugly] 19/3/2019 20:11

buywell2 - He looks to be no longer an active member of ADVFN - His last post was

SDI - Global & Niche imaging portfolio for scientific & medical users - Post 150

SDI Scientific D.

Author: Nick2008 Posted on: 15 May 2014 11:29

This raises another point about dormancy of ADVFN non premium members? Or do they live on for ever in cyberspace?

[buywell2] 19/3/2019 19:33

Nick2008

The thread creator has not posted since 2014

This thread is not fit for purpose and does the company no credit now