Reneuron Share Discussion Threads

[supernumerary] 24/2/2020 19:29

Better to pop down to Kwik Fit and swap out the whole thing for the new improved model :)


The horror! The horror!

[small crow] 24/2/2020 17:48

Yes, brain implants needed for presbyopia. One day.

[martinfrench] 24/2/2020 16:23

personally think these results are excellent, all things considered

[supernumerary] 24/2/2020 15:06

That's clever!

Unfortunately none of these solutions really address the problem of presbyopia - what's needed is a way of making the lens more flexible, not just more or less powerful. I imagine it will come (or perhaps it's here and I haven't heard of it yet?).

[algernon2] 24/2/2020 14:56

Also consider "Light Adjustable Lenses" SC as they can be put into the eye and altered/adjusted when actually inside the eye by shining various frequency light at them and then locking them into shape when the optimum configuration is achieved.

[small crow] 24/2/2020 14:29

PS Yes, that's one reason I've always avoided laser .... eyes do change and you cannot undue. Better option, which I might consider for one of my eyes (the more astigmatic) is an intraocular lens. You can always take it out and stuff in another.... for a price.

[small crow] 24/2/2020 14:27

Agreed. I think the only "downside" is that things may be as good as they get after 12 months, rather than continuing to improve. However, if your sight is going to probably don't want to wait 3 years for improvement and, also positive, this is just the first draft of a therapeutic. Things can only get better, as Mr Blair used to say.

[supernumerary] 24/2/2020 12:32

sc - I've had the same transition - started short-sighted (very!), had it fixed by laser (giving excellent all-round vision), and now long-sighted and forever fiddling with pairs of reading glasses - infuriating!

I also think the news is reassuring. The first requirement is always that things shouldn't get worse, and I think we can now safely abandon that possibility. So we're only looking at degrees of success, which is a nice position to be in.

I'm also pleased they're now showing improvement of treated eye over untreated, rather than just improvement over baseline, as that eliminates some of the baseline movement which might occur with age-related changes, or variations in general health.

[small crow] 24/2/2020 11:06

Yes, thanks super, I still think that's what might be happening. The most common cause of people wearing glasses for years and then not needing them is that most of us tend to become more 'long-sighted' as we age, so all of those who needed correction for short-sight (ie loads of us) tend to need them less as we get older. I'm typical - my eyes have shifted about +2 diopter units over the last 40 years - I used to need specs for driving but not now.

Anyway, The data looks a bit better with increasing samples but I would guess the market is still worried about a potential decline in acuity after 9 months and will want to see a longer time series. FWIW, my opinion is that the better measurement to use, as a real indicator of the improvement as perceived by the patient, is the sum of the improvement in both eyes. On that measure the improvement in what they see (ie with both) begins at around 12 units, increases to 24 units at 9 months, and declines far less between 9 and 12 months. Either way, I suspect the market is reassured (ie no catastrophe) but will need to see more before hands go in pockets.

[supernumerary] 24/2/2020 10:17

cotton - I think this is a more likely explanation:

small crow26 Oct '19 - 10:32 - 7427 of 7560 0 1 1
Nobby, thanks for that. I'm not that surprised that the untreated eye seems to improve as you have to factor in the computational stuff between the retina and the "perception" to get the final result. It could be the case that better input to the visual centres/optic tectum is causing changes that benefit the signal processing in both eyes. It's like a mild case of the groundbreaking Colin Blakemore experiment where he demonstrated that, if you raise animals from birth in an environment where they never see a horizontal line, then transfer them to a regular environment, they can't perceive horizontal lines. In this case the signal processing is not used to processing a "sharp" image but, once presented with one, gets better at doing it. It's an idea and, more importantly, good news for both eyes.

[dickbush] 24/2/2020 09:43

It is a really, really bad day for the market. Not declining with it is a major achievement.

[zooman] 24/2/2020 08:52

ID, Rene is fickle, news comes out and sometimes it takes it time to react. Rather have positive news than the other but just wish we could get that good one in order to get things moving. Zoo

[investordave] 24/2/2020 08:19

Oh well. Looks like the market doesn't think much of that update either.

[cottonpickers] 24/2/2020 08:13

Wow. Very interesting. I Did not know that. Tx

[peteark] 24/2/2020 08:10

As less strain is placed on the unaffected eye it will strengthen. Some people that wear glasses for years can end up not needing them as less strain is placed on the eyes

[cottonpickers] 24/2/2020 07:30

I'm curious how the non medicated eye also shows some (smaller) progress over time. I would expect it to deteriorate over a 12m period but I'd does not. Is that placebo effect? I would not expect placebo would allow you to read more lines. Thoughts?

[ayl30] 24/2/2020 07:21

Positive news, let's see what the market make of it

[bonzo] 24/2/2020 07:08

The news we have all been waiting for!

[dplewis1] 23/2/2020 07:57

Do not click that link from petershares1- same spam link as yesterday. There is no Times article..

[peteark] 22/2/2020 22:06

hxxps://youtu.be/i2xK3Ls0jFU

[dickbush] 22/2/2020 12:07

I was thinking about a takeover bid by someone in the industry. A third of the company has been available for weeks, if not months. Even now, the very recent buyer of 16% would, I'm sure, be very happy to take a fast profit.

[dickbush] 19/2/2020 17:31

I have to wonder why-if RENE has such great prospects-no one seems to want to buy it on the cheap.