Reneuron Share Discussion Threads

[small crow] 23/9/2016 07:58

freddie

Interesting. Thanks for highlighting.

[fredd1eboy] 23/9/2016 07:45

Bit of positive info c/o mol iii site...

as we know recruitment now closed - clinical trial site updated 160916

hxxp://clinicaltrials.gov/ct2/show/NCT02117635?term=reneuron&rank=2

looks like 23 actually recruited from original 21

Enrollment: 23
Study Start Date: June 2014
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: July 2017 (Final data collection date for primary outcome measure)

and a reminder what the original trial criterion was - this has subsequently been deleted in latest update above

If 2 or more patients satisfy the primary response criterion 6 months after treatment with CTX DP in 1st stage, the study will progress to the 2nd stage and enrolment will be increased to 41 patients. If after 21 patients, fewer than 2 patients satisfy the primary response 6 months after CTX DP treatment, no further patients will be enrolled and the trial will be concluded.

obviously we achieved more than two and also determined that results to date (we await update before calendar year end) merited the end of further recruitment up to 41 and preparation of application for a pivotal trial both here and US.

Recruitment commenced as we know in August 2014.

excerpt recent trading update

We are pleased to report today that all patients have been treated in the PISCES II Phase II clinical trial of our CTX cell therapy candidate for patients with motor disability as a result of ischaemic stroke. The three-month follow-up data from this study will be available, as planned, in December of this year. Subject to the results of the Phase II study, and as previously announced, we expect to file an application in the first quarter of 2017 to commence a
randomised, controlled Phase II/III clinical trial with CTX in patients with motor disability post
-stroke.

so ahead of original estimated completion date of dec 17 by over a year - the company had previously intimated that the trial may be terminated early subject to initial results

so what do we expect before calendar year end...........?

well i know what i expect

[fredd1eboy] 18/9/2016 17:51

Wednesday 21st Septenber

Reminder.....

The Inaugural UK Regenerative Medicine Conference
20-21 September 2016

Royal Institute of British Architects, 66 Portland Place, London, W1B 1AD


14:50 Dr John Sinden
Reneuron
Short Presentation: Chronic disability after stroke: Can neural stem cells provide a cure?

[fredd1eboy] 06/9/2016 17:57

I have just visited Reneuron's web site and reminded myself of Micheal Hunts video presentation on the investment case for reneuron.
I am also pleased that Reneuron business is progressing well and to plan
I am also pleased the share price has held today and hope that it will now attract the type of investor Micheal Hunt was hoping for several months ago and recover over time as its being a long time coming.
As a small shareholder with a significant investment at well over 5m shares, I get very depressed when I review my paper loss.
I have taken damage limitation measure by consistently topping up over recent months/years.
When I see the amount of share options being awarded to directors I feel even more depressed.
We all hope for a recovery in months to come and as such I am not impressed with individual directors reluctance to have a good splash out. I note that Olav bought some stock aroiund the time Micheal Hunt sold, so I guess one action nullified the other.
So I am asking the board to each reconsider their individual personal investment strategy and consider buying into their company shares whilst they remain a bargain.
This is commonm practice for directors to show faith in the company they manage and purchasing shares is usually is well recieved by the market.
I dont feel I have add further and await a response, hopefully positive,in due course.
Best wishes.
Freddie

[fredd1eboy] 05/9/2016 07:44

hxxp://www.reneuron.com/investors/analyst-research-and-presentations/

[johnb5] 12/8/2016 22:15

Norbus I don't think Woodford is listening to RF. Update from Woodford today: "ReNeuron, meanwhile, also delivered some very promising pre-clinical data in its retinal stem cell technology, which highlighted the therapy’s safety, tolerability and efficacy profile. Data from its Phase II trial in stroke patients is due to read out towards the end of this year and we remain very excited about this young company’s long-term prospects."

[kwizza] 12/8/2016 12:32

ReNeuron scores coup in stroke drug development bid

11:13 12 Aug 2016

www.proactiveinvestors.co.uk/companies/stocktube/5392/reneuron-scores-coup-in-stroke-drug-development-bid-5392.html

[norbus] 05/8/2016 08:55

Must be down to Rocket Fuel spooking Woodford..

[johnb5] 04/8/2016 15:18

Any thoughts on all these trades going through at mid price? Its been going on for days now. Maybe institutional buying maybe wishful thinking on my part. With +3billion shares out there we need buying for the long term. Any price increase and there's flood of sellers appear.

[stewart_25] 04/8/2016 14:28

yes, very disappointing no share price movement - although it drops like a bomb with no reason... Would like to stay positive that the share price will start to fly as the news and benefit of the treatment is simply immense.

[norbus] 04/8/2016 12:55

Nothing gets published in the Lancer without expert peer review. It goes beyong what you think of as old news; There will be reasons for the lethargy

[fredd1eboy] 04/8/2016 12:12

Aalthough almost all trades are sells the volume is pitifully low. Once we get an interest from institutional buyers and the volume increases demand we will fly.

[small crow] 04/8/2016 11:42

... and no-one is selling.

[small crow] 04/8/2016 09:59

Norbus

It was partly a reiteration of old news, so market lethargy not unexpected. It takes a hell of a lot these days ... across the market!

[easwarareddy] 04/8/2016 09:37

I know. It dropped very fast from 5 or 6p. Yet won't budge up. Even at this low price and good news. Needs some energy from mt

[norbus] 04/8/2016 09:24

something is very odd if market indifferent to the Lancet news

[johnb5] 04/8/2016 09:20

You wonder when the market is going to wake up to the potential here. Particularly exosomes.

[easwarareddy] 04/8/2016 07:56

Really good news

[rayrac] 04/8/2016 07:47

Very encouraging!!

[small crow] 04/8/2016 07:41

Encouraging statement. Both the reliability (with P<0.005) and the magnitude of the effects in the P1 trial bode well for the future. You see so many clinical trials lauded where statistical significance has hardly been achieved and effects are marginal. Looking forward to next set of results at end of year.

[yachtmaster2] 22/7/2016 16:43

Almost got excited today. Holding so many of these now was starting to show a very healthy profit for a while.

[hlp_4u] 22/7/2016 10:18

648k late trade from yesterday gone through at 3.22....all the selling pressure has now gone...get your braces freddie

[hlp_4u] 15/7/2016 14:45

Couple of small buyers appear and price restored on any volume this will move sharply

[hlp_4u] 15/7/2016 13:03

Definitely a forced seller holding this back.....supported by that 723k sale that went through this am... still positive about this Sp once that seller is cleared