Date | Subject | Author | Discuss |
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21/5/2024 17:07 | You can see numerous posts and warnings from me on here over the past year. | ![](https://images.advfn.com/static/default-user.png) nigelpm | |
21/5/2024 17:07 | Screwed in a hole investors.London has gone rubbish, no one is willing to invest anymore. No wonder uk fund sold out.. | ![](https://images.advfn.com/static/default-user.png) neo26 | |
21/5/2024 17:04 | How is anyone surprised? Honestly. | ![](https://images.advfn.com/static/default-user.png) nigelpm | |
21/5/2024 17:00 | Wow that's a huge discount 73% | ![](https://images.advfn.com/static/default-user.png) chester9 | |
21/5/2024 16:56 | There's the placing | ![](https://images.advfn.com/static/default-user.png) epicsurf | |
21/5/2024 16:55 | I now expect a lengthy apology from the usual protagonists. | ![](https://images.advfn.com/static/default-user.png) nigelpm | |
21/5/2024 13:26 | The Hospital for Sick Children, Toronto, Canada, they have had trials there, but have not found any news on it. | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
21/5/2024 12:19 | https://www.sheffield.ac.uk/news/new-mri-scanning-technology-improve-clinical-accessibility-and-advance-lung-disease-diagnosis | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
21/5/2024 08:57 | https://x.com/JMammarappallil/status/1792790782266749138 | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
19/5/2024 00:28 | A typical mri scan would take anywhere between 45mins to 1hr. With Polarean imaging gas takes 10 mins according to Christopher von jako.https://youtu.be/bylX3crjtgs?si=xpjIiWXDT8NW7FBl | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
18/5/2024 13:19 | CEO Dr C von Jako Shares bought NONE Shareholder No
CFO C Osborne Shares bought NONE Shareholder No
Directors non ex
Juergen Laucht Shares bought NONE Shareholder No Frank Schulkes Shares bought NONE Shareholder No Marcella Ruddy Shares bought NONE Shareholder No Dan Brague Shares bought NONE Shareholder No Bill Blair Shares bought NONE Shareholder No
Bastiaan Driehuys Shareholder Yes shares bought at last placing 2021 None
Chairman Ken West Shareholder Yes shares bought at last placing 2021 None
Mr Cyrille Petit rep of Bracco Shareholder Yes Shares bought at last placing Yes
All ( with the exception of Mr Petit) non executives are pocketing director fees over a number of years. None of it is being invested in Polarean shares.
Chairman Mr West has his hands firmly in Polarean's pockets and his own and has received plenty of fees none used to buy shares in Polarean with exception of his 10 year options extension. He didn't even buy at the last placing 2021.
Mr Brague director with his cool $100000 max special marketing adviser money has not bought a single share.
No investormeet scheduled nearly 9 months since the last one No AGM held in the UK to question the directors.
Not much mention of shareholders since previous chairman Mr Allis left or Mr Hullihen both of whom were shareholders and bought at the last placing. | ![](https://images.advfn.com/static/default-user.png) goldbutler | |
16/5/2024 19:18 | https://www.medicaldevice-network.com/news/4d-medical-imbio-us/They will be at the ats, in san diego. | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
16/5/2024 09:56 | https://site.thoracic.org/ | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
16/5/2024 07:45 | This could have been written 3 years ago ! | ![](https://images.advfn.com/static/default-user.png) bertiebingo | |
16/5/2024 07:23 | From pirates last post its so clear the benefit of the tech on identifying lung deficiencies. Without radiation so able to re scan to see affect of medication instead of the historic mri at last choice due to radiation affects. This seems perfect. The world will catch on and investors. It's started. | ![](https://images.advfn.com/static/default-user.png) moontheloon | |
16/5/2024 07:12 | Some great posts Pirates4 much appreciated Thank you | ![](https://images.advfn.com/static/default-user.png) john henry | |
15/5/2024 23:45 | https://ats2024.d365.events/directory/sessions/43e47c96-45a1-48bb-b42b-f7d36f987eec | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
15/5/2024 23:33 | https://iro.uiowa.edu/esploro/outputs/9984275057002771Article OPEN ACCESS PEER REVIEWEDProtocols for multi-site trials using hyperpolarized Xe-129 MRI for imaging of ventilation, alveolar-airspace size, and gas exchange: A position paper from the Xe-129 MRI clinical trials consortium.Hyperpolarized (HP) Xe-129 MRI uniquely images pulmonary ventilation, gas exchange, and terminal airway morphology rapidly and safely, providing novel information not possible using conventional imaging modalities or pulmonary function tests. As such, there is mounting interest in expanding the use of biomarkers derived from HP Xe-129 MRI as outcome measures in multi-site clinical trials across a range of pulmonary disorders. Until recently, HP Xe-129 MRI techniques have been developed largely independently at a limited number of academic centers, without harmonizing acquisition strategies. To promote uniformity and adoption of HP Xe-129 MRI more widely in translational research, multi-site trials, and ultimately clinical practice, this position paper from the Xe-129 MRI Clinical Trials Consortium (https://cpir.cchmc.org/XeMRICTC) recommends standard protocols to harmonize methods for image acquisition in HP Xe-129 MRI. Recommendations are described for the most common HP gas MRI techniques-calibration, ventilation, alveolar-airspace size, and gas exchange-across MRI scanner manufacturers most used for this application. Moreover, recommendations are described for Xe-129 dose volumes and breath-hold standardization to further foster consistency of imaging studies. The intention is that sites with HP Xe-129 MRI capabilities can readily implement these methods to obtain consistent high-quality images that provide regional insight into lung structure and function. While this document represents consensus at a snapshot in time, a roadmap for technical developments is provided that will further increase image quality and efficiency. These standardized dosing and imaging protocols will facilitate the wider adoption of HP Xe-129 MRI for multi-site pulmonary research. | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
15/5/2024 14:37 | https://quibim.com/newsroom/news-and-press-releases/quibim-partners-with-merck-kgaa-darmstadt-germany-to-develop-next-wave-of-imaging-based-diagnostics-for-precision-medicine/https://www.philips.com/a-w/about/news/archive/standard/news/articles/2023/20231026-philips-teams-with-imaging-biomarker-specialist-quibim-on-ai-based-imaging-and-reporting-solutions-for-mr-prostate-exams.html | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
15/5/2024 14:33 | Philips have merged with Polarean and now with Quibim and these.Quibim partners with Merck KGaA, Darmstadt, Germany to develop next wave of imaging-based diagnostics for precision medicine | ![](https://images.advfn.com/static/default-user.png) pirates4 | |
15/5/2024 12:32 | ?NewsroomNewsroomNavigateContact UsCincinnati Children's Images First Clinical Patient in North America Using Novel Xenon GasThursday, May 11, 2023?An image of a Proton MRI scan (left) and an Xe MRI scan (right).Cincinnati Children's Hospital Medical Center has become the first hospital in the nation to image a patient with XENOVIEWTM, a novel xenon (Xe) gas blend that enables a safe and detailed view of lung ventilation, since its FDA approval for ages 12 and older in December of 2022.Nearly 750 children per 100,000 are affected by some type of pulmonary condition such as cystic fibrosis, asthma, or bronchiolitis obliterans. Many of these conditions are detected using a CT scan, a critical tool which, unfortunately, presents a small safety risk in the form of radiation exposure. Until now, there has not been a way to evaluate regional lung function and ventilation quickly and accurately that poses minimal potential harm to pediatric patients.Jason Woods, PhD, director of research in the division of Pulmonary Medicine at Cincinnati Children's, has been investigating a way to alleviate these concerns. For more than 20 years, he has researched Xe gas to pioneer a safer, faster, and more precise method for pinpointing lung disease. This research culminated in the launch of the Xenon-129 MRI Clinical Trials Consortium in 2015 which began exploring the potential of hyperpolarized Xe gas imaged via radiation-free magnetic resonance imaging (MRI) as a standardized tool at other sites."Xe MRI is a safer diagnostic test that helps us better understand where the problem spots are for pediatric patients," says Woods. "It can potentially guide us to the best treatment and help us determine whether a therapy is effective. This type of imaging gives us 3D visualization, so we know how to better intervene with medications or procedures. Xe MRI is a large step forward in assessing lung ventilation."The Xe MRI dose is created through a Polarean HPX hyperpolarization system and administered to the patient in a small delivery bag. Once inhaled, the gas is distributed throughout the lungs and the pattern is imaged via MRI, providing a detailed look at lung ventilation and obstruction. The entire procedure takes place in a single 10- to 15-second breath hold. The gas is then exhaled and begins to leave the body within seconds."The gas increases regional sensitivity and specificity and provides, for the first time, a detailed map of regional ventilation as opposed to a global measure. This enables experts to assess the severity of disease and precisely where disease worsens over time, or where and how it improves with treatment," says Woods. "In a landscape of increasingly personalized pharmaceuticals, we believe this will allow both the patient and provider to understand these changes, improving care delivery."Widespread use of this test could introduce a sea change in pediatric pulmonary care. In the coming years, Woods and the Consortium will continue to promote implementation to make Xe MRI a standard pulmonary diagnostic test. | ![](https://images.advfn.com/static/default-user.png) pirates4 | |